Inhaling polluted air increases the risk of type 2 diabetes, the first study of its kind in India has found. Research conducted in Delhi and the southern city of Chennai found that inhaling air with high amounts of PM2.5 particles led to high blood sugar levels and increased type 2 diabetes incidence. From a report: When inhaled, PM2.5 particles -- which are 30 times thinner than a strand of hair -- can enter the bloodstream and cause several respiratory and cardiovascular diseases. The study [PDF] is part of ongoing research into chronic diseases in India that began in 2010. It is the first to focus on the link between exposure to ambient PM2.5 and type 2 diabetes in India, one of the worst countries in the world for air pollution. The average annual PM2.5 levels in Delhi was 82-100ug/m3 and in Chennai was 30-40ug/m3, according to the study, many times the WHO limits of 5ug/m3. Indiaâ(TM)s national air quality standards are 40ug/m3.

There is also a high burden of non-communicable diseases, including diabetes, hypertension and heart disease in India; 11.4% of the population -- 101 million people -- are living with diabetes, and about 136 million are pre-diabetic, according to a paper published in the Lancet in June. The average diabetes prevalence in the European Union was 6.2% in 2019, and 8.6% in the UK in 2016. The Lancet study found India's diabetes prevalence to be higher than previous estimations and showed a higher number of diabetics in urban than rural India.

An anonymous reader quotes a report from NPR: Peru's Kimberly Garcia set a world record in her gold-medal winning turn at the women's 20 kilometer race walk event at the Pan American Games this weekend. Until she didn't. Once the race was over, organizers determined there was a serious "measuring problem" with the track, making the race times of Garcia, fellow medal winners Glenda Morejon of Ecuador and Peru's Evelyn Inga, and their competitors null and void. The athletes guessed the track had been drawn up roughly 3 kilometers (about 1.9 miles) shorter than it was supposed to be. Garcia crossed the finish line in 1 hour, 12 minutes and 26 seconds. The world record of 1 hour, 23 minutes and 49 seconds is held by China's Jiayu Yang. The athletes suspected something was amiss mid-race, according to the Associated Press.

The Santiago 2023 Corporation, the group in charge of the 2023 Pan American Games, placed the blame on the Pan American Athletics Association, which reportedly chose the person who measured the race course. In a statement following the race, Santiago 2023 said the official who measured the course "did not take accurate measurements of the route the athletes took during the race." The group continued, "We deeply regret the inconvenience for the athletes, their coaches, the public and the attending press, but this situation cannot be attributed to the Organizing Committee."

An anonymous reader quotes a report from The Guardian: They say you catch more flies with honey than vinegar. But when it comes to tackling a tricky task, researchers have found that getting angry can also be a powerful motivator. The experiments suggest people who are angry perform better on a set of challenging tasks than those who are emotionally neutral. "These findings demonstrate that anger increases effort toward attaining a desired goal, frequently resulting in greater success," said Dr Heather Lench, the first author of the study.

The study, published in the Journal of Personality and Social Psychology (PDF), details how researchers at Texas A&M University conducted experiments involving more than 1,000 people, and analyzed survey data from more than 1,400 people, to explore the possible impact of anger on people in various circumstances. In one experiment, students were shown images previously found to elicit anger, desire, amusement, sadness or no particular emotion at all. Participants were subsequently asked to solve a series of anagrams. The results reveal that for a challenging set of anagrams, those who were angry did better than those in the other possible emotional states -- although no difference was seen for easy anagrams.

The researchers say one explanation could be down to a link between anger and greater persistence, with the team finding those who were angry spent more time on the difficult set of anagrams. In another experiment, participants who were angry did better at dodging flags in a skiing video game than those who were neutral or sad, and were on a par with those who felt amusement or desire. "This pattern could indicate that general physical arousal had a benefit for game scores, as this would be greater in anger, amused, and desire conditions compared to the sad and neutral conditions," the researchers write. However, no such differences in performance was found when it came to an easier video game.

