Gene Therapy Cures Color-Blind Monkeys 197
SpuriousLogic writes "After receiving injections of genes that produce color-detecting proteins, two color-blind monkeys have seen red and green for the first time. Except in its extreme forms, color blindness isn't a debilitating condition, but it's a convenient stand-in for other types of blindness that might be treated with gene therapy. The monkey success raises the possibility of reversing those diseases, in a manner that most scientists considered impossible. 'We said it was possible to give an adult monkey with a model of human red-green color blindness the retina of a person with normal color vision. Every single person I talked to said, absolutely not,' said study co-author Jay Neitz, a University of Washington ophthalmologist. 'And almost every unsolved vision defect out there has this component in one way or another, where the ability to translate light into a gene signal is involved.' The full-spectrum supplementation of the squirrel monkeys' sight, described Wednesday in Nature, comes just less than a year after researchers used gene therapy to restore light perception in people afflicted by Leber Congenital Amaurosis, a rare and untreatable form of blindness."
biotech rocks (Score:2)
nuff' said
Re:biotech rocks (Score:5, Funny)
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Re:biotech rocks (Score:4, Interesting)
Ditto here. I saw the article at discovery dot com today, and read it. Man, it would be GREAT to get a shot or six, and start seeing all those colors people SAY that they see. I could swear that people are involved in a conspiracy to convince people like me that we're nuts. Purple, lilac, lavender, and a whole lot of others are ALL THE SAME!!
Oddly enough, the little sample color vision chart they stuck in the article? I was able to see the eye in it. Not real clearly, but when I read the tag caption, I was able to see the eye. The real charts just don't work, though.
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I've been looking for geeky posters to add in my classroom for when I become an elementary/primary school teacher. Aside from a picture of Gandalf with the text "If you do not study, you shall not pass!", I now have another to add to the potential collection of wallgeekery. :3
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I prefer not to know. Igneous is bliss.
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Gneiss one.
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The World will one day be run by those damn dirty apes and they'll enslave us!
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Well, so long as they keep their stinking paws off me, I for one welcome our new simian overlords!
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Orangutans and chimpanzees ARE apes.
I DARE you to say that to their faces!
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I'm colour blind myself. (Seriously).
I'm currently looking around for a cheap monkey suit. I have my own supply of bananas.
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I'd wait until they find a way to make it work without injecting the viruses into your eyes. I haven't been following gene therapy or viral transfection, I'm assuming there's still the problem that these viruses still insert their genes into your genome at random, potentially interrupting, say retinoblastoma [wikipedia.org]. I think if that happened you'd be many times more likely to develop the cancer the protein is named after [wikipedia.org].
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Yeah, I know. It's just really exciting. I am genuinely colour blind and the possibility of seeing PROPER colours, like everyone else, is really exciting.
Of course ultimately pointless. I can genuinely say my colour blindness has never caused me any problems. It's limited my job choices a couple of times, but that was minor really.
Still, sure would be cool to see stuff properly. I mean grass is green, I know that. But what I see as green is vastly different to what other people see.
Be nice to see what grass
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...possibility of seeing PROPER colours...
Even more than that, it opens it up for everybody else to see in TRUE color, seeing as how even we color-advantaged folk only see a tiny sliver of the EM spectrum.
Could you imagine being able to see halfway down the IR spectrum, or well past UV on the other end? Things would look very different, that's for sure. Even just a little bump in both directions would be amazing.
Re:biotech rocks (Score:5, Informative)
> Could you imagine being able to see halfway down the IR spectrum, or well past UV on the other end
IR might be do-able, but UV is almost structurally impossible for the human eye to meaningfully view. The spectral peak of "blue" cones is actually closer to violet than blue. If you look at a sensitivity curve for human blue cones, you'll notice that its peak is just slightly above violet, and its lower third is simply chopped off or attenuated away. The problem is the cornea -- it blocks most UV light. What the cornea doesn't block, the fluid inside the eye absorbs and scatters. There have been reports that people who've had cataract surgery are able to perceive UV as hazy, diffuse "purplish-yellow" light. The idea that something can be purple and yellow is strange, but not as crazy as it sounds when you consider that the color we call "purple" is NOTHING like spectral violet, and is actually an artifact of human vision caused by a nonlinear slope in blue sensitivity. There's a tiny area where the upper end of blue overlaps with the lower end of red, with a small ripple in blue that introduces just enough error in that region to make purple possible.
