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Medicine

Scientists Save Child's Life By Growing Him New Skin (scientificamerican.com) 107

An anonymous reader quotes a report from Scientific American: The German doctors realized they had to do something drastic or their seven-year-old patient would die. The boy had escaped war-ravaged Syria with his parents, and a rare genetic disease had left him with raw, blistering sores over 80 percent of his body. His doctors in a children's burn unit tried everything they could to treat his illness, called junctional epidermolysis bullosa -- even grafting some skin from his father to see if it would heal the child's wounds. But his body rejected this. Finally, they e-mailed Michele De Luca, a researcher in Italy, to ask for help.

The doctors took a small sample of skin from one of the few places on the boy's body where it was not flaming red or flaking off, and sent it to De Luca. His team at the center used a virus to insert into the skin cells a correct copy of a gene called LAMB3; the boy's own defective copy had caused his epidermolysis bullosa. De Luca and his colleagues grew the skin cells over scaffolds in their lab to form large sheets, the way doctors often do for burn patients. In two surgeries in October and November 2015, the Italian and German teams covered the boy's limbs, sides and back with these sheets of fresh skin. After being too sick even to get out of bed before his surgeries, "he was standing up already by Christmas," De Luca says. In January 2016 the boy, whose name is not being released to protect his privacy, received a few more skin patches -- and in February he was released from the University Hospitals of the Ruhr University Bochum in Germany.

Space

SpaceX Rocket Engine Explodes During Test (space.com) 115

According to The Washington Post, a SpaceX rocket engine exploded Sunday (Nov. 5) at the company's test facility in McGregor, Texas. The explosion reportedly occurred during a "qualification test" of a Merlin engine, the type that powers SpaceX's workhorse Falcon 9 rocket. Space.com reports: SpaceX has suspended engine testing while it investigates what caused the incident, which didn't injure anyone, the Post added. In a statement provided to the Post, SpaceX representatives said they didn't expect the explosion to affect the company's launch schedule. That schedule has been pretty packed this year. SpaceX has already launched 16 missions, all of them successful, in 2017 -- twice as many as its previous high in a calendar year. And all but three of these missions also involved landings of the Falcon 9 first stage, for eventual refurbishment and reuse.
NASA

NASA Is Working With Uber on Its Flying Taxi Project 51

Ride-hailing service Uber on Wednesday took a step forward in its plan to make autonomous "flying taxis" a reality, signing a contract with NASA to develop the software to manage them. From a report: Uber said at the Web Summit tech conference in Lisbon that it signed a Space Act Agreement with NASA for the development of "unmanned traffic management." This is NASA's push to figure out how unmanned aerial systems (UAS), such as drones that fly at a low altitude, can operate safely. Uber wants to make vertical take-off and landing vehicles. That will allow their flying cars to take off and land vertically. They will fly at a low altitude. This is the start-up's first partnership with a U.S. federal government agency. NASA is also working with other companies to develop traffic management for these low altitude vehicles. "UberAir will be performing far more flights on a daily basis than it has ever been done before. Doing this safely and efficiently is going to require a foundational change in airspace management technologies," Jeff Holden, chief product officer at Uber, said in a statement on Wednesday. "Combining Uber's software engineering expertise with NASA's decades of airspace experience to tackle this is a crucial step forward for Uber Elevate."
NASA

NASA Astronaut Dick Gordon, Pilot of Gemini and Apollo 12, Dies At 88 (astronautscholarship.org) 58

sconeu writes: Dick Gordon, pilot of Gemini 11 and command module pilot of Apollo 12, has died at the age of 88. Gordon was also slated to command the cancelled Apollo 18 mission. "Dick Gordon is an American hero, and a true renaissance man by any measure. He was an American naval officer and aviator, chemist, test pilot, NASA astronaut, professional football executive, oil and gas executive and generous contributor to worthy causes," said Curt Brown, board chairman of the Orlando-based Astronaut Scholarship Foundation and an astronaut and veteran of six space flights. "He was in a category all his own." The Astronaut Scholarship Foundation has a touching write-up that details Gordon's childhood and career successes. You can read the full article here.
Biotech

EPA Approves Release of Bacteria-Carrying Mosquitoes To 20 States (nature.com) 133

schwit1 writes: The U.S. Environmental Protection Agency (EPA) has approved the use of a common bacterium to kill wild mosquitoes that transmit viruses such as dengue, yellow fever and Zika, Nature's news team has learned. On November 3rd, the agency told biotechnology start-up MosquitoMate that it could release the bacterium Wolbachia pipientis into the environment as a tool against the Asian tiger mosquito (Aedes albopictus). Lab-reared mosquitoes will deliver the bacterium to wild mosquito populations. The decision -- which the EPA has not formally announced -- allows the company, which is based in Lexington, Kentucky, to release the bacteria-infected mosquitoes in 20 U.S. states and Washington DC.

MosquitoMate will rear the Wolbachia-infected A. albopictus mosquitoes in its laboratories, and then sort males from females. Then the laboratory males, which don't bite, will be released at treatment sites. When these males mate with wild females, which do not carry the same strain of Wolbachia, the resulting fertilized eggs don't hatch because the paternal chromosomes do not form properly. The company says that over time, as more of the Wolbachia-infected males are released and breed with the wild partners, the pest population of A. albopictus mosquitoes dwindles. Other insects, including other species of mosquito, are not harmed by the practice, says Stephen Dobson, an entomologist at the University of Kentucky in Lexington and founder of MosquitoMate.

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