Researchers Zero In On Protein That Destroys HIV 216
Julie188 writes with this excerpt from a Loyola University news release:
"Using a $225,000 microscope, researchers have identified the key components of a protein called TRIM5a that destroys HIV in rhesus monkeys. The finding could lead to new TRIM5a-based treatments that would knock out HIV in humans, said senior researcher Edward M. Campbell, PhD, of Loyola University Health System."
and the $225,000 figure is relevant? (Score:2, Insightful)
I wish they'd tell us the hair colour of the researchers too since it's probably just as relevant to the article.
Cheap microscope (Score:5, Insightful)
As a biologist, I have no idea why they're making such a big deal of it being a $225,000 deconvolution microscope. It's cheap compared with what most institutions have. Besides which is the fact that the microscope used isn't interesting. Any high(ish) resolution fluorescent microscope would have given you the same data. The interesting part is this TRIM5a. Let's see what happens with recombinant TRIM5a in animal studies.
Re:yea. (Score:5, Insightful)
If I had a nickel for every condom that broke on me, I could buy myself another pack of Condoms.
Wearing protection, while it helps, is not the best way to go about staying uninfected.
And no I'm not saying that Abstinence is the right choice either, I think I'd probably go insane. But you can, you know, develop relationships with people before sleeping with them, so theres that level of trust where you'll inform each other of any STD's or STI's. THATS the best way to stay clean while being sexually active.
I wear one because I don't want any unwanted pregnancies. Before you jump in with "Isn't she on the pill?" - Yes, she is. Theres 2 reasons for that, one being that there are always those rare cases where the pill isn't 100% effective. The other reason being that it shouldn't be entirely her responsibility. If the odds were one in 1000 while on either the pill or using condoms, both of us doing our part makes it a 1 in a million chance instead.
Re:Cheap microscope (Score:3, Insightful)
I think the idea is to show that some advances are not money dependent. It's interesting to see a development on the enzyme/protein field, it's encouraging and sounds like it's moving in the right direction.
Should be: (Score:4, Insightful)
"Using a big-ass microscope, researchers have..."
Re:yea. (Score:5, Insightful)
Even forming relationships to trust someone isn't foolproof. They could be an STD carrier and still not tell you. Or they may not even know themselves.
get ready for the resurgence of other STDs (Score:5, Insightful)
Once HIV is curable, people will find out the hard way that they never did come up with a cure for Herpes.
So now we just have to worry about... (Score:3, Insightful)
HPV
herpes
Hepatitis C
The last being the worst of them - but if a cure for AIDS is found, i'm sure HVC is right behind it - IIRC, they already use interferon and have a 50/50 success rate to put patients in remission (although the treatment is basically chemotherapy... so makes you feel like poop)
Re:So the FDA can sit on it (Score:4, Insightful)
You're right: We should burn down the FDA so that the wise and beneficient pharmaceutical companies can immediately cure all our diseases with their well-tested, totally safe, and 100% effective drugs that are never mis-marketed for the sake of profit.
Re:Oblig Rodney Dangerfield (Score:3, Insightful)
Um. Aids is fatal. Herpes is annoying. For some of us, it's not even that. There's just a *little* difference.
Re:yea. (Score:4, Insightful)
The problem stems from welfare being a federal program administered by the states. To continue to provide welfare funds to a state, the state must identify a certain percentage of absent fathers. This is so that welfare can be recovered from child support obligations. So, state legislation is passed defining the notion of a "legal father".
The usual assumption is that this is either a biological father, a legally adopting father, or a man that has publicly acted as a father figure to the child. But, the truth is more sinister: to catch the requisite number of "fathers", the laws are very lax on the process of service requirements: often the mother just has to provide an address, and paperwork is sent there. The man is usually clueless as to the claim, and his (statutorily short) window of opportunity to dispute it until it is too late. He finds out only when his wages are garnished.
Re:Oblig Rodney Dangerfield (Score:5, Insightful)
Nobody seems to give any credence at all to the idea that maybe the puritan values on sex have a parallel to the kosher laws of Judaism and even the deep-seated cross-cultural taboos on things like cannibalism and incest. The rules came about because they provided protection from dangers both immediate and long term.
The cultures who originated these rules may not have understood exactly why doing or not doing certain things prevented illnesses but through generations of trial and error they built up a set of superstitions that provided some meaningful protection. The advantage of the commandment/fiat format is that it is easily absorbed by young and undisciplined minds, so that even if they don't understand why they are doing something they do it anyway because they know that's what they should do.
When you remove this framing and try to treat children (and immature adults) as consistently rational thinking beings you end up with what is effectively a total disregard for important long-standing safety rules.