The group behind the radical open-access initiative Plan S has announced its next big plan to shake up research publishing -- and this one could be bolder than the first. From a report: It wants all versions of an article and its associated peer-review reports to be published openly from the outset, without authors paying any fees, and for authors, rather than publishers, to decide when and where to first publish their work. The group of influential funding agencies, called cOAlition S, has over the past five years already caused upheaval in the scholarly publishing world by pressuring more journals to allow immediate open-access publishing. Its new proposal, prepared by a working group of publishing specialists and released on 31 October, puts forward an even broader transformation in the dissemination of research.

It outlines a future "community-based" and "scholar-led" open-research communication system in which publishers are no longer gatekeepers that reject submitted work or determine first publication dates. Instead, authors would decide when and where to publish the initial accounts of their findings, both before and after peer review. Publishers would become service providers, paid to conduct processes such as copy-editing, typesetting and handling manuscript submissions.

[...] If the vision comes to pass, it would mark a revolution in science publishing. Each element has already been endorsed and trialled on a small scale. But as a whole, the proposal "is describing a system that is completely different from today's mainstream forms of scholarly communication," says Andrea Chiarelli, a consultant at Research Consulting in Nottingham, UK. cOAlition S is launching a six-month process, co-led by Research Consulting, to collect feedback from members of the global research community on whether the plan will meet their needs.

Around 66 million years ago, the Chicxulub asteroid caused a mass extinction event, killing three-quarters of life on Earth, including the dinosaurs. A new study suggests that fine silicate dust from the asteroid, which remained in the atmosphere for up to 15 years, played a more significant role in causing the impact winter and extinction than previously thought. Phys.Org reports: Fine silicate dust from pulverized rock would have stayed in the atmosphere for 15 years, dropping global temperatures by up to 15 degrees Celsius, researchers said in a study in the journal Nature Geoscience. [...] For the study, the international team of researchers was able to measure dust particles thought to be from right after the asteroid struck. The particles were found at the Tanis fossil site in the US state of North Dakota.

Though 3,000 kilometers (1,865 miles) away from the crater, the site has preserved a number of remarkable finds believed to be dated from directly after the asteroid impact in sediment layers of an ancient lake. The dust particles were around 0.8 to 8.0 -- micrometers -- just the right size to stick around in the atmosphere for up to 15 years, the researchers said.

Entering this data into climate models similar to those used for current-day Earth, the researchers determined that dust likely played a far greater role in the mass extinction than had previously been thought. Out of all the material that was shot into the atmosphere by the asteroid, they estimated that it was 75 percent dust, 24 percent sulfur and one percent soot. The dust particles "totally shut down photosynthesis" in plants for at least a year, causing a "catastrophic collapse" of life, [said Ozgur Karatekin, a researcher at the Royal Observatory of Belgium].

An anonymous reader quotes a report from Bloomberg: GSK will pay 23andMe $20 million for access to the genetic-testing company's vast trove of consumer DNA data, extending a five-year collaboration that's allowed the drugmaker to mine genetic data as it researches new medications. Under the new agreement, 23andMe will provide GSK with one year of access to anonymized DNA data from the approximately 80% of gene-testing customers who have agreed to share their information for research, 23andMe said in a statement Monday. The genetic-testing company will also provide data-analysis services to GSK.

23andMe is best known for its DNA-testing kits that give customers ancestry and health information. But the DNA it collects is also valuable, including for scientific research. With information from more than 14 million customers, the only data sets that rival the size of the 23andMe library belong to Ancestry.com and the Chinese government. The idea for drugmakers is to comb the data for hints about genetic pathways that might be at the root of disease, which could significantly speed up the long, slow process of drug development. GSK and 23andMe have already taken one potential medication to clinical trials: a cancer drug that works to block CD96, a protein that helps modulate the body's immune responses. It entered that testing phase in four years, compared to an industry average of about seven years. Overall, the partnership between GSK and 23andMe has produced more than 50 new drug targets, according to the statement.