There's another problem: chromatic aberration. Ever notice that you can make a fake 3d-like pic using pure red and pure blue, so the blue parts seem to be floating in space compared to the red? That's chromatic aberration at work. The cornea can only focus light from a relatively narrow band. The lower you go, the less-focused the light would be. Similar distortion would become problematic in the infrared range, though not as quickly as at the blue end.
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That is awesome. I'd never realized that purple is an artifact of our genes, not of the em spectrum. But really, using gene therapy to be a pentachromat would be amazing. You wouldn't even need a thermometer to see how hot the roast is, it'd just have to have the right tint. Maybe even dark thermographic vision.
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I'd be happy to see in IR, but I'd undergo treatment to become a tetrachromat [wikipedia.org]. That seems a little more likely, since there seem to be people who are tetrachromats.
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The problem is the cornea -- it blocks most UV light.
Key word "most". [wikipedia.org] If you had cones the right size you would indeed see UV.
You couldn't see UV if your eyeglass lenses
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After all, if an ape can learn to see a colour it has never seen before, and people can learn to see with their tongues, I figure given some suitable tech the brain can learn to support extra video ins.
If that's not possible for adults, but only for children, oh well...
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Are you color "blind", or color "deficient". I can't see much of the red and green spectrum, but yellow and blue are just fine. A far smaller number of people can't see yellow and blue, but they are alright with reds and greens. It's a very rare individual who is "color blind".
If you are really color blind, I feel for you. Damned road signs and traffic lights must be real killers. They're bad enough for me!
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Yes, it does. It's too late for my dad, though.
Yes it is.
My dad got a job at Union Electric in the early fifties when I was a toddler. He wanted to be an indoor wireman, but to be an indoor wireman you have to be able to tell a red wire from a green wire, and he can't. He became a lineman instead, and has been retired for about twenty years now.
When they changed the color of stop signs form yellow to red around 1960, it put him and y
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I wonder if they could use this gene therapy to give certain color-detecting genes to cats, to give them full color vision. Cats are partially color-blind naturally, so if they could give cats something that none of them are born with, and it works, there's no telling what kind of wacky things they could add onto living humans, like UV vision, fluorescing skin, poison fangs, etc.
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It wouldn't necessarily be an advantage. People with colourblindness also often have the secondary effect that they have far better night vision than someone with normal colour vision. I would image it is much the same with cats.
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Actually, I know you're joking but I wasn't even thinking of anything like that, as I've never seen that horrible movie. The fluorescing skin was from some Slashdot article I remember a while back, where they, I believe, made some mutant pigs with genes from some sea animal causing it to have fluorescing skin. And the poison fangs is probably because I live in Arizona and we're surrounded by rattlesnakes and scorpions. I have to catch a scorpion every few days in my house, now that it's summertime (they
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Shockingly enough, people are willing to take larger risks to solve more serious problems, and for most of the people who object to GM crops, some previously incurable disease is a much larger problem than food supply, which is already good and solved if you have the money.
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Shockingly enough, people are willing to take larger risks to solve more serious problems, and for most of the people who object to GM crops, some previously incurable disease is a much larger problem than food supply, which is already good and solved if you have the money.
Disclaimer: I easily might not know what I'm talking about here, and as a (non agricultural) biologist myself, I'm probably skewed opinion towards the "we can improve on nature without serious consequence" end of things.
We do have enough food I guess, and we do have advanced ways of making that much food. It would be great if the cost of GOOD food came down, if we could make the food better, and if we could get away from some agriculture methods, assuming the risk was low enough.
You can get all the calorie
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I just don't think that it is either surprising or particularly ironic that someone who opposes GMO food production would seek genetic treatment for a condition affect
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I see that I did go off on a tangent there when you weren't actually advocating that viewpoint.
I will point out that, especially with the viral method of transfection, you'd be much more likely to get cancer from this rather than GMO. I'm optimistic that if someone were offering to cure colorblindness by this method, someone would point out that and buisiness would dry up as people weigh the risks. I'm less optimistic that if they figure out how to do gene therapy without viral transfection or increased r
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And GM crops solve tons of problems though I think there should be room for two markets. The problem I have isn't people fighting for the choice of natural foods in their supermarket but fighting to stop GM crops. The threat of other people in your city eating GM crops is infinitesimally low.
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The problem non-GM croppers have (I'm not one of them, btw, I say it's about damn time we had killer tomatoes!), is GM crops almost always genetically compatible with non-GM crops, and most GM crops don't lose the ability to procreate.
