Science

The Biggest Problem With Lab-Grown Chicken Is Growing the Chicken (bloomberg.com) 74

Ten years ago, a Dutch scientist unveiled a $330,000 lab-grown hamburger made from cow cells grown in petri dishes. It took six weeks to culture the patty. A chef cooked it onstage as journalists watched. Reactions ranged from "unpleasant" to "beeflike." The scientist expected supermarket sales in a decade. His company and others have since raised over $2 billion but have little to show, only recently making one pound of chicken monthly. Despite bold promises of mass production, low emissions, and better nutrition, commercial viability remains elusive. Bloomberg Business: The company [Upside Foods], in a letter from its attorney to Bloomberg Businessweek, says plans for scaling up have been an evolution saddled with "realities and complexities of doing something that has never been done before. Innovation rarely happens in a straight and continuous line."

The dream is moist, meaty flesh self-multiplying ad infinitum in high-tech, stainless steel cell-growing chambers. But according to internal company documentation and eight former employees, most of whom requested anonymity because they don't have permission to discuss confidential information, Upside at the moment is actually growing just minuscule numbers of chicken skin-type cells in small plastic bottles, then scraping them out gram by gram to compress and mold them into a single forkful of flesh. This labor-intensive chicken has higher levels of cholesterol and lead than the real thing, publicly available company documentation shows. Even if that sounds remotely desirable, some scientists say the whole energy-intensive endeavor may actually be worse for the environment, especially with chicken, which has the smallest carbon footprint of anything at the local butcher. All of which points to this question: Why exactly are we chasing lab-grown chicken?[...]

Earth

Stop Planting Trees, Says Guy Who Inspired World to Plant a Trillion Trees (wired.com) 155

In a cavernous theater lit up with the green shapes of camels and palms at COP28 in Dubai, ecologist Thomas Crowther, former chief scientific adviser for the United Nations' Trillion Trees Campaign, was doing something he never would have expected a few years ago: begging environmental ministers to stop planting so many trees. From a report: Mass plantations are not the environmental solution they're purported to be, Crowther argued when he took the floor on December 9 for one of the summit's "Nature Day" events. The potential of newly created forests to draw down carbon is often overstated. They can be harmful to biodiversity. Above all, they are really damaging when used, as they often are, as avoidance offsets-- "as an excuse to avoid cutting emissions," Crowther said.

The popularity of planting new trees is a problem -- at least partly -- of Crowther's own making. In 2019, his lab at ETH Zurich found that the Earth had room for an additional 1.2 trillion trees, which, the lab's research suggested, could suck down as much as two-thirds of the carbon that humans have historically emitted into the atmosphere. "This highlights global tree restoration as our most effective climate change solution to date," the study said. Crowther subsequently gave dozens of interviews to that effect. This seemingly easy climate solution sparked a tree-planting craze by companies and leaders eager to burnish their green credentials without actually cutting their emissions, from Shell to Donald Trump. It also provoked a squall of criticism from scientists, who argued that the Crowther study had vastly overestimated the land suitable for forest restoration and the amount of carbon it could draw down. (The study authors later corrected the paper to say tree restoration was only "one of the most effective" solutions, and could suck down at most one-third of the atmospheric carbon, with large uncertainties.)

Crowther, who says his message was misinterpreted, put out a more nuanced paper last month, which shows that preserving existing forests can have a greater climate impact than planting trees. He then brought the results to COP28 to "kill greenwashing" of the kind that his previous study seemed to encourage -- that is, using unreliable evidence on the benefits of planting trees as an excuse to keep on emitting carbon. "Killing greenwashing doesn't mean stop investing in nature," he says. "It means doing it right. It means distributing wealth to the Indigenous populations and farmers and communities who are living with biodiversity."

Space

Jeff Bezos Says Blue Origin Needs To Be 'Much Faster' 127

In an interview with Lex Fridman, Jeff Bezos candidly acknowledged Blue Origin's slow progress (compared to SpaceX). From a report: "Blue Origin needs to be much faster, and it's one of the reasons that I left my role as the CEO of Amazon a couple of years ago," he said. "I wanted to come in, and Blue Origin needs me right now. Adding some energy, some sense of urgency. We need to move much faster. And we're going to."