The new agreement changes some components of the collaboration. Any discoveries GSK makes with the 23andMe data will now be solely owned by the British pharmaceutical giant, while the genetic-testing company will be eligible for royalties on some projects. In the past, the two companies pursued new drug targets jointly. GSK's new deal with 23andMe is also non-exclusive, leaving the genetic-testing company free to license its database to other drugmakers.

The Food and Drug Administration is warning consumers to ditch 26 over-the-counter eye drop products found at big retailers -- including CVS, Rite Aid, and Target -- due to a risk of infection. Consumers should not buy any of the products and should immediately stop using them if they've already purchased them. From a report: The products include Target's branded Up & Up Dry Eye Relief Lubricant Eye Drops and Up & Up Extreme Relief Dry Eye, as well as Lubricant Eye Drops and Lubricant Gel Drops branded by CVS Health and Rite Aid. The warning also includes eye drop products branded as Rugby and Leader (both from Cardinal Health) and Velocity Pharma. A full list can be found here, as can links to report adverse events.

In an advisory posted Friday, the FDA reported that no infections or adverse events have been linked to the products so far. But the agency said it "found insanitary conditions in the manufacturing facility and positive bacterial test results from environmental sampling of critical drug production areas in the facility."

An anonymous reader shares a report: PFAS stands for "per- and polyfluoroalkyl substances," a family of upwards of 15,000 or more human-made and incredibly durable chemical compounds that have been used in countless industrial and consumer applications for decades. Firefighting foams, waterproof hiking boots, raincoats, nonstick frying pans, dental floss, lipstick, and even the ink used to label packaging -- all can contain PFAS. The compounds are ubiquitous in drinking water and soil, even migrating to Arctic sea ice. PFAS are called forever chemicals because once present in the environment, they do not degrade or break down. They accumulate, are transferred throughout the watershed, and ultimately persist. The quest to reduce the amount of PFAS in the environment is what led me to an industrial park in a southern suburb of Grand Rapids, Michigan. The jar of PFAS concentrate in my hand is part of a demonstration arranged by my hosts, Revive Environmental, during a tour of the company's PFAS destruction site, one of the first in the country to operate commercially and at scale. A few yards in front of me sits the company's PFAS "Annihilator" in a white shipping container.

The Annihilator represents just one of several technologies now vying to break down and destroy PFAS. These span the gamut from established processes like electrochemical oxidation and supercritical water oxidation to emerging techniques relying on ultraviolet light, plasma, ultrasound, or catalyst-driven thermal processes. Some are deployed in field tests. Other companies are actively running pilot programs, many with various divisions of the US Department of Defense and other government agencies. And many other technologies are still undergoing laboratory research. There's good reason for this. Not only are PFAS everywhere around us; they're also in us. Humans can't break down PFAS, and our bodies struggle to clear them from our systems. Studies suggest they're in my blood and yours -- the majority of Americans,' in fact -- and they have been linked to increased risks of kidney and testicular cancer, decreased infant birthweights, and high blood pressure. And that's only what we know about now: researchers continue to grapple with the full impacts of PFAS on human and environmental health.

Wikipedia defines LIGO as "a large-scale physics experiment and observatory designed to detect cosmic gravitational waves." (It stands for Laser Interferometer Gravitational-Wave Observatory — that is, measuring the interference caused by superimposed waves.)

Now Science Alert reports: A technique for squeezing light in the arms of LIGO's interferometer has allowed its measurements to cross the quantum barrier.

For LIGO, it's a bold new realm of sensitivity, giving the gravitational wave detector the ability to find 60% more dead star mergers than the rate of its previous run, which was around one or two detections every week or so... "Now that we have surpassed this quantum limit, we can do a lot more astronomy," says physicist Lee McCuller of Caltech...

LIGO's sensitivity was already absolutely jaw-dropping. The interferometer works by detecting ripples in space-time that are generated by colliding black holes and neutron stars, millions of billions to light-years away. These cause gravitational waves, like ripples in a pond. We can't feel them; but they can be detected in miniscule deviations in the path of light down a long, long tunnel. These deviations are incredibly small, down to trillions of times smaller than a human hair. But once you get into subatomic scales — the quantum realm — LIGO's abilities are hobbled. That's because, on those unimaginably small scales, particles randomly pop in and out of space, creating a constant background hiss of quantum noise that's louder than any signal.

