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Medicine

Majority of Landmark Cancer Studies Cannot Be Replicated 233

Posted by Unknown Lamer
from the scientists-at-work dept.
New submitter Beeftopia writes with perhaps distressing news about cancer research. From the article: "During a decade as head of global cancer research at Amgen, C. Glenn Begley identified 53 'landmark' publications — papers in top journals, from reputable labs — for his team to reproduce. Begley sought to double-check the findings before trying to build on them for drug development. Result: 47 of the 53 could not be replicated. He described his findings in a commentary piece published on Wednesday in the journal Nature (paywalled) . ... But they and others fear the phenomenon is the product of a skewed system of incentives that has academics cutting corners to further their careers." As is the fashion at Nature, you can only read the actual article if you are a subscriber or want to fork over $32. Anyone with access care to provide more insight? Update: 04/06 14:00 GMT by U L : Naffer pointed us toward informative commentary in Pipeline. Thanks!
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Majority of Landmark Cancer Studies Cannot Be Replicated

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If it smells it's chemistry, if it crawls it's biology, if it doesn't work it's physics.

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