Several weeks after taking over Ukraine's southern port city of Kherson, Russian soldiers arrived at the offices of local internet service providers and ordered them to give up control of their networks. From a report: "They came to them and put guns to their head and just said, 'Do this,'" said Maxim Smelyanets, who owns an internet provider that operates in the area and is based in Kyiv. "They did that step by step for each company." Russian authorities then rerouted mobile and internet data from Kherson through Russian networks, government and industry officials said. They blocked access to Facebook, Instagram and Twitter, as well as to Ukrainian news websites and other sources of independent information. Then they shut off Ukrainian cellular networks, forcing Kherson's residents to use Russian mobile service providers instead.

What happened in Kherson is playing out in other parts of Russian-occupied Ukraine. After more than five months of war, Russia controls large sections of eastern and southern Ukraine. Bombings have leveled cities and villages; civilians have been detained, tortured and killed; and supplies of food and medicine are running low, according to witnesses interviewed by The New York Times and human rights groups. Ukrainians in those regions have access only to Russian state television and radio. To cap off that control, Russia has also begun occupying the cyberspace of parts of those areas. That has cleaved off Ukrainians in Russia-occupied Kherson, Melitopol and Mariupol from the rest of the country, limiting access to news about the war and communication with loved ones. In some territories, the internet and cellular networks have been shut down altogether.

The Biden administration declared monkeypox a public health emergency on Thursday as cases topped 6,600 nationwide. From a report: The declaration could facilitate access to emergency funds, allow health agencies to collect more data about cases and vaccinations, accelerate vaccine distribution and make it easier for doctors to prescribe treatment. "We're prepared to take our response to the next level in addressing this virus and we urge every American to take monkeypox seriously and to take responsibility to help us tackle this virus," Department of Health and Human Services Secretary Xavier Becerra said in a Thursday briefing about the emergency declaration. A quarter of U.S. cases are in New York state, which declared a state of emergency last week. California and Illinois followed suit with emergency declarations Monday.

An anonymous reader quotes a report from Phys.Org: Scientists at the University of Virginia School of Medicine and their collaborators have used DNA to overcome a nearly insurmountable obstacle to engineer materials that would revolutionize electronics. One possible outcome of such engineered materials could be superconductors, which have zero electrical resistance, allowing electrons to flow unimpeded. That means that they don't lose energy and don't create heat, unlike current means of electrical transmission. Development of a superconductor that could be used widely at room temperature -- instead of at extremely high or low temperatures, as is now possible -- could lead to hyper-fast computers, shrink the size of electronic devices, allow high-speed trains to float on magnets and slash energy use, among other benefits.

One such superconductor was first proposed more than 50 years ago by Stanford physicist William A. Little. [...] One possible way to realize Little's idea for a superconductor is to modify lattices of carbon nanotubes, hollow cylinders of carbon so tiny they must be measured in nanometers -- billionths of a meter. But there was a huge challenge: controlling chemical reactions along the nanotubes so that the lattice could be assembled as precisely as needed and function as intended.

[Edward H. Egelman, Ph.D., of UVA's Department of Biochemistry and Molecular Genetics] and his collaborators found an answer in the very building blocks of life. They took DNA, the genetic material that tells living cells how to operate, and used it to guide a chemical reaction that would overcome the great barrier to Little's superconductor. In short, they used chemistry to perform astonishingly precise structural engineering -- construction at the level of individual molecules. The result was a lattice of carbon nanotubes assembled as needed for Little's room-temperature superconductor. [...] The lattice they built has not been tested for superconductivity, for now, but it offers proof of principle and has great potential for the future, the researchers say. The findings have been published in the journal Science.

Live and high-resolution images of a patient's internal organs are already possible with ultrasound imaging technology. But currently the technology "requires bulky and specialized equipment available only in hospitals and doctor's offices," explains an annoncement from MIT.

Now a new design by MIT engineers "might make the technology as wearable and accessible as buying Band-Aids at the pharmacy." In a paper appearing today in Science, the engineers present the design for a new ultrasound sticker — a stamp-sized device that sticks to skin and can provide continuous ultrasound imaging of internal organs for 48 hours.

The researchers applied the stickers to volunteers and showed the devices produced live, high-resolution images of major blood vessels and deeper organs such as the heart, lungs, and stomach. The stickers maintained a strong adhesion and captured changes in underlying organs as volunteers performed various activities, including sitting, standing, jogging, and biking....

