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Science

Redheads Need More Anesthesia than Others 484

Natural redheads need 20% more anesthesia than other people report scientists. "Redheads are likely to experience more pain from a given stimulus and therefore require more anesthesia to alleviate that pain." said Dr. Edwin Liem of the University of Louisville in Kentucky. Anesthesiology is still very much a mystery to scientists, and picking the right dosage that keeps someone out without killing them is still very much an art. Studies like this will help them determine how anesthesics work and why.
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Redheads Need More Anesthesia than Others

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  • by President A. Lincoln ( 600204 ) on Tuesday October 15, 2002 @01:52AM (#4451856)


    They're just more pissy, thats all. Blondes go under real fast because theres not as much brain to put asleep.


    Cheers,
    Abe.
  • I'm going to dye my hair, print this article for my dentist, and I'll be FLYIN HIGH!

    Thanks Slashdot!

  • by boa13 ( 548222 ) on Tuesday October 15, 2002 @01:54AM (#4451866) Homepage Journal
    Do they need 20% less stimulation? :)
    • by Anonymous Coward on Tuesday October 15, 2002 @02:07AM (#4451932)
      My wife is a redhead. For her, more stimulation is better. (She's getting a Sybian for christmas. If you don't know how STIMULATING one of those can be... well, you need to do some "research".)

      Another interesting thing... one orgasm is 'it' for her. After she has finished, she is so sensitive that she cannot tolerate being touched sexually. Perhaps that is somehow related to this research... (nerve sensitivity?)
      • by cscx ( 541332 ) on Tuesday October 15, 2002 @02:17AM (#4451965) Homepage
        She's getting a Sybian for christmas

        Sounds like someone isn't getting the job done...
      • by Anonymous Coward
        "research done"

        Sybiant [google.com]

        thanks google

  • by bradkittenbrink ( 608877 ) on Tuesday October 15, 2002 @01:55AM (#4451872) Homepage Journal
    so that's why I spend so much on alcohol...
  • About red hair (Score:5, Interesting)

    by SexyKellyOsbourne ( 606860 ) on Tuesday October 15, 2002 @01:57AM (#4451881) Journal
    Red hair is a phenotype particular only to scarce areas of Northern Europe, mostly in Scotland, Ireland, and Scandinavia -- even there, it is not entirely common.

    Blazing red hair is a very recessive trait created entirely by past inbreeding in Europe -- and past inbreeding is a common heritage for Europe, as well, since most Europeans can trace their ancestors back to a very small group of perhaps a dozen Ice Age survivors. It requires not only a 3rd-level hair gene (0-3 for red), it also requires a very low lightness gene (0 for platinum blond, down thru 12 to pitch black), which is extremely recessive as well.

    Since the trait is so recessive, the extinction of redheads is predicted to be sometime in the late 21st or early 22nd century, due to population implosion of the native populations of northern Europe and the traits being lost due to interbreeding with those with dominant dark-haired traits.

    It's no surprise that redheads have other strange recessive genes that we are only now discovering -- this could prove to be very interesting, and could help a lot in future gene therapy.
    • Re:About red hair (Score:3, Interesting)

      by johnstein ( 602156 )
      wow, i shoulda posted my response below as a reply here. (redheads losing their hair sooner). in fact i now remember a friend i knew from school who had light redish-blonde hair, however he kept it cut very short since his hair was thinning too.

      heh, this revelation probably isn't so insightful for those geneticists out there, but it makes me more and more relieved that my mother's brown hair genes won the battle of my head.

      -John
    • Re:About red hair (Score:5, Interesting)

      by The Tyro ( 247333 ) on Tuesday October 15, 2002 @02:16AM (#4451960)
      There is considerable genetic variation among racial groups with respect to many drugs.

      For example, certain persons of american indian descent have an enzyme deficiency that results in certain paralytic drugs having a greatly prolonged duration of action. Naturally, this is not always something you want in a normally rapid-on/rapid-off neuromuscular blocking agent...

      There are also racial tendencies with regard to what classes of blood pressure medications work best with certain racial groups.

      This kind of variation (along with anatomic variants) can make the practice of medicine very challenging. Don't go into medicine if you don't like surprises!
      • Re:About red hair (Score:5, Interesting)

        by AndroidCat ( 229562 ) on Tuesday October 15, 2002 @07:28AM (#4452596) Homepage
        And if you have the gene for Malignant Hyperthemia Susceptibility, certain anaesthetics cause every muscle in your body to spasm, your core temperature skyrockets and you die. Don't talk to me about surprises!

        Luckily, when my brother was having his appendix out, it was by the chief surgeon of Toronto General, who just happened to be a friend of Dr. Britt, who at the time was one of the foremost researchers into MHS. He knew exactly what to do. (Ice bath, keep the heart going...)

        I almost certainly have the gene too, but the 100% test involves sampling a chunk of muscle tissue from a leg. I'll pass!

        • Re:About red hair (Score:3, Informative)

          by MAurelius ( 565652 )
          Thanks for posting your experience with MH, which is every anethesiologist's nightmare. I know, because I'm an anesthesiologist. Obviously, it's critical that everyone like you with a strong family history of this disease, tell their anesthesiologist before any surgery!!


