Researchers Identify Gene Involved in Regeneration 134
v1x writes "Researchers at the University of Utah School of Medicine have discovered that when a gene called smedwi-2 is silenced in the adult stem cells of planarians, the quarter-inch long worm is unable to carry out a biological process that has mystified scientists for centuries, regeneration."
Re:I for one... (Score:5, Informative)
Now, just think of the implications of this research if we can somehow learn how this gene is regulated - no more amputations, no more diabetes type 1, no more any disease where a lost body part is gone forever!
Amazing, isn't it? I love to dream, but the reality may not turn out to be that ideal...but surely something amazing is going to result from these efforts by the Utah scientists.
Re:Logic 101 (Score:5, Informative)
The thing to keep in mind for lay readers is that adding this gene to people won't automatically turn them into regenerating superheroes. However, indications are that understanding how this gene functions will tell us something useful about the mechanism by which stem cells are involved in regeneration, and that may have medical applications.
Re:Unfortunately (Score:3, Informative)
Re:More intelligent animals (Score:5, Informative)
Re:More intelligent animals (Score:5, Informative)
Specifically, the maze used to train the worms were not cleaned and chemical trails were left allowing faster training of untrained worms.
http://en.wikipedia.org/wiki/Memory_RNA [wikipedia.org]
Re:Unfortunately (Score:5, Informative)
* It can activate DNA repair proteins when it recognizes damaged DNA.
* It can also hold the cell cycle at the G1/S regulation point on DNA damage recognition.
* It can initiate apoptosis, the programmed cell death, if the DNA damage proves to be irrepairable.
Basically, cancer is uncontrolled production of cells with damaged DNA with no means of stoping it or killing it off. Regeneration, if they could pull it off, would hopefully produce cells with non-damaged or non-mutated DNA.