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Science

Investigating Chronic Wasting Disease 314

windows writes "The Saint Louis Post-Dispatch has an article in today's newspaper on efforts by many states to test for chronic wasting disease. The disease affects deer and elk, and is similar to Mad Cow Disease in how it destroys brain tissue giving it a spony appearance under a microscope. Due to the rapid spread of the disease recently, most states are enlisting the assistance of hunters to provide brain stems of deer, to test for the disease. The purpose of this study is just to determine how far geographically the disease has spread. It is not yet understood how the disease is spread or if it is a threat to cattle or humans."
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Investigating Chronic Wasting Disease

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  • by Anonymous Coward
    I wasted my share of chronic... I never thought it was a disease!!!
  • So (Score:5, Insightful)

    by TheFlu ( 213162 ) on Sunday December 01, 2002 @05:18PM (#4789044) Homepage
    They don't know how it's spread or if it will hurt me, but I shouldn't worry about handling items possibly contaminated with the disease? Makes sense...
    • Re:So (Score:5, Informative)

      by sickmtbnutcase ( 608308 ) on Sunday December 01, 2002 @05:20PM (#4789062)
      They know it's carried in the brain and tissue of the spinal cord. If you don't cut into the brain or spinal cord when butchering the animals, you have nothing to worry about. You can handle all the meat from the animals that you want with no effects to you at all.

      • by Subcarrier ( 262294 ) on Sunday December 01, 2002 @05:26PM (#4789103)
        They know it's carried in the brain and tissue of the spinal cord. If you don't cut into the brain or spinal cord when butchering the animals, you have nothing to worry about. You can handle all the meat from the animals that you want with no effects to you at all.

        So how does it spread, then? The elks rub their brain stems together in the throws of passion?
      • Wrong. (Score:3, Informative)

        by TheSHAD0W ( 258774 )
        It affects the nerve tissue, not necessarily just the central nervous system, and nerves pervade the body. Also, while it only seems to affect nerves, that doesn't mean that a virus or prion that causes it isn't present in other body tissue.
      • Re:So (Score:4, Informative)

        by WolfWithoutAClause ( 162946 ) on Sunday December 01, 2002 @06:02PM (#4789286) Homepage
        Yeah, nvCJD is also found in certain organ meats though, spleen, tonsils etc. So you should probably avoid organ meat. But it's a nerve disease, nerves go everywhere in the body, so there's possibly a risk from eating any part of the body; but some parts are far riskier than others.

        Still, there's no evidence that this particular disease can be caught by humans, but personally I would minimise my risk, by having the safer cuts of meat, atleast. YMMV.


        • Still, there's no evidence that this particular disease ...

          There is NO evidence BSE/CJD is an infectious (#1), and little evidence this/these are even a *disease*. There is masses of evidence that Organophosphates poisoning produces exactly the same symptoms, Brain lesions resulting in Neupathy; by a know process Manganese leeching Copper from the brain. One of the British victims of CJD was vegetarian who had not eaten meat for years, did own cats that where treated with Organophosphates flea treatments.
    • Re:So (Score:5, Funny)

      by Qzukk ( 229616 ) on Sunday December 01, 2002 @05:28PM (#4789113) Journal
      Well, you turn the deer brainstems over to the government, and eat the rest of the deer. Five years later, some people knock on your door, and when you answer it, they shoot you and take your brainstem. Then they compare the brainstems, and see whether you contracted this disease from eating the deer you killed.

      Ten years and millions of government dollars later, they announce their research findings: "While it appears that eating deer infected with Chronic Wasting Disease will not cause you to be infected by the disease, our research indicates that deer hunters are at a high risk of sudden death."

    • Duh.. They know how prion-based disease is transmitted... it's through consuming the diseased tissues, largely. And in spongiform disorders, this is the brain/spinal cord tissues/fluids, as far as they know
      So basically, if you kill a deer that might be diseased, don't use/eat any part of the head.
    • Re:So (Score:3, Interesting)

      Seems the researchers are collecting entire heads of deer, and not just brainstems.

