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Medicine Science

HIV Vaccine Safe Enough To Pass Phase 1 Human Trials 141

Posted by Soulskill
from the good-work-folks dept.
An anonymous reader sends this excerpt from Western University in Canada: "The first human applied clinical study (SAV CT 01) using a genetically modified killed whole-virus vaccine (SAV001-H) to evaluate its safety and tolerability was initiated in March 2012. This study is a randomized, observer-blinded, placebo-controlled study of killed whole HIV-1 vaccine (SAV001-H) following intramuscular (IM) administration. Infected men and women, 18-50 years of age, have been enrolled in this study and randomized into two treatment groups to administer killed whole HIV-1 vaccine (SAV001-H) or placebo. Sumagen announced today the patient enrollment has progressed smoothly and there have been no adverse effects observed including local reactions, signs/symptoms and laboratory toxicities after SAV001-H injection in all enrolled patients to date. With these interim results, the SAV001-H has proven safety and tolerability in humans and given Sumagen confidence for the next clinical trials to prove its immunogenicity and efficacy evaluation."
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HIV Vaccine Safe Enough To Pass Phase 1 Human Trials

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  • So... (Score:2, Interesting)

    by Anonymous Coward on Tuesday November 06, 2012 @09:09PM (#41902175)
    The test for HIV tests for antibodies... So the human body already makes antibodies against HIV... So how are the antibodies for this vaccine different? *These* work? How?
  • by sandysnowbeard (1297619) on Tuesday November 06, 2012 @09:11PM (#41902199)
    Why is a vaccine useful to (and being tested on) someone already infected?
  • Re:Calling BS (Score:5, Interesting)

    by lowlymarine (1172723) on Tuesday November 06, 2012 @09:24PM (#41902289)
    It doesn't, but then again that isn't what this stage of testing was about. But hey, I get it - reading to the end of the first sentence of the summary is a lot of work. A busy man like you can't be bothered to invest that much time before rushing off to enlighten us with your genius commentary.
  • Re:Does that mean (Score:5, Interesting)

    by Anonymous Coward on Tuesday November 06, 2012 @09:28PM (#41902329)

    That's not the problem. Believe it or not, the problem is getting them to use it. My father has worked in Africa for more than 20 years now and there is a massive amount of distrust for this sort of thing among the native populations. Many average people even think this type of thing is a CIA plot to kill them off. With the things people have done to them over the centuries, I'm not terribly surprised, but there has been a lot of effort over the last few generations to fix that, and yet it still remains. It won't be easy to overcome.

  • by Anonymous Coward on Tuesday November 06, 2012 @09:30PM (#41902337)

    It is not found in mankind prior the last 100 years.

    In many ways you are misguidedly correct. If the governments of Europe did not initiate their heavy colonisation of Africa during the late 19th century, it is unlikely that AIDS would have ever spread outside of the remote areas of Africa where it orginated and would not likely be the pandemic problem that it is today.

  • Re:Does that mean (Score:2, Interesting)

    by Anonymous Coward on Wednesday November 07, 2012 @11:18AM (#41907773)

    Spending money would be one thing. We're spending debt, money we don't have.
    It's the same as charging to your credit card a thanksgiving meal to a homeless person, so that you can go home and eat a can of beans.

    I'm all for charity, but you have to take care of yourself first (take care of, not live in luxury.) The country needs to get out of debt before we continue all this foreign aid.

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