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+-   Antidepressants don't work better than a placebo-> on Tuesday February 26 2008, @04:53AM Matthew Whalley

Submitted by Matthew Whalley on Tuesday February 26 2008, @04:53AM
medicine
Matthew Whalley writes "These researchers got hold of published and unpublished data from drug companies regarding the effectiveness of the most common antidepressant drugs. Previously, when meta-analyses have been conducted on only the published data the drugs have been shown to have a clinically significant effect. However, when the unpublished data is taken into account the difference between the effects of drug and placebo becomes clinically meaningless (just a 1 or 2 point difference on a 30-point depression rating scale), except for the most severely depressed patients. Doctors do not recommend that patients come off antidepressant drugs without support, but this study is likely to lead to a rethink regarding how the drugs are licensed and prescribed."
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