      Hopefully we won't have a lot of deer hunters erroneously informed by slashdot's misleading summary; asking the public to harvest the brain stems of these animals wouldn't be terribly wise.

      Fortunately, this being slashdot, basic demographics ensure that won't be much of a problem.

    • IANA pharmacologist. However Organophosphates is known to leech copper from the brain and replace it with manganese, and represent the most credible explanation for BSE in Cows, Scrapie in Sheep and CJD in people.

  • by Anonymous Coward on Sunday December 01, 2002 @05:20PM (#4789060)
    ..I thought I was wasting away because I sit inside reading Slashdot on lovely sunny Sunday afternoons.
  • by Sirion ( 579818 ) on Sunday December 01, 2002 @05:20PM (#4789061) Homepage
    "[CRW] is similar to Mad Cow Disease in how it destroys brain tissue giving it a spony appearance under a microscope."

    This just in: researchers have found symptoms of Chronic Wasting Disease in various Slashdot editors. Details at 11.

  • ...has some hunters wondering if the trophy animal they bag could eventually kill them.

    Of course they could always mount the head on the wall, then one day while they are standing under it the nail lets loose and the antlers of the trophy runs through their neck.

  • Greg Egan (Score:5, Interesting)

    by Jhan ( 542783 ) on Sunday December 01, 2002 @05:24PM (#4789088) Homepage

    Perhaps one of my favorite SF writers, Bruce Sterling, was closer than I thought...

    In "Sacred Cow" he postulated that there was a slower, more insidious form of BSE which only affected humans after decades... Resulting in >80% death tolls in Britain, >60% in the rest of Europe. 50% in the US. 20% in Japan. A modern black plague.

    The western world collapses, India, Japan and China rise to control the world.

    • Re:Greg Egan (NOT) (Score:3, Informative)

      by Jhan ( 542783 )
      Doh! I changed Egan for Sterling in the text but not in the subject... Time for bed...
    • Re:Greg Egan (Score:2, Informative)

      by Morf ( 33787 )
      The idea that there is a slower more insidious form is very strongly backed by studies of Kuru ( a disease of cannibalistic Fore highlanders in Papua New Guinea).

      There were three distinct groups of people who died - people who died in the first wave had one genetic profile, in the middle wave, another , and in the final wave, up to 40 yrs later, a different genetic profile again.

      Also, all those who have died from nvCJD thus far have been homozygous for a gene known to give shorter incuation periods for diseases like this (such as Kuru and the heridary forms of CJD and Gerstmann-Streussler-Schinker).

      Morf (CJD research geek)

  • by shaitand ( 626655 )
    We are too effectively battling disease nowdays, so it's targeting animals instead. Good, let the bastards rot. Besides that the deer population is actually higher than it's ever been. They can afford to lose a few.
  • by NineNine ( 235196 ) on Sunday December 01, 2002 @05:25PM (#4789097)
    I'm chronically wasted. Does this mean they're gonna have to shoot me and test my brain stem. Geez, I hope not. Or, if it has to happen, I hope they do it when I'm really, really wasted. That way I won't feel it. Just an idea. Dude.
  • by Anonymous Coward
    Yet there is a story about disease in deer.

    Good job, Slashdot. Good job.
  • by McCrapDeluxe ( 626840 ) on Sunday December 01, 2002 @05:27PM (#4789111) Journal
    As mentioned in the article, CWD has recently been found in Wisconsin. It's been all over the news here. Hunter turnout is down 20%, I believe.

    Here's [jsonline.com] one article from the local paper.
  • by dochood ( 614876 ) on Sunday December 01, 2002 @05:28PM (#4789116)
    Deer hunting is the best way to keep the herds thin and help prevent the spread of disease.

    Some bunny-huggers out there think they are doing the deer a favor by trying to stop hunting and implementing deer-transfers from heavily human-populated areas, when they may, in fact, be contributing to the problem.

    In Missouri, hunters take about 225,000 deer a year out of about 1 million or so. This taking of about one quarter of the herd has helped keep the numbers fairly steady. This steady hunting pressure keeps the herd at sustainable numbers in most areas.