Frequency-dependent squeezing is a way of amplifying the signals to be 'louder' than the quantum noise... If you pinch a property of light, such as amplitude (or power), other properties, such as frequency, can be measured more accurately... [T]he light can be squeezed in multiple ways to amplify the frequency of the gravitational waves the scientists are looking for... "We've known for a while how to write down the equations to make this work, but it was not clear that we could actually make it work until now. It's like science fiction," says physicist Rana Adhikari of Caltech...

This means we're likely to see a significant uptick in the number of black hole and neutron star collisions we observe out there in the wider Universe.

Are face masks effective in stopping virus transmissions? CBS News re-visited the question Sunday on its news show 60 Minutes by sending their chief medical correspondent to interview Linsey Marr, a professor who specializes in aerosol science at Virginia Tech University.

Here's a transcript from an excerpt posted on YouTube: 60 Minutes: Is there any doubt in your mind that masks prevent the person who's wearing it from getting Covid — or at least, are helpful?

Professor Marr: I would say they are very helpful in reducing the chances that the person will get Covid. Because it's reducing the amount of virus that you would inhale from the air around you.

It's not going to guarantee that it's going to protect you, because are masks are not 100% effective — we talk about N-95's being 95% efficient at filtering out particles, if they're properly fitted and everything, and so that's in an ideal world. But even so, if you — instead of breathing in 100 virsues, I'm breathing in 20, because my mask was 80% effective? That's a huge reduction, and that greatly reduces the chance that I'm going to become infected.
On the CBS News web site, they highlight this excerpt from the interview: Early in the pandemic, some guidance from health professionals suggested that wearing a mask might actually lead to infection: A person might encounter a contaminated mask and then touch their eyes, nose, or mouth. But research in the ensuing years has shown that fear to be misplaced. "There wasn't any evidence really that that happens," Marr said.

Marr said her team aerosolized the coronavirus, pulled it through a mask, and then examined how much virus survived on the mask. The study reported some viral particle remained on some cloth masks, but no virus survived on the N95s or surgical masks. Marr's team also touched artificial skin to masks and looked at how many virus particles transferred to the artificial skin. No infectious virus transferred.

"I hope the study kind of shows that it's something we don't need to worry about as much as we were told," Marr said.
CBS gave their video interview the headline "Face mask effectiveness: What we know now" — and asked professor Marr for a definitive answer: 60 Minutes: There was a lot of controversy over whether or not masks worked at all. Were you able to show that they worked scientifically?

Professor Marr: We were able to show that they block particles that are the same size as those that carry the virus... What happens is the virus is being carried in the air, and it's not just going straight through those holes. It has to weave around all these layers of fibers in there. As the air is going around the curves, the virus may crash into one of those fibers, and so then it's trapped, or maybe it comes up close to the fiber and brushes against it. And the really small particles, like the virus by itself if it were by itself, would be small enough that it undergoes these random motions, because it's getting bounced around by the gas molecules, and it ends up crashing into the fibers of the mask too.

So there was accumulating evidence — and there had been kind of a handful of papers before that, too, showing the same thing. That masks — even cloth masks — do something.

"Scientists recently fired up the world's smallest particle accelerator for the first time," reports Space.com.

"The tiny technological triumph, which is around the size of a small coin, could open the door to a wide range of applications, including using the teensy particle accelerators inside human patients." The new machine, known as a nanophotonic electron accelerator (NEA), consists of a small microchip that houses an even smaller vacuum tube made up of thousands of individual "pillars." Researchers can accelerate electrons by firing mini laser beams at these pillars. The main acceleration tube is approximately 0.02 inches (0.5 millimeter) long, which is 54 million times shorter than the 16.8-mile-long (27 kilometers) ring that makes up CERN's Large Hadron Collider (LHC) in Switzerland — the world's largest and most powerful particle accelerator... The inside of the tiny tunnel is only around 225 nanometers wide. For context, human hairs are 80,000 to 100,000 nanometers thick, according to the National Nanotechnology Institute.