From the stickers' images, the team was able to observe the changing diameter of major blood vessels when seated versus standing. The stickers also captured details of deeper organs, such as how the heart changes shape as it exerts during exercise. The researchers were also able to watch the stomach distend, then shrink back as volunteers drank then later passed juice out of their system. And as some volunteers lifted weights, the team could detect bright patterns in underlying muscles, signaling temporary microdamage.

"With imaging, we might be able to capture the moment in a workout before overuse, and stop before muscles become sore," says Chen. "We do not know when that moment might be yet, but now we can provide imaging data that experts can interpret."
They're already envisioning other possibilities: If the devices can be made to operate wirelessly — a goal the team is currently working toward — the ultrasound stickers could be made into wearable imaging products that patients could take home from a doctor's office or even buy at a pharmacy. "We envision a few patches adhered to different locations on the body, and the patches would communicate with your cellphone, where AI algorithms would analyze the images on demand," says the study's senior author, Xuanhe Zhao, professor of mechanical engineering and civil and environmental engineering at MIT.

"We believe we've opened a new era of wearable imaging: With a few patches on your body, you could see your internal organs."

"Two new studies provide more evidence that the coronavirus pandemic originated in a Wuhan, China market where live animals were sold," reports the Associated Press, "further bolstering the theory that the virus emerged in the wild rather than escaping from a Chinese lab."

CNN reports: "All eight COVID-19 cases detected prior to 20 December were from the western side of the market, where mammal species were also sold," the [first] study says. The proximity to five stalls that sold live or recently butchered animals was predictive of human cases... The "extraordinary" pattern that emerged from mapping these cases was very clear, said another co-author, Michael Worobey, department head of Ecology and Evolutionary Biology at the University of Arizona.

The researchers mapped the earliest cases that had no connection to the market, Worobey noted, and those people lived or worked in close proximity to the market. "This is an indication that the virus started spreading in people who worked at the market but then started that spread ... into the surrounding local community as vendors went into local shops, infected people who worked in those shops," Worobey said.

The other study takes a molecular approach and seems to determine when the first coronavirus infections crossed from animals to humans.... The researchers suggest that the first animal-to-human transmission probably happened around November 18, 2019, and it came from lineage B. They found the lineage B type only in people who had a direct connection to the Huanan market.
"All this evidence tells us the same thing: It points right to this particular market in the middle of Wuhan," said Kristian Andersen a professor in the Department of Immunology and Microbiology at Scripps Research and coauthor of one of the studies. The AP quotes Andersen as saying "I was quite convinced of the lab leak myself until we dove into this very carefully and looked at it much closer." Andersen said they found case clusters inside the market, too, "and that clustering is very, very specifically in the parts of the market" where they now know people were selling wildlife, such as raccoon dogs, that are susceptible to infection with the coronavirus.... Matthew Aliota, a researcher in the college of veterinary medicine at the University of Minnesota, said in his mind the pair of studies "kind of puts to rest, hopefully, the lab leak hypothesis."

"Both of these two studies really provide compelling evidence for the natural origin hypothesis," said Aliota, who wasn't involved in either study. Since sampling an animal that was at the market is impossible, "this is maybe as close to a smoking gun as you could get."
CNN notes that Worobey also had initially thought the lab leak had been a possibility, but now says the epidemiological preponderance of cases linked to the market is "not a mirage. It's a real thing.

"It's just not plausible that this virus was introduced any other way than through the wildlife trade." To reduce the chances of future pandemics, the researchers hope they can determine exactly what animal may have first become infected and how.

"The raw ingredients for a zoonotic virus with pandemic potential are still lurking in the wild," said Joel Wertheim, an associate adjunct professor of medicine at the University of California, San Diego. He believes the world needs to do a much better job doing surveillance and monitoring animals and other potential threats to human health.

An anonymous reader quotes a report from Reuters: The oldest patient yet has been cured of HIV after receiving a stem cell transplant for leukaemia, researchers reported on Wednesday. While the transplant was planned to treat the now-66-year-old's leukaemia, the doctors also sought a donor who was naturally resistant to the virus that causes AIDS, a mechanism that first worked to cure the "Berlin patient," Timothy Ray Brown, in 2007.

