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Biotech Science

Viruses Infected By Viruses 341

SpaceAdmiral writes "Scientists have discovered a virus that can infect another virus. The fact that viruses can essentially get sick may change the debate over whether they are alive or not. Check out Nature for a slightly more technical article about the 'virophage.'"
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Viruses Infected By Viruses

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  • by Joe The Dragon ( 967727 ) on Wednesday August 06, 2008 @10:17PM (#24505651)

    We call it 3 stooges syndrome and Mr. Burns has it.

  • Re:cancer (Score:5, Insightful)

    by smittyoneeach ( 243267 ) * on Wednesday August 06, 2008 @10:17PM (#24505653) Homepage Journal
    Only a few years ago.
  • by Nymz ( 905908 ) on Wednesday August 06, 2008 @10:32PM (#24505789) Journal
    Great fleas have little fleas upon their backs to bite 'em,
    And little fleas have lesser fleas, and so ad infinitum,
    And the great fleas themselves, in turn, have greater fleas to go on,
    While these again have greater still, and greater still, and so on.

    - Augustus de Morgan [wikipedia.org], A Budget of Paradoxes

    While I haven't heard of a virus hijacking another virus, I have heard of researchers hijacking viruses to do good things. [dailygalaxy.com]
  • in school? (Score:3, Insightful)

    by commodoresloat ( 172735 ) * on Wednesday August 06, 2008 @10:35PM (#24505817)

    you must be one of those students who are learning to write viruses...

  • by maxume ( 22995 ) on Wednesday August 06, 2008 @10:39PM (#24505841)

    You should look into what shit is made out of.

  • here we go again (Score:5, Insightful)

    by Estanislao Martínez ( 203477 ) on Wednesday August 06, 2008 @10:46PM (#24505889) Homepage

    A lot of times in school, I was told viruses aren't alive because they can't reproduce. I always wondered if this would apply to eunichs or mule.

    For the debate over whether viruses are "alive" to make any sense, there has to be some literally essential difference between things that are alive and things that are not. The past 200 years or so of biology ought to have taught us that, contrary to what seemed evident to the ancients, there isn't any such essential difference. Organic matter is just a form of organization of inorganic manner. From the point of view of what the ancients knew, there was a huge gulf between everyday living beings and inert objects. From the point of view of what we know, there are many intermediate cases.

    So, instead of wasting time trying to decide whether viruses are "really" alive or not, you should just accept the fact that our knowledge today is advanced enough to show that the question--which we inherited from people who knew less than we do--is flawed.

  • by Anonymous Coward on Wednesday August 06, 2008 @10:50PM (#24505921)

    To me, the issue of how to define "life" is only a small side note to this discovery.

    Far more important are the consequences for medicine. Viruses can be attacked by other viruses. This is huge. Compared to bacteria, viruses have been very difficult to beat. Infectious bacteria can be combated by using anti-biotics, bacterio-phages and other means. Whereas viruses are significantly more hardy, and combating them directly is difficult. But this discovery opens the door to engineering virophages to attack viruses in our bodies that make us sick.

  • Re:not alive (Score:5, Insightful)

    by Telvin_3d ( 855514 ) on Wednesday August 06, 2008 @10:54PM (#24505943)

    Neither can thousands of other parasitic species. All the same no one debates the status of all sorts of fungus and ferns and others who tap directly into the circulatory system and other facilities of their host and cannot survive or replicate without them.

    If a true answer or classification as to whether viruses are alive or not comes about, I suspect it will be far more subtle and elegant.

  • by maxume ( 22995 ) on Wednesday August 06, 2008 @10:55PM (#24505951)

    There is a joke in there somewhere about you aptly demonstrating your similarity to a rock.

  • by Lost Engineer ( 459920 ) on Wednesday August 06, 2008 @10:56PM (#24505961)

    I will accept nothing less than slashdot comments to read with my fine whisky.

  • Re:reproduction (Score:5, Insightful)

    by Anonymous Coward on Wednesday August 06, 2008 @11:05PM (#24506013)

    makes it fairly easy for humans to "create life" in the form of self-reproducing machines.

