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Biotech Science

DNA Vaccine May Treat Multiple Sclerosis 127

GSASoftware writes "Multiple sclerosis is a serious, as-yet incurable neurological disease which causes blindness, paralysis and other serious symptoms. In a new development, a neuroimmunology researcher in Montreal has developed a therapeutic DNA vaccine. The cause of the disease is not fully understood, but it appears to be auto-immune. If a DNA vaccine can be an effective therapy for this auto-immune disease, is it possible that DNA vaccines could treat other auto-immune diseases like Crohn's, eczema, and others?"
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DNA Vaccine May Treat Multiple Sclerosis

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  • by charleylc ( 928180 ) on Wednesday August 15, 2007 @01:51AM (#20233495)
    There's always the possibility that it *could* work for other auto-immune diseases.
    It's kind of mute point, though, to ask such a hypothetical question when the original story is about a new therapeutic DNA vaccine that only produces "beneficial changes" with "periods of remission".
    While this is a huge step forward, it is far from being introduced into the mainstream medical community for mass use. TFA states that it is in the early stages of being studied.
    Although the article does say that it's possible that it could be developed for other auto-immune diseases, I think it's a little preemptive to start asking such hypothetical questions when the target disease for which the drug is being developed isn't even out of the test stage.
  • by lordvalrole ( 886029 ) on Wednesday August 15, 2007 @02:02AM (#20233533)
    My mother has MS and I know others as well that have it. It is such a horrible disease. I hope this research continues and is a viable option and soon. Nothing is worse than seeing a parent or loved one just lose their abilities over a few years.
  • by backslashdot ( 95548 ) on Wednesday August 15, 2007 @03:25AM (#20233783)
    Multiple sclerosis is when your immune system attacks a nerve's covering called myelin. What the vaccine does is it gets the immune system to stop targetting the myelin by causing a reduction in the T-cells that attack it. If it works as they say, and have demonstrated, it only reduces the number of T-cells that target the myelin protein, not other stuff.
  • by Anonymous Coward on Wednesday August 15, 2007 @03:29AM (#20233795)
    Good grief, why don't they just get on with it and call it gene therapy. All this 'therapeutic DNA vaccine' is it because you think people will be scared by something genetic?

    ZOMG! zombie mutant viruses NO WAY!
  • Why such offense? (Score:3, Insightful)

    by Slashdot Parent ( 995749 ) on Wednesday August 15, 2007 @01:29PM (#20238783)
    I'm unclear as to why you took so much offense to the GP's attempted humor.

    His joke itself, of course, was not funny. It's a play on the wording of the title. Instead of parsing it as a DNA vaccine against MS, he parsed "DNA Vaccine" as a vaccine against DNA. The attempted humor being, if you don't want to be "infected" with DNA, use a condom.

    You somehow interpreted his joke to imply that MS was caused by unprotected sex. I didn't read the post that way, and anyhow, I have never heard anyone suggest, either credibly or in jest, that MS is an STD.

    In fact, I found the "joke" to only be making fun of the article's title, and not MS itself. As hard as I try, and as many angles as I search, I am unable to come up with any situation in which MS could be humorous.

    Wife diagnosed in '05.

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