Science

Do Cognitive Abilities Predict Performance in Everyday Computer Tasks? (scitechdaily.com) 110

"Researchers say that a person's intelligence plays a bigger role in their computer proficiency than previously believed," writes SciTechDaily, "so much so that practice alone may not be enough to ensure ease of use."

A new study has found that general cognitive abilities, such as perception, reasoning, and memory, are more important than previously believed in determining a person's ability to perform everyday tasks on a computer... "It is clear that differences between individuals cannot be eliminated simply by means of training," says Antti Oulasvirta [a professor at Finland's Aalto University who conducted extensive human-computer interaction research with his team and the University of Helsinki Department of Psychology]. "In the future, user interfaces need to be streamlined for simpler use. This age-old goal has been forgotten at some point, and awkwardly designed interfaces have become a driver for the digital divide.

"We cannot promote a deeper and more equal use of computers in society unless we solve this basic problem," Oulasvirta says...

This is the first-ever study to measure users' actual ability to perform daily tasks on a PC, as previous studies have relied on participants self-assessing their abilities via questionnaires... "The study revealed that, in particular, working memory, attention, and executive functions stand out as the key abilities. When using a computer, you must determine the order in which things are done and keep in mind what has already been done. A purely mathematical or logical ability does not help in the same way," says university lecturer Viljami Salmela [from the University of Helsinki].

"Our results suggest that contemporary user interfaces are getting so complex that their design is starting to affect inclusivity," their paper concludes, saying that it ultimately raises a question. "How can we design user interfaces to decrease the role of cognitive abilities."
Space

For the First Time Astronomers Watch a Black Hole 'Wake Up' in Real-Time (popsci.com) 18

Black holes "often exhibit long periods of dormancy," writes Popular Science, adding that astronomers had never witnessed a black hole "wake up" in real time. "Until now..."

In February of 2024 X-ray bursts were spotted coming out of a black hole named Ansky by Lorena Hernández-García at Chile's Valparaiso University, according to the article. And what astronomers have now seen "challenges prevailing theories about black hole lifecycles." Hernández-García and collaborators then determined the black hole was displaying a phenomenon known as a quasiperiodic eruption, or QPE [a short-lived flaring event...] While a black hole inevitably destroys everything it captures, objects behave differently during their impending demise. A star, for example, generally stretches apart into a bright, hot, fast-spinning disc known as an accretion disc. Most astronomers have theorized that black holes generate QPEs when a comparatively small object like a star or even a smaller black hole collides with an accretion disc. In the case of Ansky, however, there isn't any evidence linking it to the death of a star.

"The bursts of X-rays from Ansky are ten times longer and ten times more luminous than what we see from a typical QPE," said MIT PhD student and study co-author Joheen Chakraborty. "Each of these eruptions is releasing a hundred times more energy than we have seen elsewhere. Ansky's eruptions also show the longest cadence ever observed, of about 4.5 days." Astronomers must now consider other explanations for Ansky's remarkable behavior. One theory posits that the accretion disc could come from nearby galactic gas pulled in by the black hole instead of a star. If true, then the X-rays may originate from high energy shocks to the disc caused by a small cosmic object repeatedly passing through and disrupting orbital matter.

It's detailed in a study published on April 11 in Nature Astronomy....

Meanwhile, scientists "have uncovered the strongest evidence yet for the existence of elusive intermediate-mass black holes," reports SciTechDaily.

And there's more black hole news from RockDoctor (Slashdot reader #15,477): Given the recent work on galaxy-centre Super-Massive Black Holes (SMBHs), you may be surprised to learn that the only Stellar-Mass Black Holes (SMBHs ... uh, "BHs") identified to-date have been by their gravitational waves, as they merge with another BH or a neutron star. But the long-running OGLE (Optical Gravitational Lensing Experiment) project (1992 — present) has recently confirmed that it has detected an isolated BH not orbiting another bright object, or "swallowing" much of anything...

In this case, 16 other telescopes performed sensitive astrometry (position measurement) over 11 years including the Hubble Space Telescope (HST). These multiple measurements plot an ellipse on the sky, mirroring the movement of the Earth around it's orbit — parallax. Which means this is a relatively close object (1520 parsecs / ~5000 light years).... And there is no sign of a third light emitting body nearby, which means this is an isolated black hole, not orbiting any other body (or, indeed, with any other [small] star orbiting it).

