Deep Brain Stimulation as Depression Treatment 273
Neopallium writes "Medtronic, today announced its intentions to pursue a major clinical trial of the company's deep brain stimulation (DBS) technology in the treatment of severe and intractable depression, a disabling form of the psychiatric disorder affecting millions of people worldwide. "While not a cure, DBS has allowed these patients to return to much more functional and happy lives," said Dr. Rezai, who represented an international working group of physicians that has been studying the application of DBS therapy in the treatment of intractable depression and OCD in collaboration with Medtronic."
Re:Stimulating (Score:1, Interesting)
Interestingly, the caffeine dose equivalent to about 5 (five) cups of coffee per day has been shown to be effective in preventing Parkinson's.
Re:Unexpected side-effects (Score:3, Interesting)
As someone with bipolar disorder, I welcome any further additions to the repertoire of weapons we have against serious depression. I just hope no one in the trials commits suicide, a common occurrance of people who are just beginning to have their depression lifted.
Obligatory Dilbert Quote (Score:2, Interesting)
"You're just allowed to
Great, now what is it? (Score:2, Interesting)
The Original Clockwork Orange (Score:5, Interesting)
I managed to get a copy of the book finally, and discovered wonderful passages such as the following on page 115:
This passage is eerily reminiscent of a passage from Richard Dawkins' "The Extended Phenotype [amazon.com]" chapter titled "Host Phenotypes of Parasite Genes":
Quirks and Quarks (Score:1, Interesting)
Placebo (Score:2, Interesting)
There are obviously people around who do not respond to any kind of treatment, and I sincerely hope that this new treatment can help them find some relief.
Primal Therapy is a cure for depression. (Score:2, Interesting)
It's possible to read the book [amazon.com] and do what it says. But that is very scary and only someone with a strong sense of logic is able to guide himself or herself.
Thank fucking God... if it works. (Score:3, Interesting)
Most anti-depressants have really, really bad side affects; prozac is by far the best, but it seems to muffle several higher brain functions... not completely silenjce, but more than enough to be noticeable and very frustrating. Zoloft is the fucking devil and is extremely habit forming, not to mention that it destroys your liver and your immune system. Trying to quit Zoloft cold turkey is like trying to do the same with hard drugs, many people become very, very sick and suffer bowel and stomach problems for days. Zoloft can also cause those feelings in people for the entire duration of their medication; I was one of those people. I couldn't get up in the morning when taking Zoloft and not throw up at least once, and feel like I'd contracted anemia for the whole day. One of my dearest friends was medicated with Zoloft (at twice my dosage, which is ridiculous) for OCD and depression; needless to say, her liver has been annihilated. Even after a year of having stopped taking Zoloft, she maintains an acute weakness to food poisoning and alcohol, which was not present beforehand. Watching her try and quit Zoloft was like watching a train wreck. I've heard similar things with other forms of depression medication, but Prozac and Zoloft are the only ones I've been medicated with, and rather heavily.
Spin Doctors? (Score:2, Interesting)
This was touted as a miracle cure for many psyciatric ailments.
Ice baths.
Frontal lobotomy.
Electric shock through the brain.
Psychiatric drugs.
Now a pager with a shock prod installed in the brain.
Isn't this the kind of stuff Evil Scientists(tm) do to their victims?
Re:There are a few loose ends.... (Score:3, Interesting)
It certainly helps when you have someone around who understands why you feel the way you do at times. Although, the reverse is also true if you both forget to take your meds at the same time.... hehe, nasty.
Anyways, she has just given birth to our first child together (its a girl).
Hopefully, she wont suffer the same problems as her parents, but if she does... well hopefully we have the understanding to help her overcome some of the issues, or at least support her during the harder times.
Re:Unexpected side-effects (Score:3, Interesting)
These kind or treatments are not usually designed for curing oddities or eccentric behaviour. Well, not at least at the present time and civilized societies. Not so long time ago things were different. Anyway, these treatments are for helping people with depression, which cannot be handled with therapy or medication. ECT is another choice, and while it seems to be effective (and it actually is, if done properly and using enough medical background studies) but we do need more subtle and more accurate methods for helping these cases.
Funny that you say "as long as they are not hurting others", well, hopefully these kind of studies are able to save depressed people who are trying to hurt themselves. For my opinion, suicide is not a proper treatment for severe depression.
Anyway, I can see your point, but I think that no one is trying to create any kind of sunny smily-face happy-happy-joy-joy society. There certainly is a model that is strived towards, but it is used for these seriously depressed people that cannot function properly. And this is only because there has to be some sort of measurement for "normal" so we can tell, when the treatment is going to the right direction (unfortunately, some times patient his/herself cannot be a reliable source for this kind of information).
let *them* decide on treatment (Score:3, Interesting)
Re:Unexpected side-effects (Score:3, Interesting)
Gee, that's really constructive ...
Your brain is strongly influenced by the chemical and hormonal bath it sits in. Its also influenced by all the sensory input it gets. The GP poster was pointing this out ... you, on the other hand, could probably benefit from a bout of severe depression - maybe it would give you some empathy for other people.