An anonymous reader quotes a report from Ars Technica: Over the nine or so years that Mylan, Inc. has been selling -- and hiking the price -- of EpiPens, the drug company has been misclassifying the life-saving device and stiffing Medicaid out of full rebate payments, federal regulators told Ars. Under the Medicaid Drug Rebate Program, drug manufacturers, such as Mylan, can get their products covered by Medicaid if they agree to offer rebates to the government to offset costs. With a brand-name drug such as the EpiPen, which currently has no generic versions and has patent protection, Mylan was supposed to classify the drug as a "single source," or brand name drug. That would mean Mylan is required to offer Medicaid a rebate of 23.1 percent of the costs, plus an "inflation rebate" any time Mylan raises the price of the brand-name drug at a rate higher than inflation. Mylan has opted for such price increases -- a lot. Since Mylan bought the rights to EpiPen in 2007, it has raised the price on 15 separate occasions, bringing the current list price to $608 for a two-pack up from about $50 a pen in 2007. That's an increase of more than 500 percent, which easily beats inflation. But instead of classifying EpiPen as a "single source" drug, Mylan told regulators that it's a "non-innovator multiple source," or generic drug. Under that classification, Mylan is only required to offer a rebate of 13 percent and no inflation rebates. It's unclear how much money Mylan has skipped out on paying in total to state and federal governments. But according to the state health department of Minnesota, as reported by CNBC, the misclassification cost that state $4.3 million this year alone.

sciencehabit quotes a report from Science Magazine: If you shatter a bone in the future, a 3D printer and some special ink could be your best medicine. Researchers have created what they call "hyperelastic bone" that can be manufactured on demand and works almost as well as the real thing, at least in monkeys and rats. Though not ready to be implanted in humans, bioengineers are optimistic that the material could be a much-needed leap forward in quickly mending injuries ranging from bones wracked by cancer to broken skulls. Researchers at Northwestern University, Evanston, in Illinois are working on a hyperelastic bone, which is a type of scaffold made up of hydroxyapatite, a naturally occurring mineral that exists in our bones and teeth, and a biocompatible polymer called polycaprolactone, and a solvent. Hydroxyapatite provides strength and offers chemical cues to stem cells to create bone. The polycaprolactone polymer adds flexibility, and the solvent sticks the 3D-printed layers together as it evaporates during printing. The mixture is blended into an ink that is dispensed by the printer, layer by layer, into exact shapes matching the bone that needs to be replaced. The idea is, a patient would come in with a nasty broken bone -- say, a shattered jaw -- and instead of going through painful autograft surgeries or waiting for a custom scaffold to be manufactured, he or she could be x-rayed and a 3D-printed hyperelastic bone scaffold could be printed that same day.

Jamie Fullerton, reporting for Motherboard:Daan Roosegaarde reached into the pocket of his suit jacket, pulled out a plastic bag filled with black powder, and waved it around. "This is Beijing smog," Roosegaarde said, before gesturing to the seven-metre tall, gently humming metal tower we are stood next to in the Chinese capital's art district, 798. "We collected it from the tower yesterday. Incredibly disgusting." Dutch designer Roosegaarde's smog souvenir may be disgusting, but it's the byproduct of an invention that he has touted as a potential alleviator of China's pollution problems. His "smog-free tower" sucks air, filters it with ion technology, with Roosegaarde having explained: "By charging the Smog Free Tower with a small positive current, an electrode will send positive ions into the air. These ions will attach themselves to fine dust particles. A negatively charged surface -- the counter electrode -- will then draw the positive ions in, together with the fine dust particles. The fine dust "is collected together with the ions and stored inside of the tower." With the dust collected, the tower then spews out cleaner air through vents, creating a "bubble" in the area surrounding it that contains, according to Roosegaarde, up to 70 percent fewer pollution particles than the pre-cleaned air.

sciencehabit writes from a report via Science Magazine: All good things must come to an end, and so it will be tomorrow when the Rosetta spacecraft makes its planned soft landing onto the surface of comet 67P/Churyumov-Gerasimenko, the culmination of 2 years of close-up studies. Solar power has waned as 67P's orbit takes it and Rosetta farther from the sun, and so the mission team decided to go on a last data-gathering descent before the lights go out. This last data grab is a bonus after a mission that is already changing theorists' views about how comets and planets arose early in the solar system. Several Rosetta observations suggest that comets form not from jolting mergers of larger cometesimals, meters to kilometers across, but rather from the gentle coalescence of clouds of pebbles. And the detection of a single, feather-light, millimeter-sized particle -- preserved since the birth of the solar system -- should further the view of a quiet birth. The report concludes: "A slew of instruments will keep gathering data as Rosetta approaches the surface at the speed of a gentle stroll. For team members whose instruments have already been turned off to conserve power, the ending is bittersweet -- but their work is far from over. Most instrument teams have only examined their own data, and are just now thinking about combining data sets. "We've just started collaborating with other teams," [Holger Sierks of the Max Planck Institute for Solar System Research in Gottingen, Germany, chief of Rosetta's main camera,] says. "This is the beginning of the story, not the end."