Math

Leaving Money on the Table (nber.org) 54

Abstract of a paper on NBER: There is much disagreement about the extent to which financial incentives motivate study participants. We elicit preferences for being paid for completing a survey, including a one-in-twenty chance of winning a $100 electronic gift card, a guaranteed electronic gift card with the same expected value, and an option to refuse payment. More than twice as many participants chose the lottery as chose the guaranteed payment. Given that most people are risk averse, this pattern suggests that factors beyond risk preferences -- such as hassle costs -- influenced their decision-making. Almost 20 percent of participants actively refused payment, demonstrating low monetary motivation. We find both systematic and unobserved heterogeneity in the characteristics of who turned down payment. The propensity to refuse payment is more than four times as large among individuals 50 and older compared to younger individuals, suggesting a tradeoff between financially motivating participants and obtaining a representative sample. Overall, our results suggest that modest electronic gift card payments violate key requirements of Vernon Smith's induced value theory.
Science

Germany To Create 'Super-High-Tech Ministry' For Research, Technology and Aerospace (science.org) 34

Germany will get a new "super-high-tech ministry" responsible for research, technology, and aerospace, according to the coalition agreement published by the incoming government this week. From a report: The announcement is one of several nods to science in the 144-page agreement, unveiled on 9 April following weeks of negotiations between the center-right Christian Democrats (CDU) and its sister party, the Christian Social Union in Bavaria (CSU) -- who together won the most seats in February's federal elections -- and the center-left Social Democrats. The agreement is expected to be formally approved by the three parties by early May, paving the way for CDU leader Friedrich Merz to be elected chancellor.

[...] The new agreement lists a number of scientific priorities for the new government, including support for artificial intelligence, quantum technologies, biotechnology, microchip development and production, and fusion energy. "Our goal is that the world's first fusion reactor should be realized in Germany," the text states. It also mentions personalized medicine, oceans research, and sustainability research as "strategic" areas. But the agreement does not include any budget estimates, and observers caution it is unclear where the money for new programs would come from. The agreement does affirm current commitments to increase the budgets of the country's main research organizations by 3% per year through 2030.

Science

FDA Plans To Phase Out Animal Testing Requirements (axios.com) 43

The Food and Drug Administration says it would begin phasing out animal testing requirements for antibody therapies and other drugs and move toward AI-based models and other tools it deems "human-relevant." Axios: The FDA said it would launch a pilot program over the next year allowing select developers of monoclonal antibodies to use a primarily non-animal-based testing strategy. Commissioner Marty Makary in a statement said the shift would improve drug safety, lower research and development costs and address ethical concerns about animal experimentation.
Science

Scientists Recreate Brain Circuit in Lab For First Time (nature.com) 20

Scientists have recreated in a laboratory the sensory pathway that transmits feelings of pain to the human brain, in a breakthrough that could lead to better treatments. Financial Times: A team at Stanford University in California is the first to combine different neurons grown from human stem cells into a functioning brain circuit in a lab dish. Their experiments, published in Nature on Wednesday, illustrate scientists' rapid progress in replicating living tissues and organs through synthetic biology.

When the Stanford scientists exposed the brain circuit they had created to sensory stimulants, they observed waves of electrical activity travelling along it. The molecule that makes chilli peppers hot, capsaicin, immediately induced a strong response.

[...] The synthetic brain circuits could be used to screen for better-targeted therapies for pain that tone down excessive waves of neurotransmission, without affecting the brain's reward circuitry as opioids do, project leader [Sergiu] Pasca said. The assembloids themselves cannot be said to "feel pain," he emphasised: "They transmit nervous signals that are processed by a second pathway going deeper into the brain and giving us the aversive, emotional component of pain."

