Imagining the Post-Antibiotic Future 453
Hugh Pickens DOT Com writes "Health authorities have been struggling to convince the public that the threat of totally drug-resistant bacteria is a crisis. Earlier this year, British chief medical officer Sally Davies described resistance to antibiotics as a 'catastrophic global threat' that should be ranked alongside terrorism. In September, Dr. Thomas Frieden, the director of the U.S. Centers for Disease Control and Prevention, issued a blunt warning: 'If we're not careful, we will soon be in a post-antibiotic era. For some patients and some microbes, we are already there.' Now Maryn McKenna writes that we are on the verge of entering a new era in history and asks us to imagine what our lives would be like if we really lost antibiotics to advancing drug resistance. We'll not just lose the ability to treat infectious disease; that's obvious. But also: The ability to treat cancer, and to transplant organs, because doing those successfully relies on suppressing the immune system and willingly making ourselves vulnerable to infection. We'll lose any treatment that relies on a permanent port into the bloodstream — for instance, kidney dialysis. We'd lose any major open-cavity surgery, on the heart, the lungs, the abdomen. We'd lose implantable devices: new hips, new knees, new heart valves. We'd lose the ability to treat people after traumatic accidents, as major as crashing your car and as minor as your kid falling out of a tree. We'd lose the safety of modern childbirth. We'd lose a good portion of our cheap modern food supply because most of the meat we eat in the industrialized world is raised with the routine use of antibiotics, to fatten livestock and protect them from the conditions in which the animals are raised. 'And it wouldn't be just meat. Antibiotics are used in plant agriculture as well, especially on fruit. Right now, a drug-resistant version of the bacterial disease fire blight is attacking American apple crops,' writes McKenna. 'There's currently one drug left to fight it.'"
Re:terrorism! ha! (Score:2, Informative)
There is more money to be made on terrorism, and government is in the business of making money. In prioritizing funding, government will always direct the cash flow towards the opportunity which (1) cost the most, and (2) is the most easily exploited for personal gain.
Solving 80 percent of the problem (Score:4, Informative)
What is it with the livestock, that would do nothing to solve the problem, doctors give out antibiotics like there f'in candy to anyone and everyone.
It would do something to solve the largest part of the problem
Amount of antibiotics sold by manufacturers for use by food-producing animals: 13.1 million kilograms
Sold for use by people: 3.3 million kilograms
80 percent of antibiotics sold in the US go to increasing meat production from farm animals.
http://www.nytimes.com/2013/03/28/opinion/antibiotics-and-the-meat-we-eat.html [nytimes.com]
http://www.politifact.com/truth-o-meter/statements/2013/oct/15/louise-slaughter/rep-louise-slaughter-says-80-antibiotics-are-fed-l/ [politifact.com]
http://www.rodalenews.com/antibiotics [rodalenews.com]
Just because you are a vegan doesn't mean you should peddle some false information.
Just because you are an Anonymous Coward doesn't mean you should peddle some false information. There, fixed it for you.
Re:What will researchers do next (Score:5, Informative)
A likely cause of this drug resistance is use of antibiotics to increase growth rate in livestock. It has been recently shown that for certain livestock simple sanitation methods can be superior to the use of antibiotics. It is also likely that there are superior methods to antibiotics for all livestock,
To follow your profit motive, most of the antibiotics in the US, 80%, are sold for agriculture. While we can assume that antibiotics for agriculture are sold for less than human use, and so the pharmaceuticals firms will not go immediately bankrupt if agricultural uses are outlawed, we can assume the shock to the sector will be significant.
Given that antibiotics in humans has become a minor part of the business, it is not unreasonable to assume that researchers must find an alternative.
Comment removed (Score:5, Informative)
Re:Why did we become so dependant? (Score:5, Informative)
It's not that Origin of Species is exactly a new book. By the time we developed the antibiotics evolutionary biology was well understood.
Market forces vs. scientists sounding the alarm: “It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them There is the danger that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant.” -- Fleming while accepting his Nobel prize in 1945
Re:terrorism! ha! (Score:5, Informative)
How often are scrapes and cuts (or even car accidents) treated with antibiotics?
All the time. What do you think Neosporin has in it?
Re:terrorism! ha! (Score:5, Informative)
Ah, yes, since you've never needed it, nobody else will. MRSA is already killing more people in the US than AIDS.
Re:terrorism! ha! (Score:4, Informative)
Re:This is ridiculous (Score:4, Informative)
"Godsend" was the word I heard often used to describe them.
Sure, apocalypse now it ain't, but the way things are going, society as a whole will change drastically as a result of anti-biotics being superseded by evolution.
Re:terrorism! ha! (Score:4, Informative)
Re:terrorism! ha! (Score:4, Informative)
The problem isn't that if you don't treat scrapes or cuts with antibiotics that they will get infected and you will die.
The problem is that if a scrape or cut gets a serious infection you won't be able to treat it with antibiotics.
Obligatory car analogy:
Car Airbags. If they all suddenly vanished, most people probably wouldn't have a problem, many car accidents don't trigger them. But when you need them, they will save your life.
Re:Anecdotes aren't statistics (Score:4, Informative)
Careful with anecdotes, they aren't data.
Holy shit did you miss the point.