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Medicine

Scientists Engineer Cancer-Killing Stem Cells 2

Posted by Soulskill
from the stem-cell-rambo dept.
SternisheFan writes with news that medical researchers from Harvard Medical School and Massachusetts General Hospital have successfully cultivated stem cells that will kill brain cancer cells in mice without damaging healthy cells. "They used genetic engineering to make stem cells that spewed out cancer-killing toxins, but, crucially, were also able to resist the effects of the poison they were producing. ... In animal tests, the stem cells were surrounded in gel and placed at the site of the brain tumor after it had been removed. Their cancer cells then died as they had no defense against the toxins (abstract)." The next step in the research is to try the treatment on humans. Chris Mason, a professor of regenerative medicine, said, "This is a clever study, which signals the beginning of the next wave of therapies. It shows you can attack solid tumors by putting mini pharmacies inside the patient which deliver the toxic payload direct to the tumor. Cells can do so much. This is the way the future is going to be."
Star Wars Prequels

Peter Kuran:Visual Effects Artist and Atomic Bomb Archivist 24

Posted by timothy
from the everyone-should-have-a-hobby dept.
Lasrick links to this interview with Peter Kuran, an animator of the original Star Wars and legendary visual effects artist, writing If you saw the recent remake of Godzilla, you saw stock footage from Atom Central, known on YouTube as 'the atomic bomb channel.' Atom Central is the brainchild of Kuran, who among his many talents is an expert on archival films of the atmospheric testing era of 1945 to 1963. Combining his film restoration and photography expertise with his interest in nuclear history, he has also produced and directed five documentaries. He is currently working with Lawrence Livermore and Los Alamos National Laboratories to preserve and catalog images from the bomb-testing era, and to produce a technical handbook that will help people understand these images and the techniques used to create them.
Build

A Low Cost, Open Source Geiger Counter (Video) 43

Posted by Roblimo
from the be-sure-to-take-one-of-these-on-your-next-trip-to-chernobyl dept.
Sawaiz Syed's LinkedIn page says he's a "Hardware Developer at GSU [Georgia State University], Department of Physics." That's a great workplace for someone who designs low cost radiation detectors that can be air-dropped into an area where there has been a nuclear accident (or a nuclear attack; or a nuclear terrorist act) and read remotely by a flying drone or a robot ground vehicle. This isn't Sawaiz's only project; it's just the one Timothy asked him about most at the recent Maker Faire Atlanta. (Alternate Video Link)
Science

Recent Nobel Prize Winner Revolutionizes Microscopy Again 33

Posted by Soulskill
from the magnified-consistency dept.
An anonymous reader writes: Eric Betzig recently shared in the Nobel Prize for Chemistry for his work on high-resolution microscopy. Just yesterday, Betzig and a team of researchers published a new microscopy technique (abstract) that "allows them to observe living cellular processes at groundbreaking resolution and speed." According to the article, "Until now, the best microscope for viewing living systems as they moved were confocal microscopes. They beam light down onto a sample of cells. The light penetrates the whole sample and bounces back. ... The light is toxic, and degrades the living system over time. Betzig's new microscope solves this by generating a sheet of light that comes in from the side of the sample, made up of a series of beams that harm the sample less than one solid cone of light. Scientists can now snap a high-res image of the entire section they're illuminating, without exposing the rest of the sample to any light at all."
Science

Decades-old Scientific Paper May Hold Clues To Dark Matter 89

Posted by Soulskill
from the how-scientists-become-hoarders dept.
sciencehabit writes: Here's one reason libraries hang on to old science journals: A paper from an experiment conducted 32 years ago may shed light on the nature of dark matter, the mysterious stuff whose gravity appears to keep the galaxies from flying apart. The old data put a crimp in the newfangled concept of a 'dark photon' and suggest that a simple bargain-basement experiment could put the idea to the test. The data come from E137, a "beam dump" experiment that ran from 1980 to 1982 at SLAC National Accelerator Laboratory in Menlo Park, California. In the experiment, physicists slammed a beam of high-energy electrons, left over from other experiments, into an aluminum target to see what would come out. Researchers placed a detector 383 meters behind the target, on the other side of a sandstone hill 179 meters thick that blocked any ordinary particles.
Medicine

