Fauci 'Cautiously Optimistic' Vaccine Could Be Available by End of 2020 or Early 2021 (bostonglobe.com) 165
Dr. Anthony Fauci, the government's top infectious disease expert, told a House committee on Tuesday he believes "it will be when and not if" there will be a COVID-19 vaccine and that he remains "cautiously optimistic" that some will be ready at the end of the year. From a report: Fauci has returned to Capitol Hill at a fraught moment in the nation's pandemic response, with coronavirus cases rising in about half the states and political polarization competing for attention with public health recommendations. Fauci testified in his opening statement that a vaccine candidate for the coronavirus will enter Phase 3 of study in July. "This is one that has already shown in preliminary studies some very favorable response in the animal models that we've developed," Fauci said. Earlier this month, Cambridge-based Moderna announced the experimental COVID-19 vaccine it is developing with the US National Institutes of Health was on track to be tested in 30,000 volunteers -- some given the real shot and some a dummy shot.
Fauci was testifying along with the heads of the Centers for Disease Control and Prevention, the Food and Drug Administration, and a top official at the Department of Health and Human Services. Since Fauci's last appearance at a high-profile hearing more than a month ago, the US has been emerging from weeks of stay-at-home orders and business shutdowns. But it's being done in an uneven way, with some states far less cautious than others. A trio of states with Republican governors who are bullish on reopening -- Arizona, Florida and Texas -- are among those seeing worrisome increases in cases. Last week, Vice President Mike Pence published an opinion article in The Wall Street Journal saying the administration's efforts have strengthened the nation's ability to counter the virus and should be "a cause for celebration." Dr. Fauci also told lawmakers Tuesday that the US will be increasing coronavirus testing, saying, "we're going to be doing more testing, not less," in response to President Donald Trump's recent claim that he asked to slow down testing during the pandemic.
Fauci was testifying along with the heads of the Centers for Disease Control and Prevention, the Food and Drug Administration, and a top official at the Department of Health and Human Services. Since Fauci's last appearance at a high-profile hearing more than a month ago, the US has been emerging from weeks of stay-at-home orders and business shutdowns. But it's being done in an uneven way, with some states far less cautious than others. A trio of states with Republican governors who are bullish on reopening -- Arizona, Florida and Texas -- are among those seeing worrisome increases in cases. Last week, Vice President Mike Pence published an opinion article in The Wall Street Journal saying the administration's efforts have strengthened the nation's ability to counter the virus and should be "a cause for celebration." Dr. Fauci also told lawmakers Tuesday that the US will be increasing coronavirus testing, saying, "we're going to be doing more testing, not less," in response to President Donald Trump's recent claim that he asked to slow down testing during the pandemic.
A *Working* Vaccine? (Score:3, Insightful)
Let's not get ahead of ourselves.
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The challenge of doing more good than harm is so high because you want to vaccinate billions of people, the majority of which would not even suffer if they attact Covid. If you would target the high risk population the calculus would already change.
A while back I read about a chines candidate for a vaccine. Many of the testpersons became ill, fever, all kinds of symptoms. Nobody got seriously ill and nobody died but scale this up and one can imagine some people dying.
The effectiveness of the vaccine candid
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Not sure what point you are trying to make except that you don't like them. I know Gates expects to make a huge amount of money on vaccines but for the moment I still go on the assumption that he wants to make that money by making vaccines that do what they say they do.
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I have heard about the polio vaccine, that they used an approach which led to a higher incidence of actual polio with the accompanying paralyisis. I don't know yet what to think of it. In any case I don't see Gates as a do gooder, he's a capitalist who believes he should try to make money, but I still consider it likely that he wants to make money by delivering value. What the end result will be is another story.
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What you should think about it is that that was a bullshit story concocted by anti-vaxers, and recognize that the Gates foundation was not kicked out of India.
https://www.politifact.com/fac... [politifact.com]
https://www.snopes.com/fact-ch... [snopes.com]
In reality, India has not seen a single case of Polio since 2011.
There is an oral polio vaccine that CAN cause polio. It is extremely rare, but yes it can happen. It is not experimental. It's been used for decades.
