hessian writes with a story at Wired (excerpt below) about a project from Drew Endy of the International Open Facility Advancing Biotechnology, or BIOFAB, to standardize a programming language connecting genetic information from DNA to the cell components that DNA can create. "The BIOFAB project is still in the early stages. Endy and the team are creating the most basic of building blocks — the 'grammar' for the language. Their latest achievement, recently reported in the journal Science, has been to create a way of controlling and amplifying the signals sent from the genome to the cell. Endy compares this process to an old fashioned telegraph. 'If you want to send a telegraph from San Francisco to Los Angeles, the signals would get degraded along the wire,' he says. "At some point, you have to have a relay system that would detect the signals before they completely went to noise and then amplify them back up to keep sending them along their way.""

Shipud writes "E.O. Wilson is the renowned father of sociobiology, a professor (emeritus) at Harvard, two time pulitzer prize winner, and a popularizer of science. In a recent article in the Wall Street Journal, Wilson provides controversial advice to aspiring young scientists. Wilson claims that math literacy is not essential, and that scientific models in biology, intuitively generated, can later be formalized by a specialized statistician. One blogger calls out Wilson on his article, arguing that knowing mathematics is essential to generating models, and that lacking what Darwin called the "extra sense" is essentially limiting to any scientist."

The Washington Post reports that concerns about high winds have postponed until tomorrow evening the launch of Orbital Science's Antares rocket from Wallops Island, Virginia. When the rocket finally launches, it should be a spectacular event for the region: "Clear skies should allow viewing of the 133-foot rocket throughout much of the Mid-Atlantic – including the Washington, D.C. area. Assuming technical issues don’t delay or abort the launch, look southeast and the rocket will be viewable about 10 degrees above the horizon in the Washington area at 5 p.m. 6:10 p.m."

alostpacket writes "The New York times reports that statistical scoring by the standardized testing company Pearson incorrectly disqualified over 4700 students from a chance to enter gifted / advanced programs in New York City schools. Only students who score in the 90th percentile or above are eligible for these programs. Those in the 97th or above are eligible for 5 of the best programs. 'According to Pearson, three mistakes were made. Students' ages, which are used to calculate their percentile ranking against students of similar age, were recorded in years and months, but should also have counted days to be precise. Incorrect scoring tables were used. And the formula used to combine the two test parts into one percentile ranking contained an error.' No mention of enlisting the help of the gifted children was made in the Times article, but it also contained a now-corrected error. This submission likely also contains an erro"

Florida today reports that cosmonaut Pavel Vinogradov on Friday became the oldest person to have completed a spacewalk. From the article: "Working outside the Russian side of the international outpost, Vinogradov and cosmonaut Roman Romanenko put in six hours and 38 minutes of high-flying maintenance work. They set up a plasma physics experiment and retrieved a package that exposed advanced spacecraft materials to the deleterious space environment. They also replaced a reflector that is part of an autonomous rendezvous and docking system that will guide a robotic European space freighter to the station in early June." NASASpaceFlight.com has more details on the spacewalk, as well as the note that Vinogradov edges out "Story Musgrave, who was 58 when he flew the Hubble SM-1 mission in 1993."

damn_registrars writes "The lobe-finned fish described as a 'living fossil' due to its apparent lack of change for hundreds of millions of years (thought to be extinct until the 1930s) has been sequenced by an international team, including scientists from Sweden, Harvard, and MIT. The 3-billion-base-pair genome of the Coelacanth was described yesterday in the journal Nature. This paper is published in an open (non-paywalled) manner on Nature, making the full text available to all. 'We found that the genes overall are evolving significantly slower than in every other fish and land vertebrate that we looked at.'"

sciencehabit writes "When Superstorm Sandy struck the United States on 30 October, it didn't just devastate the Eastern Seaboard, it shook the ground as far away as the West Coast, producing tiny vibrations in Earth's crust that were picked up by seismometers there. Scientists can use this activity to track the path of the storm. Now, they say that analyzing past records of these vibrations may help them discern whether climate change has influenced the amount of storminess over the world's oceans in recent decades."

ananyo writes "Researchers have tagged every single worker in entire colonies and used a computer to track them, accumulating what they say is the largest-ever data set on ant interactions. The biologists have found that the workers fall into three social groups that perform different roles: nursing the queen and young; cleaning the colony; and foraging for food. The insects, they found, tend to graduate from one group to another as they age. By creating heat maps to represent the workers’ positions, Mersch's team showed that nurses and foragers stick to their own company and seldom mix, even if the colony’s entrance and brood chamber are close together (abstract). Cleaners are more widely dispersed, patrolling the whole colony and interacting with both of the other groups. 'The ants can probably be in any place within their enclosures in less than a minute,' says Mersch, 'but even in these simple spaces, they organize into these spatial groups.'"

