Medicine

Tantalizing But Preliminary Evidence of a 'Brain Microbiome' (sciencemag.org) 65

An anonymous reader quotes a report from Science Magazine: We know the menagerie of microbes in the gut has powerful effects on our health. Could some of these same bacteria be making a home in our brains? A poster presented here this week at the annual meeting of the Society for Neuroscience drew attention with high-resolution microscope images of bacteria apparently penetrating and inhabiting the cells of healthy human brains. The work is preliminary, and its authors are careful to note that their tissue samples, collected from cadavers, could have been contaminated. But to many passersby in the exhibit hall, the possibility that bacteria could directly influence processes in the brain -- including, perhaps, the course of neurological disease -- was exhilarating.

Talking hoarsely above the din of the exhibit hall on Tuesday evening, neuroanatomist Rosalinda Roberts of The University of Alabama in Birmingham (UAB), told attendees about a tentative finding that, if true, suggests an unexpectedly intimate relationship between microbes and the brain. Her lab looks for differences between healthy people and those with schizophrenia by examining slices of brain tissue preserved in the hours after death. About 5 years ago, neuroscientist Courtney Walker, then an undergraduate in Roberts's lab, became fascinated by unidentified rod-shaped objects that showed up in finely detailed images of these slices, captured with an electron microscope. Roberts had seen the shapes before. "But I just dismissed them, because I was looking for something else," she says. "I would say 'Oh, here are those things again.'" But Walker was persistent, and Roberts started to consult colleagues at UAB. This year, a bacteriologist gave her unexpected news: They were bacteria. Her team has now found bacteria somewhere in every brain they've checked -- 34 in all -- about half of them healthy, and half from people with schizophrenia.

Google

Google Is Absorbing DeepMind's Health Care Unit To Create An 'AI Assistant For Nurses and Doctors' 27

Google has announced that it's absorbing DeepMind Health, a part of its London-based AI lab DeepMind. "In a blog post, DeepMind's founders said it was a 'major milestone' for the company that would help turn its Streams app -- which it developed to help the UK's National Health Service (NHS) -- into 'an AI-powered assistant for nurses and doctors' that combines 'the best algorithms with intuitive design,'" reports The Verge. "Currently, the Streams app is being piloted in the UK as a way to help health care practitioners manage patients." From the report: DeepMind says its Streams team will remain in London and that it's committed to carrying out ongoing work with the NHS. These include a number of ambitious research projects, such as using AI to spot eye disease in routine scans. The news is potentially controversial given the upset in the UK caused by one of DeepMind's early deals with the NHS. The country's data watchdogs ruled in 2017 that a partnership DeepMind struck with the NHS was illegal, as individuals hadn't been properly informed about how their medical data would be used.

Another consistent worry for privacy advocates in the UK has been the prospect of Google getting its hands on this sort of information. It's not clear what the absorption of the Streams team into Google means in that context, but we've reached out to DeepMind for clarification. According to a report from CNBC, the independent review board DeepMind set up to oversee its health work will likely be shut down as a result of the move. More broadly speaking, the news clearly signals Google's ambitions in health care and its desire to get the most of its acquisition of the London AI lab. There have reportedly been long-standing tensions between DeepMind and Google, with the latter wanting to commercialize the former's work. Compared to Google, DeepMind has positioned itself as a cerebral home for long-sighted research, attracting some of the world's best AI talent in the process.
Movies

Douglas Rain, Voice of HAL 9000 In '2001: A Space Odyssey,' Dies At 90 (hollywoodreporter.com) 53

schwit1 shares a report from The Hollywood Reporter: Douglas Rain, the veteran Canadian stage actor who provided the soft and gentle voice of the rogue HAL 9000 computer for Stanley Kubrick's classic 2001: A Space Odyssey and its sequel, has died. He was 90. The first drafts of the 2001 script had HAL being voiced by a woman and was called Athena; afterward, it was decided that the computer should sound more like a man. Nigel Davenport, Martin Balsam and others were tried out -- and ruled out -- before and during filming of the 1968 sci-fi thriller.

"Well, we had some difficulty deciding exactly what HAL should sound like, and Marty just sounded a little bit too colloquially American, whereas Rain had the kind of bland mid-Atlantic accent we felt was right for the part,' Kubrick told Newsday film critic Joseph Gelmis in an interview for the 1970 book The Film Director as Superstar. Kubrick told Rain that he had made the computer "too emotional and too human." So, in late 1967, the actor flew to New York City and spent a day and a half -- about 9 1/2 hours in all -- to voice HAL. As reported on the blog 2010: The Year We Make Contact, Rain "did the recordings with his bare feet resting on a pillow, in order to maintain the required relaxed tone."

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