          At the risk of being off-topic, I also wanted to say that people like you can be safely anesthetized without triggering an MH episode. I just had a patient like you last week with a similar family history. At our hospital, we have a special vapor-free anesthesia machine, which supplies only oxygen and Nitrous Oxide (N2O), which are both safe. We use muscle relaxants that are known to be safe (succinlycholine is NOT safe) and in my case last week I ran infusions of propofol and alfentanil for the six-hour lumbar spinal fusion (patient in prone position). The young man (37 y/o) did fine and woke up with no memory of the surgery and relatively little post-op pain. The patient had an epidural catheter for post-op pain control, using morphine by continuous drip.


          Marcus

    • by Quirk ( 36086 ) on Tuesday October 15, 2002 @02:21AM (#4451970) Homepage Journal

      You wrote: "since most Europeans can trace their ancestors back to a very small group of perhaps a dozen Ice Age survivors."

      I know this is the case for my family (german/danish). We've traced our family line on both sides to a brother and sister who barely avoided a slow cold death by crossing the Alps into the area around Cannes.

    • Re:About red hair (Score:5, Interesting)

      by Anonymous Coward on Tuesday October 15, 2002 @02:33AM (#4451997)
      > Red hair is a phenotype particular only to scarce
      > areas of Northern Europe, mostly in Scotland,
      > Ireland, and Scandinavia -- even there, it is not
      > entirely common.

      Nope. I know from friends and relatives that red hair is also found among North Indians (especially among Kashmiris), though it is certainly in the minority. My own hair is dark brown with red highlights. But then again, Indians seem to have a wide range of phenotypes in everything from eye, skin, and hair color to the shape of eyes and faces.

      Indians in many ways appear often to be more a collection of thousands of micro-ethnicities than a single ethnic group. Though these micro-ethnicities shade into each other at the boundaries, there is a lot of variation between them. It would be interesting to see if the results presented in this study (conducted on people with European ancestry) could be replicated with Indians that have red hair. After all, it could be that this has nothing to do with red-hair in general, but only with a particular way of getting red hair.
    • Re:About red hair (Score:5, Interesting)

      by Jugalator ( 259273 ) on Tuesday October 15, 2002 @03:21AM (#4452103) Journal
      this could prove to be very interesting, and could help a lot in future gene therapy.

      It could also help archaeologists understand the predecessors of Homo Sapiens better, if the research saying the "redhead gene" might come from neanderthals is true.

      I mean, if redheads are slightly more sensitive to pain somehow, I think it is very likely that neanderthals were as well. And this is things we would never know from "common", material studies alone.

      Besides, isn't it thought that blondes are making room for brunettes as well, for reasons similar to what you mention?
    • OH no - SAVE THE REDHEADS!!!

      (No redheads were harmed in the making of this post.)
  • Anesthesiology is still very much a mystery to scientists, and picking the right dosage that keeps someone out without killing them is still very much an art. Studies like this will help them determine how anesthesics work and why.
    Yeah, there are these guys that live down the hall of my dorm that said something like that. They keep telling me "Man, we're like, you know, doctors or scientists or something. Yeah..."
  • People were homo sapiens (smaller, of african origin, but had a seagoing society eventually) and neanderthal man (bigger, located primarily in europe).

    At about 40,000 BP homo sapiens invaded Europe and killed most of the Neanderthals and interbred with the remainder. A few were chased into Scotland, and people of pure redhaired Scottish descent are the closest we still have to neanderthals (I'm not kidding).
    • It's interesting you mention it, since I actually read in the news [dispatch.co.za] that someone had come up with redheads perhaps coming from neanderthals. I don't know if the scientist had the same theories as you, but it's apparently a thought that has struck more than one that has done some research.

      Another quote:

      "Oxford researchers believe that ALL redheads inherited the gene from European Neanderthals. Based on rate of gene mutation, Oxford says the redhead gene appears to be much older than Cro-Magnon man in Europe. The accepted explanation is that the Celtic tribes had a strong remnant of Neanderthal blood caused by Cro-Magnon/Neanderthal interbreeding"
    • by pieterh ( 196118 ) on Tuesday October 15, 2002 @03:37AM (#4452132) Homepage
      At about 40,000 BP homo sapiens invaded Europe and killed most of the Neanderthals and interbred with the remainder.

      Alas for this theory, the study of mitochondrial DNA shows that there are no traces of Neanderthal DNA in modern human populations, anywhere. Nor is there any evidence that homo sapiens sapiens waged war of any kind on Neanderthals.


      It was probably much simpler: modern humans disturbed the Neanderthal ecosystem so much that the old races retreated to mountains and swamps, giving us the myth of Giants. If modern humans mated with Neanderthals (and this is quite possible), their offspring were sterile.


      Modern human variation (including the two extremes of red/blonde and dark brown) all developed recently, about 25,000 to 50,000 years ago.

      Finally, it is quite possible, likely even, that variations in human coloring are not caused by interbreeding but by sexual selection. Fashion, if you will. Gentlemen still prefer blondes.

  • Very True (Score:5, Informative)

    by enneff ( 135842 ) on Tuesday October 15, 2002 @01:58AM (#4451886) Homepage
    "Anesthesiology is still very much a mystery to scientists, and picking the right dosage that keeps someone out without killing them is still very much an art."