astroengine writes "About 1,200 light-years from Earth, five planets are circling around sun-like star Kepler-62, two of which are fortuitously positioned for water, if any exists, to remain liquid on their surfaces — a condition believed to be necessary for life. The discovery, made by scientists using NASA's planet-hunting Kepler space telescope, is the strongest evidence yet for more than one Earth-sized planet existing in a star's so-called 'habitable' zone. 'We're particularly delighted to find that there are two planets in the habitable zone,' lead Kepler scientist William Borucki, with NASA's Ames Research Center in California, told Discovery News. 'It sort of doubles our chances of finding that Earth we'd all like to find. When you think about Earth and Mars, if Mars had been a bit larger, if Jupiter hadn't been so close, we'd again have two planets in the habitable zone and maybe we'd have a place to go,' he said." There's also a third planet believed to be a good candidate for hosting water.

Famous for his work in math, astronomy, nuclear engineering, and theoretical physics, Freeman Dyson has left his mark on almost every scientific discipline. He's won countless awards, and written numerous books on a wide range of topics both scientific and philosophical. One of his biggest contributions to science was the unification of the three versions of quantum electrodynamics invented by Feynman, Schwinger and Tomonaga. 10 years after moving to the U.S. he started working on the Orion Project, which sought to create a spacecraft with a nuclear propulsion system. STNG exposed the idea of a Dyson sphere to the masses, and his hypothetical plan for making a comet habitable with the help of genetically-engineered plants is a personal favorite. Mr. Dyson has graciously agreed give us a bit of his time in order to answer your questions. As usual, ask as many as you'd like, but please, one question per post.

astroengine writes "World-renowned physicist Stephen Hawking has announced that he was likely wrong about his view that the Higgs boson doesn't exist — an outcome he doesn't find very exciting — conceding that he lost a $100 wager. Speaking at the Beckman Auditorium in Caltech, Pasadena, Calif., on Tuesday (April 16), the British physicist gave a public lecture on 'The Origins of the Universe,' summarizing new revelations in modern astrophysics and cosmology. After the lecture, Caltech physicist and colleague John Preskill commented on Hawking's fondness for placing bets when faced with conflicts of physics ideas. Hawking lost a famous wager to Preskill in 2004 in a debate over whether or not black holes destroy information (theory suggests they do not, opposing Hawking's argument). 'To love Stephen Hawking is to not always agree with Stephen Hawking,' Preskill quipped. 'He's usually right, but he's not always right. Sometimes we haven't been able to resolve our differences and we've resorted to making bets it's sad to say that although Stephen Hawking is without doubt a great scientist, he's a bad gambler.'"

olsmeister writes "Hydrogen Sulfide is a toxic, flammable, foul-smelling gas that some theorize may have been at least partially responsible for some of Earth's mass extinctions, including the Permian-Triassic event, which killed well over half of the species on the planet. Now, thanks to a fortuitous accident, doctoral student at the University of Washington seems to have discovered that very low doses of the gas seems to greatly enhance plant growth, causing plants to germinate more quickly and grow larger. The finding could have far reaching implications for both food and biofuel production."

An anonymous reader writes "This evening's planned launch of the Orbital Sciences Antares rocket had to be canceled just 12 minutes before liftoff, due to the unexpected separation of the booster's umbilical cable while the vehicle was on the launch pad. This is the first attempt to fly the Antares rocket, which is a commercial craft and direct competitor to the SpaceX Dragon 9. Beyond being the first flight of a brand new commercial rocket, this mission is also notable for carrying three of NASA's PhoneSats; small satellites powered by Android running on Nexus smartphones. With each PhoneSat costing just $3,500, they're designed to test the limits of extremely low cost spacecraft, similar to the European STRaND-1 mission. Since this is simply an orbital test, and the Antares will not be attempting to dock with the International Space Station, the launch window is highly flexible. It's anticipated Orbital Sciences will make another attempt at launching the Antares within 48 hours."

ananyo writes "Paul Steinhardt, an astrophysicist at Princeton University in New Jersey, and colleagues have posted a controversial paper on ArXiv arguing, based on the latest Higgs data and the cosmic microwave background map from the Planck mission, that the leading theory explaining the first moments of the Big Bang ('inflation') is fatally flawed. In short, Steinhardt says that the models that best fit the Planck data — known as 'plateau models' because their potential-energy profiles level off at relatively low energies — are far less likely to occur naturally than the models that Planck ruled out. Secondly, he says, the news for these plateau models gets dramatically worse when the results are analyzed in conjunction with the latest results about the Higgs field coming from CERN's Large Hadron Collider. Particle physicists working at the LHC have calculated that the Higgs field is likely to have started out in a high-energy, 'metastable' state rather than in a stable, low-energy configuration. Steinhardt likens the odds of the Higgs field initially being perched in the precarious metastable state as to those of dropping out of the sky over the Matterhorn and conveniently landing in a 'dimple near the top,' rather than crashing down to the mountain's base."

sciencehabit writes "Put a fruit fly larva in a spacelike vacuum, and the results aren't pretty. Within a matter of minutes, the animal will collapse into a crinkled, lifeless husk. Now, researchers have found a way to protect the bugs: Bombard them with electrons, which form a 'nano-suit' around their bodies. The advance could help scientists take high-resolution photographs of tiny living organisms. It also suggests a new way that creatures could survive the harsh conditions of outer space and may even lead to new space travel technology for humans." Work is also being done on electron "suits" that protect against radiation.

