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Research Offers Promise of Devices That Can Detect Disease With a Drop of Blood 27

Posted by samzenpus
from the just-a-drop dept.
An anonymous reader writes "An NJIT research professor known for his cutting-edge work with carbon nanotubes is overseeing the manufacture of a prototype lab-on-a-chip that would someday enable a physician to detect disease or virus from just one drop of liquid, including blood. 'Scalable nano-bioprobes with sub-cellular resolution for cell detection,' (Elsevier, Vol. 45), which will publish on July 15, 2013 but is available now online, describes how NJIT research professors Reginald Farrow and Alokik Kanwal, his former postdoctoral fellow, and their team have created a carbon nanotube-based device to noninvasively and quickly detect mobile single cells with the potential to maintain a high degree of spatial resolution."
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Research Offers Promise of Devices That Can Detect Disease With a Drop of Blood

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  • by wcrowe (94389)

    (sigh) Now if they could only detect blood glucose level without a drop of blood.

  • Blood?! (Score:4, Funny)

    by dohzer (867770) on Monday June 24, 2013 @04:39PM (#44096453) Homepage

    Of all the fluids they could use, blood is one of them! Who'd have thunk it?!
    I've heard they can also detect gender with a single drop of semen.

  • by Anonymous Coward

    This tool would be indispensable when deciding if it's a good idea to bring "Candy the Stripper" home after a long night of drinking. When will the personal version be available?

  • by Anonymous Coward

    that brings out the very worst gee whiz flying nuclear powered personal cars batman style here on slashdot ?

    how big is a drop ?

    About 50 - 100 uL (microliter, one cubic mm)

    What sensitivity do you need to detect viruses and bacteria ?

    you need to be able to detect things in the organism per mL range
    A mL is 1,000 uL
    Therefore, by definition, a drop of blood is prettty much useless for detecting viruses and bacteria in a serious way (oh, you died of S aureus sepsis cause we only sampled a small drop of blood and

  • by ichthus (72442) on Monday June 24, 2013 @05:14PM (#44096645) Homepage
    You mean, like these guys [biofiredx.com]?
  • Isn't this old news? I seem to remember reading stories about the potential of this over 5 years ago - but they were talking about doing a couple hundred tests on a drop of blood.

    Well, this is perhaps a bit more specific, which would be a good thing, but it seems to be a major step back.

    Though if they can get it good enough to tell bacterial strains with a single drop without having to do DNA analysis, it might help with treating such diseases with phages(viruses that infect/kill bacteria), allowing us to

  • by Anonymous Coward on Monday June 24, 2013 @06:03PM (#44096865)

    "Elsevier" is a publisher, not a publication. The actual journal reference is Biosensors and Bioelectronics Volume 45, 15 July 2013, Pages 267–273

  • by Anonymous Coward

    http://www.forbes.com/sites/bruceupbin/2012/06/18/wait-did-this-15-year-old-from-maryland-just-change-cancer-treatment/

    Andraka’s diagnostic breakthrough is a humble piece of filter paper, except that it is dipped in a solution of carbon nanotubes, which are hollow cylinders with walls the thickness of a single atom, coated with a specific antibody designed to bind with the virus or protein you’re looking for. Andraka’s key insight is that there are noticeable changes in the electrical cond

  • University Herlald article is not worth reading. No word on how it works.
  • by locopuyo (1433631) on Monday June 24, 2013 @11:16PM (#44098141) Homepage
    This isn't going to go anywhere. Vampires are going to buy it and bury it so you have to give pints so they can send it to the "lab" for testing.
  • Diagnostics is the hardest part!

  • by Anonymous Coward

    are a standard theme among lab-on-chip researchers. It should be keot in mind that micro total analysis systems (micro-tas) are thought about since the first minituarized electrophoresis systems were shown. But as a matter of fact, there are no point of care diagnostic tools alvailable to date that do not rely on the dip stick (or generally lateral flow) design. Why is that ?

    Well the reasons are:
    * Blood is a hard matrix (even urin is not fun to deal with apart from the smell)
    * Valving/dosing systems on a c

  • Biosensors and Bioelectronics (where this was published) publishes dozens of papers a month like this. There are many equivalent journals published by Wiley, ACS and I'm sure many smaller University presses. We're at a point where publishing a paper is not a useful metric to demonstrate an advancement. There are too many recycled ideas, impractical demonstrations and outright (though peer-reviewed) lies.

    Does he have a clinical partner willing to test this in a working hospital? Does he have financial ba

The reason that every major university maintains a department of mathematics is that it's cheaper than institutionalizing all those people.

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