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Thanks internet person. I heard a lot about 'idiotic antivaxxers' without knowing what it was about, and I intend to dig into this a bit. They have a remarkable amount of claims. What I should do about this is take my time to understand the situation rather than rely on the debunking of a single claim. A quick search (https://extranet.who.int/polis/public/CaseCount.aspx) shows that the AFP rate has gone up a lot since 2000 so I would want to understand the reliability of polio AFP vs non-polio AFP vs suspec
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Right. One that does more good than harm. Rushing this out doesn't inspire confidence for me but likely does for the "economy".
Before you shit all over concern for the economy, and I will grant certain factions want it better, but also certain factions want it worse (I hear AOC has a tweet for you) and also heavily rely on class warfare, insensate rhetoric: "Economy worth one death? Ptui!" keep in mind our slowed economy may be putting us months behind where our R&D and general economic progress might might have placed us, and people will die because treatments for all ailments are somewhat delayed.
How many? Remember the shif
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IMO, the biggest risk with a COVID-19 vaccine is that it could cause CRS (Cytokine Release Syndrome) in the same patients who would have died from the actual disease. After all, what kills you isn't the virus; it's your immune system's overreaction to it. I'd feel a LOT more comfortable if the first vaccine out of the gate were the one delivered by microneedles (PittCoVacc), which seems more likely to ensure that any reaction remains confined to your skin, rather than possibly getting into your bloodstre
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After all, what kills you isn't the virus; it's your immune system's overreaction to it.
You sure it's never the lung damage?
Well one of the things that it does (Score:3)
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After all, what kills you isn't the virus; it's your immune system's overreaction to it.
You sure it's never the lung damage?
I'm pretty sure that it's the inflammation that causes the worst of the lung damage. I mean, there's some direct damage from cells getting infected, too, but my gut says that it is a rare cause of death, percentage-wise.
Re: A *Working* Vaccine? (Score:2)
I don't suppose your gut has a medical degree.
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No, but I've read and/or skimmed a lot of research papers on the subject, so at least it is a fairly well informed gut. :-)
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I'm not sure it would confine it, per se, but my thinking is that the more direct the interaction with your bloodstream, the more likely that the epithelial cells in your blood vessels are to react like they do to the virus. An injection results in bleeding, so it seems likely to me that more of the vaccine would actually get into your bloodstream than with a microneedle array, which is superficial.
Riddle me this... (Score:2)
If it takes 6 months to scale up and produce hundreds of millions of doses.... then where is the PROVEN vaccine.... because it is almost July
Nothing that this administration says adds up
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That's why we're probably not going to wait before a vaccine is proven before scaling up manufacturing. Enough is at stake that its worth wasting the money on mass production even for candidates that don't pan out.
I recall the Bill Gates going on record saying that his foundation is funding factories for at least 7 of the vaccine candidates for exactly this reason.
Couple things. $250,000 "wasted" (Score:5, Informative)
First, Fauci didn't say everyone would be immunized by the end of the year. That's something you completely made up in order to poke at it. That's called a straw man and here on Slashdot we recognize that for what it is. Try Facebook for that crap, where there are more people who don't engage their brains.
Second, you might remember that while universities ans government labs in two dozen countries were testing Remdesivir and hydroxychloroquine because they seemed to be our best shot, Fauci said if either drug made it as far as phase 3 testing, we should go ahead and start making "a couple million doses" of hcq so that if the stage 3 trials confirm they should be used, we'd have the medication mostly ready. Rather than sitting in our hands doing nothing and waiting, as you seem to suggest is the only course one can take.
You might recall you had a good laugh last week because now we have three million doses of hydroxychloroquine we don't need, which cost $250,000 to make. (Hydroxychloroquine is really cheap to make).
Phase 3 of the vaccine should start in about a week or two, so he might well recommend we start production at around the same time, so it'll be ready if and when we know it should be widely administered. If the phase 3 goes poorly, then we spent a few million dollars producing a vaccine that we don't end up using. Oh fucking well. They are already spending the $500 million to reset and develop the vaccine. Another $20 million to produce a bunch of it really isn't a big deal.
Re:Couple things. $250,000 "wasted" (Score:5, Funny)
"That's called a straw man and here on Slashdot we recognize that for what it is"
Eh, I've been on Slashdot for 20 years and we totally wallow in strawmen here.
