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Biotech Science

Skin Cells Turned Embryonic 261

anik315 writes "Nature is reporting a major breakthrough in embryonic stem cell research. A straightforward procedure using mouse fibroblasts harvested from the skin can be used to produce pluripotent stem cells that can potentially become any other cell in the body. Not only can Yamanaka's method use the most basic cells, it can be accomplished with simple lab techniques. Possible applications of this breakthrough are to check molecular changes in cells as certain conditions develop. Stem cells produced using this procedure, however, can not be used safely to make genetically matched cells for transplant."
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Skin Cells Turned Embryonic

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  • Re:I knew it.. (Score:4, Insightful)

    by CaptainPatent ( 1087643 ) on Wednesday June 06, 2007 @06:26PM (#19417555) Journal
    Actually it is. We have already been using skin grafts to cure minor cosmetic flaws from burns or scars with no moral repercussions. I don't see why it would suddenly become immoral to expand that to much more life-threatening diseases and ailments.
  • by Anonymous Coward on Wednesday June 06, 2007 @06:41PM (#19417685)

    The summary seems to suggest that the DNA isn't made well enough even to make perfect transplants for the person donating the skin.

    At present, they use retroviruses to get the four factors that cause the transformation into the cells. The retroviruses mess up the DNA. There may be other methods though besides retroviruses to get the factors into the cells.

    Of course, the factors themselves may also increase the risk that the cells become cancerous - which could turn out to be a harder problem, or not, it's hard to say at this point.

  • Re:I knew it.. (Score:5, Insightful)

    by buswolley ( 591500 ) on Wednesday June 06, 2007 @06:46PM (#19417725) Journal
    Seriously, this is not a scientific question, but a moral/ philosophical question. There IS room for debate. However, as a promising source of embryonic stem cells, this discovery may reduce the importance of the debate. I think that the abortion debate in general should be solved in this way. Make the debate less important by solving the problem of unwanted pregnancies directly with good birth control.
  • Re:I knew it.. (Score:3, Insightful)

    by eln ( 21727 ) on Wednesday June 06, 2007 @06:53PM (#19417793)
    Sure, but the same people who are the biggest advocates against abortion also tend to be the ones that seek to limit access to birth control, so that argument doesn't get very far either.
  • by TheMeuge ( 645043 ) on Wednesday June 06, 2007 @07:11PM (#19417989)
    <blockquote>what is the justification for using public money for research that tens of millions of people consider murder</blockquote>
    Frankly, I think we should do it just out of spite... for people who would spout the kind of self-important ignorant garbage that just evacuated itself from the barren environment of your skull.
  • by sumdumass ( 711423 ) on Wednesday June 06, 2007 @07:12PM (#19417997) Journal
    Heh, those anti abortion people aren't as stupid as they are portrayed. And this is something that always confused me. Why someone who thinks they are protecting a human life automatically be considered stupid in this one position?
  • by twitter ( 104583 ) on Wednesday June 06, 2007 @07:17PM (#19418039) Homepage Journal

    the same people who are the biggest advocates against abortion also tend to be the ones that seek to limit access to birth control, so that argument doesn't get very far either.

    Sure it does, if reasonable people can ignore the others. The problem is unwanted pregnancy and reasonable people can work together to reduce it and support the people who have the problem. The use of obnoxious and confused advocates is an underhanded way to kill off a proposal.

    The counterexamples are communists, extreme feminists and corporate monsters who put production above personal well being. They don't value babies because they don't value each other.

    You don't have to be religious or hate sex to think that abortion is murder. In almost all cases, if no one does anything to a pregnant woman, a child will be born. The person who stops that birth has ended a human life. It is a terrible thing to do and it is not justified by other terrible things, lack of resources or potential uses for the remains.

  • Re:I knew it.. (Score:2, Insightful)

    by tukkayoot ( 528280 ) on Wednesday June 06, 2007 @07:21PM (#19418079) Homepage
    Of course, I was just being facetious -- parodying the extreme and ludicrous characterization of embryonic stem cell research/therapy as involving "dead babies." Except that my description of the procedure is actually technically accurate (at least so far as I can tell, if it went beyond the animal testing stage). Of course, if you have to explain the joke, you've already failed as comedian. I apologize for my inept attempt at humor. :)

    I have no problem with this technology or research, but then I also think there is no ethical dilemma with the use of embryonic stem cells for medical purposes/research either. I think it's ridiculous to say we have a moral obligation to a tiny clump of cells with no nervous system ... about the only way that you can raise such concerns is to assume some sort of empirically unsupported vitalist superstition.
  • hardly a troll (Score:3, Insightful)

    by feepcreature ( 623518 ) on Wednesday June 06, 2007 @07:24PM (#19418113) Homepage

    The poster makes a serious ethical point.