In other words, if there is an "organic" (what a bullshit term, btw, if it weren't organic we couldn't eat it!) non-GM farm sitting next a GM farm, within a few years the non-GM farm will become a GM farm at least in part and the farmer may not even realize it. Well, until he
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for most of the people who object to GM crops, some previously incurable disease is a much larger problem than food supply
GM crops aren't going to solve hunger. There is more than enough food grown to feed everyone even without GM. The problem is with economics and greed.
My only beef against GM crops is I don't think one should be able to patent a life form.
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Sure will be fun watching all those people who won't eat a GM tomato line up for gene therapy that fixes the particular problem they have...
... i know... the ignorance amazes.
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A lot of people objecting to GMO don't do it for personal safety. They fear the possible contamination of natural ecosystems, or just dislike the importance it gives to firms which are not really known for their philanthropic behavior (for example, the possibility of seeds producing sterile plants so you have to buy them each year).
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It's not seeds that produce sterile plants that is the problem, the little guys will just continue to use reproducing plants. They get subsidies here in the US so it's no big deal for them one way or the other.
It's the repdroducing GM plants that are the problem, because most of the time they WILL reproduce with non-modified plants, and the result is a modified plant. You can't go back to non-modified once it is modified, it will forever be "changed".
I don't think it's a bad thing, as long as we take care
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GM foods? Hmmm. I object to GM foods for a couple of reasons, IN ADDITION to simple queasiness.
First, the GM foods are replacing a number of cultivars. A widely varied pool of genes, nationwide and world wide are being replaced with a monoculture. Never a good idea. One blight that affects the favored cultivar can ensure widespread hunger, and possibly starvation.
Second, man evolved as an omnivore. We take nourishment from almost anything and everything that doesn't take nourishment from us first. In
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Your arguments against monoculture and possible parent abuse are valid, but remember, a tool is only as good as you use it. Genetic engineering is a tool, just like any other branch of engineering, and GMOs and monoculture/patent trolling need not be mutually inclusive. Given time, hopefully we'll see a wide variety of GMO crops grown, and better patent laws, to avoid those problems.
Colors - for the first time (Score:4, Funny)
Re:Colors - for the first time (Score:4, Funny)
Given those results, I say we give the human trials a green light!
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Given those results, I say we give the human trials a green light!
Just make sure the people running it aren't red/green colorblind.
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Given those results, I say we give the human trials a green light!
We already did. Can't you see it?
This is great! (Score:4, Funny)
Now all those poor monkeys will finally be able to get unrestricted pilot licenses!
Next step: Tetrachromatism (Score:3, Interesting)
What about those crazy women with 4 color receptors [tomes.biz]. They are real life mutants! Are we going to get some gene therapy like that? I want 2 receptors for green! I'll be like a human HDTV! In fact, that will be my crimefighting name: The Human HDTV! I fight crime in 1080i! (it would be in 1080p but that's as high as my TV goes)
Re:Next step: Tetrachromatism (Score:5, Interesting)
Why not go infra-red? From the article..
Williams, however, was quicker to speculate. âoeUltimately we might be able to do all kinds of interesting manipulations of the retina,â he said. âoeNot only might we be able to cure disease, but we might engineer eyes with remarkable capabilities. You can imagine conferring enhanced night vision in normal eyes, or engineering genes that make photopigments with spectral properties for whatever you want your eye to see.â
âoeThis study makes that kind of science fiction future a distinct possibility, as opposed to a fantasy,â continued Williams.
Aye. A story deserving of being /.
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They can already bring a normal eye to better than 20/20 vision. Almost all baseball players heve LASIK surgery these days, and I have an implant in my left eye that gives me 20/16 vision. Unfortunately the other eye is still 20/400.
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Why not go infra-red?
Cool idea... your TV remote would look like an awesome torch. :)
Re:Next step: Tetrachromatism (Score:4, Insightful)
What about those crazy women with 4 color receptors [tomes.biz]. They are real life mutants! Are we going to get some gene therapy like that?
I'm not sure I would want that.
All color movies and photographs up now are recorded for a audience of tricromats. Watching movies, seeing your family pictures, browsing the internet etc would probably look poor to tetracromats.
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So? Glasses to filter out all but visible light (today's visible light) should be trivial. Just like those blue & red 3D glasses.
Re:Next step: Tetrachromatism (Score:4, Informative)
> So? Glasses to filter out all but visible light (today's visible light) should be trivial. Just like those blue & red 3D glasses.
