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Science

Bacteria-killing Pencil 285

kahrytan writes "Mounir Laroussi, a researcher at Old Dominion University has invented a hand-held device that is dubbed a plasma pencil. The pencil generates a "cold plasma," which can be used to kill germs that contaminate surfaces, infect wounds and rot your teeth. In the future, it might be used to destroy tumors without damaging surrounding tissue. When he turns the pencil on, it blows a high pitched whistle as a glowing, blue-violet beam about 2 inches long instantly appears at one end. Stick your finger in its path and you only feel a cool breeze, but the beam is powerful enough to blast apart bacteria that's crawling on your skin. Such a device if patented, tested and mass produced could end up doing a lot of good. Disinfecting surgery tools, keeping open wounds open in hospitals, destroying tumors in hard to operate areas like brains, and even treating that simple paper cut. The story can be read at dailypress and old dominion university."
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Bacteria-killing Pencil

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  • Patented? (Score:5, Insightful)

    by RAMMS+EIN ( 578166 ) on Saturday October 15, 2005 @09:55AM (#13796956) Homepage Journal
    ``Such a device if patented, tested and mass produced could end up doing allot of good.''

    Even if not patented, it could do a lot of good. Possibly even more.
  • patented? (Score:1, Insightful)

    by jmv ( 93421 ) on Saturday October 15, 2005 @09:56AM (#13796959) Homepage
    Such a device if patented, tested and mass produced could end up doing a lot of good.

    Does that mean if not patented it's not going to do any good?
  • by cinnamon colbert ( 732724 ) on Saturday October 15, 2005 @10:15AM (#13797045) Journal
    basically, this device produces a bleach like gas that chemically inactivates surfaces; it inactivates the outer layer of your skin just as much as the bacteria, but since the outer layer is dead skin cells it does not matter

    fta, it produces highly reactive oxygen spiecies.

    If such chemicals, such as peroxy radical, superoxide, etc are in fact produced, then to the extent that they get past your outer skin and react with live cells, the chemicals will produce cancerous and mutagenic lesions. If the chemcals get to the layer of living cells which is continously gowing and dividing to produce new skin, you would have to worry about skin cancers......

    Cold plasmas are of great use in modifiying surfaces, eg this pen might be perfact for grafitti removal, activating plastic so paint will stick (the activation of polyolefins like polypropylene is a big business) ...lots of other uses

    what has held back the cold plasma industry is the lack of cheap devices to play with; i have had to pay hundreds of dollars to have small (mouse sized) objects treated for a few minutes
  • natural selection (Score:5, Insightful)

    by handy_vandal ( 606174 ) on Saturday October 15, 2005 @10:17AM (#13797054) Homepage Journal
    ... the beam is powerful enough to blast apart bacteria that's crawling on your skin.

    Good news if it blasts 100% of the bacteria, 100% of the time.

    Potentially bad news if it only blasts 99.999999% of the bacteria, thus selecting for super-tough microbes.

    -kgj
  • Bioterror Agents (Score:5, Insightful)

    by MidoriKid ( 473433 ) on Saturday October 15, 2005 @10:20AM (#13797075)
    The article claims it can be used to "mop up bioterror agents". Is anyone else sick of how every new invention is measured by it's usefulness to fight terrorism?
  • by Hogwash McFly ( 678207 ) on Saturday October 15, 2005 @10:21AM (#13797076)
    While it's easy to focus on the positives, what would be the long term ramifications for such a device? The end of the summary mentions using this 'pencil' on a paper cut, which I find rather disturbing. Seriously, it seems as if bacteria (or, more rhetorically, GERMS) are replacing paedophiles in terms of evoking hysteria for protecting THE CHILDREN (OMG). If you watch any soap or bleach advert on TV, they tend to anthropomorphise bacteria as gruff-voiced killers that will strike your toddler in his highchair the minute your back is turned. The companies also make enthusiastic claims that they KILL ALL KNOWN GERMS DEAD. FOREVER. TO DEATH. KILLED. How 'killing something dead' is not at all redundant, I do not know.

