Biotech

Scientists Made a Cell From Scratch For First Time (cnn.com) 38

AleRunner writes: The first fully synthetic cell ("SpudCell") has been created in the Department of Genetics at the University of Minnesota. Strictly speaking, it's described as a "cell-like system constructed entirely from known chemical components that can perform a complete cell cycle." It is able to replicate, but only for approximately five generations.

The key advance is that the cell is "built entirely bottom-up from individually purified, non-living components," although it still contains material from E. coli bacteria. "PURE is a defined mixture of 36 purified enzymes from E. coli bacteria," including ribosomes, that provides the infrastructure for genetic replication.

CNN has an article on the advance, including interview material with Professor Kate Adamala, who led the research. "I know the full ingredient list of the cell. I know exactly what chemicals, what molecules, at what concentrations," she said. "It is fully defined, which means we can engineer it."
"Humans did not create life," notes an anonymous Slashdot reader. "Researchers call it a constructed cell, not 'life created in the lab' but a 'genuine milestone on the road toward that question.' It lacks full autonomy (needs feeding, no independent evolution)."

Special thanks to Slashdot readers kemosabi and AleRunner for submitting the story and additional sources, including reports from The New York Times and The Guardian, as well as information from the University of Minnesota Twin Cities.
NASA

NASA Wants To Send Spare Nuclear-Powered Mars Rover To the Moon (space.com) 22

An anonymous reader quotes a report from Space.com: NASA provided an Artemis update today (June 30), announcing new lunar landing contracts for its Moon Base initiative and a surprise new possible rover mission that could be headed to the moon's south pole. During the second monthly update that NASA has provided for its moon base plans, the agency named Astrobotic, Firefly Aerospace and Intuitive Machines as the providers of four robotic landers that will deliver scientific payloads to the surface of the moon, as NASA tests and expands the technologies needed for a permanent human outpost. "This is this drawing on the playbook that worked very well for NASA during the 1960s," NASA Administrator Jared Isaacman said during the livestreamed update, explaining the experiential approach to a crewed lunar return. "We didn't just jump right to Apollo 11."

Isaacman also announced the potential repurposing of an engineering development model built to mirror the agency's Perseverance and Curiosity rovers on Mars. "There is another," Isaacman said, quoting Yoda's line from "Star Wars: The Empire Strikes Back." That test rover is called PROMISE, short for "Polar Rover for Observation, Mapping, and In-Situ Exploration" (though it was formerly known as Optimism). PROMISE was developed at NASA's Jet Propulsion Laboratory (JPL) in Southern California, where it has been used as a test platform for fixes or commands that engineers want to try on the ground before permanently sending them to Perseverance and Curiosity. Now, NASA wants to send PROMISE on a mission of its own. Though sending PROMISE to the moon would leave Perseverance and Curiosity -- both of which remain active on Mars -- without an Earth-based testbed, Isaacman thinks it would be worth it. "We've had years now of experience operating the two rovers on the surface of Mars, and we've got this hardware that the taxpayers have invested a lot in," he said. "So the question was posed: 'What if we send it to the moon?'"

With a little refurbishment, PROMISE would help advance NASA's lunar plans, Isaacman added. Like Perseverance and Curiosity, the test rover is powered by a radioisotope thermoelectric generator (RTG), which converts heat from naturally decaying radioactive material into electricity. So it wouldn't require sunlight to operate -- a real benefit on the moon, where most locations experience long stretches of darkness. (NASA plans to build its Artemis base near the moon's south pole, which is thought to harbor an abundance of water ice and also has a relatively complex lighting environment.) The other robots currently in the works to launch on future missions to the moon, including the landers announced during today's update, are all solar powered. Through 2029, NASA hopes to launch up to 20 such missions as part of the CLPS (Commercial Lunar Payload Services) initiative to support the first phase of the agency's moon base plans, and the landers announced today will be some of the first in that lineup.