How is Blue Origin going to speed up?

"We're going to become the world's most decisive company across any industry," he said. "We're going to get really good at taking appropriate technology risks, making those decisions quickly. You know, being bold on those things. And having the right culture that supports that. You need people to be ambitious, technically ambitious. If there are five ways to do something, we'll study them, but let's go through them very quickly and make a decision. We can always change our mind."
Medicine

Scientists Pinpoint Cause of Morning Sickness To Hormone Made By Fetus 145

Scientists have pinpointed the cause of nausea and vomiting in pregnancy, "finding that the severity of illness is influenced by how much of a hormone called GDF15 the growing fetus makes," reports Science Magazine. The findings have been published in the journal Nature. From the report: GDF15 is present in the blood of nonpregnant people and is known to be associated with nausea; it's also been tested as a weight loss aid because of its tendency to suppress appetite. Levels of the hormone rise sharply in early pregnancy and increase throughout gestation. Pregnant people with higher GDF15 concentrations have been documented as having a higher risk of vomiting and nausea. Some researchers suggest the hormone-caused aversion to some smells and tastes might encourage an expectant parent to avoid foods potentially dangerous to the fetus.

To find out more about GDF15 changes during pregnancy, University of Cambridge physician-scientist Stephen O'Rahilly and colleagues studied half a dozen pregnant people who were known from previous genetic screening to produce a slightly different version of the GDF15 protein from their fetuses. Researchers could take advantage of that difference to trace whether GDF15 in the parent's blood originated in the parental or fetal genome: Almost all of it came from the fetus, O'Rahilly says. The team also took a closer look at the link between GDF15 levels and pregnancy sickness. Consistent with previous research, questionnaires from more than 300 participants showed that people who reported vomiting and nausea had significantly higher levels of circulating GDF15 on average than people without these symptoms. The researchers also found elevated levels of GDF15 in an analysis of more than 50 women hospitalized with hyperemesis gravidarum.

Still, hormone levels alone couldn't explain the difference in sickness severity. "There was a big overlap" in GDF15 levels between the groups, O'Rahilly says. He and co-author Marlena Fejzo, a researcher at the University of Southern California, suspected that people's sensitivity to GDF15 might also play a role. (Fejzo began to study the condition after her own pregnancy loss following hyperemesis gravidarum.) To test the idea, the researchers studied 10 nonpregnant people with a rare genetic variant known to carry a heightened risk of hyperemesis gravidarum. These people had reduced GDF15 levels in their blood, hinting that naturally low levels of the hormone might predispose someone to sickness during pregnancy. The researchers found the opposite when they asked 20 pregnant people with beta thalassemia, a blood disorder associated with high GDF15 levels, about their pregnancy symptoms: Just 5% of this group reported nausea or vomiting. O'Rahilly's lab found a similar pattern in animal experiments.
Communications

NASA's Voyager 1 Probe In Interstellar Space Can't Phone Home (space.com) 34

NASA's Voyager 1 spacecraft is, once again, having trouble transmitting any scientific or systems data back to Earth. "The 46-year-old spacecraft is capable of receiving commands, but a problem seems to have arisen with the probe's computers," reports Space.com. Slashdot readers quonset and ArchieBunker shared the news. From the report: Voyager 1's flight data system (FDS), which collects onboard engineering information and data from the spacecraft's scientific instruments, is no longer communicating as expected with the probe's telecommunications unit (TMU), according to a NASA blog post on Dec. 12. When functioning properly, the FDS compiles the spacecraft's info into a data package, which is then transmitted back to Earth using the TMU. Lately, that data package has been "stuck," the blog post said, "transmitting a repeating pattern of ones and zeros." Voyager's engineering team traced the problem back to the FDS, but it could be weeks before a solution is found. In May 2022, Voyager 1 experienced transmitting issues for several months before a workaround was found. Meanwhile, Voyager 2 experienced an unplanned "communications pause" earlier this year after a routine sequence of commands triggered a 2-degree change in the spacecraft's antenna orientation. This prevented it from receiving commands or transmitting data back to Earth until NASA fixed the issue a week later.

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