    However emotively he put it, surely it's quite different to take tissue from a consenting human donor than from a subject whose life has just been ended - however "potential" its (his? her?) humanity may be.

    Don't all but the most extreme "it's the woman's body till it's born" zealots regard the abortion of a foetus (with its potential to grow into a human adult) as a necessary evil, rather than a simple lifestyle choice?

  • by david.given ( 6740 ) <dg@cowlark.com> on Wednesday June 06, 2007 @07:46PM (#19418315) Homepage Journal

    For example, let's develop several pre-conception birth control methods which are highly effective. Then require their use in-order to have the privilege of having an abortion. --Like insurance for your car. Responsibility allows the privilege.

    The problem with this approach is that you're punishing the children. You're rewarding being responsible by allowing responsible people to have children, and punishing the being irresponsible by forcing them to go through with their pregnancies --- in other words, you're selecting for children to be born to those people least suited for raising children.

    This is not optimum.

  • by raehl ( 609729 ) <raehl311@@@yahoo...com> on Wednesday June 06, 2007 @08:07PM (#19418453) Homepage
    Besides, a moderate approach would be to acknowledge that the issue is unclear, or unsolvable

    That would be a moderate approach.

    an ... approach would be to acknowledge that the issue is unclear, or unsolvable, and that it is probably best to error on the side of caution.

    This is not a moderate approach. If caution is 'towards killing babies', this is a pro-life approach. If caution is 'towards government invasion of a woman's control of her own body', then it's a pro-choice approach.

    Either way, it's the same as saying "We can't agree, so we should assume I'm right in the meantime."

    When you get down to it, aborting pregnancies is in general not desirable behavior. But, the government trying to force women to carry pregnancies to term is not desirable either, with various degrees of not desirable based on circumstance. (Forcing a rape victim to carry a pregnancy to term is probably less desirable than forcing a healthy 30-year old with a healthy pregnancy to carry that pregnancy to term.)

    The problem is, while all of that is undesirable, which is MOST undesirable is not a statement of fact. No one has been able to put forth some sort of scientific basis for determining whether the hypothesis 'Government restriction of a woman's ability to have an abortion is preferable to terminating pregnancies' is true or not. So whether a given person believes that to be true or not is based solely on their own personal evaluation of which of their values is more important.

    So what's better, letting a group of the population use the government to choose for everyone how their pregnancy should be handled, or letting each woman choose what to do about her own pregnancy?
  • by bogjobber ( 880402 ) on Wednesday June 06, 2007 @08:35PM (#19418701)

    5. Creates a registry of not only who's having sex, but who is using birth control. No privacy concerns there.

    6. Still requires the Supreme Court to overturn Roe v. Wade.

    Sorry, try again. I, for one, would certainly not consider your proposal moderate. Drastically reducing the amount of freedom women have right now in order to placate a relatively small percentage of the population does not strike me as moderate. "A Modest Proposal" maybe, but definitely not moderate.

  • Re:hardly a troll (Score:3, Insightful)

    by rrohbeck ( 944847 ) on Wednesday June 06, 2007 @08:45PM (#19418795)
    >Don't all but the most extreme "it's the woman's body till it's born" zealots regard the abortion of a foetus (with its potential to grow into a human adult) as a necessary evil, rather than a simple lifestyle choice?

    Yup.

    But remember that it's only a fetus after a couple of weeks. Before that, it's an embryo. Bare naming issues aside, you have to draw a line somewhere between a couple of cells and a human being.
    Getting rid of a couple of cells is only a big issue if the morality aspects get blown way out of proportions by religious zealots. No, it's not a human being.

  • Re:I knew it.. (Score:3, Insightful)

    by mrbooze ( 49713 ) on Wednesday June 06, 2007 @08:46PM (#19418801)
    Why is the abortion debate involved in this at all? Stem cells used in research are not acquired from abortions! Abortions are a terrible source of stem cells for research purposes.
  • Re:I knew it.. (Score:1, Insightful)

    by Anonymous Coward on Wednesday June 06, 2007 @08:58PM (#19418929)
    Your first post had the beginnings of an argument (albeit, one I disagree with). You were moderated down because you went off into unnecessary personal attacks. Your second post was moderated down because you did the same.
  • Re:I knew it.. (Score:3, Insightful)

    by xaositects ( 786749 ) * <xaos.xaositects@com> on Wednesday June 06, 2007 @09:26PM (#19419127) Homepage
    the most vocal, and therefore the most influential anti-choice proponents claim that birth control for women is tantamount to abortion as most prevent the egg from adhering to the wall of the uterus, or prevent it from traveling down the fallopian tubes, where it can grow further. Condoms, therefore, can be the only one they can support, but those same supporters tend to be the ones who want to preach abstinence because their head seems firmly implanted in the sand, doomed to pretend people from kids to grandparents do not have sex or sexual urges (This mindset seems to be the biggest barriers against sexual education in youth.)