Space

The Vera Rubin Telescope Begins Surveying Our Cosmos (nytimes.com) 43

The Vera C. Rubin Observatory has begun its 10-year Legacy Survey of Space and Time, using the world's largest digital camera to image the entire southern sky every few nights. The project is expected to catalog billions of stars and galaxies, track changing and transient objects, and generate an enormous dataset for studying dark matter, galaxy formation, asteroids, and unexpected cosmic phenomena. The New York Times reports: "This is the end of a 30-year wait," said Phil Marshall, the deputy director of the telescope's operations at SLAC National Accelerator Laboratory in California, in a statement to The New York Times. "It's a major milestone for us." Astronomers expect this collection of data, known as the Legacy Survey of Space and Time, to revolutionize their knowledge of our galaxy's birth, the invisible matter permeating the cosmos, what shaped the universe into the structure it has today and more. According to Dr. Marshall, the survey is designed to see everything, "even the things we don't know we're looking for yet," he said.

The team behind the observatory, a joint effort funded by the U.S. Department of Energy and the National Science Foundation, unveiled several images of the cosmos that were jampacked with celestial goodness -- a peek at what the Rubin could do -- last year. Since then, scientists have been busy conducting final tests and reviews of the telescope's operations and systems. According to Bob Blum, the director of Rubin operations at the National Optical-Infrared Astronomy Research Laboratory, the team has also been hard at work ensuring that the telescope can operate reliably in different environmental conditions for the next decade.

Science

Claude Science is Here, Antibiotics Designed by Text Prompt Among Applications (genengnews.com) 45

Anthropic has launched Claude Science, an AI workbench that connects more than 60 scientific databases and tools through a single interface. Through the platform, Basecamp Research is making its EDEN models available for tasks such as designing antibiotic peptides and predicting vaccine targets from simple text prompts, though the results still require laboratory testing before clinical use. Genetic Engineering and Biotechnology News reports: In a Claude Science demo, Oliver Vince, PhD, co-founder at Basecamp, uploaded a sample patient microbiology report. When given a simple natural language prompt, the platform designed peptides, predicted their efficacy, and provided a shortlist of candidates most likely to succeed in experiments in minutes. While generating human-ready antibiotics at the click of a button is still a step away, Vince said democratizing these tools is a powerful first step, particularly for researchers in regions where accelerated computing infrastructure is not readily accessible. "Most models require you to be a computational scientist," Vince told GEN Edge. "Now, potentially any clinician in the world can chat with Claude and design an antibiotic that may work."
Space

Scientists Think Neptune and Uranus May Not Be the Ice Giants We Imagined (gizmodo.com) 42

The planets Neptune and Uranus may be better described as "magma-ocean giants" rather than "ice giants," according to a team of researchers from the University of California. Gizmodo reports: While the Voyager flyby confirmed the planets' classification as ice giants... [a]s the least explored planets in the solar system, the two planets have never been thoroughly investigated. Therefore, scientists aren't sure where the planets originally formed in the early solar system or the reason for their wildly chaotic magnetic fields. A long-standing hypothesis suggests that both worlds have a hydrogen/helium atmosphere that covers a vast mantle of ices, made primarily of water, ammonia, and methane, with a rocky core. The new study, however, notes that the three-layer model of an ice giant's interior structure is not the only way to explain the properties of the two planets.

The researchers also point out that objects found in the Kuiper Belt, which are thought to preserve evidence of the material in the outer Solar System where Uranus and Neptune formed, are primarily composed of rock rather than ice. For the recent study, the researchers simulated different models for the interior processes and composition of Uranus and Neptune. The model that best fits Uranus's and Neptune's different properties suggests the two planets have a well-mixed magma ocean with dissolved hydrogen at the bottom and a hydrogen-dominated envelope at the top. The model suggests that at high pressures, hydrogen gas can dissolve into magma, forming a well-mixed fluid. This mixing might help explain Uranus's and Neptune's density, which has traditionally been interpreted as evidence for an ice-rich interior.

The article notes that the theory "could also help scientists understand the interior structure of sub-Neptune planets in the Milky Way, which have thus far remained a mystery."
Earth

Trump-Shuttered Climate Change Site Now Back Online In Nonprofit Hands (theregister.com) 109

Donald Trump shuttered the web site Climate.gov in 2025, cutting off public access to climate information from America's National Oceanic and Atmospheric Administration (NOAA).

