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Medicine

New Drugs Trail Many Old Ones In Effectiveness Against Disease 230

Lasrick tips this report from Reuters: "Despite the more than $50 billion that U.S. pharmaceutical companies have spent every year since the mid-2000s to discover new medications, drugmakers have barely improved on old standbys developed decades ago. Research published on Monday showed that the effectiveness of new drugs, as measured by comparing the response of patients on those treatments to those taking a placebo, has plummeted since the 1970s. 'While experts agree that tougher trials and similar factors explain some of the decline in drugs' reported effectiveness, something real is going on here,' said Olfson. 'Physicians keep saying that many of the new things just aren't working as well,' and therefore prescribe antidepressant drugs called tricyclics (developed in the 1950s) instead of SSRIs (from the 1980s), or diuretics (invented in the 1920s) for high blood pressure instead of newer anti-hypertensives.'"
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New Drugs Trail Many Old Ones In Effectiveness Against Disease

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