A New Type Of COVID-19 Vaccine Could Debut Soon (npr.org) 148
"A new kind of COVID-19 vaccine could be available as soon as this summer," reports NPR:
It's what's known as a protein subunit vaccine. It works somewhat differently from the current crop of vaccines authorized for use in the U.S. but is based on a well-understood technology and doesn't require special refrigeration.
In general, vaccines work by showing people's immune systems something that looks like the virus but really isn't. Consider it an advance warning; if the real virus ever turns up, the immune system is ready to try to squelch it. In the case of the coronavirus, that "something" is one of the proteins in the virus — the spike protein. The vaccines made by Johnson & Johnson, Moderna and Pfizer contain genetic instructions for the spike protein, and it's up to the cells in our bodies to make the protein itself.
The first protein subunit COVID-19 vaccine to become available will likely come from the biotech company, Novavax. In contrast to the three vaccines already authorized in the U.S., it contains the spike protein itself — no need to make it, it's already made — along with an adjuvant that enhances the immune system's response, to make the vaccine even more protective.
Protein subunit vaccines made this way have been around for a while. There are vaccines on the market for hepatitis B and pertussis based on this technology.
And meanwhile, the article points out, there's also another company — the pharmaceutical giant Sanofi — that's also working on its own protein subunit vaccine against the coronavirus.
In general, vaccines work by showing people's immune systems something that looks like the virus but really isn't. Consider it an advance warning; if the real virus ever turns up, the immune system is ready to try to squelch it. In the case of the coronavirus, that "something" is one of the proteins in the virus — the spike protein. The vaccines made by Johnson & Johnson, Moderna and Pfizer contain genetic instructions for the spike protein, and it's up to the cells in our bodies to make the protein itself.
The first protein subunit COVID-19 vaccine to become available will likely come from the biotech company, Novavax. In contrast to the three vaccines already authorized in the U.S., it contains the spike protein itself — no need to make it, it's already made — along with an adjuvant that enhances the immune system's response, to make the vaccine even more protective.
Protein subunit vaccines made this way have been around for a while. There are vaccines on the market for hepatitis B and pertussis based on this technology.
And meanwhile, the article points out, there's also another company — the pharmaceutical giant Sanofi — that's also working on its own protein subunit vaccine against the coronavirus.
Mixing (Score:2)
Can we mix it with other vaccines, as some governments insist on doing?
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Can we mix it with other vaccines, as some governments insist on doing?
I wouldn't want to mix it, as injecting Covid vaccine and a flu vaccine simultaneously, because your body might react too strongly. Or not strong enough. But i haven't seen anyone suggesting this.
There seems to be no reason not to get two different vaccines, with a reasonable gap between both injections. They all result in spike proteins being in your body, and your body creating defenses against anything with these spike proteins. How the spike protein got there would be irrelevant.
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Can we mix it with other vaccines, as some governments insist on doing?
I wouldn't want to mix it, as injecting Covid vaccine and a flu vaccine simultaneously, because your body might react too strongly. Or not strong enough. But i haven't seen anyone suggesting this.
If you haven't seen anyone suggesting this, you didn't look hard enough. For just one example, Moderna CEO Stephane Bancel was interviewed in April [cnbc.com]:
Johnson & Johnson is not an mRNA vaccine (Score:5, Informative)
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There's a lot of confusion, and I'm not sure which is which. mRNA vaccines require three parts to carry it - the mRNA strand, a protective fatty blob to protect the RNA strand, and a material that will get the cell to accept it. So an mRNA vaccine infects the cell and the cell's mechanism manufactures the spike protein.
Now, I've heard different ways the AZ and J&J vaccine work. One way is that the adenovirus is co
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Both AZ and JJ use the adenovirus to carry DNA into the nucleus, which then makes the mRNA that goes to the cytoplasm where the spike protein is made. The DNA remains apart from the chromosomes. Neither have spike proteins on the adenovirus. Furthermore, the adenovirus vector is replication deficient and cannot spread or infect the human host beyond the amount delivered in the dose.
