An anonymous reader sends this excerpt from Western University in Canada: "The first human applied clinical study (SAV CT 01) using a genetically modified killed whole-virus vaccine (SAV001-H) to evaluate its safety and tolerability was initiated in March 2012. This study is a randomized, observer-blinded, placebo-controlled study of killed whole HIV-1 vaccine (SAV001-H) following intramuscular (IM) administration. Infected men and women, 18-50 years of age, have been enrolled in this study and randomized into two treatment groups to administer killed whole HIV-1 vaccine (SAV001-H) or placebo. Sumagen announced today the patient enrollment has progressed smoothly and there have been no adverse effects observed including local reactions, signs/symptoms and laboratory toxicities after SAV001-H injection in all enrolled patients to date. With these interim results, the SAV001-H has proven safety and tolerability in humans and given Sumagen confidence for the next clinical trials to prove its immunogenicity and efficacy evaluation."
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kmoser writes "Everybody's favorite astrophysicist, Neil deGrasse Tyson, makes an appearance in upcoming Superman #14, in which Superman visits the Hayden Planetarium to view his original planet. Meanwhile, back in reality, DC Comics explains that NdGT has used his 'astronomical' powers to select the red dwarf LHS 2520 as the most likely real-life red star to fit with Superman's back story."
MrSeb writes "Engineers at the University of Michigan have created a pacemaker that is powered by the beating of your heart — no batteries required. The technology behind this new infinite-duration pacemaker is piezoelectricity. Piezoelectricity is is literally 'pressure electricity,' and it relates to certain materials that generate tiny amounts of electricity when deformed by an external force — which, in the case of the perpetual pacemaker, the vibrations in your chest as your heart pumps blood around your body. Piezoelectric devices generate very small amounts of power — on the order of tens of milliwatts — but it turns out that pacemakers require very little power. In testing, the researchers' energy harvester generated 10 times the required the power to keep a pacemaker firing. Currently, pacemakers are battery powered — and the battery generally need to be replaced every few years, which requires surgery. According M. Amin Karami, the lead researcher, 'Many of the patients are children who live with pacemakers for many years,' he said. 'You can imagine how many operations they are spared if this new technology is implemented.' This piezoelectric energy harvester is about half the size of a conventional battery, too, which is presumably a good thing."
kkleiner writes "Short on arable land? One solution would be to plan up. Singapore, a small country that imports most of its food, has now begun selling vegetables from its first vertical farm. And even while they're more expensive the vegetables are already selling faster than they can be grown. If the farms prove sustainable – both technologically and economically – they could provide a much desired supplement to Singapore's locally grown food and serve as a model for farming in other land-challenged areas."
Hugh Pickens writes "NASA reports that according to a study by Rebecca Martin and Mario Livio asteroid collisions may have provided a boost to the birth and evolution of complex life on earth delivering water and organic compounds to the early Earth and accelerating the rate of biological evolution with occasional impacts to disrupt a planet's environment to the point where species must try new adaptation strategies. 'Too many asteroids, and you've got an unrelenting cosmic shooting gallery, raining fiery death from above,' writes Fraser Cain. 'Too few asteroids, and complex life might not get the raw material it needs to get rolling. Life never gets that opportunity to really shake things up and evolve into more complex forms.' Martin and Livio suggest that the location of an asteroid belt relative to a Jupiter-like planet is not an accident. The asteroid belt in our solar system, located between Mars and Jupiter, is a region of millions of space rocks that sits near the 'snow line,' which marks the border of a cold region where volatile material such as water ice are far enough from the sun to remain intact. 'To have such ideal conditions you need a giant planet like Jupiter that is just outside the asteroid belt [and] that migrated a little bit, but not through the belt,' Livio explains. 'If a large planet like Jupiter migrates through the belt, it would scatter the material. If, on the other hand, a large planet did not migrate at all, that, too, is not good because the asteroid belt would be too massive. There would be so much bombardment from asteroids that life may never evolve.'"
An anonymous reader writes "4 years ago I read about experimental targeted muscle reinnervation (TMR) surgery on Slashdot. 3 years ago I crashed my motorcycle and had my leg amputated — at which time I had TMR done. Today I climbed 103 floors of the Willis Tower in Chicago with a experimental prosthetic using TMR. Thanks, Slashdot."
An anonymous reader writes with a link to this "time lapse video of students and postdocs at the University of Zurich constructing the zBox4 supercomputer. The machine has a theoretical compute capacity of ~1% of the human brain and will be used for simulating the formation of stars, planets and galaxies." That rack has "3,072 2.2GHz Intel Xeon cores and over 12TB of RAM." Also notable: for once, several of the YouTube comments are worth reading for more details on the construction and specs.