Women believed to be tetrachromatic don't see light trichromats can't see... they recognize two variants of "green" as being different, the same way green and red are different to you. If you were genuinely tetrachromatic in the sense the women are believed to be, TV, film, photographs, and printed images would almost ALWAYS look like shit to you, because the "green" would be "wrong" in ways you couldn't really explain.
Here's an example: suppose you were a trichromat, living in a world where 94% of the population couldn't distinguish between red and green, and for all intents and purposes "yellow" was just a darker or brighter shade of red/green. Color film wouldn't be based on red, green, and blue... it would be based on blue and yellow. Your RGB monitor would be a BY monitor. To everyone else, the whole idea of "RGB" would be silly, because they could get the exact same image quality from just blue and yellow. You'd be the unfortunate person who kept babbling about there being a difference between "red" and "green", and that they were somehow different from the color everyone else knew as "yellow". Anyway, getting back to the example, a tetrachromatic woman wouldn't want RGB... she'd want RGgB, where "G" and "g" were slightly different frequencies of green. An RGB monitor to a tetrachromat would look just as artificial, fake, and bad as a Blue-Yellow monitor designed for deutranopes and protanopes would to you.
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> First of all, do you think tetrachromats know they perceive colors differently?
Actually, yes. I read about an interview with a British woman who's believed to be a genuine tetrachromat. One thing that came up was the fact that color photographs and TV never look "right" to her. Prior to learning about tetrachromaticy, she always just thought she was "picky".
The 20-bit example is a good one. I'm actually trichromanomalous. In terms that make sense to most Slashdotters, most people with statistically nor
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Not as poor as black and white television would look to people who can see in more than black and white.
A story from a while back [slashdot.org] showed that people who watched black and white TV as kids still often have monochromatic dreams. That to me suggests the brain might handle stepping DOWN in number of colors without much complaint. I'd be more concerned with "would the increased range of colors be extremely distracting, or cause seizures in those of us who have lived without 4 color channels?" It might be cons
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Something makes me suspicious... oh yeah:
I have no knowledge of which labs are trustworthy or whatever but that sentence demands skepticism
Programming Implications (Score:3, Funny)
This definitely has programming implications for me. If you ever have had to design web pages for a superior with color blindness, and they insist on choosing or refusing the colors you want to use, you know the programming problems that color blindness can cause.
"This page looks best after gene therapy" - hmm, I like it.
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Isn't that special (Score:2)
Color blind chimps everywhere rejoice.
Cerebral achromatopsia (Score:4, Interesting)
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Oh, shit! I bordered up myself in my house, held off the zombie cops and all the other zombies - for nothing?! They weren't zombies?! I'm the crazy one?!
Nah. Back off you zombies!!!
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Whoa. From the Wiki article, it sounds like this condition renders one incapable of even imagining color in visual imagery, not just seeing it.
Re:Cerebral achromatopsia (Score:5, Insightful)
That is so cool. I love that some people don't even realize they're seeing grey. They can still name colors perfectly fine (they can pick out the "blue flavored" gatorates in the supermarket at a glance), but they don't have the experience of color available to their consciousness. This sort of deconstruction of consciousness's functions is, IMO, the strongest evidence against Cartesian dualism.
This reminds me of an experiment Bill Nye did. He wore a pair of goggles that flipped his vision upside-down. After a few days (I think) of headaches he completely got used to it and was able to function normally with it upside down. I think I remember him saying that it didn't seem upside down to him, and when they took off the goggles at the end the world seemed upside down again. The really fascinating part was that there wasn't a moment of "flipping" during the experiment: the upside-down image became his expected norm. In other words, the optic nerves don't correspond directly to some raster format where they're tied directly into our Video In consciousness jack. They're interpreted as needed and presented to our consciousness experience post-processing.
And the simple experiment didn't prove this but I suspect that there's no relative relation between optic nerves either. Like they're just haphazardly bundled together and shipped off to the brain, and the brain's processing adaptively grows to sort and make sense of the random signals. So I suspect that if you sever the optic nerve and connect the nerves randomly your brain will eventually be able to just interpret the new signals as the norm like Bill Nye did.
The reason I suspect that is because of the really cool electronic sensing technology that's been developed in the last few decades. I think I've read something like they can just send signals into nerves (obviously with sensible modulation/frequency/amplitude) and make the signals vary in some way based on the external world and after awhile patients are able to sense it naturally. Like audio signals to the eardrums and such.