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"That's called a straw man and here on Slashdot we recognize that for what it is"
Eh, I've been on Slashdot for 20 years and we totally wallow in strawmen here.
Actually, scarecrows are in use all around the world and have been for more than a millennia. I don't know why you'd fallaciously suggest that we have any sort of basis for an exclusive claim to them on Slashdot.
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Not Fauci, his boss... you know Mr I say a lot of shit but never really deliver...
Trump sets goal of hundreds of millions of coronavirus vaccine doses by January, but scientists doubt it [washingtonpost.com]
So, maybe Trump totally made it up, but I am just pointing to the impossibility of delivering on his promises regardless of what you apologist shills want to spew
I'll not wait on your apology
So this is called a quotation mark (Score:2)
> Not Fauci, his boss ...
> Trump sets goal of hundreds of millions of coronavirus vaccine doses by January, but scientists doubt it
So this little mark thing " is called a quotation mark.
When someone says Fauci once recommended making "a few million doses" of hydroxychloroquine (which costs about $250,000, the part within the quotation marks is his exact words.
Which has approximately nothing whatsoever to do with a few months later somebody said he hopes something about a completely different category
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There are none so blind as those who will not see
I will designate you as blind, since you refuse to see the the failing of this administration
The President (head of the administration) said that there will be hundreds of millions of doses of VACCINE ready by next January, Fauci, who is able to recognize the impossibility of that statement then slowly walks it back to something that is remotely feasible
And YOU just want us to forget what your Dear Leader said in the first place
There is a little place call No
Did you forget what you just said? (Score:2)
Garyisatdsguy said:
> Trump sets goal of hundreds of millions of coronavirus vaccine doses by January
In fact his actual words were: ... development of effective treatments and vaccines as quickly as possible. Want to see if we can do that very quickly. Weâ(TM)re looking to â" when I say "quickly," weâ(TM)re looking to get it by the end of the year, if we can. Maybe
--
--
I guess that qualifies as "sets a goal", though personal development people will tell you goals don't come with "if we ca
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lol, what the fuck are you on buddy? Get some sleep, then come back read the article and see what a fool you have been
Just to summarize, my original post:
>Riddle me this... (Score:2)
>by garyisabusyguy ( 732330 ) on Tuesday June 23, 2020 @11:41AM (#60217974)
>If it takes 6 months to scale up and produce hundreds of millions of doses.... then where is the PROVEN vaccine.... because it is almost July
>
>Nothing that this administration says adds up
Just in case you have a comprehension problem...
1.
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The administration has its issues with communication however Dr. Fauci did not guarantee that hundreds of millions of people will be vaccinated by the end of 2020. He said he was "cautiously optimistic" that there would be a vaccine by the end of 2020. You didn’t have to read the article to spot this difference. Just read the summary. If all goes well, he hopes they will be making vaccines by the end of 2020.
This is the same difference between "my package is expected to be delivered Thursday" and "my
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Not Fauci, his boss. See my reply to RayMorris above
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Yes they have to scale up long before they know it will work and not kill more than it saves. But that is accounted for and government should eat the cost if it fails. Why?
Government (just the US) is on target to borrow an extra $6 trillion this year alone. On top of the normal one trillion.
Eating a few hundred billion is nothing. Moonshot prices are worth it to get the economy open one month early.
"Available" doesn't mean you can get it (Score:5, Informative)
On the plus side the healthcare workers will test it for you.
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I don't want to be first in line anyways!
I'm not anti-vax, but the rush to get these vaccines out scares me.
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Warning! The initial vaccines have a common (5-10% chance) side-effect of causing you to grow a tail. Tell everyone you know!
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"Vaccine" and "Available" are yet to be Defined (Score:4, Insightful)
All medicines have fail rates. I'm sure many vaccines are being tested right now, but how effective the vaccine is will determine whether it's accepted as "the" vaccine. My guess is that, given its spread, this will need to be like the flu vaccine with multiple flavors and annually updated.
Additionally, "available" is a funny word. You can have a single vial of "the" vaccine, but then need to begin mass production. And for whom? The US? The World? Those who can afford it? Then there's bureaucracy of distribution and injection.