The latest patient, the fourth to be cured in this way, is known as the "City of Hope" patient after the U.S. facility in Duarte, California, where he was treated, because he does not want to be identified. As well as being the oldest, the patient has also had HIV the longest, having been diagnosed in 1988 with what he described as a "death sentence" that killed many of his friends. He has been on antiretroviral therapy (ART) to control his condition for more than 30 years. [...] Scientists think the process works because the donor individual's stem cells have a specific, rare genetic mutation which means they lack the receptors used by HIV to infect cells. "Scientists think the process works because the donor individual's stem cells have a specific, rare genetic mutation which means they lack the receptors used by HIV to infect cells," adds Reuters.

"After the transplant three and a half years ago, which followed chemotherapy, the City of Hope patient stopped taking ART in March 2021. He has now been in remission from both HIV and leukaemia for more than a year, the team said."

Researchers in Spain also presented a case of a 59-year-old woman who is considered to be in a state of viral remission. "She has now maintained a fully suppressed viral load for over 15 years," reports NBC News. "Unlike the handful of people either cured or possibly cured by stem cell transplants, however, she still harbors virus that is capable of producing viable new copies of itself. Her body has actually controlled the virus more efficiently with the passing years, according to Dr. Juan Ambrosioni, an HIV physician in the Barcelona clinic."

Reuters reports: The rapidly spreading monkeypox outbreak represents a global health emergency, the World Health Organization's highest level of alert, WHO Director-General Tedros Adhanom Ghebreyesus said on Saturday.

The WHO label — a "public health emergency of international concern" — is designed to trigger a coordinated international response and could unlock funding to collaborate on sharing vaccines and treatments. Members of an expert committee that met on Thursday to discuss the potential recommendation were split on the decision, with nine members against and six in favour of the declaration, prompting Tedros himself to break the deadlock, he told reporters. "Although I am declaring a public health emergency of international concern, for the moment this is an outbreak that is concentrated among men who have sex with men, especially those with multiple sexual partners," Tedros told a media briefing in Geneva.

A 37-year-old junior professor in Tennessee "identified apparently altered or duplicated images in dozens of journal articles," reports Science magazine.

But that was just the beginning for Matthew Schrag, whose sleuthing then "drew him into a different episode of possible misconduct, leading to findings that threaten one of the most cited Alzheimer's studies of this century and numerous related experiments." The first author of that influential study, published in Nature in 2006, was an ascending neuroscientist: Sylvain Lesné of the University of Minnesota, Twin Cities. His work underpins a key element of the dominant yet controversial amyloid hypothesis of Alzheimer's, which holds that A clumps, known as plaques, in brain tissue are a primary cause of the devastating illness, which afflicts tens of millions globally. In what looked like a smoking gun for the theory and a lead to possible therapies, Lesné and his colleagues discovered an A subtype and seemed to prove it caused dementia in rats.

If Schrag's doubts are correct, Lesné's findings were an elaborate mirage....

A 6-month investigation by Science provided strong support for Schrag's suspicions and raised questions about Lesné's research. A leading independent image analyst and several top Alzheimer's researchers — including George Perry of the University of Texas, San Antonio, and John Forsayeth of the University of California, San Francisco (UCSF) — reviewed most of Schrag's findings at Science's request. They concurred with his overall conclusions, which cast doubt on hundreds of images, including more than 70 in Lesné's papers. Some look like "shockingly blatant" examples of image tampering, says Donna Wilcock, an Alzheimer's expert at the University of Kentucky. The authors "appeared to have composed figures by piecing together parts of photos from different experiments," says Elisabeth Bik, a molecular biologist and well-known forensic image consultant. "The obtained experimental results might not have been the desired results, and that data might have been changed to ... better fit a hypothesis...."

Schrag's work, done independently of Vanderbilt and its medical center, implies millions of federal dollars may have been misspent on the research — and much more on related efforts. Some Alzheimer's experts now suspect Lesné's studies have misdirected Alzheimer's research for 16 years. "The immediate, obvious damage is wasted NIH funding and wasted thinking in the field because people are using these results as a starting point for their own experiments," says Stanford University neuroscientist Thomas Südhof, a Nobel laureate and expert on Alzheimer's and related conditions.

Lesné did not respond to requests for comment....

Some Alzheimer's experts see a failure of skepticism, including by journals that published the work.
Schrag has warned America's National Institutes of Health that the suspect work "not only represents a substantial investment in [NIH] research support, but has been cited ... thousands of times and thus has the potential to mislead an entire field of research."

