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Biotech Science

Major Advance In Understanding Cell Reprogramming 54

Researchers at the Harvard Stem Cell Institute and Massachusetts General Hospital have taken a major step toward eventually being able to reprogram adult cells to an embryonic stem cell-like state without the use of viruses or cancer-causing genes. In a paper released online today by the journal Cell Stem Cell, Konrad Hochedlinger and colleagues report that they have both discovered how long adult cells need to be exposed to reprogramming factors before they convert to an embryonic-like state, and have "defined the sequence of events that occur during reprogramming."
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Major Advance In Understanding Cell Reprogramming

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  • This is a big deal (Score:3, Interesting)

    by PIPBoy3000 ( 619296 ) on Friday February 15, 2008 @12:45PM (#22435660)
    I read the abstract (the article is for-purchase) and it looks like they have a better feel for what it takes to turn adult cells into embryonic stems cells. Furthermore, they identified cell markers that let you better isolate these cells from other cells that haven't made the transitions between the two states.

    I think what you'll start seeing is much better efficiencies for upcoming cloning experiments (currently it's incredibly poor), as well as people starting to talk about theraputic stem cell treatments (since you can better guarantee the "purity" of the cells you're injecting into people).
  • Cell aging (Score:2, Interesting)

    by bindo ( 82607 ) on Friday February 15, 2008 @12:51PM (#22435742)
    I was under the impression that this is half the problem. Build replacements.

    The other half is rejuvenate cells and especially their DNA. Are the two separate or do embrionic cells behave differently in the handling of telomers as I understand gametes do ?

    If not this is useful to repair broken bits and pieces not to rejuvenate aging tissue.
    bindo
  • by clonan ( 64380 ) on Friday February 15, 2008 @04:06PM (#22438532)
    As a Christian, I have no problem with embryonic stem cell research either.

    The bible clearly states that the unborn are chattle and while they are human life, they aren't a human person. Virtually all references to the start of life include breath/breathing etc. You actually have to strain very hard to find biblical support for embryonic protection.

    I just personally disagree with the creation of embryo's for the sole purpose of destroying them. They may not be a person but they are still valuable.

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