An anonymous reader quotes a report from The Guardian: Growing up in a greener urban environment boosts children's intelligence and lowers levels of difficult behavior, a study has found. The analysis of more than 600 children aged 10-15 showed a 3% increase in the greenness of their neighborhood raised their IQ score by an average of 2.6 points. The effect was seen in both richer and poorer areas. There is already significant evidence that green spaces improve various aspects of children's cognitive development but this is the first research to examine IQ. The cause is uncertain but may be linked to lower stress levels, more play and social contact or a quieter environment. The increase in IQ points was particularly significant for those children at the lower end of the spectrum, where small increases could make a big difference, the researchers said.

The study, published in the journal Plos Medicine, used satellite images to measure the level of greenness in neighborhoods, including parks, gardens, street trees and all other vegetation. The average IQ score was 105 but the scientists found 4% of children in areas with low levels of greenery scored below 80, while no children scored below 80 in areas with more greenery. The benefits of more greenery that were recorded in urban areas were not replicated in suburban or rural areas. [T]his may be because those places had enough greenness for all children living there to benefit. Behavioral difficulties such as poor attention and aggressiveness were also measured in the children using a standard rating scale, and the average score was 46. In this case, a 3% rise in greenery resulted in a two-point reduction in behavioral problems, in line with previous studies.

phalse phace writes: Researchers in Hong Kong on Monday reported what appears to be the first confirmed case of Covid-19 reinfection, a 33-year-old man who was first infected by SARS-CoV-2 in late March and then, four and a half months later, seemingly contracted the virus again while traveling in Europe. The case raises questions about the durability of immune protection from the coronavirus.

There have been scattered reports of cases of Covid-19 reinfection. Those reports, though, have been based on anecdotal evidence and largely attributed to flaws in testing. But in this case, researchers at the University of Hong Kong sequenced the virus from the patient's two infections and found that they did not match, indicating the second infection was not tied to the first. There was a difference of 24 nucleotides -- the 'letters' that make up the virus' RNA -- between the two infections. Experts cautioned that this patient's case could be an outlier among the tens of millions of cases around the world and that immune protection may generally last longer than just a few months.

A new cluster of Covid-19 cases in New Zealand prompted a widespread investigation to identify where they're coming from. The New Zealand Herald reports: Nearly 90 new cases of Covid-19 have now been linked back to the new cluster, which itself stemmed from an "index case" — a 50-year-old man working at Mt Wellington's Americold coolstore, with no history or link to overseas travel. Contact tracers have been trying to work backwards from that index case, who tested positive on August 11, in hopes of finding the "primary case" — or the person who brought the virus into the country in the first place.

Friday — more than a week and 175,000 tests since the start of the outbreak — Prime Minister Jacinda Ardern shared some details on how exhaustive that process had been. Virtually all of the country's border and managed isolation staff have been tested in the past 10 days, and so far there had been no additional cases, outside the mystery infection of a maintenance worker at Auckland's Rydges hotel...

University of Auckland microbiologist Associate Professor Siouxsie Wiles says it's quite possible we'll never get any further. "Is that a big deal? From the testing we've done so far, it looks like this is a pretty tight cluster — so I would say, no," she said. "What we have lost is the opportunity to know how it happened, or what gaps need plugging. But at the same time, we have to remember that nothing is 100 per cent guaranteed to work all of the time."

A plan to release over 750 million genetically modified mosquitoes into the Florida Keys in 2021 and 2022 received final approval from local authorities, against the objection of many local residents and a coalition of environmental advocacy groups. The proposal had already won state and federal approval. CNN reports: Approved by the Environment Protection Agency in May, the pilot project is designed to test if a genetically modified mosquito is a viable alternative to spraying insecticides to control the Aedes aegypti. It's a species of mosquito that carries several deadly diseases, such as Zika, dengue, chikungunya and yellow fever. The mosquito, named OX5034, has been altered to produce female offspring that die in the larval stage, well before hatching and growing large enough to bite and spread disease. Only the female mosquito bites for blood, which she needs to mature her eggs. Males feed only on nectar, and are thus not a carrier for disease.

