Lasrick writes: Martin Furmanski, a medical doctor and medical historian, writes of the laboratory escapes of high-consequence pathogens that have occurred in recent decades (including several instances of smallpox!). The article explores "gain of function" experiments-- experiments in which researchers manipulate dangerous pathogens to increase communicability among humans, and whether the benefit we see from those experiments outweighs the incredible risk. 'Many other laboratory escapes of high-consequence pathogens have occurred, resulting in transmission beyond laboratory personnel. Ironically, these laboratories were working with pathogens to prevent the very outbreaks they ultimately caused. For that reason, the tragic consequences have been called “self-fulfilling prophecies."' Interesting topic that doesn't get much attention in the main-stream press, unless it's part of a Hollywood movie.