SternisheFan writes with an update to a story from earlier this year about a lawsuit in which David Coppedge alleged he was fired from NASA's Jet Propulsion Laboratory for his advocacy of Intelligent Design. Now, a judge has ruled that Coppedge was legitimately dismissed for performance reasons. From the article: "n 2009, he apparently got a bit aggressive about promoting these ideas at work, leading one employee to complain. The resulting investigation found that he had also aggressively promoted his opinion on California's gay marriage ban, and had attempted to get JPL's holiday party renamed to 'Christmas party.' ... Coppedge was warned about his behavior at work, but he felt it was an infringement of his religious freedom, so he sued. Shortly after, as part of a set of cutbacks on the Cassini staff, he was fired. In court, Coppedge and his lawyer portrayed him as being targeted for promoting an idea that is, to put it mildly, not popular with scientists. But JPL's legal team introduced evidence that his aggressive promotion of it at work was part of a pattern of bad interactions with his fellow employees that dated back at least five years earlier."
theshowmecanuck writes with this snippet from Canada's National Post: "Days after the remote B.C. archipelago of Haida Gwaii emerged virtually unscathed from Canada's second-strongest earthquake, locals discovered that the shifting earth had mysteriously switched off a centuries-old hot spring considered sacred by the Haida. ... A Parks Canada inspection party set out to investigate and stepped ashore to find that the island's three main hot spring pools, which once bubbled with water as warm as 77 Celsius, were bone dry. "Not even a small puddle," said Mr. Gladstone. Surrounding rocks, once warm to the touch, were cold." The earthquake measured 7.7 on the Richter scale."
astroengine writes "Using its robotic arm-mounted MAHLI camera, NASA's Mars rover Curiosity has snapped, quite possibly, the most iconic image to come from the mission so far. By stitching together 55 high-resolution photos, the rover has snapped an 'arm's length' self portrait, capturing its location in the geologically interesting area known as 'Rocknest,' including its recent scoop marks in the Martian soil and the base of Mt. Sharp." Note to NASA: Please sell this image in the form of a fundraising poster.
An anonymous reader writes "While New York University's Langone Medical Center in lower Manhattan was the site of heroism as 260 patients were evacuated from flooded floors and a nearly complete loss of power, similar floods at NYU's nearby Smilow Research Building killed thousands of laboratory mice, including genetically altered specimens in-bred over many generations as research subjects for melanoma and other diseases. Other laboratory animals, cells, and living tissue used in medical research were also lost; because of the gestation period involved, some projects were likely set back a number of years. Past experience with storms such as Allison in Houston and Katrina in New Orleans has shown that keeping laboratory animals in basements is not good practice, but research institutions keep doing it anyway."
cylonlover writes "The EU Commission's Community Research and Development Information Service (CORDIS) is working on a 'beaming' telepresence system that is designed to allow users to virtually experience being in a remote location by seeing, hearing and even feeling that location through the sensory inputs of a robot located there. That robot, in turn, would relay the user's speech and movements to the people at that location. Now, two of the CORDIS partners have put an interesting slant on the technology – they've used it to let people interact with rats."
Hugh Pickens writes "Lewis M. Cohen reports that this Election Day, Massachusetts is poised to approve the Death With Dignity Act, a modernized, sanitized, politically palatable term that replaces the now-antiquated expression 'physician-assisted suicide.' Oregon's Death With Dignity Act has been in effect for the past 14 years, and the state of Washington followed suit with a similar law in 2008. But the Massachusetts ballot question has the potential to turn death with dignity from a legislative experiment into the new national norm, because the state is the home of America's leading medical publication (the New England Journal of Medicine), hospital (Massachusetts General), and four medical schools (Harvard, Boston University, University of Massachusetts, and Tufts). If the act passes in Massachusetts, other states that have previously had unsuccessful campaigns will certainly be emboldened to revisit this subject. The initiative would allow terminally ill patients with six months or less to live to request from their doctor a prescription for a lethal dose of a drug. Doctors do not have to offer the option at all, and patients must make three requests, two verbal and one written. They must self-administer the drug, which would be ingested. The patients must be deemed capable of making an informed decision. 'It's all about choice,' says George Eighmey, a key player in instituting the Oregon law, defending it against repeal and shepherding it into reality. 'You decide. No one else can decide for you. No can can force you into it, coerce you into it or even suggest it to you unless you make a statement: "I don't want to live like this any more" or "I'm interested in that law out there, doctor, can you give me something to alleviate this pain and suffering."'"