    This is a very, very good point. If you're ever going to have an operation which requires a general anesthetic, make sure you find out who the anesthetist is going to be, and whether they're any good.

    Recovery rates can hinge hugely on how appropriately anesthetised you are - too little and your body can go into shock, too much and you'll find yourself out of action for up to a week!

    • Re:Very True (Score:3, Informative)

      by Anonymous Coward
      Recovery rates can hinge hugely on how appropriately anesthetised you are - too little and your body can go into shock, too much and you'll find yourself out of action for up to a week!
      Not only that, but please, please follow the guidelines given to you by your doctor or anesthetist.

      I work in the office of a maxillofacial surgeon (jaw and to some extent tooth surgeon). All of our patients are given an anesthesia guide during their initial consultation, which tells them to eat a full meal 24 hours before surgery, and not to eat or drink anything 12 hours prior to the event. I can't tell you how many times I've heard patients wake up in the middle of surgery - in extreme, loud pain - because they decided that a "little snack" or a can of Dr. Pepper 2 hours before the procedure was no big deal. Folks, it is a big deal. Anesthesia is administered based upon your body weight and the estimated duration of the procedure (among other factors). In all cases but emergencies, it's also administered on the assumption that you've got an empty stomach.

      Anesthesia is not a joke. If not administered properly, it can swing to both extremes; either leaving you wide awake and screaming during surgery, or leaving you comatose or perhaps dead. I realize this is straying off-topic, but it needs to be said. Pay attention to your doctor or anesthesiologist and _do_what_they_say_ before surgery involving anesthesia. No matter what color your hair is. :)
      • Re:Very True (Score:2, Interesting)

        wake up in the middle of surgery - in extreme, loud pain

        I don't know about the exact type of the anesthesia used in maxillofacial surgery, but doesn't that suggest a somewhat poor anesthesiologist. As far as I know, the depth of the anesthesia can and is monitored during the operation and can be increased if necessary. Increased heart rate, blood pressure, sweating, muscle tonus and frowning are all indications of insufficient anesthesia. Since the operation apparently does not involve muscle relaxants (they were able to scream) it should be even easier to detect these signs.

        I've been under the knife several times (knee, eye, shoulder and wrist) and have never had any problems with anesthesia except in the case of the shoulder operation which was at first attempted in local anesthesia as the massive amount of lidocaine caused an allergic reaction.

        • Re:Very True (Score:3, Informative)

          by mgv ( 198488 )
          As far as I know, the depth of the anesthesia can and is monitored during the operation and can be increased if necessary.

          There is no reliable way to monitor the depth of anaesthesia as yet. Several companies sell equipment that purports to do so, but none of them are certainties and the companies often do not reveal the algorithms that separate awake from asleep.

          The incidence of awareness during anaesthesia is about 1:2000 anaesthetics, although most of them aren't the severe "in agony but cant move" type of awareness. Most are some form of recollection (not necessarily painful) of some period during the operation.

          Still the incidence is too high to be acceptable.

          Michael
      • Re:Very True (Score:3, Informative)

        by malkavian ( 9512 )
        Hmm... If I remember aright, waking up in the middle of an op in extreme pain is NOT caused by snacking before you have the anaesthetic.
        The anaesthetic is a muscle relaxant, and as such, also relaxes the muscles that prevent the contents of your stomach going back out the way they came.
        Thus, if eat beforehand, you effectively vomit out the contents of your stomach.. This is not good.
        I'm not an anaesthatist, but my GF is.. Perhaps I can get her to post later and give the more detailed skinny on this.

        Malk
      • Re:Very True (Score:4, Informative)

        by aswang ( 92825 ) <aswang@nOSpam.fatoprofugus.net> on Tuesday October 15, 2002 @09:41AM (#4453260) Homepage
        Some clarifications to the risks of anesthesia:

        Aspiration can happen after the procedure, when you're waking up and the endotracheal tube is still in place. Once the anesthesia wears off, the gag reflex kicks back in, and you start to vomit. If there's something in your stomach, there's a good chance it'll get into your lungs, and then you have a 30% chance of dying.

        While less likely than aspiration, food can affect the half life of anesthesia. If you've eaten something that either induces liver enzymes or acts as a competitive inhibitor of liver enzymes, it will be harder for the anesthesiologist to predict when it will wear off and harder to tell if they are giving you too much.

        And it doesn't matter if you're not actually screaming in pain. If the anesthesia is too light, it can adversely affect the outcome. While you might not remember the event because your hippocampus is soundly asleep, pain receptors and reflex arcs are some of the first systems that come back online, so to speak, and if you happen to jerk around while they're cutting you because the anesthesia is too light, you might just lose some anatomical structure that you might have wanted to keep.