    The areas in MO that have the worst deer population problems are around the big cities (St Louis, Kansas City, and Jefferson City). People are constantly running into them with their cars in the suburbs. The conservation department tries to encourage bow hunting around these areas by selling up to 5 $5 "urban archery" permits per hunter. But it's hard to hunt (even bow hunt) where people are too close by, because a lot of city-folks seem to have a negative attitude towards hunting.

    dochood
    MO Deer Hunter
    • I agree with you for the most part, but I also would like to say that the "bunny-huggers" don't seem to understand that humans have not only virtually elminated the natural predators of the deer, but we've eliminated their feeding grounds as well. Then people complain on the one hand about the "predatory virulent deer" encroaching on their lovely suburban gardens and freeways, and on the other hand complain about the "bloodthirsty, inhumane hunters" who do no more than their part to keep the population in natural balance as dictated by the conservation society...

      As one who lives in metro St. Louis, I understand the dilemma.
    • Note that deer populations were never a problem before hunters with guns showed up.

      The argument that you should kill deer in order to reduce the occurrence of the disease is rather dubious, not least because it isn't clear that the "disease" is infectuous.

      Calling people "bunny huggers" is like tattooing "I'm an asshole" on your forehead. Go ahead, whatever. (Put more philosophically, it reveals your locus of loyalty without materially contributing to the argument.)

      The claim that hunting stabilizes the population is invented. In fact you don't know why the population is what it is - and neither do I. One way to test it would be to ban hunting completely for a decade or two and see what happens. None too likely in the near future.

      An important fact is that hunting - or something -reduced the population of many species in North America over the last few hundred years.

      The claim that hunting "stabilises" something which was in a long term decline and has recently bounced back is sophistry - it presupposes that we all agree that the populations are stable and claims without proof that they would be less so if hunting disappeared.

      Of course there are still a lot of other factors involved. I suspect that the spread in marginal wooded areas has a lot to do with the increase in deer population.

      The post is a troll.

      • Note that deer populations were never a problem before hunters with guns showed up.


        That's an overly broad claim. However, there is likely a correlation between "humans with guns" appearing and "exermination of wolves, mountain lions, bobcats, and other deer predators".
      • First, it's not that these populations "bounced back". These populations are, as far as anyone can tell, at an all time high. It's more like an infestation in some locations. Second, your argument is dangerous in that it invites only inaction. "Let's just sit around and study something and see if we really understand it." I see the need for study but a more balanced approach might be more effective.
    • Release wolves into the wild again, then. That'll take care of the deer.
    • But it's hard to hunt (even bow hunt) where people are too close by, because a lot of city-folks seem to have a negative attitude towards hunting.

      Well, this may have a lot to do with city-folks not wanting people firing weapons near them, in general. Especially camouflaged yahoos whom are occasionally inebriated.

      My father in law in Missouri has chronic problems with the local red-necks trespassing on his property to hunt, even going so far as to knock his fence down in order to get their SUVs in and tear up the creek bed that runs through his land. The lazy bastards can't even be bothered to get out on foot to "hunt".

      Its also not unheard of for stray bullets to strike residential structures.

      These are probably some of the reasons that contribute to folks' unease about hunting near them.

      And I would say that calling hunting the "best" way to control wildlife populations is at best a matter of personal opinion. I would much rather have a balanced ecosystem with wild predators rather than relying on extremely undependable human intervention.
  • by Kohath ( 38547 ) on Sunday December 01, 2002 @05:35PM (#4789160)
    It's supposed to be News for Nerds, not News for Herds.
  • by t0qer ( 230538 ) on Sunday December 01, 2002 @05:45PM (#4789217) Homepage Journal
    So instead of trying to provide some insightful comment built on reason, i'll just go imaginitive and see what I come up with...

    I'm guessing that the problem occurs first in domestic livestock then moves it's way down to the wild population. This is a great agurment for natural selection VS. controlled breeding, gene manipulation and cloning.

    For whatever reason, us humans have the gall to think we can master in 20 years what took nature millions of years to perfect. Despite natural selection being cruel in both the animal world and human (small geeks get beat up/eat up by jocks) just the fact that it has worked over eons is proof alone that it is far better than any technology we as humans can develop.