AI

The AI Therapist Can See You Now (npr.org) 115

New research suggests that given the right kind of training, AI bots can deliver mental health therapy with as much efficacy as -- or more than -- human clinicians. From a report: The recent study, published in the New England Journal of Medicine, shows results from the first randomized clinical trial for AI therapy. Researchers from Dartmouth College built the bot as a way of taking a new approach to a longstanding problem: The U.S. continues to grapple with an acute shortage of mental health providers. "I think one of the things that doesn't scale well is humans," says Nick Jacobson, a clinical psychologist who was part of this research team. For every 340 people in the U.S., there is just one mental health clinician, according to some estimates.

While many AI bots already on the market claim to offer mental health care, some have dubious results or have even led people to self-harm. More than five years ago, Jacobson and his colleagues began training their AI bot in clinical best practices. The project, says Jacobson, involved much trial and error before it led to quality outcomes. "The effects that we see strongly mirror what you would see in the best evidence-based trials of psychotherapy," says Jacobson. He says these results were comparable to "studies with folks given a gold standard dose of the best treatment we have available."

Science

No, the Dire Wolf Has Not Been Brought Back From Extinction (newscientist.com) 63

Colossal Biosciences has claimed it "successfully restored" the extinct dire wolf after a "10,000+ year absence," but scientists clarify these are actually genetically modified grey wolves. The U.S. company announced three pups -- males Remus and Romulus born in October, and female Khaleesi born in January -- as dire wolves, but made only 20 genetic edits to grey wolves.

Beth Shapiro of Colossal told New Scientist that just 15 modifications were based on dire wolf DNA, primarily targeting size, musculature and ear shape. Five other changes involve mutations known to produce light coats in grey wolves. A 2021 DNA study revealed dire wolves and grey wolves last shared a common ancestor about 6 million years ago, with jackals and African wild dogs more closely related to grey wolves.
The Internet

Scientists Debate Actual Weight of the Internet (wired.com) 54

The internet's physical mass remains contested among scientists, with estimates ranging from a strawberry to something almost unimaginably small. In 2006, Harvard physicist Russell Seitz calculated the internet weighed roughly 50 grams based on server energy, a figure that would now equate to potato-weight given internet growth.

Christopher White, president of NEC Laboratories America, has dismissed this calculation as "just wrong." White suggests a more accurate method that accounts for the energy needed to encode all internet data in one place, yielding approximately 53 quadrillionths of a gram at room temperature. Alternatively, if the internet's projected 175 zettabytes of data were stored in DNA -- a storage medium scientists are actively exploring -- it would weigh 960,947 grams, equivalent to 10.6 American males. Though scientists debate measurement methods, White asserts the web's true complexity makes it "essentially unknowable."
Medicine

America's NIH Scientists Have a Cancer Breakthrough. Layoffs are Delaying It. (msn.com) 302

Scientists "demonstrated a promising step toward using a person's own immune cells to fight gastrointestinal cancers" at America's National Institutes of Health (or NIH), reports the Washington Post.

But the results were published in Nature Medicine on Tuesday — "the same day the agency was hit with devastating layoffs..." The treatment approach is still early in its development; the personalized immunotherapy regimen shrank tumors in only about a quarter of the patients with colon, rectal and other GI cancers enrolled in a clinical trial. But a researcher who was not involved in the study called the results "remarkable" because they highlight a path to a frustratingly elusive goal in medicine — harnessing a person's own immune defenses to target common solid tumor cancers. Until now, cell-based immunotherapy has worked mainly on blood cancers, such as leukemia, but not the solid cancers that seed tumors in the breast, brain, lungs, pancreas and GI tract...

But the progress arrives at a sad time for science — and for patients, said the leader of the work, NIH immunotherapy pioneer Steven Rosenberg. Two patients' treatments using the experimental therapy had to be delayed because NIH's capacity to make personalized cell therapies has been slowed by the firing of highly skilled staff and by purchasing slowdowns. Those occurred even before major layoffs took place Tuesday... The Department of Health and Human Services (HHS) responded to an email asking about clinical trial delays with a statement: "NIH and HHS are complying with President Trump's executive order."