      • Mod Parent down!!! (Score:4, Informative)

        by spineboy ( 22918 ) on Tuesday October 15, 2002 @02:33PM (#4455666) Journal
        I've been a surgeon for 7 years and I've NEVER had a patient wake up or tell me that they've "woke up" during a case - ever!! About 1 case in 60 or 70 a patient gets a little "light" and they start to react to the surgery (a muscle twitch). Other than that it's lights out!.. What usually happens is that people go in and out of consciousness AFTER the surgery is over and they remember the post-op pain. I've had plenty of patients in the recovery room ask when is the surgery going to start!!
        Anesthesia has nothing to do with your stomach contents being full or empty. People can vomit during induction of anesthesia and thats why we want empty stomachs (aspiration pneumonia=bad!)

        I don't know what the maxillofacial office worker is talking about - unless they're giving their anesthesia solely as an oral sedative. In that case it might take a little longer to work.
    • by EvilStein ( 414640 ) <spam@BALDWINpbp.net minus author> on Tuesday October 15, 2002 @02:37AM (#4452003)
      But if they screw up the dosage, you could end up having a really damn good time!

      I remember getting my tonsils out.. they told me "Ok, you're going to feel a little light headed in about a minute.." Minute. Yeah, right. About 0.543534 seconds later I remember feeling this really wicked feeling. I tried to fight it.
      I failed.
      I tried to say something, but all that came out was a horrible squawk.

      Oh, MAN that felt good.. heh.
  • by DougJohnson ( 595893 ) on Tuesday October 15, 2002 @01:58AM (#4451888)
    And more frequently
  • Not enough info (Score:5, Insightful)

    by J4 ( 449 ) on Tuesday October 15, 2002 @01:59AM (#4451892) Homepage
    That's a pretty broad conclusion considering they only used one anesthetic.

    insert irish drinking joke here
  • Asking in a delicate way, is this perhaps related to natural redheads being more excitable? All kidding aside, I have noticed that redheaded women are more passionate and prone to enjoy extended foreplay and even just simple touch.

  • by drinkypoo ( 153816 ) <drink@hyperlogos.org> on Tuesday October 15, 2002 @01:59AM (#4451897) Homepage Journal
    They get more out of it.

    You know who you are. *mwa*

  • by sssmashy ( 612587 ) on Tuesday October 15, 2002 @02:03AM (#4451914)
    In a nutshell, redheads are likely to experience more pain from a given stimulus...

    Especially if the stimulus involves a hot sunny day at the beach.

  • by cmckay ( 25124 ) <cameron.mckay@co ... u ['ora' in gap]> on Tuesday October 15, 2002 @02:04AM (#4451919) Homepage
    I'm a natural redhead, and I find this article quite interesting. I've never had a problem with anesthesia before, and I've had a few surgeries under general anesthesia (tonsilectomy, wisdom teeth removed, um... okay maybe just two). I never woke up or felt pain during the procedures (at least not that I remember).

    I also don't feel like I have a lower tolerance for pain than my less-fortunately-hair-colored friends. I burn myself on a semi-regular basis (soldering), and that's not too bad.

    Now, I'm curious:
    If the world is 20% more painful for me, is it also 20% more pleasureful?
    • oh crap... my poor mom! She's a redhead too, and she wanted to do the "natural childbirth" thing with me... owwwwwwww!

      That had to have been one spicy meatball.
    • While I admit that I'm both red-headed and arrogant (or so my wife says anyway), my limited experience upholds this study.

      A few years ago I had a wisdom tooth pulled and part way through the procedure, I started squirming because it hurt. The dental assistant was quite surprised and told me that I shouldn't be feeling it.

      Personal thery: I bet the actual cause is not the hair genese but some other genes that come out of the same genetic background. This would explain why some redhead's don't have this trait (they've either not had that gene passed on or else came from a differing redhead group). Personally, I have a lot of Danish and a bit of Irish heritage, so I'm guessing that one or both of those groups would have that trait.
  • I Doubt It (Score:5, Interesting)

    by e8johan ( 605347 ) on Tuesday October 15, 2002 @02:05AM (#4451922) Homepage Journal
    This proves that correlation studies can be used to find many results. You can find that statistically, red-heads feel pain easier, but this does not say anything about any single individual.
    There is a reason to why one says "lies, damn lies and statistics. Correlation has been used to "prove" many things such as racist ideas (superiority due to colour), intelligence from weight etc. A good correlation between two parameters does *not* prove that they are connected!
    • Re:I Doubt It (Score:5, Interesting)