Stem Cells Grown From Patient's Arm Used To Replace Retina 55

Posted by Soulskill
from the you-and-what-arm-eye dept.
BarbaraHudson writes: The Globe and Mail is reporting the success of a procedure to implant a replacement retina grown from cells from the patient's skin. Quoting: "Transplant doctors are stepping gingerly into a new world, one month after a Japanese woman received the first-ever tissue transplant using stem cells that came from her own skin, not an embryo. On Sept. 12, doctors in a Kobe hospital replaced the retina of a 70-year-old woman suffering from macular degeneration, the leading cause of blindness in the developed world. The otherwise routine surgery was radical because scientists had grown the replacement retina in a petri dish, using skin scraped from the patient's arm.

The Japanese woman is fine and her retinal implant remains in place. Researchers around the world are now hoping to test other stem-cell-derived tissues in therapy. Dr. Jeanne Loring from the Scripps Research Institute in La Jolla, Calif., expects to get approval within a few years to see whether neurons derived from stem cells can be used to treat Parkinson's disease."
Medicine

Detritus From Cancer Cells May Infect Healthy Cells 45

Posted by samzenpus
from the one-bad-cell dept.
bmahersciwriter writes Tiny bubbles of cell membrane — called exosomes — are shed by most cells. Long thought to be mere trash, researchers had recently noticed that they often contain short, regulatory RNA molecules, suggesting that exosomes may be one way that cells communicate with one another. Now, it appears that RNA in the exosomes shed by tumor cells can get into healthy cells and 'transform' them, putting them on the path to becoming cancerous themselves.
Medicine

NY Doctor Recently Back From West Africa Tests Positive For Ebola 340

Posted by samzenpus
from the I-think-I-saw-this-movie dept.
An anonymous reader writes An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus, Mayor Bill de Blasio said. It's the first case in the city and the fourth in the nation. From the article: "The doctor, identified as Craig Spencer, 33, came back from treating Ebola patients in Guinea about 10 days ago, and developed a fever, nausea, pain and fatigue Wednesday night. The physician, employed at New York's Columbia Presbyterian Hospital, has been in isolation at Bellevue Hospital in Manhattan since Thursday morning, the official said."
Medicine

Leaked Documents Reveal Behind-the-Scenes Ebola Vaccine Issues 121

Posted by timothy
from the how-much-for-what-benefit-to-whom-with-what-certainty dept.
sciencehabit writes Extensive background documents from a meeting that took place today at the World Health Organization (WHO) have provided new details about exactly what it will take to test, produce, and bankroll Ebola vaccines, which could be a potential game changer in the epidemic. ScienceInsider obtained materials that vaccinemakers, governments, and WHO provided to the 100 or so participants at a meeting on 'access and financing' of Ebola vaccines. The documents put hard numbers on what until now have been somewhat fuzzy academic discussions. And they make clear to the attendees—who include representatives from governments, industry, philanthropies, and nongovernmental organizations—that although testing and production are moving forward at record speed, knotty issues remain.
Science

Oldest Human Genome Reveals When Our Ancestors Mixed With Neanderthals 127

Posted by samzenpus
from the how-you-doing? dept.
sciencehabit writes DNA recovered from a femur bone in Siberia belongs to a man who lived 45,000 years ago, according to a new study. His DNA was so well preserved that scientists were able to sequence his entire genome, making his the oldest complete modern human genome on record. Like present-day Europeans and Asians, the man has about 2% Neanderthal DNA. But his Neanderthal genes are clumped together in long strings, as opposed to chopped up into fragments, indicating that he lived not long after the two groups swapped genetic material. The man likely lived 7000 to 13,000 years after modern humans and Neanderthals mated, dating the mixing to 52,000 to 58,000 years ago, the researchers conclude. That's a much smaller window than the previous best estimate of 37,000 to 86,000 years ago.
Space

