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Biotech Medicine Science

Researchers Restore Youthful Memory In Aging Mice 145

An anonymous reader writes "German neuroscientists made a breakthrough in 'age-related cognitive decline', a common condition that often begins in one's late 40s (especially declarative memory — the ability to recall facts and experiences). Their new study identifies a genetic 'switch' for the cluster of learning and memory genes that cause memory impairment in aging mice. By injecting an enzyme, the team 'flipped' the switch to its on position for older mice, giving them the memory and learning performance they'd enjoyed when they were young. Now the team ultimately hopes to recover seemingly lost long-term memory in human patients." The video, which explains the gene flipping mechanism, is worth a watch (2:18).
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Researchers Restore Youthful Memory In Aging Mice

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  • 42 (Score:5, Interesting)

    by Jhon ( 241832 ) on Tuesday May 18, 2010 @06:29PM (#32258816) Homepage Journal

    That's my age. I do notice tt takes just a wee bit more effort to cram more stuff in my head than it used to. Other than that, I still enjoy my ability to recall ridicules bits of obscure minutia that when viewed in total aren't enough to get me a good job, but are just enough to be annoying.

    Seriously, though. My ability to commit stuff to memory and recall it *IS* one of my marketable skills. And anything that can help prolong the decline is welcome news.

  • No joke... (Score:3, Interesting)

    by mollog ( 841386 ) on Tuesday May 18, 2010 @06:32PM (#32258856)
    I'm hoping they can bring this to the public sooner rather than later. It's not funny when you can't remember stuff the way you used to, it's a little scary. I accept that it's part of getting older, but I don't accept it happily.
  • by tsotha ( 720379 ) on Tuesday May 18, 2010 @06:34PM (#32258878)
    It's not clear to me a treatment for normal cognitive decline would necessarily be effective for Alzheimer's.
  • by IANAAC ( 692242 ) on Tuesday May 18, 2010 @06:53PM (#32259030)
    and while I do notice it takes a bit more effort to learn something new, once I do I can retain it without problems, provided I use the knowledge.

    Languages have always interested me (it's what I do for a living these days), and every couple years I try to learn the basics of another language. I find that as long as I exercise the newly learned skill/material, I'm OK (such as reading newspapers in the other language, listening to broadcasts in that language, and finally speaking the language whenever I get the chance. I would imagine I'm using a different part of the brain for these activities, though.

    I'm certainly no expert, nor do I claim to know anything of how the mind works for that matter, but I can't help but think that actually using skills learned later in life helps.

  • by Minwee ( 522556 ) <dcr@neverwhen.org> on Tuesday May 18, 2010 @07:32PM (#32259308) Homepage
    Nov 21 - I did a dumb thing today I forgot I wasnt in Miss Kinnians class at the adult center any more like I use to be. I went in and sat down in my old seat in the back of the room and she lookd at me funny and she said Charlie where have you been. So I said hello Miss Kinnian Im redy for my lessen today only I lossed the book we was using.
  • by maxwell demon ( 590494 ) on Tuesday May 18, 2010 @07:42PM (#32259388) Journal

    Actually it's co-orelation. Orelation is the raw material from which irony is made. That is, it's something which isn't quite irony, but out of which one could make irony. Co-orelation is when several people orelate together. :-)

  • by blue trane ( 110704 ) on Tuesday May 18, 2010 @08:33PM (#32259684) Homepage Journal

    The point of civilization is knowledge. Knowledge allows us to predict and adapt to sudden catastrophic environmental change, hence it improves our survival fitness. Economics is just a way to increase knowledge.

    If economics is a science, how well does the current model predict economic downturns, or Japan's having a 200% debt-to-gdp ratio but no inflation, low unemployment, and a strong currency?

    The current model of economics appears to include an axiom: the creation of money should be in private hands. Can we challenge this axiom, given examples such as Japan, or our own history (Lincoln printing greenbacks, govt making up over 40% of GDP during WWII, inflation not much of a concern during Reagan's run-up of the debt, etc.)? Is it not suspicious that the main proponents of the current economics are the beneficiaries of a system where banks have a monopoly on money creation? Why can't the people's elected representatives create money too?

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