    What's so easy about that? It's never been done! It would be a stupendous thing if it were.

  • Re:not alive (Score:1, Insightful)

    by Anonymous Coward on Wednesday August 06, 2008 @11:15PM (#24506095)

    Does anybody knowledgeable actually consider this "debate" interesting or important? It's a matter of semantics, surely no more interesting than the question of whether Pluto is a planet, which also got way more press attention than it was worth.

  • Re:not alive (Score:5, Insightful)

    by fm6 ( 162816 ) on Wednesday August 06, 2008 @11:16PM (#24506107) Homepage Journal

    Those parasitic species know how to do cellular reproduction. They also know how to metabolize stuff. They interact with their environment, even if that environment is another species. Virus are just reproduction machines. If RNA is the software of biology, the individual living things are the computers, and a virus is just a floppy disk that can't do anything until you stick it into the computer.

    Actually, I think the whole issue is kind of meaningless. "Alive" is a concept we invented when it seemed pretty easy to tell living things from not-living things. Like all such concepts, it tends to break down as our knowledge of the world grows, and the old definitions become hard to apply. We just went through a similar issue with the word "planet".

  • by moteyalpha ( 1228680 ) * on Wednesday August 06, 2008 @11:22PM (#24506147) Homepage Journal
    It takes time for these things to filter down to the education system because of their momentum and lag. I noticed in the early days of PC development it was almost a joke to listen to college professors talk about computer design. I recently took courses in molecular genetics and though it was good for the basics, it incorporated ideas like central dogma ( DNA - RNA ) that are also not completely true. The idea that there are self-catalyzing molecules is sufficient to define a perpetual loop. On this /. topic, ( V vs V ) it does lead into something which I have wondered about for some time, which is the chemical system underpinning of genetic life, which must surely exist in the protein world.
  • Re:reproduction (Score:5, Insightful)

    by arotenbe ( 1203922 ) on Wednesday August 06, 2008 @11:25PM (#24506161) Journal

    What about computer viruses and worms? Some people argue that those are life, especially worms which are able to reproduce in their environment independently without a host.

  • by Brian Gordon ( 987471 ) on Wednesday August 06, 2008 @11:33PM (#24506211)
    Well they probably don't make themselves sick. Is there a neverending chain of viruses making other viruses sick? I suppose a PO box could, in theory, break the chain..
  • Re:not alive (Score:2, Insightful)

    by Anonymous Coward on Wednesday August 06, 2008 @11:50PM (#24506279)

    *I* can't self-replicate, and I'm alive.

  • Re:not alive (Score:4, Insightful)

    by nospam007 ( 722110 ) on Thursday August 07, 2008 @12:29AM (#24506475)

    > No, they are not alive even if they can get sick. Viruses, even infected ones, cannot
    > self-replicate as they require the use of a host and host machinery. ...

    So cuckoos aren't alive either, since they rely on somebody else's 'machinery'?

  • Re:cancer (Score:5, Insightful)

    by LightPhoenix7 ( 1070028 ) on Thursday August 07, 2008 @12:35AM (#24506505)
    This bigger point being - while science may have come a long way, reporting of science in the media has not.
  • Re:reproduction (Score:3, Insightful)

    by sxeraverx ( 962068 ) on Thursday August 07, 2008 @12:47AM (#24506567)
    Hell, fire's 'alive' by that definition. As long as it's got fuel, it metabolizes fuel, it physically grows as time goes on, and often, one flame will split into two when the fuel in the middle runs out. Yes, I know there's more to it than that, but I'm just pointing out that we've gotta be careful about how we define life, or else we run into a few problems we aren't anticipating.
  • by Estanislao Martínez ( 203477 ) on Thursday August 07, 2008 @02:11AM (#24506887) Homepage

    It would seem to me that there is some significant qualitative difference between humans and rocks. Extending that further, it seems there exists differences between bacteria and rocks.

