Medicine

Man Reports PillCam Stuck In His Gut For Over 12 Weeks 183

A Portland man appears to have a pill-sized camera stuck in his gut. That man is me... Let me explain.

For the average Joe, the following statement might sound a bit peculiar: I have swallowed a pill-sized camera a number of times. You see, I have Crohn's Disease (CD) in the small intestine -- a 20 foot-long portion of the gastrointestinal tract that runs between the stomach and the large intestine (colon). A "PillCam" is the most non-invasive, detailed method to survey this area as it doesn't require a scope up the rectum or down the esophagus, nor does it require any tissue slicing. It's also one of the safest procedures available -- the retention rate is as low as 1%. Unfortunately, this most recent capsule endoscopy resulted in my admission to the 1% club.

On March 27th, 2018, I swallowed the PillCam that is currently lodged in my small intestine. If you do the math, that's more than 82 days ago (over 12 weeks). After hiking Smith Rock and summiting Black Butte a couple weeks later, I thought for sure the pill would have exited. It didn't, as evident by the follow-up X-ray. It can be difficult to find research on such a what-if scenario that happens to so few, but I did manage to find a Motherboard article telling the story of Scott Willis, a CD patient that had a PillCam lodged in his gut for eight weeks. One of the key differences between him and me is that he had a partial block and endured more symptoms, prompting him to schedule a procedure to get it out quicker. I'm relatively symptom free.

We have tried upping the dose of corticosteroids to reduce inflammation and help the pill pass through the strictured areas, but that didn't seem to work. Most recently, I had two double-balloon enteroscopy procedures done within a week apart. They were able to locate the PillCam during the second procedure, but weren't able to retrieve it without risking the scope itself becoming stuck. The next step is to try again via the esophagus. The potential issue/complication here is the location. As my doctors warned, the PillCam is stuck 15 feet down and the scope is only 20 feet in length. There's little wiggle room if the pill is slightly further down the GI tract than estimated.

I am sharing this story with the Slashdot community for two reasons. First, those entrenched in the world of cyborgs and/or modern-day medical procedures may find this experience particularly interesting. Second, the more people who know about the procedures and complications of Crohn's Disease the better. For those interested, I'll update this post after the next procedure. Have you or someone you know experienced a capsule endoscopy? Please share what you feel comfortable with.

UPDATE 7/11/18: Yesterday, I had the procedure to remove the PillCam via the esophagus and it wasn't successful. The doctor said he tried everything he could to retrieve it but the scope wasn't quite long enough to reach the pill. I'll be talking with a surgeon next week and will update this post when a surgery date is confirmed.
Businesses

Studies Find Evidence That Meditation Is Demotivating (nytimes.com) 163

An anonymous reader shares an excerpt from a report written by behavioral scientists Kathleen D. Vohs and Andrew C. Hafenbrack: The practical payoff of mindfulness [meditation] is backed by dozens of studies linking it to job satisfaction, rational thinking and emotional resilience. But on the face of it, mindfulness might seem counterproductive in a workplace setting. To test this hunch, we recently conducted five studies, involving hundreds of people, to see whether there was a tension between mindfulness and motivation. As we report in a forthcoming article in the journal Organizational Behavior and Human Decision Processes, we found strong evidence that meditation is demotivating.

Some of the participants in our studies were trained in a few of the most common mindfulness meditation techniques. They were instructed by a professional meditation coach to focus on their breathing or mentally scan their bodies for physical sensations, being gently reminded throughout that there was no right or wrong way to do the exercise. Other participants were led through a different exercise. Some were encouraged to let their thoughts wander; some were instructed to read the news or write about recent activities they had done. Then we gave everyone a task to do. Among those who had meditated, motivation levels were lower on average. Those people didn't feel as much like working on the assignments, nor did they want to spend as much time or effort to complete them. Meditation was correlated with reduced thoughts about the future and greater feelings of calm and serenity -- states seemingly not conducive to wanting to tackle a work project.
The studies also found that meditation "neither benefited nor detracted from a participant's quality of work." Furthermore, Vohs and Hafenbrack found that a financial bonus for outstanding performance did not overcome the demotivating effect of mindfulness. "While the promise of material rewards will always be a useful tool for motivating employees, it is no substitute for internal motivation," the report reads.
Crime