FIRST (For Inspiration and Recognition of Science and Technology) has robot competitions all over the United States. FIRST was founded by inventor Dean Kamen. According to Wikipedia he has said that the FIRST competition is the invention he is most proud of, and he predicts that the 1 million students who have taken part in the contests so far will be responsible for some significant technological advances in years to come. In any case, Robert Rozeboom (samzenpus) was at the Michigan FIRST championship with camcorder in hand, and brought back some great shots of robots at work -- or maybe play. They fired off volleys of Frisbee-like discs, ran into each other, and climbed metal pyramids, either independently or under the control of their human masters. There was a pretty good crowd in the stands, too, to cheer on the robots. Or more likely, to cheer on the robots' human masters, since we're not yet at the point where robot masters invite their robot friends to competitions where they show off their humans.

DoctorBit writes "MIT Technology Review is running a story about an arXiv paper in which geneticists Alexei A. Sharov and Richard Gordon propose that life as we know it originated 9.7 billion years ago. The researchers estimated the genetic complexity of phyla in the paleontological record by counting the number of non-redundant functional nucleotides in typical genomes of modern day descendants of each phylum. When plotting genetic complexity against time, the researchers found that genetic complexity increases exponentially, just as with Moore's law, but with a doubling rate of about once every 376 million years. Extrapolating backwards, the researchers estimate that life began about 4 billion years after the universe formed and evolved the first bacteria just before the Earth was formed. One might image that the supernova debris that formed the early solar system could have included bacteria-bearing chunks of rock from doomed planets circling supernova progenitor stars. If true, this retro-prediction has some interesting consequences in partly resolving the Fermi Paradox. Another interesting consequence for those attempting to recreate life's origins in a lab: bacteria may have evolved under conditions very different from those on earth."

ananyo writes with this bit about lab grown organs from Nature: "Scientists at Massachusetts General Hospital in Boston have fitted rats with kidneys that were grown in a lab from stripped-down kidney scaffolds. When transplanted, these 'bioengineered' organs starting filtering the rodents' blood and making urine. The team, led by organ-regeneration specialist Harald Ott, started with the kidneys of recently deceased rats and used detergent to strip away the cells, leaving behind the underlying scaffold of connective tissues such as the structural components of blood vessels. They then regenerated the organ by seeding this scaffold with two cell types: human umbilical-vein cells to line the blood vessels, and kidney cells from newborn rats to produce the other tissues that make up the organ (paper)."

ananyo writes "Sediment in a deep-sea core may hold radioactive iron spewed by a distant supernova 2.2 million years ago and preserved in the fossilized remains of iron-loving bacteria. If confirmed, the iron traces would be the first biological signature of a specific exploding star. Scientists have found the isotope iron-60, which does not form on Earth, in a sediment core from the eastern equatorial Pacific Ocean, dating to between about 1.7 million and 3.3 million years ago. The iron-60, which appears in layers dated to around 2.2 million years ago, could be the remains of magnetite chains formed by bacteria on the sea floor as radioactive supernova debris showered on them from the atmosphere, after crossing inter-stellar space at nearly the speed of light."

Knowledge Ecology International (KEI) director Jamie Love -- formally James Packard Love -- is the brain behind the "$1 a day" HIV drugs that have saved millions of lives in Africa and other poor parts of the world. Basically, he went around asking, "How much would it cost to make this HIV medication if the patent cost was removed?" At first, no one could answer. After a while, the answer came: Less than $1 a day. At that price, the Bush administration set up a massive program to deliver generic anti-HIV drugs to Africa. Jamie also works on copyright issues, boosts free software (he's a Linux user/evangelist and had more than a little to do with the Microsoft antitrust suit), and generally tries to make the international knowledge ecology more accessible and more useful for everyone, especially those who aren't rich. Or necessarily even prosperous. He's a smart guy (read the Wikipedia entry linked above), but more than that he's bullheaded. Jamie has worked on some of his initiatives for years, even decades. In many cases you can't say, "He hasn't succeeded," without adding "yet" on the end. (You'll understand that statement better after you watch the video, which we broke into two parts because it is far longer than our typical video interview.)