But "former members of the site's team have brought much of it back at a new domain," reports The Register: "Trusted climate information should not disappear when politics change," Climate.us managing director Rebecca Lindsey said of the new platform in a press release. Lindsey, who previously served as the Climate.gov program manager and lead editor, told The Register in an email that she and one of the web developers responsible for the site were the first to be caught up in government purges when DOGE swept through the department in late February 2025... Created in cooperation with sustainability nonprofit accelerator Multiplier, Climate.us aims to be an independent alternative to its old .gov, and many of the former NOAA crew behind the previous website have teamed up for the new initiative to "keep climate information accurate, accessible, scientifically rigorous, and useful for the people who rely on it."

Climate.gov, which now redirects to a NOAA page about climate but which hosts none of the data the shuttered site used to contain, was taken offline in July 2025 following a Trump executive order prioritizing "gold standard science...." arguing that prior climate science models relied on worst-case scenarios, which somehow meant the public availability of 15 years of climate data and reporting ought to change...

All of the content that was purged from the .gov is now back, along with blogs from experts, climate status reports, maps and data pathways, and national assessments of climate change as well. Lindsey told us that rapidly changing political winds have led her to believe that the government isn't the right place for that mission to continue, and that she would have concerns about returning the site to federal management if a future administration changed its position on climate change... Lindsey said that the Climate.us team will continue with the same mission it had before the Trump administration attempted to quash it: Getting climate science in front of the public in a manner that's understandable so they can make their own decisions about how to respond.

Space

Spain-Backed Fund Joins FOSSA's Sovereign Satellite Communications Push (spacenews.com) 11

Spanish startup FOSSA Systems "has raised about $10.5 million to expand its connectivity constellation," reports Space News, noting some funding is backed by Spain's government: The support from the Spanish Society for Technological Transformation (SETT) comes a year after the fund injected 14 million euros into Spain's Sateliot , which is also developing a satellite connectivity network with security and defense applications. Spanish private investment firm Kibo Ventures led FOSSA's funding round, the six-year-old venture announced June 24, bringing its total raised to date to nearly 20 million euros.

The proceeds will help fuel FOSSA's push beyond the tiny picosatellites it once used to connect low-power monitoring devices toward larger cubesats in low Earth orbit, enabling additional sovereign communications and space-based intelligence capabilities... The company's funding round follows a wave of investments this year in European ventures planning to develop sovereign space capabilities, including Austrian propulsion startup Gate Space, which secured 6.3 million euros earlier this month from a European Commission-backed accelerator program.
"Our goal is to establish FOSSA as a European benchmark in sovereign space infrastructure," said Julián Fernández, FOSSA's CEO and cofounder.

Earth

France's Heat This Week Was Worse Than a Dire Scenario Imagined For 2050 (msn.com) 161

There's a deadly, record-breaking heat wave spreading east across Europe, reports the Washington Post — and it's even worse than a dire earlier forecast: The forecast was recorded in 2014 as part of a campaign coordinated by the World Meteorological Organization (WMO) that invited about 60 presenters worldwide to imagine a weather report from the year 2050. In one clip, Ãvelyne Dhéliat from French television network TF1 presented a hypothetical scenario of high temperatures 36 years into the future — during a heat wave in a warmer climate in 2050... One of the maps that Dhéliat shared was lit up in shades of orange, filled with temperature predictions of 40 degrees Celsius (104 degrees Fahrenheit), reaching as high as 43 degrees Celsius (109.4 degrees Fahrenheit).

But it turns out, it didn't take 36 years for those imagined temperatures to be reached — and even exceeded. The heat on Wednesday alone, when the temperature soared as high as 112.3 degrees Fahrenheit (44.3 degrees Celsius), exceeded the 2050 projections in 19 out of 34 locations across mainland France — far sooner than some may have expected. Some places surpassed those hypothetical future temperatures by more than 20 degrees Fahrenheit. It's part of a dramatic shift in heat wave frequency across the country. Half of the heat waves observed since 1947 have occurred since 2010. "By 2100, heat waves could last up to two months continuously," the country's weather agency, Météo-France, said this week.

It was hotter in France on Wednesday than in Las Vegas and Phoenix and just two degrees Fahrenheit shy of what was observed in Death Valley, California. An estimated less than one percent of the planet was hotter than France's hottest place... [T]he heat dome, which will linger into early next week, is only part of the story. This type of extreme heat is becoming more common as the planet warms, especially in Europe.

