According to Politico, "Biden allied groups, including the Democratic National Committee, are [...] planning to engage fact-checkers more aggressively and work with SMS carriers to dispel misinformation about vaccines that is sent over social media and text messages." The White House is also planning to work with social media platforms and traditional media outlets to combat misinformation and ultimately improve vaccination rates. TmoNews reports: The White House could ask carriers like T-Mobile, Verizon, and AT&T to step in and stop the spread of these text messages. This is one way they hope they will be able to get their vaccination message across better and eliminate misinterpretation. There is no word yet on whether or not the White House has reached out to these carriers to help them screen anti-vax messages. But if it does, it will be interesting to see how this will be acted upon and which tools would be used. Then again, it could open a can of worms with potential issues that would violate customer privacy and an individual's right to free speech. "We are steadfastly committed to keeping politics out of the effort to get every American vaccinated so that we can save lives and help our economy further recover," White House spokesperson Kevin Munoz said. "When we see deliberate efforts to spread misinformation, we view that as an impediment to the country's public health and will not shy away from calling that out."

The molecules produced by stomach bacteria could give the human body a helping hand when it comes to the immune system, even going so far as to help fight tumors. ScienceAlert reports: "The results are an example of how metabolites of intestinal bacteria can change the metabolism and gene regulation of our cells and thus positively influence the efficiency of tumor therapies," says immunologist Maik Luu from University Hospital Wurzburg in Germany. Short chain fatty acids (SCFAs) are one of the helpful molecules produced when dietary fiber is fermented in the gut. Major SCFAs are acetate and butyrate, along with the less common pentanoate, found only in some bacteria. All of these SCFAs have a bunch of positive health effects in humans, such as the regulation of insulin resistance, cholesterol, and even appetite. Luu and colleagues have now found that butyrate and pentanoate also boost the anti-tumor activity of a type of killer T cell known as CD8, by reprogramming the way they work. For the first time, they have experimentally demonstrated this in mice.

Using lab mice, the team found that certain commensal bacteria produce pentanoate. For example, one relatively rare human gut bacterium, Megasphaera massiliensis, enhanced small proteins called cytokines in the killer T cells, leading to an increased ability to destroy tumor cells. As a control, the team experimented with other, non-pentanoate producing bacteria and found no effect on the cytokine levels. This finding could be particularly useful for therapies that leverage the immune system to fight cancer. Some tumor cells have proteins on their surfaces that can bind to proteins on T cells, resulting in an immune 'checkpoint' response which tells the killer cell to spare its target -- in this case, the cancer cell. Immune checkpoint inhibitor (ICI) therapy works by blocking these checkpoint proteins, allowing the T cells to do their job and destroy the tumor cells. [...] The team also looked at a genetically modified type of T cell called CAR-T cells which are used in immunotherapy, and found that the bacterial assistance worked the same way, particularly on solid tumors. The research has been published in Nature Communications.