B Vitamins Reduce Schizophrenia Symptoms, Study Finds (newsmax.com) 90
A new study published in the journal Psychological Medicine finds that high doses of B vitamins reduce the symptoms of schizophrenia. Researchers found that using B vitamins, including B6, inositol, and B12 as an adjunctive with antipsychotics significantly improved symptoms of the debilitating condition. Newsmax reports: For the new study, researchers identified 18 clinical trials with a combined total of 832 patients receiving antipsychotic treatment for schizophrenia. They found that B-vitamin interventions which used higher dosages or combined several vitamins were consistently effective for reducing psychiatric symptoms, whereas those which used lower doses were ineffective. The evidence also suggested that B-vitamin supplements were most beneficial when they were added to medicine regimens early after diagnosis.
Re:Ray Kurzweil (Score:5, Interesting)
Funny, the only schizophrenic I've ever known was also vegan.
I'm a vegetarian, and have strong sympathy for the motives behind being vegan. But take your B-12, my vegan friends. Unless you eat large amounts of soil, feces, or bacterial concentrates, or you've had a rumen implanted in your body, you need it. Higher plants don't make it. Every "vegetarian" mammal has to get it from somewhere, and those not lucky enough to have rumens (or other organs filling equivalent "cultivate lots of bacteria" roles) either get it through eating soil, feces, insects (accidentally or on purpose), or other such sources. Even our "strict" vegetarian gorilla relatives eat grubs. Heck, even though I consume dairy, I still take a B-12 supplement, just to ensure that I get enough.
Also, B-12 shortage doesn't hit you immediately. The body stores about 5 years of B-12. So it'll catch up with you sooner or later.
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Isn't a B-12 deficient diet an example of malnutrition?
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The fact that a particular tofu manufacturer may fortify their product with B12 is only because they know that a lot of their market is vegan. Not all vegans eat tofu, or will pay attention to whether their brand does or does not fortify. Not all eat cereal either (the main "multivitamin-fortified" food that people consume), and a serving of a typical fortified cereal only provides about a quarter of your RDA anyway. Lots of other foods are forti
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Those B-12 supplements usually have something like 36666% of the RDA per pill. So I just take them like once a week, and I figure I'm still getting plenty. I know I won't absorb all of the B12, but even if I absorb a couple percent, I'm good.
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Yeah, it's crazy how much they put in them. The human body requires utterly miniscule amounts of B12. But the difference between "miniscule" and "none" has a big impact :)
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Vegans do. Vegetarians can get it from milk and eggs.
And hey, that can be turned around if you want to play that game. Your typical American eats var too few vegetables and so misses out on a lot of the plant-associated vitamins and minerals.
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I've not seen any reports on clay, but I wouldn't expect as much. It's soil bacteria that produce the B12, so you're looking for organic-rich soils.
Animals that eat clay often do so to help neutralize toxic alkaloids and to get various mineral supplements.
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On the order of 15 micrograms per kilogram. [springer.com] Adult humans need 2.4 micrograms per day.
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Last summer my doctor diagnosed me as being vitamin B (and D) deficient. I wasn't aware of the source of B-12 previously, but it makes me wonder how I could be B-12 deficient as I am an omnivore, and not on a restricted diet. But as you say below, I am American, and so don't eat very healthily to begin with.
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He can still drink (unfiltred) beer [livestrong.com].
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Zymurgy is slavery! #YeastLivesMatter
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No it isn't. Schizophrenia is a hardware problem (though it can be triggered emotionally and/or with misc. drugs). While psychology is a hard problem to crack in general there are very strong evidence of the above and very little reliable evidence for the OPs idea.
Re: 'Schizophrenia' is a normal reaction... (Score:4, Insightful)
I would reverse that statement to read
"many schizophrenics suffer from homelessness"
Most have drug problems trying to combat the symptoms, nit the other way around.
You see the lies propagated in anti marijuana stories that cite " look, he's a schizophrenic because he smokes weed, when the opposite is closer to the truth, they are self medicating.
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Schizophrenia is a hardware problem (though it can be triggered emotionally and/or with misc. drugs).
In humans, the line between hardware and software is indelible. Or, you might just say that it's squishy and permeable.
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"indelible"? Huh?
Yeah, you're right. That's not the word I wanted. It's vaguely in the right ballpark, and I didn't sleep well. I wanted something about how they were in inseparable, and then a line got involved somehow...
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Schizophrenia is a hardware problem (though it can be triggered emotionally and/or with misc. drugs).
In humans, the line between hardware and software is indelible. Or, you might just say that it's squishy and permeable.
It would be better to think of the brain in terms of a FPGA because there is no higher ordered operating system software that is running on the hardware.
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It would be better to think of the brain in terms of a FPGA because there is no higher ordered operating system software that is running on the hardware.
Yes, I like that very much. Then again, what's on an FPGA (or in any other circuit) can be written down in terms of a software program...
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> Yes, I like that very much. Then again, what's on an FPGA (or in any other circuit) can be written down in terms of a software program.
This is demonstrably untrue for brains. Part of the key to a digital circuit, and program, is that it is deterministic. The same program run twice with the same nputs will produce the same output, and most of them can be modeled as Turing machines, so that they can be run on other hardware with sufficient resources.
I'm afraid that nerves are _analog_, with triggered cha
Re: 'Schizophrenia' is a normal reaction... (Score:2)
Yes, you can diagnose and even predict with brain imaging. Search Medline.
If there is another condition that's not visible on imaging then it's a separate disease, even if both are called the same thing clinically.
Re:'Schizophrenia' is a normal reaction... (Score:5, Informative)
Looks like someone doesn't know the difference between schizophrenia and multiple personality disorder. Also, the normal reaction to traumatic events is to black them out.
