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Scientists Reveal World's First 3D-Printed, Marbled Wagyu Beef (interestingengineering.com) 107

Scientists from Osaka University have manufactured the world's first 3D-printed Wagyu beef by using stem cells isolated from Japanese cattle, according to a press release. The product looks like a realistic steak piece containing muscle, fat, and blood vessels. Interesting Engineering reports: Because of its high marble content, Wagyu (Japanese cow) beef is one of the most sought-after and expensive meats in the world. Marbling, or sashi in Jaoan, refers to the visible layers of intramuscular fat that give the beef its rich flavors and distinctive texture, and because most cultured meats produced thus far resemble mince composed of simple muscle fibers rather than the complex structure of real beef steaks, 3D printing Wagyu is an extremely difficult feat.

The researchers used two types of stem cells, bovine satellite cells and adipose-derived stem cells, insulated from Wagyu cows, according to the paper published in the journal Nature Communications. Then, they incubated and coaxed the cells into becoming the various cell types required to generate individual fibers for muscle, fat, and blood vessels. These were piled into a 3D stack to resemble the marbling of Wagyu. Then, the researchers adapted a technique inspired by the one used to produce Japanese Kintaro candy, an old traditional sweet formed in a long pipe and cut into slices. The stacks were sliced perpendicularly to form lab-grown beef slices, which allowed a great degree of customization within the complex meat structure. This was how they were able to mimic the famous texture of Wagyu. According to the researchers, the synthetic meat "looks more like the real thing" and the process can be used to create other complex structures.

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Scientists Reveal World's First 3D-Printed, Marbled Wagyu Beef

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  • by rossdee ( 243626 ) on Thursday August 26, 2021 @10:15PM (#61734365)

    Generate less greenhouse gas than raising a real cow?

    • Depends upon how the cells are "fed" and if the workers are lactose-intolerant.

    • Re:Does this (Score:5, Interesting)

      by PinkyGigglebrain ( 730753 ) on Thursday August 26, 2021 @11:20PM (#61734445)

      interesting fact about the cattle CO2/methane issue

      For millions of years there have been ruminates on Earth, sometimes with populations that matched or exceed today's number of cattle, for example just the Bison in the USA had populations ranging from 30-60 million head before they almost got wiped out in the mid 1800s. And yet during all that time the CO2 and methane levels in the atmosphere were fairly stable.

      And yet somehow cattle are now to blame for a large portion of the CO2 and methane being added into the atmosphere annually [cornell.edu]

      • Nobody's blaming the cattle, I'm sure they would prefer to not be turned into tasty hamberders.
      • Cattle are bad for the environment if you're slashing and burning to create a manmade cow field. Environmentalists who have a cow over cow farts and burps are being idiots, though. Any plant matter a cow eats is already part of the natural carbon cycle, and would've eventually rotted and released methane regardless of whether or not it ultimately became a meal for a bovine.

        • I'm trying to follow this logic. Plant matter rotting in a swamp would produce methane I suppose. Do you think cows graze in swamps?
        • and released methane

          You only get methane if it decomposes in a low-oxygen environment. The vast majority of what a "wild cow" would eat would decompose on the surface if it wasn't eaten, and so be reduced to CO2 instead of methane.

        • Interesting fact. Grain fed cows create more methane and their meat is higher in saturated fats than grass-fed beef. And grass-fed, imo, tastes better than just organic beef fed from organic grains. Just feed the cow what they want to eat anyway. And dont get me going on grass-fed created butters. Kerrygold and other irish butters taste miles ahead of plain old organic butter.
      • Re:Does this (Score:5, Informative)

        by ArchieBunker ( 132337 ) on Friday August 27, 2021 @07:21AM (#61735003)

        Lol that's an op-ed piece you linked to. He doesn't offer any real data to back his claim. Also cattle are fed corn because it's cheap when they evolved eating grass. Adding some seaweed to a cow's diet can reduce their methane emissions by 82%. https://www.smithsonianmag.com... [smithsonianmag.com]

        • by kbahey ( 102895 )

          According to Our World In Data [ourworldindata.org] livestock and manure make up only 5.8% of total greenhouse gases.