derekmead writes "Batteries rule everything around us, which makes breakthroughs a big deal. A research team at Rice says they have produced a nice jump: by using a crushed silicon anode in a lithium-ion battery, they claim to have nearly tripled the energy density of current li-ion designs. Engineer Sibani Lisa Biswal and research scientist Madhuri Thakur reported in Nature's Scientific Reports (it has yet to be published online) that by taking porous silicon and crushing it, they were able to dramatically decrease the volume required for anode material. Silicon has long been looked at as an anode material because it holds up to ten times more lithium ions than graphite, which is most commonly used commercially. But it's previously been difficult to create a silicon anode with enough surface area to cycle reliably. Silicon also expands when it's lithiated, making it harder to produce a dense anode material. After previously testing a porous silicon 'sponge,' the duo decided to try crushing the sponges to make them more compact. The result is a new battery design that holds a charge of 1,000 milliamp hours per gram through 600 tested charge cycles of two hours charging, two hours discharging. According to the team, current graphite anodes can only handle 350 mAh/g."
MatthewVD writes "The National Hurricane Center reported today that the combined energy and duration of all the storms in the Atlantic basin hurricane season was 30 percent above the average from 1981 to 2010. At Weather Underground, Dr. Jeff Masters blogs that record low levels of arctic ice could have caused a 'blocking ridge' over Greenland that pushed Hurricane Sandy west. Meanwhile, Bloomberg BusinessWeek says, 'it's global warming, stupid.'"
cylonlover writes "Having successfully negotiated the challenging regulatory slopes of the U.S. Bureau of Land Management, the U.S. Forest Service, the U.S. Department of Energy, and a host of Oregon state agencies, the Newberry Enhanced Geothermal Systems (EGS) demonstration project is in the process of creating a new geothermal reservoir in central Oregon. The core of the new reservoir is a two mile (3.2 km) deep well drilled about four miles (6.4 km) from the center of Newberry Volcano. The rock surrounding the wellbore reaches temperatures in the order of 600 F (300 C), and is nearly impermeable to water. That, however, is about to change. Newberry Volcano is one of the largest and youngest volcanoes in the United States. Having last erupted about 1,300 years ago, it consists of over 400 individual volcanic vents, which, when combined, form a broad mounded landform referred to as a shield volcano. The Newberry EGS Demonstration geothermal reservoir is being formed in the high-temperature, low-permeability deep lava of the volcano's northwest flank."
terrancem writes "The Kihansi Spray Toad went extinct in the wild in 2005 when its habitat in Tanzania was destroyed by a dam. However conservationists at the Bronx Zoo managed to maintain a captive population which is now large enough to allow a bold experiment to move forward: reintroducing the toad into its old habitat. To make the once tropical gorge moist again, engineers have designed an artificial misting system that should allow toads to survive in the wild. The effort marks what may be the first time conservationists have ever re-established an 'extinct' species in a human-engineered ecosystem."
First time accepted submitter GrimAndBearIt writes "NASA's Curiosity rover is poised to settle years of debate on the question of atmospheric methane on Mars, which would be a sign of microbial life. With parts per trillion sensitivity, it's not so much a question of whether the rover will be able to smell trace amounts of methane, but rather a question of how much. NASA has announced that Grotzinger's team will discuss atmospheric measurements at a briefing on 2 November. If the rover has detected methane at sufficiently high concentration, or exhibiting temporal variations of the kind that suggests microbial activity, then it will surely motivate a desire to identify and map the sources."
Zothecula writes "For people who are unable to walk under their own power, exoskeletons offer what is perhaps the next-best thing. The devices not only let their users stand, but they also move their legs for them, allowing them to walk. While groups such as Berkeley Bionics, NASA, Rex Bionics, and ReWalk are all working on systems, Nashville's Vanderbilt University has just announced the development of its own exoskeleton. It is claimed to offer some important advantages over its competitors."
willith writes "I was recently given the opportunity to spend several hours on the floor of Historic Mission Operations Control Room #2, at the Johnson Space Center in Houston. MOCR2 was used to control almost manned Gemini and Apollo mission, including Apollo 11 & 13. More, my tour guide was none other than famous Apollo mission controller Sy Liebergot, one of the fellows behind the solution that saved Apollo 13. I go in-depth on the role of the flight controller during Apollo, and focus on how and why Mission Control functioned, and I spend a lot of time talking about the consoles and how they worked. The feature includes a ton of anecdotes and stories from Mr. Liebergot about mission control in general, and about what he did during Apollo 12 & 13 specifically. I also put together a supplemental report that goes through each and every station and describes their Apollo-era layout."