Climate scientist Robert Rohde said in a post explaining the heat wave's causes that France and Western Europe should expect many more heat waves like this over the coming decades. "This isn't a fluke, but simply part of the new normal," he said.
Thanks to Slashdot reader fjo3 for sharing the news.

Science

Max Planck Slapped With Two Paper Retractions By Suspected Rogue Algorithm (science.org) 21

Max Planck won 1918's Nobel Prize for physics. Yet two of his papers were retracted — a move now being criticized by Yves Gingras, a historian of physics at the University of Quebec and Mahdi Khelfaoui, a fellow historian of science at UQ Trois-Rivières. Science reports: The papers, both quietly retracted in 2011, originally appeared in the early 1940s in Naturwissenschaften, a German journal now owned by publishing giant Springer Nature. After some sleuthing, Khelfaoui determined one of the Planck pieces, a philosophical essay from 1942 titled "Sinn und Grenzen der exakten Wissenschaft" ("Meaning and Limits of Exact Science"), about how to achieve certainty in scientific knowledge, had also appeared in two other journals and been reprinted twice in books. Repackaging the same work multiple times is considered "self-plagiarism" and frowned upon today — the practice produces copyright conflicts and inflates scholars' publication records. The Naturwissenschaften site gives "copyright violation" as the reason for the retraction.

Yet publishing identical material in multiple journals was widespread before the internet. "Science was more fragmented" then, Khelfaoui says. "You wanted different audiences ... to have access to your work." The practice was especially common for luminaries like Planck. Albert Einstein did the same (but escaped retractions). Springer Nature's "anachronistic" application of modern standards to a 1942 paper "distort[s] the historical record," Gingras and Khelfaoui argue in a preprint posted last month on arXiv. Any concerns about copyright violations are largely moot anyway: Because Planck died in 1947, his works are in the public domain in most countries.

Gingras was especially incensed that Springer Nature deviated from the normal practice of merely slapping the word RETRACTED across the digital version of the paper while still allowing scholars to read the text. Instead, the publisher posted a blank white page with the cryptic phrase, "This article has been withdrawn due to article violation." Springer Nature is nevertheless still selling the empty PDF for $39.95. Suzanne Scarlata, a chemist and biochemist at the Worcester Polytechnic Institute and editor-in-chief of The Science of Nature, as Naturwissenschaften is now known, had not heard about the retractions before being contacted for this story... Scarlata suspects Springer Nature's internal policing software removed the paper and posted the retraction notice unilaterally, without human supervision: "I think it just happened with their algorithm," she says. "It's a mistake they should probably rectify."

A second Planck paper was apparently removed because its response to a 1940 paper had used an identical title.

Thanks to our long-time Slashdot reader He Who Has No Name for sharing the article.
AI

Scroll Burned in 79 AD Volcanic Eruption Finally Deciphered Using AI (smithsonianmag.com) 50

When Mt. Vesuvius erupted in 79 A.D., it buried hundreds of papyrus scrolls. They were rediscovered in the mid-1700s, remembers Smithsonian magazine, "the only surviving collection of its kind from the Greco-Roman world..."

"But when scholars tried to unroll them, the carbonized manuscripts crumbled to dust." Every generation that followed faced the same dilemma: They could wait for technology to advance, abandoning hope of reading the ancient texts in their own lifetime. Or they could try to open the scrolls themselves — and risk destroying them.

In recent years, researchers have settled on a third option. Using advanced imaging and artificial intelligence, they're deciphering the scrolls without needing to unroll them at all.

The Vesuvius Challenge has accelerated the process by turning it into a public competition, complete with cash prizes. In 2023, a student won $40,000 for deciphering a single word — "purple" — from an unopened scroll. Later, contestants would identify 2,000 Greek characters from one scroll ($700,000) and the title of another ($60,000). Now, for the very first time, researchers have recovered all surviving text from a single scroll. The nearly five-foot-long segment includes roughly 20 columns of ancient Greek philosophy, accessible for the first time in nearly 2,000 years.