In a new study, published Oct. 18 in the journal Nature, researchers from the Friedrich-Alexander University of Erlangen-Nuremberg (FAU) in Germany used the tiny contraption to accelerate electrons from an energy value of 28.4âkiloelectron volts to 40.7âkeV, which is an increase of around 43%. It is the first time that a nanophotonic electron accelerator, which was first proposed in 2015, has been successfully fired, the researchers wrote in a statement...

"For the first time, we really can speak about a particle accelerator on a [micro]chip," study co-author Roy Shiloh, a physicist at FAU, said in the statement.
What they accomplished "was demonstrated almost simultaneously by colleagues at Stanford University," according to the researchers' statement. "Their results are currently under review, but can be viewed on a repository. The two teams are working together on the realization of the 'Accelerator on a chip' in a project funded by the Gordon and Betty Moore Foundation" in 2015.

A new study found that adult ADHD "may take a toll on the brain and is linked to a higher likelihood of developing dementia," reports the Washington Post: A study published in JAMA Network Open reported that being diagnosed with ADHD as an adult is associated with a 2.77-fold increased risk of dementia.

The study only showed an association and doesn't tell us whether ADHD is a direct cause of cognitive decline. But the results suggest that "if you do have attention-deficit disorder, you're going to have more trouble with normal brain aging," said Sandra Black, a cognitive neurologist at Sunnybrook Research Institute in Toronto who was not involved in the study. "It adds another risk factor...."

Notably, of the 730 participants with adult ADHD, 13.2 percent (96 participants) were diagnosed with dementia. In contrast, of the 108,388 participants without adult ADHD, just 7 percent (7,630 participants) developed dementia. Intriguingly, adults with ADHD who were taking a psychostimulant medication such as Ritalin or Adderall did not have an increased risk of developing dementia compared with those not taking medication. Only 22.3 percent of people with ADHD had taken a psychostimulant medication at any point.
The Post also notes the work of Sara Becker, a postdoctoral research associate at the University of Calgary. "In a 2023 systematic review, Becker and her colleagues identified only seven previous studies investigating the link between ADHD and neurodegenerative diseases such as dementia, most of which found that adult ADHD conferred a higher dementia risk."
The research highlights the importance of seeking care — and the need for more research. Treatment with psychostimulant medications may attenuate the risk, said Stephen Levine, a professor at the University of Haifa's School of Public Health in Israel and the lead author of the study. Lifestyle changes, such as better sleep and staying socially engaged, can also lower risk for dementia....

A 2020 landmark study by the Lancet Commission highlighted 12 modifiable factors for dementia that, if addressed, could mitigate the risk of dementia by up to 40 percent. Some of these factors are hearing loss, excessive alcohol intake and smoking.
Other lifestyle changes that lower your risk of demential include keeping up your physical activity, and eating a Mediterranean diet, the Post reports (citing cognitive neurologist Sandra Black).

An estimated 3 percent of adults have ADHD.

Abner Li reports via 9to5Google: Google today detailed its research into audioplethysmography (APG) that adds heart rate sensing capabilities to active noise canceling (ANC) headphones and earbuds "with a simple software upgrade." Google says the "ear canal [is] an ideal location for health sensing" given that the deep ear artery "forms an intricate network of smaller vessels that extensively permeate the auditory canal."

This audioplethysmography approach works by "sending a low intensity ultrasound probing signal through an ANC headphone's speakers. This signal triggers echoes, which are received via on-board feedback microphones. We observe that the tiny ear canal skin displacement and heartbeat vibrations modulate these ultrasound echoes." A model that Google created works to process that feedback into a heart rate reading, as well as heart rate variability (HRV) measurement. This technique works even with music playing and "bad earbuds seals." However, it was impacted by body motion, and Google countered with a multi-tone approach that serves as a calibration tool to "find the best frequency that measures heart rate, and use only the best frequency to get high-quality pulse waveform."

