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Science

New Antifreeze Molecule Isolated In Alaskan Beetle 108

Arvisp writes with the news of a recently discovered antifreeze molecule in an Alaskan beetle that departs from most commonly identified natural antifreeze. "'The most exciting part of this discovery is that this molecule is a whole new kind of antifreeze that may work in a different location of the cell and in a different way,' said zoophysiologist Brian Barnes, director of the University of Alaska Fairbanks Institute of Arctic Biology and one of five scientists who participated in the Alaska Upis ceramboides beetle project. Just as ice crystals form over ice cream left too long in a freezer, ice crystals in an insect or other organism can draw so much water out of the organism's cells that those cells die. Antifreeze molecules function to keep small ice crystals small or to prevent ice crystals from forming at all. They may help freeze-tolerant organisms survive by preventing freezing from penetrating into cells, a lethal condition. Other insects use these molecules to resist freezing by supercooling when they lower their body temperature below the freezing point without becoming solid."
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New Antifreeze Molecule Isolated In Alaskan Beetle

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  • Re:I for one... (Score:1, Insightful)

    by maxume ( 22995 ) on Monday December 21, 2009 @06:59PM (#30518018)

    Just wear boots and step on them.

  • Re:Cryogenics? (Score:5, Insightful)

    by idontgno ( 624372 ) on Monday December 21, 2009 @07:00PM (#30518026) Journal

    if the cells remained intact, reviving them would become possible.

    Well, no more impossible than reviving them shortly after death, without the complications and damage (subtle or extreme) caused by freezing, or decapitating and freezing, or post-mortem whatnot.

    I think the greater obstacle is the entire "reviving them after they're dead" bit.

  • Re:Cryogenics? (Score:4, Insightful)

    by wizardforce ( 1005805 ) on Monday December 21, 2009 @07:02PM (#30518052) Journal

    Rapid freezing of tissue should act in a similar fashion. THe problem of course is being able to freeze tissue at the rate required to form the glass-like phase of ice. I suspect that this antifreeze molecule may work in cryogenic preservation if it shows low toxicity/immune response from the host. Something to keep in mind about frozen tissue as well is the fact that even at these extremely low temperatures, chemical reactions that degrade the sample still occur so there is a limit to how long even the most sturdy cells (like cancer cells) can be stored. If the tissue is frozen for too long of a time, revival may prove to be unlikely or even impossible.

  • Re:Cryogenics? (Score:3, Insightful)

    by Tubal-Cain ( 1289912 ) on Monday December 21, 2009 @07:10PM (#30518134) Journal

    I think the greater obstacle is the entire "reviving them after they're dead" bit.

    It would still have practical applications, such as for long trips through space.

  • Re:Cryogenics? (Score:3, Insightful)

    by __aagmrb7289 ( 652113 ) on Monday December 21, 2009 @08:19PM (#30518666) Journal
    Not so much. We revive people "after they are dead" all the time - and they are significantly less healthy than a specimen frozen using cryogenics (theoretically, of course). The obstacles are that the cells must return to normal structure after being safely thawed. At that point, shocking the heart into action will return blood-flow to normal, along with helping the lungs to get started - thus getting oxygen circulating in the system and avoiding cells dying due to that cause. Once that's avoided, IF ALL CELLS ARE HEALTHY, the person is alive and in reasonably good shape.
  • Re:Cryogenics? (Score:5, Insightful)

    by greyhueofdoubt ( 1159527 ) on Monday December 21, 2009 @08:35PM (#30518738) Homepage Journal

    This opens up a really gray area in terms of medical ethics. Here:

    There are many documented cases of people being revived after prolonged (over one hour) 'death' caused by exposure to cold with few side-effects. However, and this is a BIG however- those people were "killed" by the cold; that is, they did not fall victim to leukemia and suddenly die, falling into icy water.

    So...

    The obvious(?) answer is to freeze people who are *near* death. Well, that's kind of murder/euthanasia according to the laws on the books. Without that particular issue, yeah, this would work great. But we'd have to come to accept this as preservation instead of euthanasia. We could work it until the chances of coming out of it alive were the same as surviving open-heart surgery or something comparable, but I think there would still be that mental/emotional block. Not to mention that critically-ill/hospice patients are already fragile. "Gramp is still alive but we're going to freeze him," still has a funeral feel. The person is, in effect, dying until revived when whatever criteria were met. If we don't cure cancer (for example) in our lifetime, then that *is* a funeral for the patient's family and friends.

    -b

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