New submitter Big Nemo '60 writes with news that the National Institute of Mental Health is seeking to modernize the diagnosis of mental illness through the use of neuroscience, genetics, etc. From the article: "The world's biggest mental health research institute is abandoning the new version of psychiatry's 'bible' — the Diagnostic and Statistical Manual of Mental Disorders — questioning its validity and stating that 'patients with mental disorders deserve better.' This bombshell comes just weeks before the publication of the fifth revision of the manual, called DSM-5." More importantly, they are going to be shifting funding to research projects that seek to define new categories of mental illness using modern medical science, ignoring the current DSM categorizations: "The strength of each of the editions of DSM has been 'reliability' .. The weakness is its lack of validity. Unlike our definitions of ischemic heart disease, lymphoma, or AIDS, the DSM diagnoses are based on a consensus about clusters of clinical symptoms, not any objective laboratory measure. In the rest of medicine, this would be equivalent to creating diagnostic systems based on the nature of chest pain or the quality of fever. ... NIMH has launched the Research Domain Criteria (RDoC) project to transform diagnosis by incorporating genetics, imaging, cognitive science, and other levels of information to lay the foundation for a new classification system. ... It became immediately clear that we cannot design a system based on biomarkers or cognitive performance because we lack the data. In this sense, RDoC is a framework for collecting the data needed for a new nosology. But it is critical to realize that we cannot succeed if we use DSM categories as the 'gold standard.' ... Imagine deciding that EKGs were not useful because many patients with chest pain did not have EKG changes. That is what we have been doing for decades when we reject a biomarker because it does not detect a DSM category. We need to begin collecting the genetic, imaging, physiologic, and cognitive data to see how all the data — not just the symptoms — cluster and how these clusters relate to treatment response."

vinces99 writes "Imagine taking a swab of saliva from your mouth and, within minutes, having your DNA ready for genome sequencing. A new device from University of Washington engineers and a company called NanoFacture can extract human DNA from fluid samples in a simpler, more efficient and environmentally friendly way than conventional methods. It will give hospitals and labs a much easier way to separate DNA from human fluid samples, which will help with genome sequencing, disease diagnosis and forensic investigations."

HiveBio in Seattle is not the world's first community-based biology lab, but it may be the first one started by a high school student. Her name is Katriona Guthrie-Honea, and her co-founder is Bergen McMurray. They managed to get a lot of equipment and supplies donated to their new venture, along with a successful Microryza Campaign that raised $6425 even though their target was only $5100. They're renting space from a local hackerlab, and getting an insane amount of publicity for a venture that's just starting out. But why not? If Bergen's and Katriona's example can spur others to learn and create, whether in mechanical engineering, physics, electronics, computer science or biology, it's all good -- not only for the participants, but for anyone who might someday benefit from creations or discoveries made by people who got their first taste of hands-on science or engineering in a hackerspace or community biology lab.

Okian Warrior writes "New Hampshire based RR Auction is selling the EKG of Neil Armstrong's heartbeat taken when he stepped onto the moon, among many other items of space and aviation historical interest. 'It was really slow on the way down, while Aldrin's was racing' described Gerald Schaber, geologist, who had the task of monitoring Armstrong's heartbeat during the final famous moments of the Apollo 11 landing. The auction begins May 16th."

Zothecula writes "Instead of traipsing through Florida in search of the Fountain of Youth, Spanish explorer Juan Ponce de León might have been better off turning his search inwards. More specifically, he should have turned his attention to a region of the brain called the hypothalamus. At least that's what research carried out on mice by scientists at New York's Albert Einstein College of Medicine of Yeshiva University suggests. They found that the hypothalamus controls many aspects of aging, opening up the potential to slow down the aging process by altering signal pathways within that part of the brain."

cylonlover writes "Aside from the inconvenience of injecting insulin multiple times a day, type 1 diabetics also face health risks if the dosage level isn't accurate. A new approach developed by U.S. researchers has the potential to overcome both of these problems. The method relies on a network of nanoscale particles that, once injected into the body, can maintain normal blood sugar levels for more than a week by releasing insulin when blood-sugar levels rise."

Guppy writes "Does Tylenol reduce existential distress? Acetaminophen (Paracetamol) has been used to relieve mild-to-moderate physical pain for over a century, yet its actual mechanism of action continues to be debated; modern research has demonstrated an intriguing connection with the body's endocannabinoid system, raising the question of whether it may also have subtle psychological effects as well. A recent paper claims Acetaminophen can alter our response to existential challenge; previous findings have suggested that it may blunt the pain of social rejection as well."