Google performed two sets of studies with 153 people that found APG "achieves consistently accurate heart rate (3.21% median error across participants in all activity scenarios) and heart rate variability (2.70% median error in inter-beat interval) measurements." Compared to existing HR sensors, it's not impacted by skin tones. Ear canal size and "sub-optimal seal conditions" also do not impact accuracy. Google believes this is a better approach than putting traditional photoplethysmograms (PPG) and electrocardiograms (ECG) sensors, as well as a microcontroller, in headphones/earbuds: "this sensor mounting paradigm inevitably adds cost, weight, power consumption, acoustic design complexity, and form factor challenges to hearables, constituting a strong barrier to its wide adoption."

Jeff Foust reports via SpaceNews: The governments of Australia and the United States have signed an agreement that could allow American rockets to launch from Australian spaceports, although it is unclear how much demand there is for them. The U.S. State Department announced Oct. 26 that the two countries signed a technology safeguards agreement (TSA) regarding space launches from Australia. The agreement provides the "legal and technical framework" for American launches from Australian facilities while protecting sensitive technologies.

The TSA is required to allow the export of U.S.-built launch vehicles to Australia. Industry officials in Australia said the agreement will allow spaceport projects there to sign long-awaited deals to host launches by American companies. [...] The precise demand for Australian launch sites from American launch companies remains unclear. The ELA statement included an illustration of four small launch vehicles from ABL Space Systems, Astra, Phantom Space and Vaya Space, as well as Rocket Lab's Neutron medium-lift rocket. "We hear regularly from both the U.S. government and industry of their demand for this capability in Australia," said Jeremy Hallett, executive chairman of the Space Industry Association of Australia, in a statement. "This agreement removes the blockage stopping this demand being met by Australian space industry and we look forward to the new business opportunities that will emerge for the industry."

An anonymous reader quotes a report from KOMO News: A groundbreaking medical procedure for those with kidney stones will soon be offered at the University of Washington after more than two decades of research. It will also give astronauts the go ahead they need from NASA to travel to Mars. It's a groundbreaking procedure to get rid of painful stones while you're awake, no anesthesia needed. "This has the potential to be game changing," said Dr. Kennedy Hall with UW Medicine. Still being run through clinical trials at UW Medicine, the procedure called burst wave lithotripsy uses an ultrasound wand and soundwaves to break apart the kidney stone. Ultrasonic propulsion is then used to move the stone fragments out, potentially giving patients relief in 10 minutes or less.

This technology is also making it possible for astronauts to travel to Mars, since astronauts are at a greater risk for developing kidney stones during space travel. It's so important to NASA, the space agency has been funding the research for the last 10 years. "They could potentially use this technology while there, to help break a stone or push it to where they could help stay on their mission and not have to come back to land," said Harper. The research has been published in the Journal of Urology.

Efforts to curb emissions of a powerful greenhouse gas commonly produced as a by-product of refrigerant manufacture might be falling short, and it seems eastern China is a major culprit. Nature: The hydrofluorocarbon gas, HFC-23, is around 14,700 times as powerful as carbon dioxide at warming the globe and has long been the subject of national and international climate-change mitigation efforts. Those efforts gained new traction nearly a decade ago when China and India -- the world's largest producers of the chemical -- agreed to dial down its emissions. New research, however, confirms that emissions continued to rise in subsequent years, and an analysis of data from atmospheric-monitoring stations suggests that factories in eastern China are responsible for nearly half of the total.

The rogue emissions are one of several air-pollution sources under discussion at the latest meeting of the Montreal Protocol, held in Nairobi, Kenya, this week. Signed in 1987, the Montreal Protocol is generally considered the most effective international environmental treaty in history, having halted the destruction of the ozone layer while also slowing down global warming. But scientists have often played a role, scanning the atmosphere for chemicals, such as ozone-depleting chlorofluorocarbons (CFCs), that governments have agreed to phase out. "Science has been instrumental in evaluating compliance under the treaty," says Megan Lickley, a climate scientist at Georgetown University in Washington DC.