    Yes, there are countless differences there. But let's assume the number of logically independent differences between a bacteria and a rock is N. This means that there are 2^N - 1 logically intermediate cases between bacteria and rocks. Now we're supposed to draw a line that says that some of those cases are definitely "life," and that some are not.

    What's worse is that the exercise of drawing that line adds nothing to our knowledge.

    Essentially, the question is what is the largest subset of differences that can be used to distinguish between something that is alive and something that has never been alive.

    The problem here is simple. Your list is either going to be arbitrary, or it's going to admit of intermediate cases. (And do note that, from the point of view of modern biology, the existence of intermediate cases between paradigm examples of "living" and "nonliving" things is, if not required, at least very convenient for the theory that all uncontroversial "living" things evolved from uncontroversial "nonliving" things.)

    A question arising from the previous one is, what is it exactly that separates life from death. We can't even detect life - only the by-products of what we define as life. Thus we define death as the absence of those by-products of something that at one point had displayed those by-products.

    Again. You identify N by-products. Then some dude discovers a thing that has N-1 of those byproducts, some other dude discovers one that has N/2, and a third one discovers a thing that has (N/2)+1 of them.

    So I would disagree that the question is flawed. I think it might be oversimplified sometimes, but that at its core, it captures a very fundamental set of questions which essentially, arise from, "What does it mean to be human?" and "What is intelligence?"

    But those are cosmological questions, not empirical ones. Please spare us from your attempt to force your cosmology on us by disguising it as biology. If you wanna talk about biology, let's stick to our understanding of empirical matters.

  • Re:reproduction (Score:2, Insightful)

    by thousandinone ( 918319 ) on Thursday August 07, 2008 @02:48AM (#24507057) Journal

    All viruses are parasites that depend on a host's replicating machinery by definition, therefore cannot be considered living.

    Don't all 'higher' animals begin life essentially as a parasite within the mother? Now granted, its the same species in this scenario, but it's still something to think about.

    What about fungi? They are considered organisms and alive, yet they grow as a parasite in or on a living host or other form of organic matter, and cannot grow or reproduce without said host. That's not too far off from how a virus reproduces. True, fungal reproduction does begin within the cells of the fungus itself, but the line really isn't as clear as many would think.

    On that note, no life form truly reproduces autonomously; the chemicals that life is formed of are created/encoded from outside materials. Animals take in these outside materials by eating, plants draw them from the ground, fungi from the aforementioned host/organic matter.

    That said, It is true that when viruses replicate, the 'parent' virus does not take in material to reproduce (and rather, as mentioned, hijacks the host cells systems to do so). As important as that distinction may sound, I believe that when compared to how 'true' life forms reproduce, it seems mainly a question of semantics. It's a tough call, I guess all that can be said is that viruses certainly define the term 'gray area...'

  • Re:reproduction (Score:3, Insightful)

    by Cassius Corodes ( 1084513 ) on Thursday August 07, 2008 @03:06AM (#24507125)
    Any definition of life doesn't make everyone happy because life is subjective. Life exists on a scale where at one end we all agree its not alive, and on the other we all agree it is alive - however just drawing a line somewhere in between and saying from here on in its 'alive' is pointless.

    The same issue occurs when trying to define where one species stops and another starts in animals.
  • Re:reproduction (Score:3, Insightful)

    by bytesex ( 112972 ) on Thursday August 07, 2008 @04:11AM (#24507433) Homepage

    It's the same thing with planets and Pluto; early in school you need simple classifications. Unfortunately, some people will never really outgrow this level and continue to need them throughout their lives.

  • Re:reproduction (Score:3, Insightful)

    by Stooshie ( 993666 ) on Thursday August 07, 2008 @06:07AM (#24507811) Journal

    ... I've never heard of a computer worm that can reproduce without actually having their code executed ...

    GGGP

    ... [viruses] are essentially static objects until they bump into a cell ...

    In other words until their code(DNA) is executed. Same definition applies.

  • Re:reproduction (Score:3, Insightful)

    by x2A ( 858210 ) on Thursday August 07, 2008 @08:15AM (#24508363)

    Not if they don't believe in evolution.

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