The mosquito also won federal approval to be released into Harris County, Texas, beginning in 2021, according to Oxitec, the US-owned, British-based company that developed the genetically modified organism (GMO). The Environmental Protection Agency granted Oxitec's request after years of investigating the impact of the genetically altered mosquito on human and environmental health. "This is an exciting development because it represents the ground-breaking work of hundreds of passionate people over more than a decade in multiple countries, all of whom want to protect communities from dengue, Zika, yellow fever, and other vector-borne diseases," Oxitec CEO Grey Frandsen said in a statement at the time. However, state and local approval for the Texas release has not been granted, said Sam Bissett, a communication specialist with Harris County Public Health.

The EPA permit requires Oxitec to notify state officials 72 hours before releasing the mosquitoes and conduct ongoing tests for at least 10 weeks to ensure none of the female mosquitoes reach adulthood. However, environmental groups worry that the spread of the genetically modified male genes into the wild population could potentially harm threatened and endangered species of birds, insects and mammals that feed on the mosquitoes.

AleRunner writes: In the first half of 2020, Sweden has recorded its highest death total in 150 years. "In total, 51,405 Swedes died in the six-month period, a higher number than in any year since 1869, when 55,431 people died, partly as a result of a famine," reports The Guardian. In what may be a reaction to this failure, which makes Sweden the worst coronavirus country in Scandinavia, Sweden has announced a change to their new contact-tracing policy. The Local explains: "If you test positive for the coronavirus you may now be given instructions to call people with whom you have been in contact and may have infected, instead of healthcare staff doing the job for you, or it not being done at all."

In early June, Sweden switched from its failed "herd immunity" strategy to a contact-tracing strategy and has since seen a strong fall in new infections, though with a recent slight increase. The new contact-tracing strategy will be critical for the return of the Swedish economy with Sweden currently facing travel restrictions from Scandinavian neighbors such as Finland, whilst other Scandinavian and Baltic countries are already open for trade and tourism. Swedes will be hoping that the adjustment of their new coronavirus strategy will be a signpost for other countries rather than the warning of their old strategy.

Not so long ago, in June, we discussed how Sweden's old strategy had made Sweden a Pariah state and in May we had discussed how Sweden's old strategy caused many deaths whilst failing to deliver immunity.

A California resident has tested positive for plague, marking the state's first human case of the disease in five years, according to health officials. Live Science reports: The case was confirmed on Monday in a resident of South Lake Tahoe, according to a statement from the El Dorado County Department of Health and Human Services. The individual is described as an "avid walker" who may have been bitten by an infected flea while walking their dog in the Tahoe Keys area or along the "Truckee River Corridor" north of Highway 50, the statement said.

"Plague is naturally present in many parts of California, including higher elevation areas of El Dorado County," Dr. Nancy Williams, the El Dorado County public health officer, said in the statement. "It's important that individuals take precautions for themselves and their pets when outdoors, especially while walking, hiking and/or camping in areas where wild rodents are present. Human cases of plague are extremely rare but can be very serious." The patient is currently recovering at home under the care of medical professionals, the statement said.

Researchers at NYU Langone Health and Facebook's artificial intelligence division have teamed up to develop an AI model that uses less data and creates images faster than traditional MRI techniques, according to a Wall Street Journal report. From a report: The goal of the project is to create a five-minute MRI as an alternative to the 20 minutes to an hour it takes for current MRI machines to scan a patient, Michael Recht, MD, told the publication. Dr. Recht is professor and chair of New York City-based NYU Langone Health's radiology department and also a co-author of the research project. The combination of AI and MRI technology aims to construct images with less data rather than diagnose a medical condition. The project uses different technology and standards than those used to create AI-generated or synthetic media. Because it centers on constructing MRI scans, Facebook said the project must create images "that are accurate to the ground truth," compared to synthetic media, which usually needs to create a believable image, according to the report.