And Harvard neurologic disease professor Dennis Selkoe told Science "There are certainly at least 12 or 15 images where I would agree that there is no other explanation" than manipulation. Selkoe's bigger worry, he says, is that the Lesné episode might further undercut public trust in science during a time of increasing skepticism and attacks. But scientists must show they can find and correct rare cases of apparent misconduct, he says. "We need to declare these examples and warn the world."
Thanks to Slashdot reader Crypto Fireside for sharing the story!

An unvaccinated young adult from New York recently contracted polio, the first U.S. case in nearly a decade, health officials said Thursday. The Associated Press reports: Officials said the patient, who lives in Rockland County, had developed paralysis. The person developed symptoms a month ago and did not recently travel outside the country, county health officials said. It appears the patient had a vaccine-derived strain of the virus, perhaps from someone who got live vaccine -- available in other countries, but not the U.S. -- and spread it, officials said. The person is no longer deemed contagious, but investigators are trying to figure out how the infection occurred and whether other people may have been exposed to the virus. The report notes that polio was declared eliminated in the U.S. in 1979, "meaning there was no longer routine spread."

Amazon is acquiring One Medical for $18 a share, an all-cash deal that values the primary health care provider at roughly $3.9 billion, the companies said Thursday. From a report: The deal deepens Amazon's presence in health care, which Neil Lindsay, senior vice president of Amazon Health Services, said is "high on the list of experiences that need reinvention."

The e-commerce giant hopes to improve how people book appointments and the experience of being seen by a physician, Lindsay said in a statement. "We love inventing to make what should be easy easier and we want to be one of the companies that helps dramatically improve the healthcare experience over the next several years," he said.

Apple published a nearly 60-page report Wednesday outlining all its health features and partnerships with medical institutions, arguing that such offerings are key to the tech giant's future. From a report: The company pointed to its breadth of existing services -- from sleep monitoring and fitness classes to atrial-fibrillation detection and cycle tracking -- and promised to build on that foundation. Chief Operating Officer Jeff Williams, who oversees Apple's health endeavors, said in a statement attached to the report that the company will continue to innovate in "science-based technology."

"The health innovations we've pioneered have aimed to help break down barriers between users and their own everyday health data, between health-care providers and patients, and between researchers and study participants," he said. The report serves as a response to Apple critics, who have knocked the company for not doing as much as rivals in health care. Though the Apple Watch dominates the market, the device hasn't always gotten novel health features as quickly as competitors' products. And fellow tech titans such as Amazon.com and Google have made ambitious forays into the medical field -- with mixed results. Apple is arguing that it's a pioneer in health technology and positioned to use it as a growth driver in the years ahead.

An anonymous reader quotes a report from Business Insider: Synchron, a brain-computer interface startup, reportedly implanted its first device in a US patient earlier this month. The startup implanted a 1.5-inch device into the brain of an ALS patient at Mount Sinai West medical center in New York on July 6, Bloomberg first reported. The purpose of the device is to allow the patient to communicate -- even after they have lost the ability to move -- by using their thoughts to send emails and texts. Bloomberg reported that Synchron has already implanted the device in four patients in Australia who have been able to use the brain implant to send messages on WhatsApp and shop online. Elon Musk's Neuralink has a similar mission, but is still waiting for FDA approval. "Neuralink and Synchron's products have several key differences: namely, size and installation," notes the report. "The Australian startup's product can be inserted into a human skull without cutting into it using a catheter that feeds the device through the jugular vein into a blood vessel in the brain. The process requires two separate surgeries."

"In contrast, Neuralink plans to make a much smaller and more powerful device that would require a portion of the individual's skull to be removed and would be performed using a robot." Neuralink also appears to be slightly more ambitious, with Musk referring to the device as "a Fitbit in your skull."

Two cases of the deadly Marburg virus have been identified in Ghana, the first time the Ebola-like disease has been found in the west African nation. From a report: Earlier in the month, blood samples taken from two people in the southern Ashanti region suggested they had the Marburg virus. The samples were sent to the Pasteur Institute in Senegal, which confirmed the diagnosis, the Ghana Health Service (GHS) said. "This is the first time Ghana has confirmed Marburg virus disease," said the GHS head, Patrick Kuma-Aboagye. No treatment or vaccine exists for Marburg, which is almost as deadly as Ebola. Its symptoms include high fever as well as internal and external bleeding. Ninety-eight people identified as contact cases were under quarantine, the GHS statement said, noting that no other cases of Marburg had yet been detected in Ghana. The World Health Organization declared Ghana's first outbreak. "Health authorities have responded swiftly, getting a headstart preparing for a possible outbreak," said the WHO regional director for Africa, Dr Matshidiso Moeti.