Antonio Regaladoarchive, reporting for MIT Technology Review: The gene-editing technology CRISPR has been used to change the genes of human babies, to modify animals, and to treat people with sickle-cell disease. Now scientists are attempting a new trick: using CRISPR to permanently cure people of HIV. In a remarkable experiment, a biotechnology company called Excision BioTherapeutics says it added the gene-editing tool to the bodies of three people living with HIV and commanded it to cut, and destroy, the virus wherever it is hiding. The early-stage study is a probing step toward the company's eventual goal of curing HIV infection with a single intravenous dose of a gene-editing drug. Excision, which is based in San Francisco, says the first patient received treatment about a year ago.

This week, doctors involved in the study reported at a meeting in Brussels that the treatment appeared safe and did not have major side-effects. However, they withheld early data about the treatment's effects, leaving outside experts guessing whether it had worked. "This is an exceptionally ambitious and important trial," says Fyodor Urnov, a genome-editing expert at the University of California, Berkeley, who believes it "would be good to know sooner than later" what the effect was -- "including, potentially, no effect."

A failure wouldn't come as a surprise to anyone familiar with HIV. It has proved a devious adversary: there is still no vaccine, even 40 years after the virus was identified in 1983. Still, pharmaceutical companies did develop antiretroviral drugs, which stop the virus from copying itself. Taking these pills lets people with HIV live normal lives. But if they stop, the virus will quickly rebound and, if left unchecked, cause the fatal syndrome of infections and cancers known as AIDS. One reason the virus can't be fully wiped out with drugs alone is that it inserts its genetic material into the DNA of our cells, leaving behind hidden copies that can restart the infection.

A new study published in the British Journal of Sports Medicine finds that about 22 minutes a day of moderate to vigorous activity may combat the negative effects of prolonged sitting. Furthermore, they researchers found that as a person's activity level increases, the risk of dying prematurely from any cause goes down. NBC News reports: In the study, researchers looked at information from nearly 12,000 people ages 50 and older in four datasets from Norway, Sweden and the United States. In those datasets, the participants wore movement detection devices on their hips for 10 hours a day for at least four days. All of the individuals included in the new study were tracked for at least two years. In the new analysis, the researchers accounted for factors, including medical conditions, that could've affected risk of early death. About half of the participants spent 10 1/2 hours or more sedentary each day.

When the researchers linked the participants' information with death registries in the different countries, they found that over an average of five years, 805 people, or 17%, had died. Of those who died, 357, or 6%, had spent less than 10 1/2 hours a day seated, while 448 averaged 10 1/2 hours or more sedentary. Sitting for more than 12 hours a day, the researchers found, was associated with a 38% increased risk of death as compared to eight hours, but only among those who managed to get less than 22 minutes of moderate to vigorous activity a day.

The risk of death went down with increasing amounts of physical activity. An extra 10 minutes a day translated into a 15% lower risk of death among those spending fewer than 10 1/2 hours seated and a 35% lower risk among those who spent more than 10 1/2 hours sedentary each day. Lower intensity activity only made a difference among participants who spent 12 or more hours sitting every day. The study's lead author, Edvard Sagelv, a researcher at The Arctic University of Norway, broke the findings down into manageable terms. "Think of it: only 20 minutes of this a day is enough, meaning, a small stroll of 10 minutes twice a day -- like jumping off the bus one stop before your actual destination to work and then when taking the bus back home, jumping off one stop before."

According to a new study published in iScience, the way pigeons problem-solve matches artificial intelligence. The Guardian reports: In the study, 24 pigeons were given a variety of visual tasks, some of which they learned to categorize in a matter of days, and others in a matter of weeks. The researchers found evidence that the mechanism that pigeons used to make correct choices is similar to the method that AI models use to make the right predictions. "Pigeon behavior suggests that nature has created an algorithm that is highly effective in learning very challenging tasks," said Edward Wasserman, study co-author and professor of experimental psychology at the University of Iowa. "Not necessarily with the greatest speed, but with great consistency."