For the experiment, researchers created 108 patient images using standard MRI techniques as well as a second set of images in which some of the image data was thrown out. Facebook's AI model was then applied to construct the images with less data. Researchers used commercially available MRI machines, and data was collected from patients from various points of their bodies. Six MRI readers reviewed both sets of images, and readings were spaced out across a four-week period to ensure the readers could not recall important details from previous sets. Dr. Recht told the Journal that all six engineers concluded that the quality of the AI model-generated images was "as good [as] or better" than the conventional images. The AI system still needs regulatory approval, but NYU Langone is now using it to treat patients as part of an institutional review board study, according to the report.

Nations that hoard possible COVID-19 vaccines while excluding others will deepen the pandemic, World Health Organization (WHO) chief Tedros Adhanom Ghebreyesus said on Tuesday, issuing a last-ditch call for countries to join a global vaccine pact. From a report: The WHO has an Aug. 31 deadline for wealthier nations to join the "COVAX Global Vaccines Facility" for sharing vaccine hopefuls with developing countries. Tedros said he sent a letter to the WHO's 194 member states, urging participation. The global health agency also raised concerns that the pandemic's spread was being driven now by younger people, many of whom were unaware they were infected, posing a danger to vulnerable groups. Tedros' push for nations to join COVAX comes as the European Union, Britain, Switzerland and the United States strike deals with companies testing prospective vaccines. Russia and China are also working on vaccines, and the WHO fears national interests could impede global efforts.

Haider Warraich, a cardiologist, writing for the New York Times: An intriguing new study from Germany offers a glimpse into how SARS-CoV-2 affects the heart. Researchers studied 100 individuals, with a median age of just 49, who had recovered from Covid-19. Most were asymptomatic or had mild symptoms. An average of two months after they received the diagnosis, the researchers performed M.R.I. scans of their hearts and made some alarming discoveries: Nearly 80 percent had persistent abnormalities and 60 percent had evidence of myocarditis. The degree of myocarditis was not explained by the severity of the initial illness.

Though the study has some flaws, and the generalizability and significance of its findings not fully known, it makes clear that in young patients who had seemingly overcome SARS-CoV-2 it's fairly common for the heart to be affected. We may be seeing only the beginning of the damage. Researchers are still figuring out how SARS-CoV-2 causes myocarditis -- whether it's through the virus directly injuring the heart or whether it's from the virulent immune reaction that it stimulates. It's possible that part of the success of immunosuppressant medications such as the steroid dexamethasone in treating sick Covid-19 patients comes from their preventing inflammatory damage to the heart. Such steroids are commonly used to treat cases of myocarditis. Despite treatment, more severe forms of Covid-19-associated myocarditis can lead to permanent damage of the heart -- which, in turn, can lead to heart failure.

Tim Harford, writing for Financial Times (not paywalled): Last spring, I returned from the holiday of a lifetime in Japan, and reflected on the richness of the memories it had generated. Time flew by while I was there, but in hindsight 10 days somewhere vividly new had produced more memories than 10 weeks back home. I likened the effect to the compression of a film. Instead of storing each frame separately, video compression algorithms will start with the first frame of a scene and then store a series of "diffs" -- changes from one frame to the next. A slow, contemplative movie with long scenes and fixed cameras can be compressed more than a fast-moving action flick. Similarly, a week full of new experiences will seem longer in retrospect. A month of repeating the same routine might seem endless, but will be barely a blip in the memory: the "diffs" are not significant enough for the brain to bother with. After months of working from home, I now realise that there was something incomplete about this account. New experiences are indeed important for planting a rich crop of memories. But, by itself, that is not enough. A new physical space seems to be important if our brains are to pay attention.