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You are correct that the J&J is not an mRNA vaccine, but the summary never said it was. All it said is that the 3 vaccines "contain genetic instructions for the spike protein", which is true for both mRNA vaccines and adenovirus-based vaccines.
J&J vaccine does not contain any genetic instructions (=mRNA), but a full adenovirus with COVID's spike attached to it.
Stuck in the approval process (Score:2)
The trial was completed months ago but approval is still being withheld. Is this because they're being paranoid about 'new stuff'?
[Full disclosure: I was part of the UK phase 3 trial for this - got the placebo which I discovered when I was offered another vaccine as part of our roll out, so I feel like I've got a stake in this!]
Separate trial per country (Score:2)
I'm guessing a trial for use in each country (or multi-country economic area) needs to be done on that country's soil, as each country's population has a different mix of variants.
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Not what this report of others' experience shows. (Score:2)
The Bloomberg Covid vaccines data page shows the approval process for all the ones in play at the moment. Novavax is stuck in the 'Yellow' category far longer than any other for no apparent reason.
About 3/4 of the way down the page
https://www.bloomberg.com/grap... [bloomberg.com]
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2 classes of vaccine (Score:3)
There are 2 basic classes of vaccine for a century or more.
1.Vaccines that contain the actual antigen in large quantities, often with adjuvents to promote a strong immune response. This was originally killed inactive cultured virus, but this article is the new class where just an antigen is cultured and purified. It's more sophisticated and pure, but both have the same problem, the antigen comes in on the injection, and no more will be available till another dose. Therefore adjuvants that maximise the immune response are very important.
2. Virus like carriers. Which could be attenuated virus that isn't deadly, or a virus that is very close to the virulant virus. This goes all the way back to cowpox vaccines for smallpox with Jenner. These infect the body, produce antigen by the bodies cells and induces an immune response. The production of antigen is long lived (days) so do not need adjuvants like above. The new generation are mRNA vaccines (Moderna and Pfizer), that smuggles some copies of the mRNA for an antigen into cells to produce that for a short time. It isn't infectious and it doesn't get incorporated into genomes, just produces the antigen. Similarly, AAV vaccines (AZ and the Russian one) use an engineered attenuated virus that isn't related to the target virus to essentially do the same.
Both have advantages and disadvantgeuos, but a year ago the cultured antigen with standard adjuvant like being discussed here seemed to be the most likely to get through into the clinic. Most well understood mechanism, and a biopharma manufacturing already well setup to deliver this. But the mRNA and AAV's both won.
A new kind of COVID-19 vaccine? (Score:2)
Calling it 'Novavax' is a bit on the nose, innit?
I don't get how this is different from AstraZeneca (Score:4, Informative)
Amazingly the article doesn't even mention the AstraZeneca vaccine as if it doesn't exist, which already does exactly this:
"The Oxfordâ"AstraZeneca COVID-19 vaccine is a replication-deficient simian adenovirus vector, containing the full-length codonâoptimised coding sequence of SARS-CoV-2 spike protein along with a tissue plasminogen activator (tPA) leader sequence."
Source: https://en.wikipedia.org/wiki/... [wikipedia.org]
Just like this proposed vaccine, it is very popular with less-developed countries as it keeps at normal refrisgerator temperatues isntead of needing specialized -70C freezers. Probably around a billion doses given so far, including myself. The EU has 400 million allocated.
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You misunderstood this "new approach".
It has nothing to do with the AZ vaccine or others.
Definitions:
Antigene - the thing in your blood and body that
a) makes the immune system nervous
b) makes the antibodies dock on and attempt to block them from entering a cell
Antibody - see above, the thing the immune system (amoung other things) needs to build to defend against the infection
- those antibodies bind to antigenes
Normal vaccines one way or the other:
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The coding sequence is not the protein (Score:2)
optimised coding sequence of SARS-CoV-2 spike protein
The coding sequence for the protein is not the protein, though.
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It's different because the protein is ready-made where the AZ vaccine uses a nerfed virus to make the protein on site.
