Researchers Use 'Decoy' Molecule to Treat Cancer 40
Jerry Rivers writes "The Globe and Mail is reporting that scientists in British Columbia have successfully used a 'decoy' molecule to shrink advanced prostate tumors. Citing a paper published in the Proceedings of the National Academy of Sciences, the the Globe story explains how the researchers are the first to find a way to block the process of androgen reception in cells and prevent, a key trigger in the onset of prostate cancer."
Article (Score:5, Informative)
http://www.pnas.org/cgi/content/abstract/104/4/13
Re:Only problem is.. (Score:3, Informative)
All too true, litigation after (sometimes perceived) errors by scientists and drug companies has caused reluctance to make new medicines rapidly available.
But in cases of terminal illness such reluctance has more than once been overruled as a potentially failed treatment is never worse than the alternative.
From TFA:
"I don't think we're years and years away from it," she said of the creation of a drug. "Now that the paper has just come out there will certainly be pharmaceutical companies that will be jumping on this. I believe this is a paper, or work, that will cascade, to have very rapid screening against this therapeutic target," she said.
Re:Soon, soon, soon.... (Score:1, Informative)
A little more info (Score:5, Informative)
They managed to test against human tumors which had been xenografted into mice, they packaged their new therapeutic transgene into a modified lentivirus then injected the virus directly into the tumor site.
While this result is promising, it suffers from the same drawbacks as many gene therapies: we can figure out what to put into the cell to fix it, but the big problem is finding a very effective vehicle (virus) to target a high proportion of the required cells.