The Covid-19 lockdown, after all, was full of new experiences. Some were grim: I lost a friend to the disease; I smashed my face up in an accident; we had to wear masks and avoid physical contact and worry about where the next roll of toilet paper was coming from. Some were more positive: the discovery of new pleasures, the honing of new skills, the overcoming of new challenges. But I doubt I am alone in finding that my memory of the lockdown months is rather thin. No matter how many new people or old friends you talk to on Zoom or Skype, they all start to smear together because the physical context is monotonous: the conversations take place while one sits in the same chair, in the same room, staring at the same computer screen.>

Time magazine reports on is a big scientific advance: "the understanding that our bodies often operate according to different clocks." Although the federal government recommends that Americans sleep seven or more hours per night for optimal health and functioning, new research is challenging the assumption that sleep is a one-size-fits-all phenomenon. Scientists have found that our internal body clocks vary so greatly that they could form the next frontiers of personalized medicine...

Human sleep is largely a mystery. We know it's important; getting too little is linked to heightened risk for metabolic disorders, Type 2 diabetes, psychiatric disorders, autoimmune disease, neurodegeneration and many types of cancer. "It's probably true that bad sleep leads to increased risks of virtually every disorder," says Dr. Louis Ptacek, a neurology professor at the University of California, San Francisco... The ideal sleep duration has long been thought to be universal. "There are many people who think everyone needs eight to eight and a half hours of sleep per night and there will be health consequences if they don't get it," says Ptacek. "But that's as crazy as saying everybody has to be 5 ft. 10 in. tall. It's just not true..."

About a decade ago, Ptacek's wife Ying-Hui Fu discovered the first human gene linked to natural short sleep; people who had a rare genetic mutation seemed to get the same benefits from six hours of sleep a night as those without the mutation got from eight hours. In 2019, Fu and Ptacek discovered two more genes connected to natural short sleep, and they'll soon submit a paper describing a fourth, providing even more evidence that functioning well on less sleep is a genetic trait...

Doctors once dismissed short sleepers as depressed or suffering from insomnia. Yet short sleepers may actually have an edge over everyone else. Research is still early, but Fu has found that besides being more efficient at sleep, they tend to be more energetic and optimistic and have a higher tolerance for pain than people who need to spend more time in bed. They also tend to live longer.

Applehu Akbar shared CNN's article about why some people experience Covid-19 differently: "When we looked in the setting of Covid disease, we found that people who had prior vaccinations with a variety of vaccines — for pneumococcus, influenza, hepatitis and others — appeared to have a lower risk of getting Covid disease," Dr. Andrew Badley, an infectious disease specialist at Mayo Clinic, told CNN's Anderson Cooper on Monday night... There's been no definitive evidence of any other vaccines boosting immunity against Covid-19. But some researchers have suggested it's possible.... Last month, researchers found that countries where many people have been given the tuberculosis vaccine Bacillus Calmette-Guerin had less mortality from coronavirus, a finding that fits with other research suggesting the vaccine can boost people's immunity in general.

But once you're infected, how much of the virus made it into your body could also have an impact on what your experience is, another expert told CNN on Monday. Dr. Monica Gandhi, an infectious disease specialist at University of California, San Francisco, has been working with a team of researchers to understand how more people could go through their infections with minimal or no symptoms. About 40% of people infected with the virus don't have symptoms, according to an estimate last month by the US Centers for Disease Control and Prevention.

Gandhi's team found masks make a difference.

"What the mask does is really reduce the amount of virus that you get in, if you do get infected," she said. "And by reducing that... you have a lower dose, you're able to manage it, you're able to have a calm response and you have mild symptoms or no symptoms at all."

Amid a flurry of concern over reports that frozen chicken wings imported to China from Brazil had tested positive for the coronavirus, experts said on Thursday that the likelihood of catching the virus from food -- especially frozen, packaged food -- is exceedingly low. From a report: "This means somebody probably handled those chicken wings who might have had the virus," said Angela Rasmussen, a virologist at Columbia University. "But it doesn't mean, 'Oh my god, nobody buy any chicken wings because they're contaminated.'" Guidelines from the Centers for Disease Control and Prevention maintain that "there is no evidence to suggest that handling food or consuming food is associated with Covid-19." The main route the virus is known to take from person to person is through spray from sneezing, coughing, speaking or even breathing.