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Novavax has shown strong efficacy in trials. It's 96% effective against the native Wuhan strain, 86% against the UK strain, and 55% against the South African strain. There were no deaths or hospitalizations in any of the vaccinated participants. Notably, AZ isn't effective against the SA strain.
https://ir.novavax.com/news-re... [novavax.com]
Garbage reporting (Score:2)
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mRNA vaccines versus subunit vaccine paper (Score:2)
This was a different protein vaccine tested. The results might not be the same. But for this one, the results were that the mRNA vaccines lit up whole parts of the immune system better than the protein vaccine:
https://www.cell.com/immunity/... [cell.com]
Just guessing, I don't have science behind me here, but it's conceivable that the mRNA vaccines causing a few days of protein synthesis are closer to what the immune system evolved to counter than a single short dose of protein and adjuvant.
Or maybe the new one will wo
Dang this is clever! (Score:2)
How it's functionally different from an inactivated virus is the part I don't get, but hot damn it's ingenious.
It's not paranoia if they're out to get ya... (Score:2, Interesting)
https://redstate.com/jenvanlaa... [redstate.com]
"A person believed to be among the highest-ranking defectors ever to the United States from the People’s Republic of China has been working with the Defense Intelligence Agency (DIA) for months, sources inside the intelligence community have told RedState on condition of anonymity. The defector has direct knowledge of special weapons programs in China, including bioweapons programs, those sources say."
"RedState’s sources say that’s partially true. FBI Direc
Fauci's emails and more vaccine info... (Score:2)
https://www.icandecide.org/ [icandecide.org]
If what I had early last year was the Covid, I'm not impressed as a 50+yo lifelong smoker. I had a bug in the summer of '17 that was WAY worse.
If you're trusting that TPTB, Big Pharma, Big Tech and the MSM are there to inform and protect you, you deserve what you get. Even the Founding Fathers tried to warn you about what invariably happens to societies...
Don't get in the way of $ lovers... (Score:2)
https://www.globalresearch.ca/... [globalresearch.ca]
CPSO commands Ontario’s doctors not to make any statements that might be considered anti-vaccine, anti-masking, anti-distancing, or anti-lockdown. It forbids them to promote “unsupported, unproven” treatments for COVID-19. (Unproven by what standards? CPSO doesn’t say.) Doctors are further forbidden to make comments that might encourage people to act contrary to public health orders.
Finally, there’s a naked threat: say the wrong thing and you
CDC/VAERS reporting analysis (Score:2)
https://21stcenturywire.com/20... [21stcenturywire.com]
https://vaers.hhs.gov/data.htm... [hhs.gov]
Mark Twain (Score:2)
âoeIt's easier to fool people than to convince them that they have been fooledâ --Mark Twain (b. 1835)
Re:So like prions? (Score:5, Insightful)
Totally unlike. Prions are an unusual class of proteins with very special properties. The spike protein is not a prion and has nothing to do with them.
Re:So like prions? (Score:4, Insightful)
Because I trust my body
The worst kind of stupidity is the kind where the stupid person thinks they know something.
Re:So like prions? (Score:4, Insightful)
Let's not delude ourselves, given your demonstrated understanding of ... well ... everything we've ever discussed on Slashdot, no one here would have mistaken you for someone who has a clue about vaccines.
Re: So like prions? (Score:2)
Can you elaborate on that?
Re: So like prions? (Score:5, Funny)
Can you elaborate on that?
cat /dev/random > slashdot.org
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My cats would never do that!
Re: So like prions? (Score:2)
Not particularly, but I like to read of on some of the more out there conspiracies I see.
I've literally never heard this one before, so I was curious what I'd get back. I wasn't even able to Google it.
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Not particularly, but I like to read of on some of the more out there conspiracies I see.
I've literally never heard this one before, so I was curious what I'd get back. I wasn't even able to Google it.
Starting at 0 is a sign I state unpopular things, not that I'm a troll. It was spring of last year I read about the stuff but I don't recall precisely wear, I believe it was China and either South Korea or Singapore which were attempting to vaccinate coronavirus strains which impacted farm animals, they attempted it several times over the course of half a decade with mRNA vaccines and the result was sterility or death within 3 generations of the vaccinated animals.
