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Medicine

Human Mini-Brains Growing Inside Rat Bodies Are Starting To Integrate (inverse.com) 193

At the annual meeting of the Society for Neuroscience starting November 11 in Washington D.C., two teams of scientists plan to present previously unpublished research on the unexpected interaction between human mini-brains and their rat and mouse hosts. "In the new papers, according to STAT, scientists will report that the organoids survived for extended periods of time -- two months in one case -- and even connected to lab animals' circulatory and nervous systems, transferring blood and nerve signals between the host animal and the implanted human cells," reports Inverse. "This is an unprecedented advancement for mini-brain research." From the report: That mini-brains can even be grown in the lab is a huge advancement in the first place, as they have many of the same characteristics as living human brains that are in the early stages of development. Though they're not "alive" in the same sense that you and I are, they grow and are organized into different layers like our brains are. They even react in similar ways to stimuli like psychedelic drugs. Organoids are poised to revolutionize research on the human brain since scientists can perform tests on them that would be unethical to attempt on living humans. STAT also reports that a third lab, in addition to the two presenting at the Society for Neuroscience meeting, has successfully connected human brain organoids to blood vessels. This attempt veered into such challenging ethical territory, though, that the lab reportedly paused its efforts.
Science

Cities Are Scolding Countries at UN Climate Conference To Cut Emissions (vice.com) 159

A reader shares a report: An alliance of major cities including New York, Toronto, and London challenged nation states attending the United Nations climate talks in Bonn, Germany this week "to kick dirty carbon to the curb" and immediately "commit and work straightaway towards carbon neutrality, 100 percent renewable energy, zero-waste and zero-carbon." The Carbon Neutral Cities Alliance is a new collaboration of 20 international cities (other members include Washington DC, San Francisco, Oslo, and Sydney). All are striving for carbon neutrality and cutting greenhouse gas emissions by at least 80 percent by 2050. "Dirty fuels and climate disruption are killing and displacing millions of citizens around the world," the Alliance stated in a strongly-worded letter sent to every country's delegation at climate talks, known as COP 23. "Cities are on the frontline of climate impacts. We see the urgency of climate action and need nation-states to be as committed as we are," Johanna Partin, the director of the Alliance and former advisor to the mayor of San Francisco, told Motherboard by phone.
Science

Indian Capital Declares Emergency as Toxic Smog Thickens By the Hour (reuters.com) 129

New Delhi, the Indian capital declared a pollution emergency on Thursday as toxic smog hung over the city for a third day and air quality worsened by the hour. From a report: Illegal crop burning in the farm states surrounding New Delhi, vehicle exhaust emissions in a city with limited public transport and swirling construction dust have caused the crisis, which arises every year. The problem has been compounded this year by still conditions, the weather office said. A U.S. embassy measure of tiny particulate matter PM 2.5 showed a reading of 608 at 10 a.m. when the safe limit is 25. An hour before it was 591.
NASA

NASA: We're Not Building Flying Taxi Software For Uber (theregister.co.uk) 24

News outlets reported on Wednesday that Uber had signed a contract with NASA to develop software for the ride-hailing company's autonomous "flying taxis." A day later, the space agency has clarified its involvement in the project and the specifics of the contract. From the report: Uber's chief product officer Jeff Holden spoke at the Web Summit in Lisbon yesterday where he was promoting the fledgling autonomous taxi project, revealed last year, Uber Elevate. And of course he never claimed that NASA was working on software for his firm, merely explaining that it had inked an agreement to work with the public body on the latter's air traffic control project. Uber told us that while NASA was not "committing funding or anything like that", it said "having their decades of aeronautic experience actively collaborating with our engineers is a huge help for tackling the aviation traffic management hurdles." A NASA spokesperson, meanwhile, told us Uber had indeed signed what it described as a "generic Space Act Agreement" for participation in the programme back in January, joining a "multitude" of others. The project and its members are "researching prototype technologies for a UAS Traffic Management (UTM) system that could develop airspace integration requirements for enabling safe, efficient low-altitude operations," according to NASA's website. So no new news on the software front.

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