A new paper, published in the journal Science, found that when the Y chromosome was gone from blood cells in male mice genetically engineered to lose their Y chromosomes, scar tissue built up in the heart, leading to heart failure and a shortened life span. The New York Times reports: Because there was a direct cause-and-effect relationship between the loss of Y and ailments of aging in the mice, the study bolsters the notion that the same thing can happen in human males. Researchers have documented an increase in risk for chronic diseases like heart disease and cancer related to loss of the Y chromosome in many studies over the years, including the new one, which used data from a large genetic study of the British population. The loss of Y could even account for some of the difference between the life spans of men and women, the authors of the Science study say.

At least 40 percent of males lose the Y chromosome from some of their blood cells by age 70. And by age 93, at least 57 percent have lost some of it. The chromosome is lost sporadically from blood cells during cell division, when it is kicked out of some cells and then disintegrates. The result is what researchers call a mosaic loss of Y. There is no way, other than to stop smoking, to reduce the risk of losing the Y chromosome. And the condition is unrelated to men having lower levels of testosterone in their bodies as they age. Taking testosterone supplements would have no effect, nor would it reverse the consequences. [...]

It is too soon to say what men should do -- other than to stop smoking -- to protect themselves from losing their Y chromosomes or to alleviate the consequences. Those in [the researcher's] group found they could protect the hearts of the mice without Y chromosomes by blocking TGF-beta, a key molecule involved in the production of scar tissue. Dr. Stephen Chanock, the director of the division of cancer epidemiology and genetics at the National Cancer Institute, said the mouse study was "really cool." But he noted that there was no evidence yet that drugs to block TGF-beta would be effective in men who lost their Y. And, for now, there is little point in testing men for loss of Y, Dr. Chanock said, adding, "the over-interpretation of these data for monetary purposes worries me deeply."

Some Beijing residents returning from domestic travel were asked by local authorities to wear COVID-19 monitoring bracelets, prompting widespread criticism on Chinese social media by users concerned about excessive government surveillance. Reuters reports: According to posts published on Wednesday evening and Thursday morning on microblogging platform Weibo, some Beijing residents returning to the capital were asked by their neighborhood committees to wear an electronic bracelet throughout the mandatory home quarantine period. Chinese cities require those arriving from parts of China where COVID cases were found to quarantine. Authorities fit doors with movement sensors to monitor their movements but until now have not widely discussed the use of electronic bracelets.

The bracelets monitor users' temperature and upload the data onto a phone app they had to download, the posts said. "This bracelet can connect to the Internet, it can definitely record my whereabouts, it is basically the same as electronic fetters and handcuffs, I won't wear this," Weibo user Dahongmao wrote on Wednesday evening, declining to comment further when contacted by Reuters. This post and others that shared pictures of the bracelets were removed by Thursday afternoon, as well as a related hashtag that had garnered over 30 million views, generating an animated discussion on the platform.

A community worker at Tiantongyuan, Beijing's northern suburb, confirmed to state-backed news outlet Eastday that the measure was in effect in the neighbourhood, though she called the practice "excessive." A Weibo post and a video published on the official account of Eastday.com was removed by Thursday afternoon. Weibo user Dahongmao wrote on Thursday afternoon his neighbourhood committee had already collected the bracelets, telling him that "there were too many complaints."

An anonymous reader quotes a report from The Verge: Researchers successfully transplanted genetically modified pig hearts into two recently deceased people connected to ventilators, the New York University team announced today. The surgeries are the latest step forward in the field of animal-to-human transplants, or xenotransplantation, which has seen a flurry of successes so far this year -- raising hopes for a new, steady supply of organs to ease shortages. The only thing different about these heart transplants from a normal human-to-human heart transplant was the organ itself, the research team said in a statement.

The team performed the transplants on June 16th and July 9th, and each recipient was monitored for three days. In that time, the hearts functioned normally, and there weren't signs of rejection from the recipients, who were connected to ventilators to keep their body processes functioning semi-regularly, even after death. The two recipients were not able to be organ donors but were able to participate in whole-body donation for this type of research. The two pig hearts came from biotechnology company Revivicor, which produces genetically modified pigs (and also funded the research). The pigs had 10 genetic modifications -- four to block pig genes and prevent rejection and six to add human genes. A living person was successfully given a pig heart in early January, notes the report. While the person responded well to the transplant initially, they died of heart failure in March.