      by JMemmert ( 564338 ) <memmert@nosPam.jpmdesign.net> on Tuesday October 15, 2002 @04:01AM (#4452182) Homepage Journal
      I concur with the above statement and would like to add some more comments.
      I am a dark blonde with no redheads in my family for roughly three generations back (No jokes about inbreeding here, please. ;-))
      My tolerance for novocaine, diazepam (valium) and a host of other anesthetics is about 12x normal (tripple the dosage, 1/4th of the duration) and has puzzled more than one specialist. The result of careful analysis has shown that my body eliminates most anesthetics at a much higher rate than normal.
      My pain level is no higher or lower than average though my sensitivity to stimuli is much higher than average (I can read a photocopy with my fingertips, sometimes even writing in ink).
      Based on that point of data, I'd say that equating sensitivity to stimuli to sensitivity to pain, as it has happened in many posts is probably not a good (i.e. valid) idea. I should be screaming of pain most the time if this were true.
      Only empirical evidence with a very limited set of data, I know, but as e8johan stated: "but this does not say anything about any single individual".
      The next question is whether sensitivity to pain has any relevance to the effect of an anesthetic.
      If I remember correctly, local anesthetics work vastly different from general anesthesia by targeting different areas in the body.
      [1] [capanes.com] states that Novocaine et al. supress the transmission of stimuli through the nerve while general anesthetics act in the brain ([2] [sciencenews.org] has something about some anesthetics triggering the sleep cycle, for others, I don't know).
      Desflurane now is a geneal anesthetic, acting in the brain. So, any reference to "I can do this, I can do that" that does not duplicate the function of a geneal anesthetic is useless...
      This means that my impressive tolerance for Novocaine et al. does not have any significance for the research performed as it targets a different type of anesthetic. The same goes for many other comments along the same lines, including alcohol.
      Alcohol acts as an inhibitor ([3] [chemcases.com] states: "Alcohol acts primarily at the GABAa receptor to facilitate its action, thus in essence creating enhanced inhibition.") but does not have a sufficiently strong effect that the person affected could consciously compare it to a geneal anesthetic...
      As for the use of alcohol as geneal anesthetic, which would be the next logical argument... it's not been very effective prior to complete unconsciousness and the level and speed of alcohol absorption plays a huge role. That also rules out any comment along the lines of "I can drink more than an ox".

      I won't ask for people to check what they're writing for relevance... after all, I enjoy many of the comments I read here, but it is considered bad style to criticize the work of others without enough commonalities between the work and the critical remarks.

    • Re:I Doubt It (Score:3, Informative)

      by Alsee ( 515537 )
      A good correlation between two parameters does *not* prove that they are connected!

      It prooves they are correlated. :)
      I'd consider that a connection. I assume you meant to say it doesn't prove causation.

      -
    • Re:I Doubt It (Score:3, Informative)

      by Fjord ( 99230 )
      I agree with you, kind of. The problem here is that they are trying to assign causation: redheads need more anethetic because they feel more pain. There's nothing here that supports that. Instead, taking a needle and pricking people with verious hair colours would determine a hair-color/pain senstitivity link. There are just too many other factors, most notably how redheads process the anethesic. Maybe they need more because they have a higher tolerance for outside chemical changes.

      But it does show that redheads need more anethetic on average, that's what correlation is.
  • by rhodesbe ( 614799 ) on Tuesday October 15, 2002 @02:06AM (#4451927)
    I am a redhead who is dating a redhead, and who has red haired relatives all over my family tree. I can tell you that redhead pain sensitivity is no more or less than anyone else. You can believe what you want, but just remember: If you tell an irishman he can't handle pain, he'll cut his own balls off to prove it, then he'll shove them down your throat and stomp your ass into a mudhole so you remember. Believe me.
  • by Anonymous Coward on Tuesday October 15, 2002 @02:10AM (#4451939)
    "Redheads are likely to experience more pain from a given stimulus and therefore require more anesthesia to alleviate that pain."
    It took scientists to figure this out?! I thought we'd all known for years that redheads, especially ladies, experience more pain from the simple act of a stranger saying hello than they do from passing a kidney-stone. Why, the last time I tried to say "hey, how are you?" to a lovely redheaded girl, I thought I was about to lose my manhood in a horrific accident! Short fuses, and all...

    Then again, these were scientists from the University of Kentucky. Who better to study redheads, than rednecks?

    On a serious note, this doesn't surprise me too much. Redheads are well known for having extremely sensitive skin. Ever see a redhead with a tan? If you have, it was a rarity, most redheads go straight from pasty-white to fire-engine red; freckles (another sensitivity based reaction to the sun) are more common among redheads than folks with locks of other colors. So it seems logical that this would extrapolate to other areas of pain and sensitivity.

    Bart Wilkins
  • by The Bungi ( 221687 ) <thebungi@gmail.com> on Tuesday October 15, 2002 @02:11AM (#4451943) Homepage
    Taco: holy shit guys, there are more stories about Micro$oft [with emphasis on the '$' - Eds] than Linux today!!1!!

    Chrisd: I know.

    Taco: well, do soemethiung abouttit man!!1!

    Chrisd: Some poor schmuck submitted a storie a few minutes ago about the effect of anesthesis on readhe...

    Taco: yeah, post that. Do it!!1!!

    Chrisd: Are you sure???

    Taco: Do it, dammit!!!1!1!

    Chrisd: OK...

    • Well, at least its not from Timothy, so we're pretty sure its not a repost.

      Join the newest gameshow on /. Who can find the previous incarnation of a story that Timothy just posted? Winner gets 50 karma.

  • Blondes vs. redheads (Score:2, Interesting)

    by Farang ( 552254 )
    From the article: "Red hair is the first visible human trait...linked to anesthetic requirement." Not sure what "anesthetic requirement" actually is, but I recall that years ago it was reported that blue-eyed people have a higher tolerance for pain. Whether that lowers their anesthetic requirement... I believe "anesthesia" means "without sensation," in other words unconscious. So what are we talking about here? Do we mean the ability to tolerate perceived pain, or how easily one slips into unconsciousness after being drugged? Are the two related?
    • That's strange.. about 10 years ago my optometrist told me that blue-eyed blondes are somewhat more sensitive to pain, especially related to the eyes. He said he has more trouble fitting blue-eyed blondes for contacts (especially hard lenses), and that they tended to experience worse night vision and painfully poor tolerance for high light-levels, expecially with contacts in.

