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Science

Scientists Have Re-Cloned Mice To the 25th Generation 134

Posted by Soulskill
from the time-to-locate-jango-fett dept.
derekmead writes "Dolly's mere existence was profound. It was also unusually short, at just six years. But scientists in Japan announced yesterday they have succeeded in cloning mice using the same technique that created Dolly with more or less perfect results: The mice are healthy, they live just as long as regular mice, and they've been flawlessly cloned and recloned from the same source to the 25th generation. Researchers claim it's the first example of seamless, repeat cloning using the Dolly method—known as "somatic cell nuclear transfer" (SCNT)—in which the nucleus from an adult source animal is transferred to an egg with its nucleus removed. Until recently, the process was fraught with failures and mutations. But the team led by Teruhiko Wakayama, whose results were published today in the journal Cell Stem Cell, was able to create 581 clones from the same original mouse. Scientists, including Dolly's creator, have long felt the process was still too unstable—and too wasteful of precious eggs, given the failure rate—to be used on humans any time soon. But perhaps it's not so far off, after all."
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Scientists Have Re-Cloned Mice To the 25th Generation

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  • by Dahamma (304068) on Friday March 08, 2013 @03:54PM (#43119493)

    But from the Wikipedia entry the summary itself links to:

    A post-mortem examination showed she had a form of lung cancer called Jaagsiekte,[15] which is a fairly common disease of sheep and is caused by the retrovirus JSRV.[16] Roslin scientists stated that they did not think there was a connection with Dolly being a clone, and that other sheep in the same flock had died of the same disease.[14] Such lung diseases are a particular danger for sheep kept indoors, and Dolly had to sleep inside for security reasons.

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