"I make no connection between this and any fear that this is the cause of any long-distance transmission events," said C. Brandon Ogbunu, a disease ecologist at Yale University. When the virus crosses international boundaries, it's almost certainly chauffeured by people, rather than the commercial products they ship. The chicken wings were screened on Wednesday in Shenzhen's Longgang district, where officials have been testing imports for the presence of coronavirus genetic material, or RNA. Several samples taken from the outer packaging of frozen seafood, some of which had been shipped in from Ecuador, recently tested positive for virus RNA in China's Anhui, Shaanxi and Shandong provinces as well. Laboratory procedures that search for RNA also form the basis of most of the coronavirus tests performed in people. But RNA is only a proxy for the presence of the virus, which can leave behind bits of its genetic material even after it has been destroyed, Dr. Ogbunu said. "This is just detecting the signature that the virus has been there at some point," he said.

schwit1 writes: Moviegoers will have to pay only 15 cents for tickets at AMC cinemas on Aug. 20, when the chain starts to reopen amid the coronavirus outbreak. The cheap tickets will be available at more than 100 theaters across the U.S. The deal, a throwback to the price the company charged when it was founded in 1920, is intended to lure customers who may be worried about venturing into a theater because of the risk of contracting COVID-19.

An anonymous reader quotes a report from IFLScience: Promising results have come out of the only active clinical trial for a vaccine against Lyme disease. Valneva, a French biotech company, recently announced its first Phase 2 clinical trial has shown that its vaccine against Lyme disease is both safe and effective. The vaccine works by triggering the body's immune system to produce antibodies for the six common serotypes of the disease that are found in North America and Europe. It does this by introducing an isolated protein of the pathogen to the body, allowing the immune system to recognize and respond to the surface proteins found on the bacteria responsible for Lyme disease, Borrelia burgdorferi.

Over 570 healthy adults in the US and Europe were given one of two dose levels of the vaccine in three injections, while others were given a placebo as a control. Both groups that received the active dose were found to have produced a significant amount of antibodies against each of the six most prevalent Outer Surface Protein A serotypes of B. burgdorferi. [...] This new potential vaccine, known as VLA15, is currently the only active Lyme disease vaccine in clinical development. Back in 1998, the US Food and Drug Administration (FDA) approved a Lyme disease vaccine known as LYMErix. It was withdrawn from the market just three years later following doubts over its effectiveness and other contentions. Much of the controversy, however, was often said to have been kicked up by the anti-vaccination movement, which was growing in momentum at the time.

Moderna's vaccine candidate against Covid-19 protected against the virus in a trial that inoculated 16 monkeys, an encouraging step on the path to a defense for humans against the pandemic. Bloomberg reports: Two injections of the vaccine protected against heavy exposure to the virus at two different levels of dosage, Moderna said in findings published Tuesday in the New England Journal of Medicine. The primates didn't show any sign of creating enhanced disease, a problem that has occasionally been associated with vaccines. The results, if they hold up in humans, suggest that the vaccine may be able to protect against Covid-19 in both the upper and lower airways. In all the monkeys who got the high doses of the vaccine, no viral replication was detectable in their noses two days after being challenged with the virus, according to the study results. And no viral replication was seen in the lung fluid of 7 of 8 animals in both dose groups after being challenged with the virus. All 16 monkeys showed at least some sign of protection, with limited lung inflammation seen in the lungs of both groups. The report says that the phase 3 trial, which involves 30,000 humans, will begin producing data in November or December.

If you're curious about how a vaccine trial works, Slashdot interviewed technology journalist and marketer Jennifer Riggins, who is participating in the Oxford Vaccine Trial.