So, I'll be cautiously optimistic, too. But I'm thinking that 1 or 2 potential candidates for "the" vaccine will be available by December and they'll be seeking contracts so they can begin mass production.
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Additionally, "available" is a funny word. You can have a single vial of "the" vaccine, but then need to begin mass production.
The vaccines being tested are already being produced "speculatively" so that if the vaccine is found useful, we will have a ready supply to distribute.
And for whom? The US? The World? Those who can afford it?
The Trump administration has committed to ensuring every American can get the vaccine, whatever it is, at no cost. Other countries will have to figure out what they will do.
Then there's bureaucracy of distribution and injection.
Which we do year after year for countless medicines, and the US Military has stepped forward to lend it's logistical expertise to distributing the vaccine wherever it is needed.
It kind s
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The Trump administration has committed to ensuring every American can get the vaccine, whatever it is, at no cost. Other countries will have to figure out what they will do.
Is this the same administration who claimed on March 6th that, "Anybody who wants a test gets a test," but by June 1st that was still nowhere close to true [cnet.com]? Why should we believe their statements about availability of a vaccine?
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"It kind seems like you just decided it was a big problem (which it is) and assumed everyone involved was somehow less aware of the issues than you are, so it was important for you to point out the issues no one else thought of."
Nope, I'm not talking about peoples' capabilities to plan. I'm talking about them mincing words so that grander expectations can be made for political benefits instead of managing likelihoods that the vaccine will be accessible to Bill the plumber in December 2020.
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But I'm thinking that 1 or 2 potential candidates for "the" vaccine will be available by December and they'll be seeking contracts so they can begin mass production.
Production is being done now, during the clinical trials - there will be millions of doses available by the time the clinical trials are completed. Haven't you heard this in the media? It was widely discussed after Dr. Fauci described the massively parallel effort the administration is using to have vaccines available as soon as possible.
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My guess is that, given its spread, this will need to be like the flu vaccine with multiple flavors and annually updated.
Not sure if you don't understand the flu vaccine or COVID-19. The reason the flu vaccine comes in multiple flavours that are *bi-annually* updated is due to the different strains of the flu we treat against and absolutely nothing to do with the spread of any given flu.
COVID-19 doesn't have multiple strains of viruses to chase around the world with vaccines. It has one virus, SARS-CoV-2. We need one flavour to kill that specific corona virus. Just like you only need one specific vaccine to to prevent someone
"Cautiously optimistic" (Score:2)
The same people (Score:2)
The same people who said the virus is a hoax and then refused to social distance or stay home and are now refusing to wear masks will also refuse to be vaccinated.
Election Year Fun (Score:2)
Then comes the "papers please" phase where people will be denied service or admittance if they cannot show proof of COVID vaccination.
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Re: Translation ... (Score:2)
How does that theory apply to places outside of our boarders?
At least the conspiracy theories about China taking advantage of the pandemic have a sort of logic to them, even if the evidence is lack.
An anti-Trump conspiracy like this has no logic to it. How do you get your brain here? Taking the wrong dose and mixing red pills and blue pills with OxyContin? I assure you, the left thinks they will win 2020 just like they assume they'd win 2016. They aren't capable of orchestrating mandatory mask wearing as a
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An anti-Trump conspiracy like this has no logic to it.
"Tom Nichols remarking about Trump's trade policies, saying "I'm not wishing for a recession, but if the farmers want to keep touching the hot stove."
“Well, you should be," Maher interjected. "Because that will definitely get him unelected."
"But Bill, you don’t really want a recession," shot back Anthony Scaramucci, Trump's former White House communications director and a now occasional critic of the administration.
“I really do. We have survived many recessions. We can’t surviv
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LOL. Bill Maher is a a well known contrarian who has little practical influence in the real world beyond his entertainment value. He's a shock-jock for the intellectual crowd, his peers are people like Joe Rogan and not people like Bill O'Reilly
I think you'll have to dig up something substantial to indicate there is a conspiracy to get Trump out. More so than Maher's hyperbolic statements equivalent to standing back and watching it all burn. Even his guest, leftist Tom Nichols, had trouble following Maher's
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Even his guest, leftist Tom Nichols, had trouble following Maher's logic
That is utterly false, the logic was well understood. He merely expressed disagreement. Now consider various other election cycles where people have been accused of talking down the economy as part of a political campaign. This particular downturn is especially attractive since we have an otherwise healthy economy dealing with a temporary disaster. Either the virus will burn out, an effective course of treatment found, or herd immunity will develop. Extending the crisis, or at least its negative economic im
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Extending the crisis, or at least its negative economic impact, to November is a doable thing.