Oh yeah I found it. This [slashdot.org]. By just shocking areas of the tongue a blind patient can develop a kind of sight. If the top left pixel is dark you shock the top left area, etc. Again, I think that you could completely mix up all of the inputs and after awhile it would be perfectly natural.
Think of feeling with your hand. A priori you have no idea which nerves in that thick bundle of nerves correspond to a particular finger. But by observing and noticing that when you twitch a certain way a particular finger moves and when you touch something you get an input only on particular nerves you eventually build up an intuitive grasp of which nerve is which (handled transparently of course). The problem is complex and we see side effects all the time. I'm sure everyone's had the experience of being in a weird position with their arms or legs twisted up and you can't really tell which limb is which. You may experimentally try to move a particualar leg that you see and move the wrong one!
This whole field is fascinating
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"That is so cool. I love that some people don't even realize they're seeing grey."
I really don't think that you've read enough, or else that you have failed to understand what you have read.
I have both red and green color deficiency. My world is not gray. I see gray, as a distinct color, and I can see many shades of grey.
Instead of seeing gray where you see a shade of green, I see green. I am unable to distinguish very many shades of green - they sort of blend together. Where you might see 12 different
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There are some nature paintings from color-blind people. Those are very enlightening, they don't look like nature at all for non-color blind people like me.
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There are some nature paintings from color-blind people. Those are very enlightening, they don't look like nature at all for non-color blind people like me.
My parents first discovered my color blindness when I was in kindergarten. I came home with a crayon drawing of my gerbils, in which I had captured them with in yellow-green. To me that looked more or less correct, or the best I could do with the Crayola 64 box. So imagine a world in which gerbils are more or less yellow-green and you've got my variant of color blindness (or color vision deficiency as my ophthalmologist would insist you call it).
Something that people occasionally notice is that all of t
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Re: flipping nerves and vision (Score:2)
I remember hearing about doctors just reconnecting many nerves in the lower back after an accident, randomly since it couldn't be known which were which, and after some physical therapy, the patient learned to walk again under the new "wiring".
I have one questions/wonder about the "filpping the vision" experiment; what about reading, was he able to read as normal, even though the text was now upside down?
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In college I learned that seeing is almost all done in the brain; the eye just sends signals that the brain decodes and turns into a picture of reality (or what passes for reality).
TetraChromacy? (Score:2)
A vanishingly small percentage of the population actually sees four colors [wikipedia.org]. To them, we're somewhat color blind as well. I wonder if this type of therapy can be used to give us 25% blindies another color to check out?
This is ALL kinds of awesome. (Score:2)
First, it's a great achievement just to get the protein appearing sustainably in the right place. More importantly, though, this provides color perception in adult animals whose brains have never received red/green differential stimuli? I never would've guessed that was possible.
It gives me hope that, when we get retinal or cortical implants that can accept more than three bands of color, our brains will actually be able to handle them. Bring on all fifty-seven colors of the rainbow!
Impossible to imagine (Score:5, Insightful)
As someone who is color-blind (severely red/green), this news just astounds me.
The basic fact is that I have no idea, no point of reference to even understand what it is I don't see. It is impossible for me to imagine what "Purple" actually is, since to me it is merely a dark blue. Not hard to imagine, like an unusual experience is, but as far as I'm concerned impossible to imagine.
Until seeing this article today, I had assumed that I would never be able to understand what most people saw. Having the possibility open up is simply mind-blowing. Imagine what kind of leap that would be for more serious conditions like actual blindness.
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My uncle and cousin are red/green color blind(severe), runs in our family. I know where you're coming from. I really hope this will becoming out to the public 'soonish'. This is a huge breakthrough.
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Gene therapy is really the only actual proper cure for genetic defects know to man. And I think in retrospect, we will see it as one of the greatest inventions ever.
I mean imagine the possibilities, if you can change any genetics in your body at will!
Sure, as always, there will be downsides, and there will be a "early alpha" phase. But what we get far surpasses anything bad! And besides: Who will try to stop every human on the planet form doing research in that area or using that knowledge? ^^
The first thin
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It's nice to see someone else that thinks the color purple is a conspiracy that all the "normal" vision carry out on us. I can't tell you how many "purple" shirts my daughter has convinced me to buy. There is no such thing as "purple" it's all a conspiracy.
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It is impossible for me to imagine what "Purple" actually is, since to me it is merely a dark blue.