      Then again, he could have just been trying to make me feel better when I wimped out on hard lenses (I could only open my eyes in darkened rooms when I had them in, even after two weeks of "getting used to them"). I'm fine with soft lenses, though!
  • by zephc ( 225327 ) on Tuesday October 15, 2002 @02:22AM (#4451974)
    Red-Haired Girls

    [Setting: A Tree-Filled Field in the Woods.]
    [The It's A Fact Girl jumps in front of the camera and into a close up.]

    It's A Fact Girl: It's A Fact.

    [The It's A Fact Girl runs back into the woods, in sped up motion. When she stops, Scott as The Queen of England leans over in front of the camera and smiles as she addresses it.]

    Scott: Hello. When I was a little girl, if a child was born with red hair, she was considered irreparably evil and drowned as a witch. It's a fact!
  • by BoBaBrain ( 215786 ) on Tuesday October 15, 2002 @02:39AM (#4452009)
    Redheads Need More Anesthesia than Others

    What section is this, ChrisD's lurve tips?
  • I'm blonde, but can see light tinges of red in my facial hair...it comes from my grandmother who's a natural strawberry blonde; my uncle is definately a redhead.

    What I've noticed is that when it comes to alcohol, caffiene, and other intoxicants/stimulants, I need a much higher dosage to feel the effects. I have a higher alcohol tolerance than antyone I know, matched only by a binge drinker who weighs 60 lbs more than I do.

    I don't think that I'm more susceptible to pain either. Friends frequently refer to me as the guy with the 'asbestos hands'. If anything, I have a higher pain tolerance than most.

    Drugs, just like pain and other nerve stimulus (I have very strong willpower over being tickled even though I am quite ticklish) seem to require stronger amounts to affect me to the level as the average populace.

    I guess I can attribute this to my redhair or Dutch genes, being one and the same.
    • I'm with you (Score:5, Interesting)

      by Wee ( 17189 ) on Tuesday October 15, 2002 @03:37AM (#4452135)
      What I've noticed is that when it comes to alcohol, caffiene, and other intoxicants/stimulants, I need a much higher dosage to feel the effects. I have a higher alcohol tolerance than antyone I know, matched only by a binge drinker who weighs 60 lbs more than I do.

      I don't think that I'm more susceptible to pain either. Friends frequently refer to me as the guy with the 'asbestos hands'. If anything, I have a higher pain tolerance than most

      I don't buy it either. I'm pretty blond-ish (I've got reds in my beard and mixed in with a bunch of light colors in my hair) and I'm rather light-skinned. I'd describe myself almost exactly as you describe yourself. I even have a friend like yours with a higher tolerance than myself (although he's recently stopped drinking). I hardly feel pain and when I do it's usually too late.

      I've broken all of my fingers (most twice), most of my toes, a few ribs, both ankles and both wrists. I have a 10" long "depression" in my skull from when I cracked it playing football in the house at age 6 (dove for a "pass", hit the little metal striker plate on the door jamb). I had a double hernia at 18 months old. When I was growing up, I'd say I had a cast/splint on something for about 3 months out of every year. For the longest time, everyone thought I was really fragile. Turns out I just didn't feel it when something broke, and so never had that "Don't dive into a tackle with your fingers sticking out" negative reinforcement. I'd break something and not notice until I couldn't bend a joint or it hurt later on when I moved it in some way.

      I've even broken fingers and not known it. I once went in to the emergency room for a sprain or whatever and they discovered an old break I didn't remember. That was when I did go into the emergency room. After a while, I stopped because it was too expensive (and I had a full set of splints anyway). That's why to this day I can't touch type; I took typing class three times but could never complete it (twice for fingers, once for wrist).

      I don't get cold very easily. I mean, wiping ice off a windshield is no big deal. Hot isn't terribly bothersome, either. Reaching into a campfire to move a log around or into water to get corn (or whatever) isn't something I normally think about not doing. It takes a couple more beers than most people to get a head of steam going, and I never ever throw up from drinking. I'm not ticklish. When I get a splinter, I just take it out with a scalpel and a small incision because it's easier and quicker than digging around. A healthy splash of rubbing alcohol afterward isn't bad at all. I've had a tooth (accidentally) removed without anesthesia. That hurt a lot. It takes a couple Vicodins to do any good. Curisouly, aspirin works very well for most stuff. When I get a headache, it's migraine-quality.

      Long story short, I don't buy the relationship between hair color/skin tone and nerve responsiveness. I know I'm only a sample of one (and a highly biased researcher :-) but the theory just doesn't hold water. I am not more susceptible to pain than most people.

      BTW, I haven't broken anything in four years. If the lack of negative physical feedback didn't teach me to be careful, the feedback of "no type, no money" sure did. I still do stuff like play paintball, it's just that I tend to think a little more carefully about what I need to do before I do it.

      Oh yeah, I'm not Dutch. Scotch-Irish/English, with a teensy bit of Polish.