And you believe this is doable on a worldwide scale? interesting.
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Extending the crisis, or at least its negative economic impact, to November is a doable thing.
And you believe this is doable on a worldwide scale? interesting.
That's a fairly obvious red herring you offer. When to re-open the US is not an international issue. It is however an issue for US politicians and the US press, and damage to Trump can make "later" look like a more attractive option to some of the preceding. Nothing mysterious about it being part of the calculation. "Never Let A Good Crisis Go to Waste" - Rahm Emanuel
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Again, no one is claiming that pandemic is some sort of conspiracy. Merel
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rather evidence of a return to the strong economy
Honestly the bond market was shit before this. That is a key indicator of an economy with problems. We kept pumping this so-called great economy with lower interest rates, the opposite of what a sane person would do with a good economy. Our economy has all been a big show, ready to collapse at the first major event. Our fake economy is not even Trump's fault, but he and his base are totally blind to what is going on.
He was elected due to economic and job fears
There was concerned that Hillary committed some crimes. Fabricated by Roger Stone. "lock her
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I agree in principal that an economy with massive government stimulus (pre-CV19) is in an artificial state. Its as true under Trump as it was under Obama and Bush. However to be practical its not a distinction that voters typically make.
I'm not convinced of a pending collapse. The current economic slowdown is largely an effect of things in our control, governors' directives, not great macroeconomic forces beyond our control. If we reop
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We do not need to sabotage the country, Trump is doing that all by himself via mismanagement.
Oh you silly little ... (Score:2)
Oh you silly little "useful idiot" of the far left, I have not and will not be voting for Trump. You don't need to be a Trump supporter to notice the extremely politicized positions on the virus and our actions to minimize its the effect.
Oh you silly little pompous ignorer of science, severe lockdowns don't prevent this sort of disease in modern society. Did you fail Bending the Curve 101? Roughly the same number of
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TL;DR so I'll just go with my lazy response of "Fuck you." You are way too fond of the taste of your own asshole.
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You know this is just "I know you are but what am I?" while trying too hard to sound smart, right? Fucking grade school level come back, nice.
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You know this is just "I know you are but what am I?" while trying too hard to sound smart, right? Fucking grade school level come back, nice.
LOL - accusations of immaturity from the kiddie with a new word. OMG, thank you, I couldn't make this stuff up. You literally turn jokes into reality.
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Nobody here likes you
Ah, thank you for explaining the origins of your insecurity and overcompensation.
Even with all the downvotes I get from triggered conservatards, I still have perfect karma.
You are a little confused as to who got triggered today. Also thanks for adding to your insecurity displays by bringing up the meaningly virtue signaling karma. The most amusing thing about your attempt to elevate yourself is that I too have excellent karma despite the occasional downvote. Excellent karma is a meaningless and easy achievement.
But thanks again, you are truly a gift that just keeps giving.
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Wait, are you so dumb that you think you came out ahead here? With that dime store psychology? Oh dear. The Dunning-Kruger effect is really something, isn't it?
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The Dunning-Kruger effect is really something, isn't it?
LOL -- That comment is unlikely to be interpreted as you think it is. OMG you are such a gift.
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Do you think that continually asserting you feel amused would lead me to believe you are, in fact amused? That's grade school mean girl style tactics, and won't work on anyone past high school. Seriously, why do you even keep responding, with essentially the same statement, over and over again?
It's because I've got you hooked like a fish. Triggered and shook, and you can't let it go, can you? You keep trying to "win" but it's just you and me here in this thread now, no one else is reading this.
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Do you think that continually asserting you feel amused would lead me to believe you are, in fact amused?
Please do not and continue.
That's grade school mean girl style tactics, and won't work on anyone past high school
Thank you for the additional insight into your thought processes and level of sophistication.
It's because I've got you hooked like a fish. Triggered and shook, and you can't let it go, can you?