On a screen, pigeons were shown different stimuli, like lines of different width, placement and orientation, as well as sectioned and concentric rings. Each bird had to peck a button on the right or left to decide which category they belonged to. If they got it correct, they got food, in the form of a pellet; if they got it wrong, they got nothing. "Pigeons don't need a rule," said Brandon Turner, lead author of the study and professor of psychology at Ohio State University. Instead they learn through trial and error. For example, when they were given a visual, say "category A", anything that looked close to that they also classified as "category A", tapping into their ability to identify similarities.

Over the course of the experiments, pigeons improved their ability to make right choices from 55% to 95% of the time when it came to some of the simpler tasks. Presented with a more complex challenge, their accuracy went up from 55% to 68%. In an AI model, the main goal is to recognize patterns and make decisions. Pigeons, as research shows, can do the same. Learning from consequences, when not given a food pellet, pigeons have a remarkable ability to correct their errors. Similarity function is also at play for pigeons, by using their ability to find resemblance between two objects. "With just those two mechanisms alone, you can define a neural network or an artificial intelligent machine to basically solve these categorization problems," said Turner. "It stands to reason that the mechanisms that are present in the AI are also present in the pigeon."

Alexandra Witze reports via Nature: A meteorite that slammed into Mars in September 2021 has rewritten what scientists know about the planet's interior. By analysing the seismic energy that vibrated through the planet after the impact, researchers have discovered a layer of molten rock that envelops Mars's liquid-metal core. The finding, reported today in two papers in Nature, means that the Martian core is smaller than previously thought. It also resolves some lingering questions about how the red planet formed and evolved over billions of years.

The discovery comes from NASA's InSight mission, which landed a craft with a seismometer on Mars's surface. Between 2018 and 2022, that instrument detected hundreds of "marsquakes' shaking the planet. In July 2021, on the basis of the mission's observations of 11 quakes, researchers reported that the liquid core of Mars seemed to have a radius of around 1,830 kilometers3. That was bigger than many scientists were expecting. And it suggested that the core contained surprisingly high amounts of light chemical elements, such as sulfur, mixed with iron. But the September 2021 meteorite impact "unlocked everything," says Henri Samuel, a geophysicist at the Institute of Earth Physics of Paris and lead author of one of today's papers1. The meteorite struck the planet on the side opposite to where InSight was located. That's much more distant than the marsquakes that InSight had previously studied, and allowed the probe to detect seismic energy traveling all the way through the Martian core4. "We were so excited," says Jessica Irving, a seismologist at the University of Bristol, UK, and a co-author of Samuel's paper.

For Samuel, it was an opportunity to test his idea that a molten layer of rock surrounds Mars's core5. The way the seismic energy traversed the planet showed that what scientists had thought was the boundary between the liquid core and the solid mantle, 1,830 kilometers from the planet's centre, was actually a different boundary between liquid and solid. It was the top of the newfound layer of molten rock meeting the mantle (see 'Rethinking the Martian core'). The actual core is buried beneath that molten-rock layer and has a radius of only 1,650 kilometers, Samuel says. The revised core size solves some puzzles. It means that the Martian core doesn't have to contain high amounts of light elements -- a better match to laboratory and theoretical estimates. A second liquid layer inside the planet also meshes better with other evidence, such as how Mars responds to being deformed by the gravitational tug of its moon Phobos.

The second paper in Nature today2, from a team independent of Samuel's, agrees that Mars's core is enveloped by a layer of molten rock, but estimates that the core has a radius of 1,675 kilometers. The work analyzed seismic waves from the same distant meteorite impact, as well as simulations of the properties of mixtures of molten elements such as iron, nickel and sulfur at the high pressures and temperatures in the Martian core. Having molten rock right up against molten iron "appears to be unique," says lead author Amir Khan, a geophysicist at ETH Zurich. "You have this peculiarity of liquid-liquid layering, which is something that doesn't exist on the Earth." The molten-rock layer might be left over from a magma ocean that once covered Mars. As it cooled and solidified into rock, the magma would have left behind a deep layer of radioactive elements that still release heat and keep rock molten at the base of the mantle, Samuel says.