          So cows alone cannot help, whether people advocated going vegan, or feeding them seaweed.

          Other sectors have much more share, and therefore addressing them for GHG reductions, will have more impact: examples are: energy and transportation.

      • For millions of years there have been ruminates on Earth

        So what?

        And yet during all that time the CO2 and methane levels in the atmosphere were fairly stable.

        Cows are different.

        New things can be different.

        HTH, HAND

      • Then humans discovered oil. CO2 and methane levels would never be stable again.

    • The question is important, but not even the most critical. Even if carbon footprint would actually be lower (which I don't believe - not if you're looking to make the same quality meat as nature without cutting corners), it would still be a bad idea to continue down this path.

      The problem is much deeper: right now our planet literally grows all the food we need, inclusing essential proteins in the form of meat.

      If you feel like it, and you have even a few square feet of a yard, you can grow meat, e.g. chicken

      • Many people do not have a back yard. Others who might have a yard still don't grow their own meat. They already get it from Big Ag or similar.

        • Yes, that's true. And sad, as this already degrdes the quality of food, on global average. The mere existence of Big Ag is already a problem. Verical Farming hobbies in urban areas are starting to become a thing for a reason.

          But this doesn't invalidate my argument. Just imagine what the world looked like if *only* Big Ag would have any possibility to exist. And then extrapolate and guess how Meat-InA-Lab, Inc. would look like, and whether it would be Big or not.

          • Yes, that's true. And sad, as this already degrdes the quality of food, on global average. The mere existence of Big Ag is already a problem. Verical Farming hobbies in urban areas are starting to become a thing for a reason.

            It's actually fun to grow your own food. My wife and I carry on my parents annual ritual of canning food. Some is grown by us, some is purchased. Corn for instance, needs more space than we have. And we have a provider that let's us get corn picked at dawn, blanched and into the can or some frozen within hours.

            Same with sausage, bacon, and various charcuterie. We don't do our own butchering though.

            But it's a hobby for certain. And you must adhere to some pretty strict sanitation protocols.

            That last is

            • Seems like we're largely on the same page here.

              But for love of me I can't understand where your trust in food industry comes from. By definition they're out to cheat you at the very essentials of life - eating. After all, they need not only provide you with food, but also themselves with profits.

              But let's forget about motivation and watch the track record: we have massive issues with monocultures and with soil erosion precisely because of the food industry and industrial farming. Same with over fertilizatio

              • Seems like we're largely on the same page here.

                But for love of me I can't understand where your trust in food industry comes from. By definition they're out to cheat you at the very essentials of life - eating. After all, they need not only provide you with food, but also themselves with profits.

                It isn't that it's trust. It's just that I strike a compromise ground between the folks that always eat out and are consuming gawd knows what, and a total subsidence farming life on the other end of the scale. I do what I can, buying local - although you still gotta check the creds, we have a lot of "Amish" farm market sellers that drive to and from their stands, and their daughters that help out occasionally don't get all their makeup removed. Food stand theater!

                So I do what I can, coming from a family

          • For most of us, we live in a world where only Big Ag has any possibility to exist.

            No farm to table/locally produced.

            No homegrown.

            Just Big Ag.

            For that audience, vat grown animal flesh is not going to be a downgrade. If the printing tech becomes sufficiently ubiquitous, you can "grow" your own with feed stock and the proper blueprints, which will probably be leaked online soon enough.

            • I understand your hope, but I'm highly skeptical. Pretty much like you don't make your own baby milk, although all you need is cow milk amd a pyrolithic installation.

              Growing a sack of potatoes or enough tomatoes to get you through most of the season on a balcony is alreay easy enough. All you need is literally 1 sqft of ground and a few gallons of dirt. It doesn't get any easier than than. Yet most of the people you refer to don't do it.