    I used to tell this story when I got drunk to people, it's funny so laugh..

    Why alchohol makes you smarter.
    Your brain is like a herd of buffalo. The process of natural selection makes the herd healthier because the wolves will kill the slower buffalo trailing the herd first. By killing off the sick and weak buffalo the herd is left with healthy stock to breed, thus introducing healthier buffalo's into the herd.
    Your brain is like that hurd of buffalo when you drink. The alchahol kills off the slow and weak brain cells leaving only the healthy ones to reproduce, thereby making your brain a faster more efficient machine. This is why everybody feels a little stronger when drinking! /end joke
    That little joke does have grounding in reality in that the domesticated animals were not bred for diesease resistance or agressiveness, but rather for docileness and meat. This in turn has made them more susceptable to dieseases that their wild cousins would normally laugh off.

    Add to that equation the use of antibiotics and steroids in domestic livestock. It's been proven with humans that over time a diesease will mutate where it is no longer killed by an antibody. We then change it a bit, and the diesease mutates yet again. Steroids inhibit the production of white blood cells while strengthening muscles. Steroids don't kill the germ, they just make you feel like you have none. So germs can keep on breeding inside an organism all jacked up on steroids and it wouldn't even know it.

    The hugely scarey thing is humans are now *considering* tweaking with our own genes, and despite that 3lb's of grey stuff we got on top of our heads, unless we irraditate the earth (in which case we ruin it) there is no way we are going to be able to stop the googleplex of 1 celled organisms that inhabit this earth from overthrowing us.

    I guess the moral i'd like to make to all this is we need to "re-teach" ourselves to live in harmony with nature. Just because you destroy a forest, pave it, and put pavement over it doesn't mean you "conquered" nature. If it's not there how can you say it was conquered??

    Just my 2cents.
  • by rossifer ( 581396 ) on Sunday December 01, 2002 @05:49PM (#4789240) Journal
    Chronic Wasting Disease, Mad Cow Disease, and Creutzfeldt-Jakob Disease are all forms of Transmissible Spongiform Encephalopathies (TSE's) and they really ought to frighten you.

    The parts that ought to frighten you don't necessarily seem that bad until all of the factors are taken in at once:

    1) total incurability of infected people/animals.

    2) near indestructability of prions (1100F for hours, etc.)

    3) ability of TSE's to cross species (scrapie in sheep, BSE in cattle, CJD in people, TME in mink, PSE in pigs, etc.) and it's all the same group of diseases. They differ in the speed that they cause damage, but that's about it.

    4) The US meat/poultry industry practice of rendering slaughterhouse remains and *DOWNER CATTLE* into feed for other animals and poultry. This rendering process always includes brain and spinal cord tissue in the resulting product.

    Basically, if the US meat industry hasn't found BSE in cattle, it's because it doesn't want to. The fact that downer cattle are never checked for BSE should piss just about everyone off. When Dr. Richard Marsh at the University of Wisconsin injected US cattle with TME infected US mink tissues, the cattle didn't act like the British cattle, they simply collapsed, looking like any other downer cow.

    The US industry takes those downer cows, never checks to see what might have brought them down, grinds them up, brains and all, and feeds them to chickens, pigs, other cattle.

    The scariest part is that slower forms of CJD (the human disease) look exactly like Alzheimer's and other forms of progressive dementia. In a Yale study, 6 of 46 Alzheimer's patients (13%!) were CJD positive at autopsy.

    CWD (deer, elk, etc.) is almost certainly picked up from raiding contaminated feed meant for livestock. At least, that's my marginally informed position on the topic. It has to be injested somehow and it's a distorted animal protien so these wild herbivorous animals have to be consuming animal proteins to get sick.

    The European Union has now banned all animal products in livestock feed, but the US FDA resists this simple and absolutely necessary step to halt the progress of the perfect pathogen throughout the United States.

    An article that does a much better job of describing these problems and substantiating these arguments is at: "mad cows and englishmen" [disinfo.com]. I hope it worries you and that you tell someone else about it. Even better, tell your congresscritter about it and what you think about it.