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Yes, agreed.
It's a sign that you state insanely unpopular things. Also a little bit of nonsense. Like what does death 3 generations later mean? most humans are dead 3 generations later too, and also all human great-grandchildren are expected to die.
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I'm 99.99% sure that's a misunderstanding of the science. The research I've seen says that it can bind with prions, not that it acts like a infectious prion (i.e. causes other proteins to start folding incorrectly).
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... and mentions '100% mortality of inoculated germlines within 3 generations' as though that statement either made any sense, or was anywhere near how these sorts of experiments are designed.
That's an understatement. Most of the animal tests end with subjecting the animal to the actual virus and then killing the animal and dissecting its lung tissue or whatever to see the effect. So there's 100% mortality long before 3 generations, and it's not because of the vaccine. :-)
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Fascinating, that definitely doesn't mention any sterility in 3 generations, but it is a neat article.
Re:Great news (Score:5, Informative)
but they have not been proven safe to the degree that most vaccines have.
Most vaccines are highly custom created each using different delivery mechanisms which are themselves unproven. Each of these "traditional" ways we have vaccinated people comes with their own individual and unique unknowns and risks which are evaluated during the development phase. There's nothing about them which makes them "safer" in the all inclusive and lumped together sense of the word. Each vaccine developed has unique and different makeups of antigens, viral vectors, or attenuated viruses which require careful study as their effects are unknown on the body.
The new vaccines "what big tech keeps pushing" on the other hand use mRNA literally injecting into your body something that already is part of your body's natural process. We have been playing with mRNA for 40 years. COVID-19 is definitely not the first time it has been injected into a human body, we've been injecting these into our bodies for 20 years as part of various trials for treating forms of cancer and other non-viral diseases. The only thing unique or "new" here is that we're using it as a vaccine. The reason it was "pushed" is because it was able to be developed extraordinarily quickly due to the nature of how it works making it a best contender to stop a pandemic. And now to the kicker:
Among immunologists the mRNA is considered the safest vaccine ever created as it is the only vaccine ever developed where 100% of the components were known quantities in regard to how the body handles them. The only unknown was how much mRNA is required for T-cells to be produced.
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Clotting problems were found with the adenovirus vaccines, not the mRNA vaccines. The mRNA vaccines had different problems: they provoked anaphylactoid reactions in very rare instances, but the reactions can be easily managed.
It's definitely jumping the gun to say mRNA vaccine components *were* entirely known quantities. But at this point something like a billion doses of mRNA COVID vaccines have been administered, with an excellent safety record. Instances of *severe* allergic reactions are on the order
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Regarding "easily managed" - to my knowledge there is no treatment for GBS. Fortunately, it is astronomically unlikely to result in GBS. I think after hundreds of millions of dozes administered there are less than 1000 cases worldwide.
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Well, plasmapheresis can help, as can antibody treatment.
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For example, mechanisms behind rare risk of blood clots was not know up until very recently.
The current mRNA vaccines do not have that effect. Only AZ and J&J seem to be affected. And current research suggests this has to do with protein contaminations from the manufacturing process, that should not be in the vaccine.
Latest studies showed that mRNA has multi-year (maybe multi-decade) effectiveness
There is no such study. The world first mRNA vaccine started human trials December 2020. That is a single ye
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For example, mechanisms behind rare risk of blood clots was not know up until very recently. The current mRNA vaccines do not have that effect. Only AZ and J&J seem to be affected. And current research suggests this has to do with protein contaminations from the manufacturing process, that should not be in the vaccine.
Only one of them contains EDTA, so if that's the cause for the AZ vaccine's clotting problems, then the J&J vaccine has a separate problem with the same effect. Odds are, there's a single common cause, and the most likely common factor is that they both use an adenovirus vector. Adenoviruses attack platelets, and for some reason, damaged platelets cause other platelets to clump.
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Not sure, if shooting spike proteins only in the bloodstream are less experimental than mrna which has been in research for 30+ years now.