    Our immune system is like a muscle, it needs to be worked to improve its strength. And, like a muscle, it can cope fine with reasonably sized loads. This doesn't mean you should go round feasting on raw burgers, but more importantly it does mean that it's not a big deal if your child (God forbid) plays outside, scrapes their knee or rolls in the mud. Actually, by keeping them inside your sanitised bubble you put them more at risk of developing asthma and other allergies, as studies have shown. In the same way that morons can't realise we got on OK without mobile phones at the movie theatre, we also got on OK without Carex Bacteria Assassination soap. Doctors prescribing all sorts of drugs to shut up hypochondriacs just exacerbates the problem further.

    Slashdotters, do your duty and eat those nose pickings!
  • by G4from128k ( 686170 ) on Saturday October 15, 2005 @10:23AM (#13797087)
    A device such as this will require clinical testing to prove that it is both safe and effective. Those tests will take on the order of 2 to 5 years and cost on the order of $25 to $200 million for each proposed use.

    Who is going to spend that kind of money if the minute they get approval, some other company can sell these devices without the clinical testing costs? The company that performed the tests will need to add $25 to $200 to the price of the device (in addition to manufacturing costs), assuming they sell a million of them. And the competitor will be able to undercut the first company on price.

    The math is even worse on a risk-adjusted basis because so many promising products fail during testing. Thus, the costs of developing several failed devices must be paid for by each successful device.

    Until governments foot the bill for all medical R&D and clinical testing, patents are a crucial part of the medical device & pharma industry.

    The point is that without a patent, nobody will pay for testing, the device will sit on a shelf, and it will do no one any good. This is why pharma and medical devices will never be like OSS -- the invention of the first instance is an extremely minor part of the cost of development. Building a better medical mousetrap is nothing. Proving it is safe and effective and gaining govt approval is everything.

  • by RAMMS+EIN ( 578166 ) on Saturday October 15, 2005 @10:47AM (#13797186) Homepage Journal
    ``The article claims it can be used to "mop up bioterror agents". Is anyone else sick of how every new invention is measured by it's usefulness to fight terrorism?''

    Yes, and I have been sick of it from almost the moment it started. People, 9/11 was shocking, but it was just _one_ event! People in other places are confronted with terrorism all the time, and most are a lot cooler about it. And why wouldn't they? It's not like you can ever make security tight enough that no terrorist could get through; the only thing it is sure to accomplish is inconvenience and deterioration of civil liberties for everyone else. All to protect you from something that is less likely to kill you than your diet, the traffic, or suicide.

    My advice? See terrorism for what it is; a minor threat to your safety brought about by fanatic maniacs who are angry about some (imagined or real) wrong your country has done to them. Get on with your lives, and don't let anybody (terrorist or politician) scare you into believing you need to sacrifice anything for your safety.
  • by Anonymous Coward on Saturday October 15, 2005 @11:04AM (#13797256)
    Actually it has the same exact problem. Antibiotics are things that kill germs, but don't kill human cells. Similarly this cold plasma kills germs, but doesn't harm people. That means it isn't very strong. There are bound to be germs that survive and those germs will live on to form strains more resistant to cold pasma.
  • How it Works: (Score:2, Insightful)

    by TadZimas ( 921646 ) on Saturday October 15, 2005 @11:07AM (#13797266)
    I'm not a bio major or anything (yet) but here's how I assume it works: The stream of 'cold plasma' is just energized oxygen and helium, packing extra electrons. When it comes into contact with a bacteria, it oxidizes the bacterias cell wall, causing them to lyse. Bam, no more bacteria. There isn't any real danger of the bacteria evolving an immunity, as we've been throwing similar tactics at them for a long time, and you probably have some in your home: Hydrogen Peroxide functions on basically the same principals.

