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Biotech Beer Science

Synthetic Chromosomes Successfully Integrated Into Brewer's Yeast 107 107

New submitter dunnomattic writes: "Researchers at New York University School of Medicine have achieved a milestone in synthetic biology. A fully synthetic yeast chromosome, dubbed 'synIII,' has successfully replaced chromosome 3 of multiple living yeast cells. The researchers pieced together over 250,000 nucleotide bases to accomplish this feat. Dr. Jef Boeke, the lead author of the study, says, 'not only can we make designer changes on a computer, but we can make hundreds of changes through a chromosome and we can put that chromosome into yeast and have a yeast that looks, smells and behaves like a regular yeast, but this yeast is endowed with special properties that normal yeasts don't have.' Work is underway (abstract) to synthesize the remaining 15 chromosomes."
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Synthetic Chromosomes Successfully Integrated Into Brewer's Yeast

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  • Re:Next goals: (Score:5, Informative)

    by Daniel Dvorkin (106857) on Friday March 28, 2014 @12:37PM (#46603839) Homepage Journal

    Honestly, I think that fear is overblown. Vertebrate pathogens have had hundreds of millions of years of optimization in the most ruthlessly selective "laboratory" ever known, and while there are obviously some pretty deadly ones out there they haven't managed to wipe us out yet. Nothing we do in a lab is likely to come close, in terms of coming up with something that can spread wildly on its own.

    I used to work between a synthetic bio lab at one end of the hall and an infectious disease lab at the other. Ask which one scared me more.

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