Was the Stanford Prison Experiment a Sham? (nypost.com) 136

Frosty Piss writes: The Stanford Prison Experiment was conducted in 1971 by psychology professor Philip Zimbardo using college students to investigate the psychological effects of perceived power by focusing on the struggle between prisoners and prison officers. In the study, volunteers were randomly assigned to be either "guards" or "prisoners" in a mock prison, with Zimbardo serving as the superintendent. The results seemed to show that the students quickly embraced their assigned roles, with some guards enforcing authoritarian measures and ultimately subjecting some prisoners to psychological torture, while many of the prisoners passively accepted psychological abuse and, by the officers' request, actively harassed other prisoners who tried to stop it. After Berkeley graduate Douglas Korpi appeared to have a nervous breakdown while playing the role of an inmate, the experiment was shut down. There's just one problem: Korpi's breakdown was a sham. Dr. Ben Blum took to Medium to publish his claims. "Blum's expose -- based on previously unpublished recordings of Zimbardo, a Stanford psychology professor, and interviews with the participants -- offers evidence that the 'guards' were coached to be cruel," reports New York Post. "One of the men who acted as an inmate told Blum he enjoyed the experiment because he knew the guards couldn't actually hurt him."

"There were no repercussions. We knew [the guards] couldn't hurt us, they couldn't hit us. They were white college kids just like us, so it was a very safe situation," said Douglas Korpi, who was 22-years-old when he acted as an inmate in the study. The Berkeley grad now admits the whole thing was fake. Zimbardo also "admitted that he was an active participant in the study, meaning he had influence over the results," reports New York Post. According to an audio recording from the Stanford archive, you can hear Zimbardo encouraging the guards to act "tough."
Software

Machine Figures Out Rubik's Cube Without Human Assistance (technologyreview.com) 86

An anonymous reader quotes a report from MIT Technology Review: [Stephen McAleer and colleagues from the University of California, Irvine] have pioneered a new kind of deep-learning technique, called "autodidactic iteration," that can teach itself to solve a Rubik's Cube with no human assistance. The trick that McAleer and co have mastered is to find a way for the machine to create its own system of rewards. Here's how it works. Given an unsolved cube, the machine must decide whether a specific move is an improvement on the existing configuration. To do this, it must be able to evaluate the move. Autodidactic iteration does this by starting with the finished cube and working backwards to find a configuration that is similar to the proposed move. This process is not perfect, but deep learning helps the system figure out which moves are generally better than others. Having been trained, the network then uses a standard search tree to hunt for suggested moves for each configuration.

The result is an algorithm that performs remarkably well. "Our algorithm is able to solve 100% of randomly scrambled cubes while achieving a median solve length of 30 moves -- less than or equal to solvers that employ human domain knowledge," say McAleer and co. That's interesting because it has implications for a variety of other tasks that deep learning has struggled with, including puzzles like Sokoban, games like Montezuma's Revenge, and problems like prime number factorization.
The paper on the algorithm -- called DeepCube -- is available on Arxiv.
Space

NASA's Most Experienced Astronaut Retires, Spent 665 Days In Space (upi.com) 49

An anonymous reader quotes UPI: After nearly four decades with NASA, including 22 years as an astronaut, Peggy Whitson is leaving the space agency. Her retirement is effective Friday, NASA announced... Whitson ends her career with multiple records to her name, including most time spent in space by a U.S. astronaut -- 665 days...

The 57-year-old Whitson was a scientist before she was an astronaut, earning graduate degrees in biochemistry from Rice University in Houston before coming to conduct research at NASA's Johnson Space Center in 1989. The NASA scientist began training as an astronaut in 1996. She made her first trip to the International Space Station in 2008. During her time in space, including three long-duration stints aboard International Space Station, she helped carry out 21 science investigation and became the agency's first space station science officer... Whitson took a second turn as commander during Expedition 51, part of her most recent -- and last -- stay on the space station, which spanned from November 2016 to September 2017.

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