              Guess we'll live and see.

      • Re: Does this (Score:5, Interesting)

        by damn_registrars ( 1103043 ) <damn.registrars@gmail.com> on Friday August 27, 2021 @07:51AM (#61735057) Homepage Journal
        I think you're missing the real advantage here.

        If we can start to grow meat in the lab (and later factory) without raising the animal, the meat could actually become less expensive relative to its current cost.

        The reason for this is two fold. One, when we raise an animal there is a fair bit of it that is thrown away (certain organs for example) or not edible at all (most bones for example). Yeah some of this gets used in other ways but some just ends up going to waste entirely - this makes the meat more expensive as feed still goes in to the animal to produce these parts that we do not - or cannot - eat.

        Second, the cost of meat is also dependent on the cost of animal feed. We all hear about how many crops are raised just to feed animals. Meat produced in a lab or factory won't need the same nutrition as an entire animal, which will make more crops - and crop lands - available for human consumption. Again this can eventually bring down the cost of producing meat as we can scale up processes to produce the serums that we need for that.
        • I understand the arguments, I just don't trust them - on several levels.

          First, the energy argument: how much exactly do you need to grow, say, a goat? Most of it is plants that grow using 100% renewable energy, no downsides whatsoever. Been using for millenia. Energy that is harvested and converted by bacteria and biochemical processes optimized by evolution for millenia.

          We also know how sensitive the quality of meat already is to factors like quality of animal food, space in which the animals grow etc. Mo

          • *reeks of buzzword-bingo style of cheap marketing.

          • Most of it is plants that grow using 100% renewable energy, no downsides whatsoever.

            Except we don't have those animals graze on wild pasture land. We farm the food, with tractors and fertilizer and such, which isn't done with renewable energy. Then we also ship that food to the animals. Again, not renewable.

            Plant -> human is also more efficient than plant -> goat -> human. Goats do things like "produce heat" and "move", so a lot of the calories from the plants are lost before the meat ends up in your fridge.

            (Obviously plants for human consumption would be different than plants

            • Except we don't have those animals graze on wild pasture land. We [...] Again, not renewable

              Agree to all of that. But then that is our problem, and we should try to fix that, instead of trying to come up the cluster fuck of even more industrial food preparation, with a myriad more problems of its own.

              Plant -> human is also more efficient than plant -> goat -> human.

              Yes, and photosynthesis -> human is even more efficient, only limping on the minor detail that we're not cut out for photosynthesis. We're also not cut out for a plant-only diet. We can go a long way, admittedly (a lot longer anyway than on photosynthesis), but we're meant to eat meat, too.

              Goats do things like "produce heat" and "move", so a lot of the calories from the plants are lost before the meat ends up in your fridge.

              They als

              • Agree to all of that. But then that is our problem

                Then you vastly increase the energy required for transportation of the herd. Which today is not going to be a months-long cattle drive across the country, it's gonna be a semi.

                Also, not enough prairie if you want to actually feed everyone.

                Yes, and photosynthesis -> human is even more efficient, only limping on the minor detail that we're not cut out for photosynthesis.

                No, the "minor detail" is you can't collect enough energy from the sun and do things like "think" and "move". A large tree collects about 200 calories a day.

                More to the point, bringing up impossible hypotheticals doesn't change that removing the produce an animal step is

                • You keep parroting things which are simply not true and base your arguments on them. Here's one example:

                  Also, not enough prairie if you want to actually feed everyone.

                  Show me your numbers.

                  Back of the envelope calculation tells me: 1 cow feeds 10 people a year. 10 bn pepole, 1 bn cows, 1 hectare per cow, makes about 10 mio sq km for the entire world population. Make it a factor of 2, 3, 5x that if you need to, but you don't have to.

                  As to the transport problems: way to go in building up denial. See, nobody forces you to put all the cows in one place, and all the people s

      • Do you really think that humanity isn't largely reliant on corporations for food now? Do you really think the average New Yorker knows a god damn thing about raising a chicken, or growing vegetables?

