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Medicine United States

Woman Sheds Coronavirus For 70 Days Without Symptoms (livescience.com) 126

An anonymous reader quotes a report from LiveScience: A woman with COVID-19 in Washington state shed infectious virus particles for 70 days, meaning she was contagious during that entire time, despite never showing symptoms of the disease, according to a new report. The 71-year-old woman had a type of leukemia, or cancer of the white blood cells, and so her immune system was weakened and less able to clear her body of the new coronavirus, known as SARS-CoV-2. Although researchers have suspected that people with weakened immune systems may shed the virus for longer than typical, there was little evidence of this happening, until now. The findings contradict guidelines from the Centers for Disease Control and Prevention (CDC), which say that immunocompromised people with COVID-19 are likely not infectious after 20 days. The new findings suggest "long-term shedding of infectious virus may be a concern in certain immunocompromised patients," the authors wrote in their paper, published in the journal Cell. "The virus was detected in her upper respiratory tract for 105 days; and infectious virus particles -- meaning they were capable of spreading the disease -- were detected for at least 70 days," the report says. "Typically, people with COVID-19 are contagious for about eight days after infection, according to the report. Previously, the longest duration of infectious virus shedding in a COVID-19 patient was reported to be 20 days."
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Woman Sheds Coronavirus For 70 Days Without Symptoms

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  • I wonder how many others have this unique ability to give the gift that keeps on giving?
  • no contradiction (Score:5, Insightful)

    by jbmartin6 ( 1232050 ) on Friday November 06, 2020 @09:19AM (#60691078)

    The findings contradict guidelines from the Centers for Disease Control and Prevention (CDC), which say that immunocompromised people with COVID-19 are likely not infectious after 20 days.

    There is no contradiction. The CDC guideline uses the term 'likely' to indicate a certain level of uncertainty. There is a large amount of variation in reactions to disease, the woman in the article is likely an outlier. (see? not certain, just likely)

    • by Entrope ( 68843 ) on Friday November 06, 2020 @09:26AM (#60691106) Homepage

      A one-in-50,000,000 occurrence is pretty much the definition of outlier. It's like the person who was definitively confirmed to have been re-infected (by a different strain of SARS-CoV-2): Not surprising that it happened to someone, somewhere, but at least a little reassuring that it isn't more common.

    • by hey! ( 33014 )

      In an pandemic with fifty million documented cases the tails of the probability distribution are extremely long.

      Events inevitably occur that are so rare that they have no practical significance to the public. They neither augur the furture course of the pandemic nor change anything the public ought to be doing. But fear draws eyeballs and eyeballs are valuable, so you can be sure the public will hear all about these outlier events.

      Of course events like people getting reinfected with the virus or asymptomat

  • by kot-begemot-uk ( 6104030 ) on Friday November 06, 2020 @09:29AM (#60691118) Homepage
    Typhoid Mary Mk2. Bigger, Better and Uncut.
  • Is that consistent? (Score:4, Interesting)

    by hcs_$reboot ( 1536101 ) on Friday November 06, 2020 @09:37AM (#60691136)
    Her immune system is weakened yet she has no symptoms!
    • by DarkOx ( 621550 ) on Friday November 06, 2020 @09:47AM (#60691166) Journal

      probably, yes!

      Most of the most easily observable symptoms to disease like covid-19 are in fact immune responses.

      The coughing, fever, congestion, lung tissue inflation etc, are all basically the bodies various attempts to fight the thing.

      Assuming a weakened immune system does not mount a strong a response, than what is left is things like damage to the oxygen exchange tissue in the lungs etc which may be subtle until its pretty severe, and things like fatigue which a cancer patient probably already suffers from and wont be able to separate from further fatigue possibly related to the covid. I am not a doctor but from what I know about all this stuff, it seems to pass he basic common sense smell test.

      • by dgatwood ( 11270 )

        Assuming a weakened immune system does not mount a strong a response, than what is left is things like damage to the oxygen exchange tissue in the lungs etc which may be subtle until its pretty severe... .

        ... and is also likely entirely caused by an overactive immune response. And even if it isn't, coronavirus can attack cells in any tissues, not just the lungs, so it is possible that her infection was introduced primarily through other exposed tissues (nose, throat, intestines), in which case it should affect the lungs no more than any other tissue.

    • Most of the worst symptoms are from an overreaction of the immune system. That's why kids are relatively unaffected in general. To someone who is immunocompromised, it's often a cold virus and little more. But "immunocompromised" is quite a blanket term, so it wouldn't affect all of them the same.

    • Her immune system is weakened yet she has no symptoms!