    Regards, Ross

    • by Turing Machine ( 144300 ) on Sunday December 01, 2002 @06:03PM (#4789297)
      but the US FDA resists this simple and absolutely necessary step to halt the progress of the perfect pathogen throughout the United States.

      Err... you're a little behind the times. The FDA banned mammalian protein in livestock feed way back in 1997 [fda.gov].
      • I've posted a pointer to the actual regulations further up in the discussion. They have not banned animal protiens in livestock feed, there are plenty of loopholes in the definition - most notably any animal protien which has been prepared for human consumption. Since cooking a meat-on-the-bone meal doesn't kill prion-based illness, you've got a huge infection vector right there.
    • The European Union has now banned all animal products in livestock feed, but the US FDA resists this simple and absolutely necessary step to halt the progress of the perfect pathogen throughout the United States.

      Simple economics with a slightly evil twist. Cattle grow faster on a high protein diet -- bone meal -- rendered animals. You force them to eat grain and it costs a lot more money and time to get them large enough to slaughter. That's probably on the order of billions of dollars yearly. There's a lot of lobbying power in that amount of money.

    • 2) near indestructability of prions (1100F for hours, etc.)

      3) ability of TSE's to cross species (scrapie in sheep, BSE in cattle, CJD in people, TME in mink, PSE in pigs, etc.) and it's all the same group of diseases. They differ in the speed that they cause damage, but that's about it.

      I would really like to see something supporting the idea that a protein can survive 1100 degrees F for any amount of time. For comparison- picked up from various web searches- Aluminum melts around 1220F and Zinc at 787F while fiberglass roofing ignites without exposure to flame at around 900F and rigid PVC pipe does so at 850F. The extreme end of thermophilic bacteria is around 113C (235F) so infectious agents surviving intact for extended periods at 1100F more than highly unlikely.
      There were studies that found that prions survived 30 minutes at 134C (273F) in an autoclave but later studies found that 138C (280F) with or without a strong alkaline bath disinfected them. It's now part of nursing curriculum: Decontaminating the Indestructible Prion [nursingceu.com]

      Anyone interested in the diseases and cross-species aspects might want to read Paul Ewald's Evolution of Infectious Diseases [isbn.nu] and Plague Time [isbn.nu].


      - technik
      • Please, someone mod the parent up. A protein at 1100 F? Boiling off a lot of the bound water associated with most proteins will badly denature them by the time you get up around the 200 F mark. (There are definite exceptions, however--prions possibly included.) In air, I would go so far as to say that any protein will oxidize (if not burst into flame) at 500 F or less. Just having all that thermal energy kicking around will facilitate rapid rearrangements of proteins, even under an inert atmosphere. Sure, prions are harder to inactivate than most other biohazards, but they still obey the laws of physics.
  • Keep yourself safe. (Score:4, Informative)

    by quitcherbitchen ( 587409 ) on Sunday December 01, 2002 @05:56PM (#4789263)

    This is a decent article that addresses how to clean a deer with caution and respect to CWD:

    Cut with Caution: How to safely field dress deer [startribune.com]

  • by dagg ( 153577 ) on Sunday December 01, 2002 @05:59PM (#4789275) Journal
    ... "The deer had been acting strangely, so conservation officers shot it and sent samples of its brain to Galesburg to be tested."

    To think, just a few years ago, that sentence would have stopped at "shot it". Now after shooting it, we send it's head to Galesburg. Civilization has come a long way.

  • by robbo ( 4388 ) <slashdot@NosPaM.simra.net> on Sunday December 01, 2002 @06:03PM (#4789296)
    Interesting that this is a story today, because yesterday a group of Canadian elk ranchers announced a class action suit against the Canadian gov't for failing to take action against the spread of CWD. More details are here [cbc.ca].
    • Sounds like a pre-emptive strike by ranchers to get better livestock price guarantees if/when their herds are ever ordered destroyed. An Elk farmer in Minnesota had his entire herd destroyed and his compensation was the market value of the animals, which sounds fine, until you find out that the Elk market has gone through some gyrations in the past few years, and Elk prices are way down.