      -B

      • I have a 10" long "depression" in my skull from when I cracked it playing football in the house at age 6 (dove for a "pass", hit the little metal striker plate on the door jamb).


        I think we've found the reason for your apparent lack of pain receptors!
    • by exploder ( 196936 ) on Tuesday October 15, 2002 @01:29PM (#4455153) Homepage
      What I've noticed is that people seem to have a great need to feel unique, and making up wacky-ass medical anomalies seems to be a popular means. "Oh, tylenol doesn't work for me..." or "My body eliminates anesthetics at 4x the normal rate" or "anesthetic gel actually CAUSES me pain" or this git above. You're not a beautiful snowflake, get over it.
  • by mysticalreaper ( 93971 ) on Tuesday October 15, 2002 @02:49AM (#4452038)
    I've got red hair, bright red. I've got freckles too, though fewer now than when i was a kid. I'm 20 now. Anyways, the only thing that i've noticed about having red hair is that you get sunburnt easily. Other than that, nothing. In fact, i think i have a higher than average tolerance for pain. It's hard to compare levels of pain with others, of course, but I don't find myself hurting more than others at all.

    The article states that, in general, redheads felt more pain. But what if i don't? What if i feel less pain than average? Directly linking hair-color to pain reception is tenuous at best, and it seems like doctors messing with my anestheisa beacuase of my hair color could be bad, with the threat of coma.

    I've never heard of hair color affecting ANYTHING before. Sure race affects some things, like reactions to certain drugs, and diseases. Sex and age as well will determine the best treatment. But hair color? What about eye color, does that factor in?

    It seems like this is a broad generaliztion, and i don't think this can be the deciding criteria for pain reception. I don't buy it this first time round, if only based on personal experience.
  • To participate as volunteer redhead for the research.:

    We are looking for women aged between 19-40 to take part in our research aiming to help us understand fundamental questions such as which systems in the brain produce unconsciousness and which modulate pain perception. The research is conducted using empirical studies. Basicly, we will stick you with nails and see how you react. Please send your applications to...

    I would believe the test group contains a bit more than average of masochist individuals. :)

  • by Dynedain ( 141758 ) <slashdot2&anthonymclin,com> on Tuesday October 15, 2002 @03:02AM (#4452065) Homepage
    Another comment now that I've read the article.

    They claim their findings indicate redheads are more susceptable to pain.

    Based on what is presented in their article, an equaly valid point can be made:
    anesthesia is less effective on redheads.

    Both are legit conclusions from the presented evidence. Either redheads could feel more pain, or their bodies may not absorb/be affected by intoxicants as much.

    Explains why the redheaded cultures are known for impressive drinking skills.
    • by Anonymous Coward on Tuesday October 15, 2002 @04:27AM (#4452228)
      Yep. fair. I'm *very* redheaded -- mom and dad both very red.

      When I had to have a major op as a kid, they had to give me a whole bunch of anesthetic to put me out. The normal "count down from 10" act didn't work. I had to have three attempts that I remember. When I had my lower wisdom teeth out, the normal 5 injections in the jaw went up to 40 injections before I lost enough feeling to start, and they had to keep topping me up, and it still hurt.

      I'm also extremely resistant to ibuprofen, paracetamol, codeine, morphine, and a whole bunch of other pharms. Aspirin's the only one that works, and I need about twice the dose of someone else my age/height/build. My alcohol tolerance has always been extremely high. Marijuana has no effect on me whatsoever. I'm allergic or resistant to most medicines I've ever had.

      More importantly, my mom has have _woken up_ during a major operation. Luckily they noticed quickly and put her under again. She also has similar resistance to pharmaceutical drugs.

      I'd have to go with "anesthesia is less effective on redheads". I'd also flag it (Score: -1, Well Duh). More research from the Institute of the Blindingly Obvious.

      Posting anonymously, because I've already moderated some of the more bigoted posts in this article. Some people don't realise the reason redheads tend to have short tempers is the amount of shit they get from bigots while growing up -- something the bigots obviously don't do.
  • Anecdotal experience (Score:5, Interesting)

    by bollucks ( 450288 ) on Tuesday October 15, 2002 @03:12AM (#4452088)
    I'm a specialist anaesthetist and for many years we have anecdotal reports of redheads being more resistant to anaesthesia. We certainly find clinically that this is the case and also there is information that they are more likely to suffer a severe allergic reaction (anaphylaxis). Many of these anecdotal reports are what start these interesting studies initially conducted on small samples and lead to serendipitous discoveries of how things work.
  • by Ilan Volow ( 539597 ) on Tuesday October 15, 2002 @03:15AM (#4452093) Homepage
    Keep in mind that you'll have to make the tranquilizer dart 20% heavier to make Carrot-Top less annoying

  • by pjammer ( 90700 ) <pjammer.livejournal@com> on Tuesday October 15, 2002 @03:22AM (#4452104) Homepage
    Patient: Uhm - WHAT are you doing?

