Scottingham writes: PhsyOrg describes this discovery better than I could: A single "giant", non-spiking, GABAergic interneuron forms an all-to-all negative feedback loop with a population of about 50,000 Kenyon cells, principal neurons of the mushroom bodies, a structure involved in olfactory memory in the insect brain. This normalizing feedback loop serves to ensure relatively constant sparseness of mushroom body output across varying input strengths. Sparseness is an important feature of sensory representations in areas involved in memory formation.
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