OMG this is too good. I posted a joke, the first post of this thread. And in the second post in this thread, the **first response**, you had a woosh moment and got triggered, responded with angry silly profanity, and you talk now of triggering and being hooked. This is f'n amazing. Please re-read those first two post and reflect on who was triggered and hooked. LOL.
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Ah yes, Schrodinger's Joke, the favorite tactic of authoritarians and asshole everywhere. Audience offended? It was just a joke bro! Audience buys it? Hey good buddy, join the club!
Your comment history indicates what your political leanings are. You obviously like to think of yourself as "rational" but your biases are transparent. You reek of smug pseudo-intellectualism. Keep it up though, your posts are as entertaining for me as you claim mine are for you.
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BTW -- its especially amusing to watch you attempt the "you are, well so am I" bit. Its almost as if you forgot you labeled such a reaction childish earlier. Yet another self contradiction as you struggle.
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Don't worry, the factors you listed will probably cause the virus to naturally immunize most of the population by the time an actual vaccine is available.
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Let me guess, you also never use the seat belt because you had no car accidents so far.
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You don't take the vaccine so _you_ don't get sick. We all take the vaccine so we don't _all_ get sick.
If vaccines don't help keep me from getting sick/infected, then how does the vaccine prevent me from infecting other people?
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I guarantee you that the government will cover vaccinations for everyone regardless of insurance/money/etc.. There's a reason that there are widespread free vaccination programs. The idiot anti-vaxxers are a problem; personally I think they should be vaccinated by force.
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Between the folks that don't have insurance (8%), don't have a doctor (15%), and don't have the money, you're already talking about 15-20% of the population. Throw in the anti-vaxxers (5%) and people that aren't going to want to be part of the human trial (15%) and you're getting close to 40% of the population that won't be standing in lines to get this vaccine and that is before you get to the political stuff.
What BS - Everyone that thought the virus was so bad that they chose to stay home, leave their jobs, and wear masks and social distance these last three months will likely get vaccinated. Anyone that puts their opinion of Trump before their health is making a porr choice. As noted above, you don'
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Between the folks that don't have insurance (8%), don't have a doctor (15%), and don't have the money, you're already talking about 15-20% of the population.
You can get flu vaccines at local pharmacies, and state/federal governments are going to cover the cost of the vaccine. You don't need insurance or a doctor for a COVID vaccination.
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The theory is America experiences tectonic shifts in society roughly every 50 years and this is the end of the old cycle. SARS-CoV-2 is just an extremely odd additional catalyst.
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Its either that, or we're getting better at treating it. Probably a combination of both.
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The virus doesn't care what Infowars says, guys.
Well, it's a good thing he didn't use Infowars as a source to make his point that deaths per day are dropping.
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The graphs only went down because of the stay at home orders. The graphs are now going back up because the man-babies both outlasted the orders and decided that literally any social distancing behavior only functioned as liberal virtue signalling.
The graphs going down were a completely expected result of the stay at home orders, and "ignored" because the man-baby be
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Bully for Virginia. Virginia is not the United States [rt.live]. All those states in red, where Rsubt is >1.0, are seeing increasing caseloads. So let's argue about, say, Hawaii.
They're not going down. I, for one, do not live in Virginia, and have no reason to limit my worldview to the confines of Virginia.
Re:Might not be needed... (Score:4)
It may be losing its virulence [telegraph.co.uk] and the number of deaths has been consistently plummeting [worldometers.info] since the peak of April 21.
The number of deaths haven't been "consistently plummeting" https://www.worldometers.info/... [worldometers.info]
And it's "losing its virulence" is being promoted by one crackpot doctor who does not seem to understand genetics.
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Re:Might not be needed... (Score:4, Informative)
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https://outkick.com/media-igno... [outkick.com]
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The experts warned this was going to be a pandemic. Lo and behold, it be that. Then they warned that opening up the way the red states were would cause increasing outbreaks there, and it is so.
Latest "anti-Trump" moves, the EU is considering barring travelers from the U.S. because the U.S. cannot get their shit together. Read between the lines and they mean the alleged administration cannot get their shit together and have given up doing anything about the pandemic in the U.S.
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You probably need to be institutionalized, and I'm not exaggerating this.
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