Gamers Piece Together Retrovirus Enzyme Structure 149
An anonymous reader writes "Gamers have solved the structure of a retrovirus enzyme whose configuration had stumped scientists for more than a decade. The gamers achieved their discovery by playing Foldit, an online game that allows players to collaborate and compete in predicting the structure of protein molecules. After scientists repeatedly failed to piece together the structure of a protein-cutting enzyme from an AIDS-like virus, they called in the Foldit players. The scientists challenged the gamers to produce an accurate model of the enzyme. They did it in only three weeks."
But the gamers won't get any of the royalties (Score:2, Interesting)
I'm sure that, despite figuring out the protein structure, that the gamers won't receive any of the patent royalties that the patent will likely generate.
Re:Avoid SGC (Score:4, Interesting)
You've obviously never heard about Wikipedia's Poke'mon problem. At one stage, there was more about Poke'mon (as in, a ludicrously large amount more) on Wikipedia than there was about World War II.
Hence the creation of Bulbapedia. The Poke'mon Problem probably still holds though.
Have they fixed the awful music yet? (Score:4, Interesting)
Re:Excellent use of crowd-sourcing (Score:4, Interesting)
Several items to note on this:
- kudos to researchers for bringing in gamers to gain some understanding on solving tghis problem
- kudos to the FoldIt programmers for making this 3D structure puzzle a solvable problem. They also constantly refined the puzzle based on feedback from the gamers.
- Not mentioned so far is the incredible importance of finding a workable structure to the retroviral protease enzyme, and that the researchers noted the structure may provide the opportunity to be blocked. If so that would appear to this layman of a nearly universal cure for viruses that insert DNA into chromosomes. I may be overstating that but I don't think it's limited to AIDS.
- There are many other puzzles to be solved for cellular components from what I read. This is clearly one of utmost importance, but I imagine there are others to solve now.
- This reminds me from what I read of the widespread efforts of laymen participation in solving important mathematical puzzles in the 1500's to 1800's.
- I don't know about this having a real useful impact to primary education, other than wow interest factor, but seems to be something that could be ongoing challenges, real "games" to solve if you will, for some time to come. There are innumerable puzzles to be solved at this level.