The proven method would be a dead virus injection, and those vaccines also exist.
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The bits that your body built that look like a Covid virus last a bit longer, but that's something this new vaccine here also puts into your body. So there is just some tiny step in between.
Then there's the stuff containing
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Correct. They've been proven safe to a Dramatically higher extent due to some of the larges stage 3 trials in human history.
Between 30K-40K seems to be going rate for the covid vaccine Stage 3 trials, something almost unprecedented in previous vaccines.
And the end result was we found them extremely safe.
Re:Great news (Score:5, Informative)
basically a gene mod
Fuck you and your lies. That is not how any of that works, not basically, not at all. The only crime is you posting that bullshit. What kind of sick mind tries to keep people from getting vaccinated?
Not necessarily "sick" (Score:2)
It might be somebody collecting an unethical paycheck. Although I will question the wellness of anyone who helps COVID continue to propagate. I would have less contempt for someone whose crime was stealing catalytic converters.
We know there's at least one paid anti-vax effort:
https://www.connexionfrance.co... [connexionfrance.com]
How many more? How many people on social media took the money?
Re: Great news (Score:5, Insightful)
By "vaccinating" you mean sterilized, you stupid fuck with no argumentative proof to the contrary.
And your proof for extraordinary claim about sterilization is...? That's what I thought, nothing.
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Re: Great news (Score:5, Insightful)
By "vaccinating" you mean sterilized, you stupid fuck with no argumentative proof to the contrary.
That which can be asserted without evidence, can be dismissed without evidence.
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That which can be asserted without evidence, can be dismissed without evidence.
You really should have a mod point for that, but I have none.
Instead, I will ask, would it be going to far to modify your statement?
That which is asserted without evidence should be dismissed without evidence.
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That which is asserted without evidence should be dismissed without evidence.
Nope. FTFY:
That which is asserted without evidence will be dismissed without evidence.
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I like that.
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Or, to modify a great quote from abolitionist William Lloyd Garrison,
With reasonable people I will reason. With humane people I will plead. To liars I will give no quarter, nor waste arguments on them.
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Reckless and malicious speech must be addressed (Score:3)
By "vaccinating" you mean sterilized, you stupid fuck with no argumentative proof to the contrary.
Yelling "FIRE!" in a crowded theater is reckless and malicious speech. Your anti-vax statements are equally reckless and malicious speech.
You can choose to put yourself at risk for whatever you want. However, your freedom to choose for you does not mean you can choose to put society at large at risk, as you do when you choose to not be vaccinated sans legitimate medical reasons. You can expect to be identified and to have your rights gradually reduced until complete isolation. Or, you can choose to isol
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One doesn't have to provide "augmentative proof" against a proposition presented without proof.
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An inoculation causes a fever. It is a normal body reaction for a female to cancel the current cycle if the body "believes" an infection is going on. Would not make any sense to carry a clump of cells in your womb that can not be reached by the immune system to be protected if something evil is roaming in the body of the mother.
Astonishing what mother nature figured out itself, isn't it?
Re:Great news (Score:5, Informative)
The mRNA stuff is basically a gene mod, which has been tried in animals in the past, always resulting in absolute mortality or sterility within 3 generations
mRNA has been tested on animals for over 30 years with precisely none of the results your anti-vax lying bullshit claims.
Please STFU before you get others killed.
Re:Great news (Score:5, Informative)
Also, the mRNA doesn't enter the cell nucleus. It doesn't tamper with our genetic code. Instead, it enters the outer area of the cell and gets the cell to pump out spike proteins in the same way the COVID-19 virus would get our cells to pump out new versions of itself. Once the mRNA's job is done, it's broken down. The only "trace" of the mRNA vaccine in your body after a few weeks are the immune system's memory cells which are now primed to recognize the COVID-19 virus (or, more accurately, its spike proteins). Our genome isn't altered and we don't pass any changes to our children.
Re:Great news (Score:4, Insightful)
I think its important to also mention that when stating that the mRNA vaccines do not enter the nucleus, in order to pre-empt the antivaxxers argument.