An anonymous reader quotes a report from The New York Times: In a video posted Monday online, a group of people calling themselves "America's Frontline Doctors" and wearing white medical coats spoke against the backdrop of the Supreme Court in Washington, sharing misleading claims about the virus, including that hydroxychloroquine was an effective coronavirus treatment and that masks did not slow the spread of the virus. [...] The members of the group behind Monday's video say they are physicians treating patients infected with the coronavirus. But it was unclear where many of them practice medicine or how many patients they had actually seen. As early as May, anti-Obamacare conservative activists called the Tea Party Patriots Action reportedly worked with some of them to advocate loosening states' restrictions on elective surgeries and nonemergency care. On July 15, the group registered a website called "America's Frontline Doctors," domain registration records show. One of the first copies of the video that appeared on Monday was posted to the Tea Party Patriots' YouTube channel, alongside other videos featuring the members of "America's Frontline Doctors."

The video did not appear to be anything special. But within six hours, President Trump and his son Donald Trump Jr. had tweeted versions of it, and the right-wing news site Breitbart had shared it. It went viral, shared largely through Facebook groups dedicated to anti-vaccination movements and conspiracy theories such as QAnon, racking up tens of millions of views. Multiple versions of the video were uploaded to YouTube, and links were shared through Twitter. Facebook, YouTube and Twitter worked feverishly to remove it, but by the time they had, the video had already become the latest example of misinformation about the virus that has spread widely. That was because the video had been designed specifically to appeal to internet conspiracists and conservatives eager to see the economy reopen, with a setting and characters to lend authenticity. It showed that even as social media companies have sped up response time to remove dangerous virus misinformation within hours of its posting, people have continued to find new ways around the platforms' safeguards. [...] At least one version of the video, viewed by The Times on Facebook, was watched over 16 million times.

Scientists are conducting preliminary tests of COVID-19 drugs using 3D printed human organs, eliminating the need to perform tests on animals, or, of course, humans. The Week reports: For example, Anthony Atala, the director of the Wake Forest Institute for Regenerative Medicine, and his team are using 3-D printers to create tiny replicas of human organs, including miniature lungs and colons, which are particularly affected by the coronavirus. They send them overnight for testing at a biosafety lab at George Mason University. The idea predated the coronavirus -- Atala said he never thought "we'd be considering this for a pandemic" -- but it could come in handy and help expedite the experimental drug process, especially since Atala said his Winston-Salem, North Carolina-based lab can churn out thousands of printed organs per hour. "The 3-D models can circumvent animal testing and make the pathway stronger from the lab to the clinic," said Akhilesh Gaharwar, who directs a lab in the biomedical engineering at Texas A&M University. Further reading: The New York Times

Long-time Slashdot reader schwit1 shared this article from HealthDay: In earlier studies, patients have pegged CPR survival rates at between 19% and 75%. But the real rate of survival is about 12% for cardiac arrests that occur outside hospitals and between 24% and 40% for those that happen in the hospital, according to the report published online July 13 in the Emergency Medicine Journal.

For the new study, Bandolin's team surveyed 500 emergency department patients and their companions. Fifty-three percent said they had done or witnessed CPR, and 64% had taken a CPR course. Ninety-five percent said their main source of CPR information was television. About half said the success rate of CPR topped 75%. And nine out of 10 said they wanted to receive CPR if it was needed.

But only 28% had discussed CPR with a doctor, the investigators noted in a journal news release.

KFC announced that it will test chicken nuggets made with 3D bioprinting technology in Moscow, Russia, this fall. Business Insider reports: The chicken chain has partnered with 3D Bioprinting Solutions to create a chicken nugget made in a lab with chicken and plant cells using bioprinting. Bioprinting, which uses 3D-printing techniques to combine biological material, is used in medicine to create tissue and even organs. The 3D-printed chicken nuggets will closely mimic the taste and appearance of KFC's original chicken nuggets, according to the press release. KFC expects the production of 3D-printed nuggets to be more environmentally friendly than the production process of its traditional chicken nuggets. The fall release will mark the first debut of a lab-grown chicken nugget at a global fast-food chain like KFC.