California is in the process of approving new guidelines for math education in public schools that "pushes Algebra 1 back to 9th grade, de-emphasizes calculus, and applies social justice principles to math lessons," writes Joe Hong via the San Francisco Standard. The new approach would have been approved earlier this month but has been delayed due to the attention and controversy it has received. Here's an excerpt from the report: When Rebecca Pariso agreed to join a team of educators tasked in late 2019 with California's new mathematics framework, she said she expected some controversy. But she didn't expect her work would be in the national spotlight. [...] Every eight years (PDF), a group of educators comes together to update the state's math curriculum framework. This particular update has attracted extra attention, and controversy, because of perceived changes it makes to how "gifted" students progress -- and because it pushes Algebra 1 back to 9th grade, de-emphasizes calculus, and applies social justice principles to math lessons. San Francisco pioneered key aspects of the new approach, opting in 2014 to delay algebra instruction until 9th grade and to push advanced mathematics courses until at least after 10th grade as a means of promoting equity.

San Francisco Unified School District touted the effort as a success, asserting that algebra failure rates fell and the number of students taking advanced math rose as a result of the change. The California Department of Education cited those results in drafting the statewide framework. But critics have accused the district of using cherry-picked and misleading assertions to bolster the case for the changes. The intent of the state mathematics framework, its designers say, is to maintain rigor while also helping remedy California's achievement gaps for Black, Latino and low-income students, which remain some of the largest in the nation. At the heart of the wrangling lies a broad agreement about at least one thing: The way California public schools teach math isn't working. On national standardized tests, California ranks in the bottom quartile among all states and U.S. territories for 8th grade math scores.

Yet for all the sound and fury, the proposed framework, about 800-pages long, is little more than a set of suggestions. Its designers are revising it now and will subject it to 60 more days of public review. Once it's approved in July, districts may adopt as much or as little of the framework as they choose -- and can disregard it completely without any penalty. "It's not mandated that you use the framework," said framework team member Dianne Wilson, a program specialist at Elk Grove Unified. "There's a concern that it will be implemented unequally."

Not a single scientist has applied to a UK government visa scheme for Nobel prize laureates and other award winners since its launch six months ago, New Scientist reported Tuesday. From a report: The scheme has come under criticism from scientists and has been described as "a joke." In May, the government launched a fast-track visa route for award-winners in the fields of science, engineering, the humanities and medicine who want to work in the UK. This prestigious prize route makes it easier for some academics to apply for a Global Talent visa -- it requires only one application, with no need to meet conditions such as a grant from the UK Research and Innovation funding body or a job offer at a UK organisation.

The number of prizes that qualify academics for this route currently stands at over 70, and includes the Turing Award, the L'Oreal-UNESCO for Women in Science International Awards, and various gongs awarded by professional or membership bodies both in the UK and elsewhere. "Winners of these awards have reached the pinnacle of their career and they have so much to offer the UK," said home secretary Priti Patel when the prestigious prize scheme launched in May. "This is exactly what our new point-based immigration system was designed for -- attracting the best and brightest based on the skills and talent they have, not where they've come from." But a freedom of information request by New Scientist has revealed that in the six months since the scheme was launched, no one working in science, engineering, the humanities or medicine has actually applied for a visa through this route.

A short update on the projected launch date of the $10 billion James Webb Space Telescope came out of NASA on Monday, and it wasn't exactly a heart-warming missive. From a report: The large, space-based telescope's "no earlier than" launch date will slip from December 18 to at least December 22 after an "incident" occurred during processing operations at the launch site in Kourou, French Guiana. That is where the telescope will launch on an Ariane 5 rocket provided by the European Space Agency. "Technicians were preparing to attach Webb to the launch vehicle adapter, which is used to integrate the observatory with the upper stage of the Ariane 5 rocket," NASA said in a blog post. "A sudden, unplanned release of a clamp band -- which secures Webb to the launch vehicle adapter -- caused a vibration throughout the observatory."

Hmmmmmm shares a report from SciTechDaily: Investigators from Brigham and Women's Hospital and MIT used the power of nanotechnology to discover a new way that cancer can disarm its would-be cellular attackers by extending out nanoscale tentacles that can reach into an immune cell and pull out its powerpack. Slurping out the immune cell's mitochondria powers up the cancer cell and depletes the immune cell. The new findings, published in Nature Nanotechnology, could lead to new targets for developing the next generation of immunotherapy against cancer.

To investigate how cancer cells and immune cells interact at the nanoscale level, [corresponding author Shiladitya Sengupta, PhD, and co-director of the Brigham's Center for Engineered Therapeutics] and colleagues set up experiments in which they co-cultured breast cancer cells and immune cells, such as T cells. Using field-emission scanning electron microscopy, they caught a glimpse of something unusual: Cancer cells and immune cells appeared to be physically connected by tiny tendrils, with widths mostly in the 100-1000 nanometer range. (For comparison, a human hair is approximately 80,000 to 100,000 nanometers). In some cases, the nanotubes came together to form thicker tubes. The team then stained mitochondria -- which provide energy for cells -- from the T cells with a fluorescent dye and watched as bright green mitochondria were pulled out of the immune cells, through the nanotubes, and into the cancer cells.

"By carefully preserving the cell culture condition and observing intracellular structures, we saw these delicate nanotubes and they were stealing the immune cells' energy source," said co-corresponding author Hae Lin Jang, PhD, a principal investigator in the Center for Engineered Therapeutics. "It was very exciting because this kind of behavior had never been observed before in cancer cells. This was a tough project as the nanotubes are fragile and we had to handle the cells very gently to not break them." The researchers then looked to see what would happen if they prevented the cancer cells from hijacking mitochondria. When they injected an inhibitor of nanotube formation into mouse models used for studying lung cancer and breast cancer, they saw a significant reduction in tumor growth.