      Many ranchers are "stuck" holding a lot of Elk herds that are worth a lot less than when they were bought, meaning that you need to hold them, breed them and sell a lot more Elk to make back your initial investment. If you sue the government now, you might be able to get a negotiated agreement to refund more than the current market price for Elk if they have to wipe out your herd.

      On one hand, I feel for the guy who put his whole nut into the "Elk Ranch" concept and is being essentially wiped off the financial map. On the other hand, I can't help think its special-interests-via-the-courts welfare.
  • FAQ on CWD (Score:3, Informative)

    by sickmtbnutcase ( 608308 ) on Sunday December 01, 2002 @06:03PM (#4789300)
    WI DNR site has a FAQ and other info on CDW here [state.wi.us]

  • Yeah, it's a typo. As in "SponeBob". But before I read the article I did spend a couple fruitless minutes trying to look it up elsewhere on the internet, in a weird spinoff of RTFM. [Slaps forehead]
  • I was eating my steak, and it was like, "moo," "moo," and then it was, like, half of my brain stem was gone.
    And I was like: "Huh?"
    It devoured my brain.
    It was really a good brain.
    It was kind of a... bummer.

    Seriously... give this a consideration [veganoutreach.com].

  • Yeah that's right. Let's build a better bovine. One that's immune to this shit. And anyone who wants to take their chances out in the woods with fuzzy wuzzies and eating pine nuts can have at it. Just so long as they don't breed or breathe near me.
  • How can state governments test for Chronic Wasting Disease... I thought most state governments suffered from it!
    • Wisconisn sure does, our state deficit last year was something like $6bil, so now we dont have the cash to research this stuff.
  • Chronic Wasting Disease

    What happens to geeks after 14 straight hours of playing Quake!
  • by Dave500 ( 107484 ) on Sunday December 01, 2002 @06:39PM (#4789486)

    If you don't know already, one of the more interesting things about Spongiform diseases is that they are not caused by bacteria or viruses, but by prions.

    A prion is just a protein that is for all pruposes identical to one that would appear in your body natually, a neurochemical is one example. However, prions have a subtle difference in their 3 dimensional structure, which means that they don't carry out their job quite as the "normal" version of that protein should. Furthermore, they seem to have methods of altering any "normal" versions of themelves that they encounter into the prion form.

    Since they are virtually the same, the body does not tend to regard them as a hostile agent, so they are free to multiply and spread about the body. Since they are a protein, they can interact with various parts of your body (in particular, your brain), and cause various things that should not happen. Its these unplanned interactions that lead to the diseases that they cause.


    For more info:-
    http://www-micro.msb.le.ac.uk/335/Prions.html [le.ac.uk]
    http://www.rkm.com.au/BSE/ [rkm.com.au]
    http://www.mad-cow.org [mad-cow.org]

  • Yeah, Al Kieda, that notirous terrorist guy has spiked the food chain with horrible prions that will kill all the non Islamics!

    But all is not lost -- since these prions are such resiliant substances, maybe we can build jet engines out of them and bomb stupid old Al out of existance.

    In other news, doctors have reported a huge increase in the number of people now qualified to seek a presidential candidacy or Senate seat.

    They're putting this down to a brain wasting disease too.
  • by MAurelius ( 565652 ) on Sunday December 01, 2002 @10:52PM (#4790600)
    The Milwaukee Journal-Sentinel published this story in July about three friends who died. Two died of CJD and one of Pick's disease, which is sometimes hard to distinguish from CJD. The kicker is, these three friends hunted together and ate together at game 'feasts' back in the 1980s and 1990s. The Infectious Disease doc mentioned, Dennis Maki, is very well known and respected in the medical community here in Wisconsin. Here's the link:

    http://www.jsonline.com/news/State/jul02/60546.asp

    As previous posts have mentioned, prions are nearly indistructible. Multiple cases of human CJD have been proved to be transmitted by surgical instruments that were 'sterilized' by standard techniques after being used on a patient later diagnosed with CJD. My point is: we are well advised to be extremely cautious where potential transmission of prions is at issue.