      I don't think you understand how the body works, at all.
      When you get a fever, is that because the pathogen increases your temperature? No, it isn't, it's the body's response to try and get rid of the pathogen.
      When you get a runny nose, is that because the pathogen is making your nasal secretary glands hyperactive? No, it isn't, it's your body trying to get rid of the pathogen and protect your exposed skin.
      When you get AIDS and *die*, is that because HIV is destroying your body with evil machinations? No, it

    • by Guppy ( 12314 )

      Her immune system is weakened yet she has no symptoms!

      I few years back encountered a kidney transplant on anti-rejection medications, who caught the flu. Mild persistent fever, but otherwise not really any symptoms, patient said he'd been walking around with a fever for weeks, but otherwise felt pretty normal. Anyway, the guy's influenza antigen testing was also positive for quite a few weeks after the start of his flu -- we didn't prove actual shedding of viable virus (using viral culture techniques), but I wouldn't be surprised if he'd been doing so the en

    • A great many symptoms for illness are a result of your immune system's actions in combating the pathogen, especially early symptoms before cumulative damage would take its toll on organ function.
  • They knew she has the virus yet they let her shed the virus for 70 days!
    • by dargaud ( 518470 )
      And how do you propose they get rid of her viruses ? There's no cure yet.
      • Well, at least they could have her not shed the virus?
        • Well, at least they could have her not shed the virus?

          I can't find the link now, but I read a story about how Trump tried to clean her out with bleach but the Biden-supporting doctors wouldn't let him. He did all he could, so it's clearly Biden's fault that she continued to be contagious. So yeah, you're right, they clearly wanted her to continue shedding.

        • Seriously? And how would "they" do that?

    • by PPH ( 736903 )

      She was living in a nursing home. The protocol is to isolate patients testing positive and feed them pancakes.

      Not because pancakes are any kind of therapy. But it's the only food they can slide under the door.

  • Mild Cold/flu symptoms continue on in immune compromised people for long periods as well. We just never looked at it with this much intensity before. What's more important is the concentrations she was shedding.

  • Comment removed (Score:5, Insightful)

    by account_deleted ( 4530225 ) on Friday November 06, 2020 @09:48AM (#60691170)
    Comment removed based on user account deletion
    • Re: (Score:2, Insightful)

      by flyingfsck ( 986395 )
      Well, your aunt does have a point about missing her medical appointments. In the UK, about 11% of people who died from Covid19 got it in hospital. So whenever there is a new disease, it is a good idea to stay away form the hospitals and doctors if you can, since that is where all the sick people go.
    • If you're in a general upper age risk factor, don't schedule routine tests and screenings during cold and flu season. And during a pandemic year, just avoid it entirely unless you have new concerning symptoms. That's about the end of it. Flu and other non-recent diseases are enough reason to not be in a hospital when you don't have to. Wearing a mask indoors won't help much if you're in a room with a constant high density of sick people and insufficient ventilation.

      That doesn't mean that paranoia is hea

    • As long as there are hospitals, e.g. in Texas, run and managed by Trump supporters, where the boss advices "greeting personal" and "ordinary daycare nurses" not to wear masks. Punished by firing if he sees them with a mask. As long as that bullcrap can happen in a hospital, I would not go there either for a routine check up. Actually I would not go there ever gain.

      Why do I know this random anecdotes? The daughter of one of my acquaintances works there. She is German. So if she gets fired she has to leave th

  • by LatencyKills ( 1213908 ) on Friday November 06, 2020 @10:25AM (#60691312)
    I'll have to wait until Trump tweets an opinion for me.
  • Do they mean "carried" as in "she was a carrier"?

    • by PPH ( 736903 )

      Carriers don't always shed. Although I don't know if anyone is certain about the Coronavirus life cycle, there are viruses that can go dormant in a persons body. And then revive from time to time, making them shedders. But they are always carriers.

  • A modern typhoid mary!

  • Lamb born with two head!

  • It was good enough for Typhoid Mary and so I guess also for Covid-Claire.

  • The findings contradict guidelines from the Centers for Disease Control and Prevention (CDC), which say that immunocompromised people with COVID-19 are likely not infectious after 20 days.

    The guidelines are statistical in nature. Enough people are not contagious after 20 days for it to be considered safe to assume they're not anymore. There's always outliers.

    It's a population level risk assessment, on the individual level there are no guarantees.

  • A virus is a protein "machine" that hijacks cells' protein-making engines to assemble more viruses. A successful virus wouldn't need to turn your lungs into mush, nor does it benefit triggering a huge immune response.

    Someone who is under a constant state of inflammation might go for weeks (months!) with a virus that neither increased to the point of overwhelming the body, nor to decrease to the point where the infection resolves. A state of equilibrium is possible under the right circumstances, but doesn't

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