        • Yes to the 1st question.

          No to the 2nd: the typical NY'er doesn't know how to grow a chicken, but I assure you that, appart from internal psychological reservation regarding killing said chicken, a 5 min youtube video can teach him everything he needs to know. Make it 1 minute if you're in a hurry. Make it 10 seconds if your life depends on it. (Actually, if your life really depends on it, you'll figure it even without anyone telling you by noon; pro tip: of a chicken, you can eat everything your teeth are s

        • Comment removed based on user account deletion
  • by RightwingNutjob ( 1302813 ) on Thursday August 26, 2021 @10:17PM (#61734369)

    it all ends up the same in the end...

  • According to Wikipedia, back in 1931 Winston Churchill wrote an essay titled Fifty Years Hence that had the following excerpt
    âoe We shall escape the absurdity of growing a whole chicken to eat the breast or wing, by growing these parts separately under a suitable medium. âoe

    So far it has been a challenge though. Theoretically it should be totally possible, but probably needs a few billion dollars in research.

  • by bobstreo ( 1320787 ) on Thursday August 26, 2021 @11:06PM (#61734425)

    As always:

    How does it taste?

  • by jfdavis668 ( 1414919 ) on Thursday August 26, 2021 @11:14PM (#61734433)
    I don't have time for this one.
  • Give me a real porterhouse steak!
  • the beef wags you.

  • by DrXym ( 126579 ) on Friday August 27, 2021 @04:20AM (#61734789)
    ... it's not marbled wagyu beef. What they've made, is a decorative meat slurry.
    • by AmiMoJo ( 196126 )

      Compared to much of the available astronaut food though it's probably quite welcome for future Mars settlers.

      This is an encouraging step towards high quality synthetic meat that could allow us to eat lots of it and meet climate change targets. Of course it needs work but it shows that it's at least possible to produce something approaching high quality beef in a lab.

  • You can leave out the blood vessels, wtf.

    Fat, however, is a necessity. Cooked meat itself is rather pointless without it. Try making a hamburger from steak tartar. You'll be running for a slice of cheese in anger.

    Raw (like the steak tartar), or rare meat, is a different story, though the latter benefits from warmed fats too.

    • Re: (Score:1, Interesting)

      by BAReFO0t ( 6240524 )

      In Germany we eat raw pork mince on beat too. It's called "Mett", and isn't lean at all. But it's delicious! (Eat with lots of raw onion on top, and butter below, on a nice crispy bead roll half.)
      So I can confirm that fat in raw meat is tasty too.

      And we can do that without worry, by the way, because by law, every piece of meat has to be inspected by a veterinarian (e.g. for hook worms) before it is allowed to be sold. Called "Fleischbeschau', That became law after people died from trichinosis I think it is

    • You can leave out the blood vessels, wtf.

      Fat, however, is a necessity. Cooked meat itself is rather pointless without it

      Ain't that the truth. My MIL was trying to eliminate as much fat from her diet as possible during the days of "All fat is Bad!!"

      There was a thing to do where you cooked and crumbled hamburger down to not quite the browned stage, drain the fat, and than put it in a colander and pour boiling water over it to remove the rest of it.

      I sampled some. Cardboard tastes better than that.

  • But what I care about is "tastes and feels real". The story does not mention either. Because if it is only about looks, this can be printed from something else entirely.

  • Wagyu? I barely know yu.

  • Um I'll have the Brittany Burger please http://bitelabs.org/ [bitelabs.org]

  • I don't know which is more highly processed: computer-generated beef or all-vegetable so-called "Impossible meat". In either case, highly processed foods are unhealthy.

    As my brother once asked: "If we are not supposed to eat animals, why are they made out of meat?"

  • The description sounds yummy

The most exciting phrase to hear in science, the one that heralds new discoveries, is not "Eureka!" (I found it!) but "That's funny ..." -- Isaac Asimov

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