Oh... be careful what you wish for. If you've lived without the color purple your entire life (and I assume you don't mean the book or movie), and suddenly it appears, who knows what effect this may have... ? Suddenly eggplants and bruises and certain over-the-top prose will connect and run together... things you've never associated before, you'll now see the hidden connections... it'll blow your mind.
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They're really purple. And yellow.
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Purple looks like artificial grape tastes. In other words, you arn't missing much ;)
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I suppose for us color-enabled people, an analogy might be trying to comprehend what it feels like to have a vagina.
Then again, for slashdot, merely what it's like to touch one :-)
Glasses for Color Blindness Correction (Score:2)
I've heard of glasses that help correct colorblindness and found the following link.
http://www.dyslexia-help.co.uk/chromagen_colour_deficiency.html
They even have stuff for dyslexia.. weird.
Whats interesting is i can partially pass the tests and I don't land into any of the categories of color blindness. If i blur my eyes i can pass the tests, although i remember it being difficult in the "real" test.
You know what they say: (Score:4, Insightful)
"Monkey see, monkey blue"
I'll admit to seeing anything ... (Score:2)
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Taking it one step further, why not give them (tomorrow's warrior) the unmutated myosin gene, thus able to be 5 to 7 times stronger kilo for kilo of muscle?
Or we could just help people with genetic problems, making the human race just a little better as a race. (hopefully)
Because they will simply break their bones when excerting their force ?
Re:We prefer to be called "Chromatically Challenge (Score:5, Interesting)
They wouldn't let me join the army because I am "color blind". No-one mentioned this to me when I was in Cadets, and it's not like the topic didn't come up. I remember one day we all lined up in front of a field:
Instructor: Right. Everyone, listen up. Today we are doing a sweep search exercise. Hidden in this field are 6 soldiers, all highly trained in the skill of camouflage. You will form a single line, one arm length seperation, and walk this field. Be attentive, they may be right in front of them and you won't see them.
[I raise my hand]
Instructor: Yes cadet, what is it?
Me: Do you mean [pointing] that guy, that guy, that guy, that guy, that guy, and that lady?
Instructor: [Sigh]. Ok smart-ass, you're dismissed. Everyone else, turn around while we reconfigure.
But hey, at least they won't draft me.
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Wait, you're color-blind, but you could distinguish more colors than other people?
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Camouflage works by dressing those trying to hide in similar colors to their surroundings. You unevolved people with your "normal" color vision are a monoculture that are easily fooled by such tricks. Us mutants have an evolutionary advantage ;)
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Wait, you're color-blind, but you could distinguish more colors than other people?
Think of it more this way, in a graphics application you could do RGB separation. If your image is vastly dominated by one color, say green, it might be a lot easier to see differences in the red/blue color spectrum if green is zeroed out. Now the eye is a bit more complicated than that but it's the same principle.
It reminds of a blind test I saw of the mp3 format - the winner who could distinguish mp3s the best had an ear injury. The result was that the tone masking mp3 uses didn't work for him because he
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I think that part of the issue is that some 'color blind' people aren't actually impaired, they just assign colors to wavebands in not quite the majority manner. For example, grass actually has more 'orange'-wavelength light in it than green, but most people see it as green, being hyper sensitive to green. If you are somewhat less sensitive to green and see it more as orange, they call you color-blind.
According to the standard color tests, I see no red, none. Yet I do have a vivid experience of red, and
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Things must have changed since the Korean war, because my dad was in the 101st airbourne and he's color blind. They wouldn't let him in the USAF though, and that's the branch he wanted to be in. Not sure if it was because he was colorblind or because he was missing part of one of his fingers.
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Sure, this is the best article on the subject I've seen:
http://critiquewall.com/2007/12/10/blindness [critiquewall.com]
Enjoy.
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I'm red color blind too.. and most of the items and clothing I own are red.. I even drive a cherry red camaro. I can see better in the dark and I have a sharp resolution.
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Better than Gene Ray, at least. Or Gene Raskin.
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I think I have an idea of what it would feel like. After being severely nearsighted and wearing coke bottle glasses all my life, I got a cataract in my left eye from some prescription steroid eyedrops and got one of the new acommodating IOLs implanted. If you don't wear glasses you can't imagine what it's like to wake up in the middle of the night and actually be able to read the clock without searching for you glasses!
I've had the implant since 2006 and I still marvel. I imagine seeing "true*" colors would