    This is why the argument does not go far. The only ones who speak loudly enough to argue, tend to be the very evangelical of the crowd. That comes from firsthand experience at protests. Those very vocal people are quick to judge. Even at clinics where women who have gone through a non-induced miscarriage that was no fault of their own go to seek treatment afterwards, pro-life people stand and hurl insults at them, not knowing even a part of the story.

    I support embryonic stem cell research, as I have Type 1 diabetes and stand to gain from this research. Most of the eggs used were discarded and would never have come to fruition as a human anyway.
  • by EMeta ( 860558 ) on Wednesday June 06, 2007 @09:47PM (#19419275)
    Without mod points, I must resort to replying to a highly ranked troll. Sigh.

    First, if you would RTFS, much less article, much less paper, you would know that one of the fascinating things about this procedure is that it uses skin cells, not embryonic cells as a base. Very few people who believe in any invasive medicine have a problem with this. This is a breakthrough in part because it fixes problems like embryonic harvesting or even The Island-esqe people harvesting because a given sick person could use it on him or herself.

    Secondly, a work force that lives productively into their 80's would be a lovely thing for any society's economies. A government should certainly be concerned about its nation's economy, yes?

    Thirdly, medical research=good for people. Democratic government=group that uses pooled funds for betterness of group. Are there spending issues? Duh. But still better than most systems. I want to put my money in a pool that can fund science. Hooray that there is an automatic way that this happens for me. I don't even need said science to produce economic results for me to be happy about it. But if it's going to, I won't turn that down.

    And for the record, a considerable majority of Americans do want stem cell research, even from embryos. Google news reports around last Nov's Missouri senate elections, & there were several stories about how while most Americans support it, it's a non-issue in the polls.

  • by sumdumass ( 711423 ) on Thursday June 07, 2007 @12:06AM (#19420189) Journal
    There are some deep problems with this proposal. First is that it attempts to vacate the idea that the fetus is an unborn child and acts as if it is a living human intruder. Next, it attempts to treat the body as property in the same way land or a house would be considered property. But it doesn't treat the intent and condition in a relative term. It may be because someone is attempting to justify the action or it maybe because they think a strawman argument rearranged makes more sense.

    To keep it in the same terms, lets put it into perspective to keep the comparison real.

    A woman has the perfect right to evict any intruder from her property, that is, her own body, at any time, for any reason. (Self-ownership is the first principle of liberty.)
    But she doesn't have right to kill the trespasser without giving them enough time to leave. In almost any state, with the exception of Texas maybe, if you find a trespasser/intruder and they pose no direct harm to you or anyone there, you tell them to leave and then kill them because they didn't leave fast enough, you will be going to jail. But pregnancy isn't even a trespasser or intruder, it is a welcomed guest. You have to take certain actions to invite a fetus into your home(body). And in every state, if you invite someone into your house and then kill them, it is murder.

    I know this is someone else's rationalizing. But we can often make judgments to justify something that other see as wacked. You cannot run over a kid playing ball in the street because thats where cars drive when you have plenty of time to stop. Saying the kid shouldn't be playing in the road is just an attempt to justify it to yourself but doesn't make it just. Leaving out the fact that the intruder is crippled and will take a certain amount of time to leave the property and killing them before they can do so because you ordered them out makes no sense either. And repeating this nonsense make even less sense.
  • by Grendel Drago ( 41496 ) on Thursday June 07, 2007 @09:50AM (#19422829) Homepage

    Don't make the mistake of grouping all pro lifers all into the same group. This is probably the biggest reason your confused about who would support something or why they are supporting it.
    Yeah, but pro-lifers not in the religious group don't really count in a political sense, which means that whatever your nuanced policy measures are which aren't predicated on punishing women for being dirty sluts, nobody's going to bother responding to them.

    Then again, your wailing about "encourag[ing] promiscuity" and how those damned sluts deserve to be punished with unwanted pregnancies because, well, they were asking for it, what with the having sex and all, leads me to believe that your motives may not be that different.

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