Video The Cryonics Institute Offers a Chance at Immortality (Video #2) 155
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Today's interviewee is Cryonics Institute (CI) Director Andy Zawacki, who takes Slashdot's Robert Rozeboom into the facility where they keep the tanks with frozen people in them. Yesterday, Rob talked with David Ettinger, who is both the group's lawyer and the son of CI founder Robert Ettinger. For those of you who are obsessed with the process of vitrification, here's a link to a story about The Cryonics Institute's 69th Patient and how she was taken care of, starting at the moment of her deanimation (AKA death). The story has anatomical drawings, charts, and color pictures of Andy carrying out the actual procedure. But Cryonics, while endorsed as a concept by numerous scientists, may not be as good a way to insure immortality as transplanting your brain into a fresh (probably robotic) body, as Russian billionaire Dmitry Itskov hopes to do by 2035. There are also many groups that claim to offer spiritual (as opposed to corporeal) immortality. Which method of living forever works best? That remains to be seen, assuming any of them work at all. Perhaps we'll find out after the Singularity.
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There really is nothing TO discuss because if they haven't come up with some magical potion that keeps 100% of the ice crystals from forming AND a way to unfreeze without damage all they are gonna end up with when they thaw it is mush anyway. The way it was explained to me its not the flash freezing that is the biggest problem, after all you dunk a head in liquid nitrogen and it'll flash freeze alright, the problem is in the thawing as THAT is where all the damage occurs.
Actually, it's typically done these days using organ vitrification, which prevents ice crystals from forming. For most crypoprotectants used in the process of vitrification, you are limited to one cell type one which it has best effect. The CI folks mostly try their best to preserve the brain without freezing damage, at the expense of some of the other cell types. This has been successfully used on laboratory animal organ transplants for mammalian livers, kidneys, and hearts; the first reference is a patent on the method of prepping the organ, which the second is a PubMed article case study dealing with a rabbit kidney vitrification and subsequent live transplant.
https://www.google.com/patents/US5723282 [google.com]
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781097/ [nih.gov]
There has also been some interesting work in the last 5 years using in Japan using a 0.01 mT magnetic field. This prevents ice crystals from forming. The technique was originally developed by ABI, a Japanese company using a technique they call the "Calls Alive System", for storing sushi at cryogenic temperatures without permitting formation of ice crystals by triggerning through the glass phase change without normal expansion you would typically have with ice. The technique is currently being used for long term storage of live teeth, and has shown some merit for other larger organs:
http://www.ncbi.nlm.nih.gov/pubmed/20478291 [nih.gov]
http://www.sciencedirect.com/science/article/pii/S0011224010000854 [sciencedirect.com]