    As for the cancer element, I'm a little skeptical. It could be used to take out cancers, but you would need to cut the patient open, locate the cancer, and spray the tumor with magic cold plasma for a couple minutes, and then you get a dead and rotting tumor inside the patient's body. It's better just to remove the damn thing. For more information: http://en.wikipedia.org/wiki/Hydrogen_peroxide [wikipedia.org] and http://en.wikipedia.org/wiki/Oxidizer [wikipedia.org]
  • by twitter ( 104583 ) on Saturday October 15, 2005 @11:16AM (#13797308) Homepage Journal
    A device such as this will require clinical testing to prove that it is both safe and effective. Those tests will take on the order of 2 to 5 years and cost on the order of $25 to $200 million for each proposed use. ... The point is that without a patent, nobody will pay for testing, the device will sit on a shelf,

    I doubt this will sit on the shelf long. A big dumb company might spend that much money testing out something that costs far more than this does. A cheap gadget like this will quickly be tested in every conceivable way by hungry graduate students at every University in existence like TLDs were. The results should start pouring out soon unless some jackass gets a pattent and demands fees which eliminate any price advantage the device has over mercury vapor lamps. In that case, we will have to wait another seventeen years and then some.

    Until governments foot the bill for all medical R&D and clinical testing, patents are a crucial part of the medical device & pharma industry.

    There's enough red tape as it is. Please don't make me go Federal for everything. Let them compile, analyze and publish statistics other people generate. Laws protecting patient privacy are fine. Making every institution apply for a Federal Grant just to buy a $50 device would be really stupid.

    There may indeed be some non-obvious and inventive tricks in this device that deserve a patent. If so, we can hope the inventor licenses things out at a price that will insure widespread adoption and great riches for himself. If not, we can only hope that they don't get any patent and everyone can start testing.

  • by HAMgeek ( 908543 ) on Saturday October 15, 2005 @11:21AM (#13797331) Homepage
    > Until governments foot the bill for all medical R&D and clinical testing... Governments do not have money to foot the bill for anything. God, I really wish people everywhere would realize that ALL governments operate with TAXPAYER money. In the U.S., if you ask people around you how much they paid in taxes last year the majority will say something along the lines of "I didn't pay anything, they payed me X dollars." Everyone everywhere should get the mindset that every single dollar, pound, yen, or whatever monetary unit they use, spent by thier government is their money. Just in the cleanup and recovery from this years hurricane Katrina and Rita billions of MY FAVORITE DOLLARS have been utterly wasted. Just in Alabama, FEMA has paid millions to move unoccupied travel trailers around, and put them into $19 a day trailer spots at various state parks where they remain unoccupied. Why unoccupied? Maily because most of the people who need them didn't come to Alabama and because only a small percentage of travel trailer parking spots in Alabama state parks have sewer hookups. Most travel trailers have gray and black water storage tanks on board and they empty those at designated terminals at the various interstate rest stops. FEMA will not let anyone occupy one of thier trailers unless the parking spot is equipped with it's own sewer tap. So they pay millions to park unoccupied trailers in the state parks, instead of parking them in the many large unused parking lots that abound around the state where large stores, such as Winn Dixie, have closed, and tow them around from place to place. That's one example of MY F'ING MONEY going to waste. Can you tell I'm p'd? I don't mind the government using tax money to help with such disasters. I don't even mind, much, when that money is used overseas because such aid to other nations is one way of making friends and alies in the region. However, USE IT WISELY. Stepping off my soapbox... I went into that little tirade to say this: It's the "it's the governments money" attitude that leads to such egregious waste and overspending being tolerated. If the people would just shed that attitude things would be much better, not only ih the U.S. but everywhere.
  • by idlake ( 850372 ) on Saturday October 15, 2005 @11:24AM (#13797345)
    Until governments foot the bill for all medical R&D and clinical testing, patents are a crucial part of the medical device & pharma industry.

    Governments (i.e., tax payers) effectively already foot the bill for a lot of drug and medical device development, even development that leads to proprietary, patented, commercial products. Furthermore, since the monopoly prices that result from patents end up being paid by government-supported health-care plans, they end up paying the rest of it, too, many times over.

    In addition, the market is doing a piss poor job in creating incentives for companies to create the drugs that people actually need; companies have an incentive to create useless variations on medicines that treat symptoms of common diseases but don't cure them. What we actually need are medicines for currently untreatable diseases and medicines that cure.

