Science

Human Brain Cells Hooked Up To a Chip Can Do Speech Recognition (technologyreview.com) 56

An anonymous reader quotes a report from MIT Technology Review: Brain organoids, clumps of human brain cells grown in a dish, can be hooked up to an electronic chip and carry out simple computational tasks, a new study shows. Feng Guo and his team at Indiana University Bloomington generated a brain organoid from stem cells, attached it to a computer chip, and connected their setup, known as Brainoware, to an AI tool. They found that this hybrid system could process, learn, and remember information. It was even able to carry out some rudimentary speech recognition. The work, published today in Nature Electronics, could one day lead to new kinds of bio-computers that are more efficient than conventional computers.

"This is a first demonstration of using brain organoids [for computing]," says Guo. "It's exciting to see the possibilities of organoids for biocomputing in the future." With Brainoware, Guo aimed to use actual brain cells to send and receive information. When the researchers applied electrical stimulation to the hybrid system they'd built, Brainoware responded to those signals, and changes occurred in its neural networks. According to the researchers, this result suggests that the hybrid system did process information, and could perhaps even perform computing tasks without supervision. Guo and his colleagues then attempted to see if Brainoware could perform any useful tasks. In one test, they used Brainoware to try to solve mathematical equations. They also gave it a benchmark test for speech recognition, using 240 audio clips of eight people pronouncing Japanese vowels. The clips were converted into electrical signals and applied to the Brainoware system. This generated signals in the neural networks of the brain organoid, which were then fed into an AI tool for decoding.

The researchers found that the brain organoid -- AI system could decode the signals from the audio recordings, which is a form of speech recognition, says Guo. "But the accuracy was low," he says. Although the system improved with training, reaching an accuracy of about 78%, it was still less accurate than artificial neural networks, according to the study. Lena Smirnova, an assistant professor of public health at Johns Hopkins University, points out that brain organoids do not have the ability to truly hear speech but simply exhibit "a reaction" to pulses of electrical stimulation from the audio clips. And the study did not demonstrate whether Brainoware can process and store information over the long term or learn multiple tasks. Generating brain cell cultures in a lab and maintaining them long enough to perform computations is also a huge undertaking. Still, she adds, "it's a really good demonstration that shows the capabilities of brain organoids."

Medicine

Every Homeopathic Eye Drop Should Be Pulled Off the Market, FDA Says 177

An anonymous reader shares a report: This year has been marked by many terrifying things, but perhaps the most surprising of the 2023 horrors was ... eye drops. The seemingly innocuous teeny squeeze bottle made for alarming headlines numerous times during our current revolution around the sun, with lengthy lists of recalls, startling factory inspections, and ghastly reports of people developing near-untreatable bacterial infections, losing their eyes and vision, and dying.

Recapping this unexpected threat to health, the Food and Drug Administration on Tuesday released an advisory titled "What You Should Know about Eye Drops" in hopes of keeping the dangers of this year from leaking into the next. Among the notable points from the regulator was this stark pronouncement: No one should ever use any homeopathic ophthalmic products, and every single such product should be pulled off the market. The point is unexpected, given that none of the high-profile infections and recalls this year involved homeopathic products. But, it should be welcomed by any advocates of evidence-based medicine.
Space

Scientists Discover Nuclear Fission Amongst the Stars (space.com) 31

For the first time, scientists have discovered nuclear fission occurring amongst the stars, supporting the idea that neutron stars create "superheavy" elements when they collide, which then break down via nuclear fission to birth rare elements. Space.com reports: Nuclear fission is basically the opposite of nuclear fusion. While nuclear fusion refers to the smashing of lighter elements to create heavier elements, nuclear fission is a process that sees energy released when heavy elements split apart to create lighter elements. Nuclear fission is pretty well known, too. It's actually the basis of energy-generating nuclear power plants here on Earth -- however, it had not been seen occurring amongst the stars before now.

The team of researchers led by North Carolina State University scientist Ian Roederer searched data concerning a wide range of elements in stars to discover the first evidence that nuclear fission could therefore be acting when neutron stars merge. These findings could help solve the mystery of where the universe's heavy elements come from. Scientists know that nuclear fusion is not just the primary source of energy for stars, but also the force that forges a variety of elements, the "heaviest" being iron.

The evidence of nuclear fission discovered by [Matthew Mumpower, research co-author and a scientist at Los Alamos National Laboratory] and the team comes in the form of a correlation between "light precision metals," like silver, and "rare earth nuclei," like europium, showing in some stars. When one of these groups of elements goes up, the corresponding elements in the other group also increases, the scientists saw. The team's research also indicates that elements with atomic masses -- counts of protons and neutrons in an atomic nucleus -- greater than 260 may exist around neutron star smashes, even if this existence is brief. This is much heavier than many of the elements at the "heavy end" of the periodic table.
"The only plausible way this can arise among different stars is if there is a consistent process operating during the formation of the heavy elements," Mumpower said. "This is incredibly profound and is the first evidence of fission operating in the cosmos, confirming a theory we proposed several years ago."

"As we've acquired more observations, the cosmos is saying, 'hey, there's a signature here, and it can only come from fission.'"

The research was published in the journal Science.

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