    The previous post regarding 46 brain biopsies of Alzheimer's patients, among which 6 cases were 'positive for CJD' is puzzling. The microscopic look of the two diseases is completely different. CJD brain tissue looks like Swiss cheese under the microscope, while Alzheimer's brains show neurons replaced by 'neurofibrillary tangles.' These look like bits of brown stringy stuff where the neuron body used to be. Clinically, however, the diseases both cause dementia. Normally the time course of CJD, from first symptom to complete dementia, is much shorter (weeks to months) than Alzheimer's (years).

    Hope this gives people some things to think about.

    Marcus

  • New Plaque Indeed (Score:2, Informative)

    by Anonymous Coward
    New Plague Indeed.
    What many here are joking about is the beginning of a plague like has never been witnessed before.
    Initial infections were first noted in New Guinea in the '50's. Called Kuru then it was transmitted as a result cannibalism, (Natives would eat dead relatives) and having 100% mortality. Since that time Scientists have known about prions and the danger they represent but have always maintained prion disease was self-limiting (100% mortality) within one generation.
    The problem is the disease just won't go away: Witness England in the 1980's. There, again, it was felt the disease was the result of feeding animal protiens infected with Prion to herbivores. The public response by government officials was the same: destroy infected animals in a big show to convince the public 'something was being done' but in fact the real problem is of course self--limiting (100% mortality). Besides, had not the ignorant British fed animal protein to herbivores nothing would have come of it at all.
    Now we enter the 1990's and our old friend is back--only now something very ominous has occurred. You see a Missouri Deer hunter, up until about 1998 or so considered himself lucky if he could get a 'Doe Tag' or a 'Bonus Tag' and thereby legally take more than one deer per season. But now, all of the sudden, all a hunter need do, in Missouri, is simply request a bonus Tag and he will be given one - for a modest fee of course. Now in Missouri no deer Hunter need be lucky to bag all the deer he wants.
    What may we infer from all of this?
    1) Prion have not gone away.
    2) They are not self limiting-but they are 100% fatal.
    3) Prions are now in our food chain.
    4) No viable explanation has, as yet come forth as to how North American 'wild' herbivores have contracted prion disease.
    5) Certain sectors of the Government are more than mildly alarmed hoping the American Deer Hunter will buy them some time to figure what to do. (At what cost to the hunter and his family?)
    6) World Health organizations are now holding their collective breath and watching Great Britain for possible massive human prion infections to begin to manifest.

    Now for the real Soothsayer of Doom stuff:

    Fast forward to the year 2025--England has been quarantined for seven years (nothing goes in nothing goes out) The crematories are running night and day. In Asia mass starvation has begun as prion infection has entered the Piscean as well as other food chains. In Europe and the United State martial law is declared when the lies and dissembling is no longer effective. As the deaths and bodies pile up, diseases thought long dormant receive new life and also join the rampage in an unrelenting slaughter which will leave half to three-quarters of the earths animal life forms dead.
    Its already started and nothing is going to stop it-certainly not the Missouri Deer Hunters. ...and if you are one of the few left in 2025 ,not much outside the memory of your own loved ones is going to mean much I would think.

    Of course we could agree I am just another raving, lunatic, crackpot soothsayer of doom, forget about all this prion crap and go grab a hamburger at McDonalds :)

    Just another Anonymous Coward
  • BSE, or Mad Cow Disease, as the press has dubbed it, appears to have been transferred from sheep to cattle. About twenty-five ago Great Britain began allowing feed processors to use steamed sheep bone meal in cattle feed. BCE began to appear in bovines a few years later.

    The disease in sheep is known as scrapie and has been known for around 250 years, according to the U. S. Department of Agriculture. [usda.gov] The USDA even has an active program intended to eliminate scrapie. I am not aware of any definite link between scrapie and Creutzfeldt-Jakob disease, but I wouldn't be surprised if there were.

    How scrapie was transmitted to elk and deer doesn't seem to be clear, but deer are distant relatives of goats and sheep. It does seems clear that politics is the reason for the name Chronic Wasting Disease, just as the press has insisted on Mad Cow Disease, instead of referring to the true origins of the disease and admitting that it originated in sheep.

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