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You misunderstand or misrepresent.
It's true there was a mention of an early attempt at an mRNA based vaccine that would compromise one cells genetic machinery, but that was quickly dropped. And the only way it would have spread would be via cancer. (One guess I made about the reason it was dropped is that insertions into the genetic machinery have a tendency to cause cancer...but that was a guess.) IIRC, that attempt at a vaccine never even reached the phase I tests in humans. I only heard about it in t
Urgent request (Score:2)
Please continue posting your lies on a nerd site where people read things and know better. That way you still get paid but you're far less likely to get people killed.
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The mRNA stuff is basically a gene mod,
No it is not, for that you would need to change the DNA (and for a vaccine that makes no sense as it would lead to endless production of the antigene)
which has been tried in animals in the past
This is a lie - see above. It makes no sense to put a vaccine into your DNA.
, always resulting in absolute mortality or sterility within 3 generations (for other forms of coronavirus, at that.)
This is utterly dumb.
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The mRNA stuff is basically a gene mod, No it is not, for that you would need to change the DNA (and for a vaccine that makes no sense as it would lead to endless production of the antigene)
Yeah, it is. All genes do is code for when and what proteins to make. If you're bypassing that system it's functionally identical other than the fact it doesn't necessarily pass generationally via gametes, except for the fact in this case it's been known to be taken up by gametic cells, so it does that too.
which has been tried in animals in the past
No, it is not. It was tested in east asia on farm animals with different strains of coronavirus over the course of years. It resulted in 100% sterility or death within 3 generations every time. The research on this was being passed around over a year ago when they first started discussing the use of an mRNA vaccine.
This is a lie - see above. It makes no sense to put a vaccine into your DNA.
I agree, it also makes no sense to tell your cells to print off spike proteins in order to vaccinate against a virus as in an mRNA, you can just inject the proteins themselves once as TFA is talking about doing and leave the synthesis of the proteins themselves to engineered microbiological organisms or plants as, again, TFA this comment chain is in reference to is about. Not that that's necessarily an agreeable thing in itself, as in the case of the novel coronavirus it's actually the spike proteins which cause the overwhelming majority of the damage in the first place. At least if you got the virus your body could kill it off, if you get the mRNA vaccine it keeps your body pumping out those spike proteins for as long as the transfected cells exist within you.
This is utterly dumb.
Agreed.
Re:Won't matter to politicians in the UK (Score:5, Insightful)
appears to be on a power trip and doesn't want to give up its new authority based on mere science
The science says to keep wearing masks until a pandemic is over. Deaths are down in the noise, correct. Now tell us all why you propose killing people unnecessarily while a pandemic is still very much ongoing?
Are you that fucking impatient?
Re: Won't matter to politicians in the UK (Score:2)
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The science also shows that the numbers from outdoor exposure are so immeasurably small, that to the extent that mask wearing outdoors is entirely unnecessary.
Funny that. I can't see that as being a requirement. Glad you agree with me that the UK government is taking an informed and scientific approach.
Re: Won't matter to politicians in the UK (Score:2)
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The science says to keep wearing masks until a pandemic is over.
You are confusing policy with science. Science predicts outcomes and describes consequences it never prescribes a course of action.
The policy maker (a political function) prescribes a course of action hopefully after carefully weighing evidence from scientific inputs against all other competing considerations.
Deaths are down in the noise, correct. Now tell us all why you propose killing people unnecessarily while a pandemic is still very much ongoing?
Policy in the US for example says vaccinated people can safely not wear masks indoors. UK is ahead of the US on a percentage vaccinated basis.
It is possible for two people to look at the same science
Re:Won't matter to politicians in the UK (Score:5, Insightful)
The pandemic is over
Nope. It hasn't been declared over the UK. Not by scientists, not by the government, not by international organisations.
Honestly after that I'm not even going to bother reading the rest of your post. I can just guess it's similarly completely uninformed bullshit. But hey, this is you we're talking about so that was kind of a given.
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It's really not a lot to ask to wear a mask to save your fellow human beings' lives
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Does Africa or India count as a "tiny minority" because this pandemic is far from over.