Why are ACs always make such total asses of themselves? ;)
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Why are ACs always make such total asses of themselves? ;)
Maybe schizophrenia?
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No, but that fake name is proper security procedure. The people using their real names on the internet are the odd ones.
https://thecybersafetylady.com... [thecybersa...ady.com.au]
Or are you intending to start posting under your own name instead of AC?
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https://www.nimh.nih.gov/health/publications/schizophrenia-booklet/index.shtml [nih.gov]
This post brought to you by the "Department o
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OMG, Nimh exists! Keep the rats away from them or there might be trouble.
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I thought the whole repressed memory thing was a complete myth. Aren't you way more likely to remember a traumatic memory than a mundane one?
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Nope. It's rare but it's how your brain copes with extreme trauma. [wikipedia.org] You are correct that you are likely to remember traumatic events but that just means that's your brain hasn't reacted to the trauma, it's treating them as normal events. The more intense the experience, the more neural connections, so the more you remember it.
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Well what have we here. Looks like I must update my mental definition of 'schizophrenia' based on what this AC said. Forget all the stuff about paranoid delusions, scary auditory and visual hallucinations, etc - it's "a description for a set of behaviours that are viewed as abnormal ALL caused by traumatic events during childhood".
Thanks AC. Can I quote you?
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But judging by the quality of your tap water, yeah most babies are born with PTSD right now. At least now we know this is entirely hereditary, luck of the drawer of sorts, but whats your excuse to don't even fucking know what schizophrenia is? feelings? trauma? These are people hallucinating shit 24/7, this is some brain malfunction where it literally flips the bird to your senses and proceeds to mix shit at random in the buffer bef
megavitamins (Score:3)
Both of these self anointed establishments' actions and statements then, when viewed by today's information, to me look like quacks with criminal intent
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Very large doses of some vitamins can actually make you very sick or significantly increase your cancer risk. The most common thing is people that think that LOTS of antioxidants are good for them. The problem is that if you take too many your body can no longer destroy cancer cells with free radicals generated by macrophages. If you take antioxidants too far you significantly increase your risk of cancer and your risk for bacterial infection.
There are also some fat soluble vitamins that are toxic if you ta
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Perhaps you should have provided some concrete details yourself, then.
He is right about the antioxidants. Research NRF2, from what I recall it is a negative feedback loop. The more Endogenous antioxidants you take the less exogenous antioxidants you make. This is bad because the bodies naturally produced antioxidants are better, in particular glutathione. Rather than taking endrogenous antioxidants, I recommend taking the prodrugs that your body needs to produce exogenous antioxidants. i.g. Acetylcysteine and Calcitriol (glutathione catalyst).
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The right doses with the right molecules is the key concept that naysayers are determined to miss. Any moron can skip the instructions and do something silly/stupid.
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There are also some fat soluble vitamins that are toxic if you take too much (like D).
Yes, in general fat soluble vitamins have a higher potential of toxic accumulation. But how toxic is it?
You can use about 50 000 IU per day for a long time with out symptoms.
Taking 50,000 international units (IU) a day of vitamin D for several months has been shown to cause toxicity. This level is many times higher than the Recommended Dietary Allowance (RDA) for most adults of 600 IU of vitamin D a day. http://www.mayoclinic.org/heal... [mayoclinic.org]
And even this information is old and the 600 IU RDA seams to be lacking. http://articles.mercola.com/si... [mercola.com]
New recommendations are at about 7 000 to 10 000 IU per Day with no access to sunlight at a UV-Index above 2.
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Add to that the fact that vitamins and natural supplements can't be patented. This creates an immediate bias against them when pharmaceuticals become available for similar symptoms. Drug companies are known to influence the Food and Drug Administration (FDA) and the medical community to discourage the public from using natural supplements when there are prescription drugs available.
Additionally, nobody can afford to invest the millions of dollars to prove the value of a particular vitamin, in the way that m
No "study find" (Score:2)
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So which B Vitamins exactly and in what dosages? Are there side effects at those dosages?
The articles specify B6, B8 & B12. As for the qty the article only specifies large doses which is clinically fucking useless.
Confidence Intervals... (Score:2)
Pooled effects showed that vitamin B supplementation (including B6, B8 and B12) reduced psychiatric symptoms significantly more than control conditions [g = 0.508, 95% confidence interval (CI) 0.01–1.01, p = 0.047, I2 = 72.3%]. Similar effects were observed among vitamin B RCTs which used intention-to-treat analyses (g = 0.734, 95% CI 0.00–1.49, p = 0.051).
The confidence interval indicates the level of uncertainty around the measure of effect (precision of the effect estimate). Confidence intervals are used because a study recruits only a small sample of the overall population so by having an upper and lower confidence limit we can infer that the true population effect lies between these two points. Most studies report the 95% confidence interval (95%CI). If the confidence interval crosses 1 that implies there is no difference between arms of the study. As
B-Complex is good generally (Score:2)
A B-Complex supplement is a good idea anyway, as B vitamins get peed out and don't stay in the body for too long.
So it is really hard to end up with not enough of them over a very short period of time and minor changes in diet can mean missing out.
B-12 is also depleted by certain medications like Metformin, one of the main Type 2 Diabetes treatments. If you take Metformin, you are automatically low on B-12 and you will need to take more every day. You cannot eat enough food to reach the level you need.
Cos
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B vitamins get peed out and don't stay in the body for too long.
B-12, one of vitamines mentioned, is stored in the liver for years.
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Smoking = nicotine = nicotinic acid? (Score:2)
And is smoking [slashdot.org] just a way of getting nicotinic acid as a byproduct (aka Niacin aka Vitamin B3)?
Vitamin B12 was recommended as a "rescue" for LSD (Score:2)