It's "a very exciting study," said Patrick Hwu, president of the Moffitt Cancer Center in Tampa. Finding ways to tailor this cell-based immunotherapy approach to common solid tumors that cause the vast majority of cancer deaths has remained a major scientific challenge... Rosenberg and colleagues first tried to create tumor infiltrating lymphocytes [or "TILs"] using the method that worked in melanoma for 18 patients with GI cancers that had spread. It failed completely. In a second iteration, his team sequenced the mutations present in each patient's tumor and used that information to sift out and expand the TILs that could home in on that patient's specific tumor cells. The results were far from a triumph, but provided a clue — this time, three of 39 patients' tumors shrank. In the last stage of the trial, the scientists added a drug called pembrolizumab that takes the brakes off immune cells. This time, eight of the 34 patients responded.

"Right now, only a few labs in the country can do what they just did," Hwu said.

While Rosenberg is already working "to refine and improve upon the results," he told the Post that two scientists involved in the specialized process of preparing the cells to treat patients were fired in the probationary purge. "We've had to slow down our work and delay the treatment of some patients...."

And there's also dramatically fewer people now who can purchase research materials, which the Post says it "making it slower and more difficult to obtain supplies."
Mars

Could We Reach Mars Faster With Nuclear Fusion-Powered Rockets? (cnn.com) 81

Nuclear fusion — which releases four times the energy of fission — could theoretically happen sooner in space than on earth, reports CNN.

"And it could help spacecraft achieve speeds of up to 500,000 miles (805,000 kilometers) per hour — more than the fastest object ever built..." With funding from the UK Space Agency, British startup Pulsar Fusion has unveiled Sunbird, a space rocket concept designed to meet spacecraft in orbit, attach to them, and carry them to their destination at breakneck speed using nuclear fusion... For now, Sunbird is in the very early stages of construction and it has exceptional engineering challenges to overcome, but Pulsar says it hopes to achieve fusion in orbit for the first time in 2027. [Pulsar's founder/CEO says the first functional Sunbird would be ready four to five years later.]

If the rocket ever becomes operational, it could one day cut the journey time of a potential mission to Mars in half.

CNN says the proposed Sunbird process would use helium-3 — which may be abundant on the Moon — to generate protons which "can be used as a 'nuclear exhaust' to provide propulsion". (And without generating any dangerous radioactive material.) "It's very unnatural to do fusion on Earth," says Richard Dinan, founder and CEO of Pulsar. "Fusion doesn't want to work in an atmosphere. Space is a far more logical, sensible place to do fusion, because that's where it wants to happen anyway...."

Sunbirds would operate similarly to city bikes at docking stations, according to Dinan: "We launch them into space, and we would have a charging station where they could sit and then meet your ship," he says. "You turn off your inefficient combustion engines, and use nuclear fusion for the greater part of your journey. Ideally, you'd have a station somewhere near Mars, and you'd have a station on low Earth orbit, and the (Sunbirds) would just go back and forth...." Initially, the Sunbirds will be offered for shuttling satellites in orbit, but their true potential would come into play with interplanetary missions. The company illustrates a few examples of the missions that Sunbird could unlock, such as delivering up to 2,000 kilograms (4,400 pounds) of cargo to Mars in under six months, deploying probes to Jupiter or Saturn in two to four years (NASA's Europa Clipper, launched in 2024 towards one of Jupiter's moons, will arrive after 5.5 years), and an asteroid mining mission that would complete a round trip to a near-Earth asteroid in one to two years instead of three.

Other companies are working on nuclear fusion engines for space propulsion, including Pasadena-based Helicity Space, which received investment from aerospace giant Lockheed Martin in 2024. San Diego-based General Atomics and NASA are working on another type of nuclear reactor — based on fission rather than fusion — which they plan to test in space in 2027.

NASA

After 48 Years, Voyager Scientist Confronts the Mission's Final Years (gizmodo.com) 23

"I started working on Voyager in 1977," the Voyager mission's project scientist told Gizmodo Saturday in a new interview. "It was my first job out of college."