    Doctor: Well, Miss Everhart [askmen.com] I need to verify that you're a 'real redhead' before we proceed with the operation to ensure proper dosage ...
  • Well the theme is quite interesting but the story is, as usual relatively superficial, I don't get up what level of investigation they reached. So I fear that soon the Mass Media will start publishing such stories:

    Eggheads can be knock down only with a hammer...
    Shaking melonheads as a new form of anesthesy...
    Lemonheads give always a twisted smile after receiving the approporiate dose of anesthesic...
  • hemorrhage (Score:2, Informative)

    by yellowcat ( 561852 )
    My mother used to work as a nurse in the delivery wards and every time they had a red-headed woman coming to deliver, they would put a hemorrhage watch on her. Seems that red-headed ladies were far likely to bleed during birth than ladies with other color hair. Anecdotal evidence, but useful still.

    FYI she worked at Piedmont Hospital in Atlanta, Georgia.
  • by Goonie ( 8651 ) <robert,merkel&benambra,org> on Tuesday October 15, 2002 @04:09AM (#4452196) Homepage
    Wonder if the results are generalizable to men as well.

    I vaguely recall reading somewhere that male and female responses to pain are somewhat different (beyond the obvious differential responses to anaesthetics caused by different body weight). Any of the anaesthetists who've posted care to comment?

  • by main() ( 147152 ) on Tuesday October 15, 2002 @04:35AM (#4452242)
    > "Redheads are likely to experience more pain from a given stimulus and therefore require more anesthesia to alleviate that pain."

    Huh? I can't think of anything more likely to *induce* pain than listening to that man-faced, pop-singing gasbag, Anesthesia.

    Si
  • by _outcat_ ( 111636 ) on Tuesday October 15, 2002 @07:38AM (#4452634) Homepage Journal
    ...and I have found this to be true in my case. Whenever I go to my dentist he's always surprised how much anasthetic I need. I get the dosage. We wait like ten minutes or so, and it's still not numb. We wait longer. Still nothing. Finally he gives me another dose. Two hours after the filling/procedure/whatever NO PAINKILLERS exist any longer anywhere in my body, and my mouth hurts.

    Maybe this sensitivity has a correlation to the stereotypical "redhead temper." I know I'm a bit prone to fits of rage myself. (Yeah, okay, I've got a horrible temper and no one should ever be a passenger in a car that I'm driving because a sweet little redheaded girl turns into a demonic monster from hell behind the wheel screeching all kinds of obscenities especially when I'm in New Jersey but that's another stereotype for another day. I digress.) I'm such a wuss about pain, so I might have just started reacting more to negative things. Hence the temper.

    I don't know, just my two cents..
  • by AssFace ( 118098 ) <`stenz77' `at' `gmail.com'> on Tuesday October 15, 2002 @07:57AM (#4452696) Homepage Journal
    And no - I am not about to say some racist thing.

    I just recall in my days of competitive running that I was taught at the OTC that people with genes from one side of Africa have certain body makeups and are mostly fast twitch fibers, and people from the other side are mostly slow twitch.

    What does that have to do with any of this? The odd thing that they also noted was that natural red heads had nearly identical makeups to the fast twitch section of people that they studied in Africa.
    This meant that if you were at a track race and were looking at the top runners winning a sprinting race - the odds were going to indicate it more likely that the people of African decent (aren't we all if we go back far enough?) would most likely be genetically from the same area, and the white people would most likely have red hair.
    And once I started looking for it, I was impressed that it actually rang true - lots of fast Irish guys.

    I've never seen much mention of anything pointing out red heads since that study until now - usually hair color isn't thought to mean much in the grand scheme of things (aside from my preferring blondes).
  • Me at the dentist (Score:3, Interesting)

    by macdaddy ( 38372 ) on Tuesday October 15, 2002 @08:09AM (#4452751) Homepage Journal
    My dentist has always told me that I take an incredibly high dosage of the stuff they shoot in your gums when you have cavities filled. When they pulled my wisdom teeth last year, the pulling took about 10 minutes, max. Getting me numb pushed through 2 of his other appointments. Usually he gives you some shots and goes to work on someone else and returns when he's done there. That way the shots have time to take effect. Well when he did mine, he gave me a little extra like normal. Then went on to the next person. He came back and started poking around, asking if I could feel it. I could feel it and told him. More shots. He left again. Came back. Still could feel the prodding. More shots. He left, came back. Finally it was numb enough to procede. I always have needed a lot of that stuff to get numb. He could have simply played a tape of my old english teacher talking and I would have been right out. Nope. Always wants to do it the hard way. :-)
  • Pheromones (Score:3, Interesting)

    by Robotech_Master ( 14247 ) on Tuesday October 15, 2002 @08:16AM (#4452774) Homepage Journal
    I found an article on the 'net some time ago which noted that blondes and redheads produced different (more effective?) pheromones than brunettes. It was quite an interesting article, from about the mid 1970s; unfortunately, when I try to google on it now, all I find are human pheromone perfume advertisements.
  • by twoslice ( 457793 ) on Tuesday October 15, 2002 @09:12AM (#4453060)
    If your an anesthetist, do you get to check if she is a real redhead before the operation? Cause, I mean that would be a really cool job!
  • by ellem ( 147712 ) <ellem52@gmai l . c om> on Tuesday October 15, 2002 @10:33AM (#4453589) Homepage Journal
    For the little red haired girl in accounting...

    Yesssss my precioussss

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