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Whats that got to do with the UK?
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A disease that affects Britain's trading partners, such as India and several African countries, thereby affects Britain.
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Even as people in wealthy countries go back to normal, we all still have an interest in wiping out this disease everywhere else.
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No, it's not my brother's choice to not get vaccinated while he's getting chemotherapy; it's his doctor's instructions. But you've suffered so much from wearing a mask, that you're fine with increasing his risk of getting CoViD-19 just so you can go maskless in public places.
We have not yet hit herd immunity. If everyone would get vaccinated and those yet un-vaccinated continued to wear
Until COVID+flu below 7 per 100K per week (Score:2)
How long should a requirement that unvaccinated individuals over age 7 wear a face covering in public indoor spaces last? I'm guessing it may continue until a state or province has reached an incidence (new case rate per capita) low enough to "contain" the disease. Websites such as Covid Act Now define "containment" as fewer than seven new cases per 100,000 people per week (one per 100K per day over a 7-day moving average). This means my own home county, with 5.3 cases per 100K per day, is about two and a h
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So the incidence reduction of flu was because of 'masking' eh? Nothing to do with the fact that kids weren't in school? Nothing to do with the fact that many people are working from home (or not working at all)? Nothing to do with the fact that many people have just been avoiding other people altogether? Nothing to do with the fact that there were no sporting events, concerts, live theater, movies, etc? Nope, none of that. It is all because of old tshirts being work over the nose.
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But when the kids go back to school and the movie theatres and sporting events open anew, masks will still be the simplest most non-intrusive layer to leave in place till last.
I'm hoping that may be a lasting legacy going forward, that it is more socially acceptable now for people to wear masks either when they don't feel well, or simply for their own protection. The change
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Even though all vulnerable people who wanted to be vaccinated have been
The government has to [act as if it] care[s] about all people, even the stupid ones, because people blame them for each unnecessary death whether it's the dead's own fault or not.
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Live virus vaccines arent really as common as they used to be. Theres still a few used in infant vaccination (and are proven quite safe), but in general virologists would prefer not to use live virus vaccines where possible due to them being unsuitable for immunocompromised folks.(No you wont get sick with the disease its vaccinating against and then infecting half the neighborhood, however you might have a rough time with the weakend variant, if your immune system is faulty, although you wont pass it on).
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They're more common than you think [hhs.gov]
He also included inactivated virus vaccines, because they become live virus vaccines when inactivated improperly [nih.gov].
That's one of the reasons the mRNA vaccine technologies being rolled out are so intriguing. No (rare) inactivation issues or concerns with live virus vectors [sciencemag.org].
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And towards which part of the summary is your critics aimed?
They do not mention at all "how vaccines work"
Or do you mean this:
In general, vaccines work by showing people's immune systems something that looks like the virus but really isn't.
That is actually exactly how a vaccine works ...
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Go get psychiatric help you raving lunatic.
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The common cold is a rhinovirus, not a coronavirus.
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OK, I looked it up. Wikipedia says about 15%.
Re:What magic is this? (Score:5, Informative)
Fair enough. I oversimplified rather than take the time to debunk the same bulls**t for the hundredth time. In the context of this thread, it seemed pretty clear that the person I was replying to was implying that COVID-19 is the common cold, which is approximately as far from the truth as you can get, because the vast majority of colds are not coronavirus, and COVID-19 is not one of the seven known coronavirus strains that cause a mild cold.
There are seven strains of coronavirus that can cause a cold in humans, and as I understand it, once you get a given strain, you're unlikely to get that same strain again. By contrast, RSV immunity wanes in adulthood, so it becomes a larger percentage of the total as you get older. Parainfluenza doesn't produce any lasting immunity (not sure why). And rhinovirus exists in such a large number of strains (triple digits at this point) that being immune to all of them is unlikely. (And also, it has a high mutation rate.) So by the time you reach old age, colds are almost certainly rhinoviruses or RSV or parainfluenza, not a CoV variant.
Better? :-)
Re: (Score:2)