    Finally, a lot of the costly approval process is only in place because of the commercial development model; for many reasons, private companies are prone to bringing dangerous drugs to market without close government supervision. For drugs and devices developed with public funds, the approval process can be greatly simplified.

    Overall, it would almost certainly be more cost effective for everybody to abolish drug and medical device patents altogether, have government and scientists set the goals for what to develop, and have all research, development, and testing of such devices paid for by the tax payer. Private companies can still get involved through contract work and work-for-hire.
  • by vertinox ( 846076 ) on Saturday October 15, 2005 @01:35PM (#13797948)
    Governments do not have money to foot the bill for anything. God, I really wish people everywhere would realize that ALL governments operate with TAXPAYER money.

    Actually, government doesn't run on tax dollars alone, but rather Government debt.

    From http://en.wikipedia.org/wiki/U.S._government_debt [wikipedia.org]
    As of August 2005, the total government debt is approximately $7.9 trillion, i.e. $7,900,000,000,000 ($7.9 × 1012). This is more than ten times the amount of United States currency in circulation as of 2005, estimated to be $730 billion ($7.3 × 1011). The debt can also be measured as a fraction of the nation's gross domestic product (GDP); at present, U.S. public debt is about 65% of the GDP, a rather average level when compared to other nations.

    So the national debt is larger than all US dollars in circulation? It really doesn't add up. In theory this money doesn't exist and doesn't matter what you do with taxes because people think that somehow the money they pay to the government has some type of application but it really just goes into a gaping black hole.

    The whole reason the US government doesn't collapse is because the system props itself up through some strange levies of government loans and other Federal Reserve schemes. Seeing they can't just print money (like they did in Germany during the Weimar Republic which lead to 1000% inflation of the DeustchMark dollar) to pay for government things, they just have to owe a great deal of money. Since people expect the US government to be here in 200 years (and it does have some of the largest militaries and government system on the planet to backitself up) people just tend to accept the debt will be paid off eventually or at least they will make a profit on the internet in 10 years.

    I sort of snicker every time they argue about raising taxes to pay for this or that or decreasing funding for a certain project because in reality they'll end up selling more government bonds to China or Japan.

    So yes the government could very well pay for anything like funding for this pen if it wants without raising taxes or using your tax dollars. Don't get me wrong, if they were to do away with taxes all together then the national debt would spiral out of control and it is unlikley there would be enough buyers of government debt to keep up with the costs... Heck... We might be heading in that direction now if China doesn't keep buying our debt like they are now.
  • by Anonymous Coward on Saturday October 15, 2005 @01:45PM (#13798004)

    People who are crazy with medications are like that too. I know someone who is on a half-dozen prescriptions for everything from allergies to arthritis to cholesterol, and they are the sickest person I know. They always have infections, sinus problems, headaches, etc. They went into surgery recently for their sinuses and the bleeding wouldn't stop. The doctor finally figured the arthritis medication was screwing everything up and the bleeding stopped after a couple days drug-free. Pretty amazing, IMO.

  • by Bastard of Subhumani ( 827601 ) on Saturday October 15, 2005 @04:10PM (#13798719) Journal
    Couldn't they just give them a placebo? It's amazing what calcium carbonate, magnesium sulphate and a bit of food colouring can cure.
  • by deglr6328 ( 150198 ) on Saturday October 15, 2005 @07:20PM (#13799492)
    "If such chemicals, such as peroxy radical, superoxide, etc are in fact produced, then to the extent that they get past your outer skin and react with live cells, the chemicals will produce cancerous and mutagenic lesions. If the chemcals get to the layer of living cells which is continously gowing and dividing to produce new skin, you would have to worry about skin cancers......"

    What tosh. By this reasoning the hydrogen peroxide solutions available in every drug store in the world are horribly carcinogenic brews just waiting to induce nasty insidious tumors at the slightest touch to the skin.

And it should be the law: If you use the word `paradigm' without knowing what the dictionary says it means, you go to jail. No exceptions. -- David Jones

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