35 years later, a Voyager probe became the first spacecraft to cross into interstellar space in 2012, with Voyager 2 following in 2018. But while each Voyager spacecraft carries 10 scientific instruments, all but three have now been turned off to conserve power, Gizmodo writes. "The two spacecraft now have enough power to operate for another year or so before engineers are forced to turn off two more instruments..." Voyager Mission Project Scientist Linda Spilker: The number of people that are working on and flying Voyager is a whole lot smaller than it was in the planetary days... The challenge was, can we reach the heliopause? We didn't know where it was, we had no idea how far away it was. We got to Neptune, and then we thought, "well, maybe it's just another 10 [astronomical units] or so, a little bit further, a little bit further." And so every time we got a little bit further, the modelers would go back, scratch their heads and say, "ah, it could be a little bit more, a little bit farther away," and so on and on that continued, until finally, Voyager 1 crossed the heliopause in 2012...

Gizmodo: Is it an emotional decision to turn off Voyager's instruments?

Spilker: I was talking to the cosmic ray instrument lead, and I said, "Wow, this must really be tough for you to see your instrument turned off." He helped build the instrument in the early 1970s. This instrument that's been sending you data, and that's been part of your life for over 50 years now. And he said, it was hard to think about turning it off for the whole team. It's kind of like losing a best friend, or someone that's been a part of your life for so many years, and then suddenly, it's silent. At the same time, there's this pride that you were part of that, and your instrument got so much great data — so it's a mix of emotions...

The spacecraft had a lot of redundancy on it, so that means two of every computer and two of all the key components. We've been able to turn off those backup units, but we're now at the point where, to really get a significant amount of power, all that's left are some of the science instruments to turn off. So, that's where we're at... How cold can the lines get before they freeze? How cold can some of these other components get before they stop working? So that's another challenge. Then there are individual tiny thrusters that align the spacecraft and keep that antenna pointed at the Earth so we can send the data back, and they're very slowly clogging up with little bits of silica, and so their puffs are getting weaker and weaker. That's another challenge that we're going through to balance.

But we're hopeful that we can get one, possibly two, spacecraft to the 50th anniversary in 2027. Voyager's golden anniversary, and perhaps even into the early 2030s with one, maybe two, science instruments.

"We're well past the warranty of four years..." Spilker says at one point. And "We're still working and thinking about an interstellar probe that would go much, much farther than Voyager.

"You're talking about a multi-generation mission."
ISS

Starliner's Space Station Flight Was 'Wilder' Than We Thought (arstechnica.com) 97

The Starliner spacecraft lost four thrusters while approaching the International Space Station last summer. NASA astronaut, Butch Wilmore took manual control, remembers Ars Technica, "But as Starliner's thrusters failed, Wilmore lost the ability to move the spacecraft in the direction he wanted to go..." Starliner had flown to within a stone's throw of the space station, a safe harbor, if only they could reach it. But already, the failure of so many thrusters violated the mission's flight rules. In such an instance, they were supposed to turn around and come back to Earth. Approaching the station was deemed too risky for Wilmore and Williams, aboard Starliner, as well as for the astronauts on the $100 billion space station.

But what if it was not safe to come home, either?

"I don't know that we can come back to Earth at that point," Wilmore said in an interview. "I don't know if we can. And matter of fact, I'm thinking we probably can't."

After a half-hour exclusive interview, Ars Technica's senior space editor Eric Berger says he'd heard "a hell of a story." After Starliner lost four of its 28 reaction control system thrusters, Van Cise and this team in Houston decided the best chance for success was resetting the failed thrusters. This is, effectively, a fancy way of turning off your computer and rebooting it to try to fix the problem. But it meant Wilmore had to go hands-off from Starliner's controls. Imagine that. You're drifting away from the space station, trying to maintain your position. The station is your only real lifeline because if you lose the ability to dock, the chance of coming back in one piece is quite low. And now you're being told to take your hands off the controls...

Two of the four thrusters came back online.

Wilmore: "...But then we lose a fifth jet. What if we'd have lost that fifth jet while those other four were still down? I have no idea what would've happened. I attribute to the providence of the Lord getting those two jets back before that fifth one failed...

Berger: Mission Control decided that it wanted to try to recover the failed thrusters again. After Wilmore took his hands off the controls, this process recovered all but one of them. At that point, the vehicle could be flown autonomously, as it was intended to be.