"The tech actually does look like magic, but it's not," Brent Seales, a computer scientist at the University of Kentucky, said at a press conference. (The article points out that Seales partnered with two Silicon Valley investors in 2023 to launch the Vesuvius Challenge, and is now hailing "the restoration of lost voices from the ancient world." Seales has been working on virtually unwrapping the scrolls since the early 2000s. The process involved imaging the bundles of papyrus using technology similar to CT scanners, isolating thin layers and then stitching them together.... "We've developed a systematic and a repeatable approach," Seales told the audience. "Now it's only a matter of time until we read all of the scrolls."
Medicine

Non-Invasive Stimulation of the Brain Ended Opioid Addiction, Cigarette Craving (jpost.com) 37

The Jerusalem Post reports that doctors at Haifa's Rambam Health Care Campus "have successfully treated their first Israeli opioid addiction patient using an experimental noninvasive brain technology, easing him through withdrawal in just 20 minutes..." [T]he team of specialists at the Haifa medical center intervened in the electrical activity of an area of the patient's brain called the nucleus accumbens, the core of the brain system responsible for feelings of satisfaction, pleasure, and reward. The treatment, based on technology from the Israeli company Insightec, is similar to the one used to treat symptoms of essential tremor and Parkinsonian tremor, under MRI control. In this case, the treatment was carried out with the help of a new technology that performs noninvasive neuromodulation, without heating or burning tissue, and allows stimulation in the same area of the brain to increase or suppress activity...

"Tests carried out a week later produced negative results for opioids and other substances," [said Dr. Lior Lev-Tov, director of the functional neurosurgery unit in Rambam's neurosurgery division and the one leading the new study at the medical center.] "The patient himself reported a craving score of zero out of 10 for using the drug, and even another side effect, a drastic drop in the desire for cigarettes, from three packs a day to just a few cigarettes, and with no urge to use alcohol. In other words, in a treatment that lasted about 20 minutes net, our patient was completely freed from an extreme dependence that had accompanied him every day for years. This is nothing less than a medical and therapeutic revolution."

Dr. Lev-Tov added that "This experience opens doors for us to treat a wide range of very serious illnesses such as PTSD, OCD, eating disorders, other addictions, severe depression, severe pain disorders, and I hope we will also be able to reach cognitive areas and treat attention deficit disorders, Alzheimer's, Parkinson's, and more."

Thanks to Slashdot reader Bruce66423 for sharing the article.
Space

SpaceX Plans To Build 'Starpipe' Natural Gas Pipeline To Fuel Starship Rockets (reuters.com) 49

SpaceX plans to begin building an eight-mile natural gas pipeline called "Starpipe" next month to supply its Starbase launch site with fuel for a much higher cadence of Starship launches. The pipeline is expected to enter service in January 2027. Reuters reports: The pipeline plan, previously reported by Rio Grande Valley Business Journal, signals Musk's intent to accelerate Starship's development and lay the groundwork for a faster flight rate. The 40-story rocket is central to SpaceX's push to expand its Starlink broadband network, deploy orbital AI data center satellites, and eventually carry astronauts to the moon and Mars.

Designed to be fully reusable, Starship uses about 630,000 gallons (2.4 million liters) of liquid methane per launch, currently delivered by hundreds of tanker trucks in an hours-long process incompatible with Musk's expansion plans. Starship has completed 12 test launches since 2023, but Musk aims to ramp up to dozens, hundreds and eventually thousands of launches a year.

Though it is unusual for a space company to build its own natural gas pipeline for launchpad fuel, Starpipe might only be an initial step in a longer-term plan for SpaceX, which has spent years exploring its own drilling operations near Starbase and throughout Texas, according to a Reuters review of Cameron County land records. SpaceX President Gwynne Shotwell told CNBC on June 12, when the company went public, that the company planned to build pipelines and process its own propellant, and was looking into drilling its own natural gas.

Space

Astronomers Find Biggest Super-Puff Planets Yet That Are Lighter Than Cotton Candy (apnews.com) 9

Astronomers have discovered two Jupiter-sized exoplanets with densities lower than cotton candy, making them the lightest known worlds of their size. The rare "super-puffs," located about 1,110 light-years away, are likely composed mostly of hydrogen and helium, with follow-up observations by the James Webb Space Telescope expected to probe their atmospheres. The Associated Press reports: [University of Oxford's George Dransfield] suspects these fluffy, wispy worlds are probably white or blue, depending on whether the skies there are cloudy -- no shades of cotton-candy pink. The planets are probably mostly hydrogen and helium, although it will take follow-up observations by NASA's Webb Space Telescope to confirm their chemical makeup.