"The specific cause is still unknown, but infection with a pig virus may have contributed to his death," adds The Verge. "The pig hearts are supposed to be free of viruses, but experts say they can be hard to detect." A research paper in late June details everything that went wrong with the transplant.

Amazon is developing cancer vaccines in collaboration with the Fred Hutchinson Cancer Research Center, and it recently launched an FDA-approved clinical trial. From a report: Amazon and Fred Hutchinson are looking to recruit 20 participants over the age of 18 for the early stage, or phase 1, trial, according to a filing on clinicaltrials.gov, a database of clinical trials run by the National Library of Medicine. The goal is to develop "personalized vaccines" that can treat breast cancer and melanoma, a form of skin cancer, the filing states. Fred Hutchinson is listed as a sponsor of the study, while Amazon is listed as a collaborator, according to the filing. News of the partnership was first reported by Business Insider. The study was first posted last October, and it began June 9. It's expected to be complete by Nov. 1 of 2023. An Amazon spokesperson confirmed the partnership, and said it's being led by Fred Hutch. "Amazon is contributing scientific and machine learning expertise to a partnership with Fred Hutch to explore the development of a personalized treatment for certain forms of cancer," the spokesperson told CNBC in a statement. "It's very early, but Fred Hutch recently received permission from the U.S. Food and Drug Administration to proceed with a Phase I clinical trial, and it's unclear whether it will be successful. This will be a long, multi-year process -- should it progress, we would be open to working with other organizations in health care and life sciences that might also be interested in similar efforts."

An anonymous reader quotes a report from the BBC: In 2020 [EndeavorRx] became the first such game to be approved by the US Food and Drug Administration (FDA) for use in the treatment of ADHD in children. Currently only available on prescription from doctors in the US, EndeavorRx at first glance looks very similar to countless other games. You control a little alien that races on a spaceship through different worlds having to collect things. But the app-based game was developed in conjunction with neuroscientists, and is designed to stimulate and improve areas of the brain that play a key role in attention function. The idea is that it trains a child with ADHD to both better multitask and ignore distractions, with a computer algorithm measuring his or her performance and customizing the difficulty of the game in real time. When doctors prescribe it, the child's parents get sent an activation link that is needed before the game will play.

Eddie Martucci, chief executive of Akili, the Boston-based tech firm behind EndeavorRx, says the game has been designed to boost cognitive progressing. "It is something that's very difficult to get through molecular means, like taking a pill. But it turns out that sensory stimuli can actually directly stimulate parts of the brain controlling cognitive function." His company now plans to launch the game in Europe in the next few years. Akili is one of only a handful of companies with clearance to offer a digital therapeutic as a prescription for medical conditions. Late last year, the FDA approved a virtual reality-based treatment for children with the visual disorder amblyopia, or lazy eye.

Adding salt to meals at the table is linked to an earlier death, according to a study of 500,000 middle-aged Britons. From a report: Researchers found that always adding salt to food knocks more than two years off life expectancy for men and one-and-a-half years for women. This does not include seasoning during the cooking process. The study did not definitively rule out other factors, such as salt consumption being a proxy for a generally less healthy lifestyle, but the team behind the work said the evidence was compelling enough that people should consider avoiding seasoning their meals.

"To my knowledge, our study is the first to assess the relation between adding salt to foods and premature death," said Prof Lu Qi of Tulane University School of Public Health and Tropical Medicine in New Orleans, who led the work. "Even a modest reduction in sodium intake, by adding less or no salt to food at the table, is likely to result in substantial health benefits, especially when it is achieved in the general population." The findings were based on research involving more than 500,000 participants in the UK Biobank study, who were followed for an average of nine years. When joining the study between 2006 and 2010, they were asked, via a touchscreen questionnaire, whether they added salt to their foods and how often they did so.

Germany's BioNTech, Pfizer's partner in COVID-19 vaccines, said the two companies would start tests on humans of next-generation shots that protect against a wide variety of coronaviruses in the second half of the year. From a report: Their experimental work on shots that go beyond the current approach include T-cell-enhancing shots, designed to primarily protect against severe disease if the virus becomes more dangerous, and pan-coronavirus shots that protect against the broader family of viruses and its mutations. In presentation slides posted on BioNTech's website for its investor day, the German biotech firm said its aim was to "provide durable variant protection." The two partners, makers of the Western world's most widely used COVID-19 shot, are currently discussing with regulators enhanced versions of their established shot to better protect against the Omicron variant and its sublineages.