"Wilmore added that he felt pretty confident, in the aftermath of docking to the space station, that Starliner probably would not be their ride home," according to the article. And Williams says it was the right decision. Publicly, NASA and Boeing expressed confidence in Starliner's safe return with crew. But Williams and Wilmore, who had just made that harrowing ride, felt differently.
ISS

NASA Seeks Proposals for Two More Private Astronaut Space Station Visits (spacenews.com) 31

This week NASA "issued a solicitation for the next two private astronaut missions to the International Space Station," reports Space News. Scheduled after May of 2026 and then mid-2027, "These will be the fifth and sixth such missions to the ISS, part of a broader low Earth orbit commercialization effort by NASA with the ultimate goal of replacing the International Space Station with one or more commercial stations."

NASA's Space Station program manager calls the missions "a key part" of helping industry partners "gain the experience needed to train and manage crews, conduct research, and develop future destinations." In short, they see the missions "providing companies with hands-on opportunities to refine their capabilities and build partnerships that will shape the future of low Earth orbit." [NASA's call for proposals] offers an opportunity to have future missions commanded by someone other than a former NASA astronaut. While companies must propose a commander who meets current requirements, it can also propose an alternate commander who is a former astronaut from the Canadian Space Agency, European Space Agency or Japan Aerospace Exploration Agency with similar ISS experience requirements... ["Broadening of this requirement is not guaranteed," NASA warns.]

That could allow some former astronauts already working with commercial spaceflight companies an opportunity to command private astronaut missions. Axiom Space, for example, announced in July 2024 that former ESA astronaut Tim Peake had joined its astronaut team. That came after Axiom and the U.K. Space Agency signed a memorandum of understanding in October 2023 to study the feasibility of a private astronaut mission crewed exclusively by U.K. astronauts.

So far Axiom Space has been awarded all four private astronaut missions, according to the article, "flying one mission each in 2022, 2023 and 2024. Its next mission, Ax-4, is scheduled for no earlier than May."

But "While Axiom has little or no competition for previous PAM awards, it will likely face stiffer competition this time. Vast, a company also planning to develop commercial space stations, has previously stated its intent to submit proposals..."
Science

Bonobos May Combine Words In Ways Previously Thought Unique To Humans (theguardian.com) 27

A new study shows bonobos can combine vocal calls in ways that mirror human language, producing phrases with meanings beyond the sum of individual sounds. "Human language is not as unique as we thought," said Dr Melissa Berthet, the first author of the research from the University of Zurich. Another author, Dr Simon Townsend, said: "The cognitive building blocks that facilitate this capacity is at least 7m years old. And I think that is a really cool finding." The Guardian reports: Writing in the journal Science, Berthet and colleagues said that in the human language, words were often combined to produce phrases that either had a meaning that was simply the sum of its parts, or a meaning that was related to, but differed from, those of the constituent words. "'Blond dancer' -- it's a person that is both blond and a dancer, you just have to add the meanings. But a 'bad dancer' is not a person that is bad and a dancer," said Berthet. "So bad is really modifying the meaning of dancer here." It was previously thought animals such as birds and chimpanzees were only able to produce the former type of combination, but scientists have found bonobos can create both.

The team recorded 700 vocalizations from 30 adult bonobos in the Democratic Republic of the Congo, checking the context of each against a list of 300 possible situations or descriptions. The results reveal bonobos have seven different types of call, used in 19 different combinations. Of these, 15 require further analysis, but four appear to follow the rules of human sentences. Yelps -- thought to mean "'et's do that" -- followed by grunts -- thought to mean "look at what I am doing," were combined to make "yelp-grunt," which appeared to mean "let's do what I'm doing." The combination, the team said, reflected the sum of its parts and was used by bonobos to encourage others to build their night nests.

The other three combinations had a meaning apparently related to, but different from, their constituent calls. For example, the team found a peep -- which roughly means "I would like to ..." -- followed by a whistle -- appeared to mean "let's stay together" -- could be combined to create "peep-whistle." This combination was used to smooth over tense social situations, such as during mating or displays of prowess. The team speculated its meaning was akin to "let's find peace." The team said the findings in bonobos, together with the previous work in chimps, had implications for the evolution of language in humans, given all three species showed the ability to combine words or vocalizations to create phrases.

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