Two Exocomet Families Found Around Baby Star System 22

Posted by samzenpus
from the across-the-universe dept.
astroengine writes Scientists have found two families of comets in the developing Beta Pictoris star system, located about 64 light-years from Earth, including one group that appears to be remnants of a smashed-up protoplanet. The discovery bolsters our theoretical understanding of the violent processes that led to the formation of Earth and the other terrestrial planets in the solar system. "If you look back at the solar system when it was only 22 million years old, you might have seen phenomena that's a like more like what's happening in Beta Pic," astrophysicist Aki Roberge, with NASA Goddard Space Flight Center, Greenbelt, Md., told Discovery News.
Science

6,000 Year Old Temple Unearthed In Ukraine 109

Posted by timothy
from the imagine-the-sound-track dept.
An anonymous reader writes A massive archaeological dig of an ancient Ukrainian village first begun in 2009 has yielded a discovery that I sort of hope ends up inspiring a video game: a massive, scary-sounding temple. From the article: "Inside the temple, archaeologists found the remains of eight clay platforms, which may have been used as altars, the finds suggested. A platform on the upper floor contains "numerous burnt bones of lamb, associated with sacrifice," write Burdo and Videiko, of the Institute of Archaeology of the National Academy of Sciences of Ukraine. The floors and walls of all five rooms on the upper floor were "decorated by red paint, which created [a] ceremonial atmosphere."
Maybe this is what Putin has been after.
Space

Astronomers Find Brightest Pulsar Ever Observed 68

Posted by Soulskill
from the go-big-or-go-home dept.
An anonymous reader writes: Astronomers using the Chandra X-ray Observatory and the NuSTAR satellite have discovered a pulsar so bright that it challenges how scientists think pulsars work. While observing galaxy M82 in hopes of spotting supernovae, the researchers found an unexpected source of X-rays very close to the galaxy's core. It was near another source, thought to be a black hole. But the new one was pulsing, which black holes don't do. The trouble is that according to known pulsar models, it's about 100 times brighter than the calculated limits to its luminosity (abstract). Researchers used a different method to figure out its mass, and the gap shrank, but it's still too bright to fit their theories.
Space

What It Took For SpaceX To Become a Serious Space Company 95

Posted by Soulskill
from the gumption-and-elbow-grease-(and-piles-of-cash) dept.
An anonymous reader writes: The Atlantic has a nice profile of SpaceX's rise to prominence — how a private startup managed to successfully compete with industry giants like Boeing in just a decade of existence. "Regardless of its inspirations, the company was forced to adopt a prosaic initial goal: Make a rocket at least 10 times cheaper than is possible today. Until it can do that, neither flowers nor people can go to Mars with any economy. With rocket technology, Musk has said, "you're really left with one key parameter against which technology improvements must be judged, and that's cost." SpaceX currently charges $61.2 million per launch. Its cost-per-kilogram of cargo to low-earth orbit, $4,653, is far less than the $14,000 to $39,000 offered by its chief American competitor, the United Launch Alliance. Other providers often charge $250 to $400 million per launch; NASA pays Russia $70 million per astronaut to hitch a ride on its three-person Soyuz spacecraft. SpaceX's costs are still nowhere near low enough to change the economics of space as Musk and his investors envision, but they have a plan to do so (of which more later)."
Medicine

DHS Investigates 24 Potentially Lethal IoT Medical Devices 78

Posted by Soulskill
from the but-they're-fine-with-mcdonald's-so-don't-get-your-hopes-up dept.
An anonymous reader writes: In the wake of the U.S. Food and Drug Administration's recent recommendations to strengthen security on net-connected medical devices, the Department of Homeland Security is launching an investigation into 24 cases of potential cybersecurity vulnerabilities in hospital equipment and personal medical devices. Independent security researcher Billy Rios submitted proof-of-concept evidence to the FDA indicating that it would be possible for a hacker to force infusion pumps to fatally overdose a patient. Though the complete range of devices under investigation has not been disclosed, it is reported that one of them is an "implantable heart device." William Maisel, chief scientist at the FDA's Center for Devices and Radiological Health, said, "The conventional wisdom in the past was that products only had to be protected from unintentional threats. Now they also have to be protected from intentional threats too."

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