Detected by NASA's Tess satellite over the past decade, these two especially puffy-puffs orbit a star in the southern constellation Volans, known as the flying fish. The researchers studied the planets' orbits using telescopes on Earth to determine their density, from 1,110 light-years away. A light-year is nearly 6 trillion miles (9.7 trillion kilometers). Jupiter, by comparison, is as much as 35 times denser than these two lightweights.

Considered rare in the cosmos, super-puffs are thought to form around the disk of gas and dust around a newborn star where there is more gas than dust. They shed much of the material over time, stripping down even more. NASA's tally of worlds outside our solar system currently stands at nearly 6,300 confirmed. Fewer than 40 are super-puffs, according to Dransfield.
The findings have been published in the journal Monthly Notices of the Royal Astronomical Society.
Space

'Fingerprints' of Black Hole's Event Horizon Detected For First Time (phys.org) 21

Researchers say they detected the first gravitational-wave "fingerprints" of a black hole's event horizon by analyzing the final moments of the powerful GW250114 merger. The findings support Einstein's general relativity and may eventually help probe frame dragging and quantum fluctuations near black holes. Phys.org reports: For the new research published in Nature, an international team of researchers analyzed data from the strongest gravitational wave ever recorded, known as GW250114, detected by the LIGO observatory in January 2025. By isolating the last burst of waves -- known as "direct waves" -- from this black hole merger, the scientists said they were able to extract information from closer to an event horizon than ever before. "This black hole horizon concept normally appears in science fiction," lead study author Sizheng Ma of the Perimeter Institute for Theoretical Physics in Canada told AFP. "But now we are really able to touch the region around the horizon with gravitational data," he added. "Sometimes I cannot believe this is really happening."

The last stage of two black holes merging is like a spoon stirring a glass of water, Ma explained. The resulting swirl in space creates the ripple of gravitational waves that travel at the speed of light in all directions. If the metaphorical spoon is stirring close enough to the black hole's event horizon, "this offers us a chance to decode the physics around that region," Ma said. By supporting the theory of general relativity, the results "proved that Einstein was correct again," he added.

The scientists emphasized that more research was needed to decipher what can be gleaned about event horizons using this method. But they did detect information about how black holes twist space around themselves as they rotate -- a phenomenon known as "frame dragging." "This is similar to pushing a glass into a table and twisting it, so that the tablecloth winds up around it," Maximiliano Isi, a gravitational wave astrophysicist at Columbia University, told AFP. In the future, the scientists hope to find signs of tiny changes known as quantum fluctuations. "In this way, we can really probe this near-horizon region to look for new physics," including searching for a deviation from general relativity, Ma said.

Mars

NASA Rover Detects Potential Signatures of Ancient Microbial Life On Mars (theguardian.com) 31

NASA's Perseverance rover has detected complex organic carbon in ancient Martian mudstones. The measurements were taken by the rover's Sherloc instrument and the organic carbon that was identified was from the Bright Angel outcrop, "a dried-up river that carried water into the planet's Jezero crater billions of years ago," notes The Guardian. From the report: The form of carbon detected, known as macromolecular carbon or MMC, can originate from living organisms. Geological processes can also produce the material, meaning its detection does not amount to proof of past Martian life. Dr Ashley Murphy at the Planetary Science Institute in Arizona said MMC can be found in different settings and types of rocks. "It may originate from biological sources such as fossilized organic matter found in microbial mats and coal," she said, but could also form in reactions between rocks and water or arrive on impacting meteorites.

The mudstone rocks from the Bright Angel outcrop caused a stir in 2024 when the Perseverance rover discovered intriguing surface spots and nodules that resemble features produced by fossilized microbes on Earth. When the scientific details were published last year, Sean Duffy, the former acting head of Nasa, said: "This very well could be the clearest sign of life that we've ever found on Mars." [...] The discovery means Nasa rovers have now found organic-bearing mudstones more than 2,000 miles apart on Mars. The others were reported by the Curiosity rover which is exploring the planet's Gale crater. It "indicates that the habitability of Mars, and the availability of organics, may have been widespread across the planet billions of years ago," the authors write in Science Advances.

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