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story
Manwe's Herald writes
"The first draft of the dog genome sequence has been deposited into free public databases for use by biomedical and veterinary researchers around the globe, the National Human Genome Research Institute (NHGRI), one of the National Institutes of Health (NIH), announced today."
Open Source Pets (Score:4, Funny)
Re:Open Source Pets (Score:4, Informative)
Open source is not a new idea for the academic sciences - they've been operating on that principle for a couple hundred years now.
Just One Step Closer To Chocobos! (Score:1)
Re:Just One Step Closer To Chocobos! (Score:1)
Re:Open Source Pets. What sort of license? (Score:1)
I see a SCO case coming (Score:1)
Genealogy of a Mutt (Score:4, Interesting)
Re:Genealogy of a Mutt (Score:5, Informative)
Much of the point of looking at dogs is to understand the differences between breeds, like why collies are born knowing how to herd sheep while Shih-Tzus are completely stupid all their lives. So, to the degree that your dog is related to breeds they've looked at, you can get started as soon as they clean the data enough to post it to dbSNP.
Re:Genealogy of a Mutt (Score:1)
Re:Genealogy of a Mutt (Score:5, Interesting)
This study was significant because it was the first to be able to unambiguously identify dog DNA by breed reliably. Previous attempts using smaller numbers of SNPs tended to be very innacurate.
The biggest result of the dog genome is for human medicine. Geneticists have been pushing for dog genomes (they're already working on a second dog breed genome) for years. Purebreed dogs are a geneticists dream. Each breed has distintive features as well as characteristic diseases such as arthritis, nerve degeneration and cardiovascular disease. Purebreed dogs are also basically giant inbred families with meticulous documentation about their lineage. Having dog genomes actually has a great deal of potential to revolutionize human medicine as a result.
Oh, fun lets DNA mark our pets. (Score:2)
Re:Oh, fun lets DNA mark our pets. (Score:2)
In case of slashdotting.... (Score:4, Funny)
ATCTATCTC
TYGACTATA
ATCTATCTA
TGATCTACG
TGA
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Re:In case of slashdotting.... (Score:5, Funny)
This must be one of those new dogs with six nucleotides.
What does "Y" pair with?
Re:In case of slashdotting.... (Score:2)
Degeneracies, IUPAC codes, etc. (Score:5, Informative)
A full listing of IUPAC codes may be found here [www.mun.ca].
Re:Degeneracies, IUPAC codes, etc. (Score:2)
Re:Degeneracies, IUPAC codes, etc. (Score:1, Funny)
And geeks everywhere rejoyce... (Score:4, Funny)
Re:And geeks everywhere rejoyce... (Score:2)
Re:And geeks everywhere rejoyce... (Score:2)
This means big changes in the world of dogs (Score:1, Funny)
I wonder how long it is before a joint effort by animal rights owners and fanatical christians start complaining about whether man understanding this much of Dog is morally right.
Somebody (Score:3, Funny)
Massive number of chromosomes (Score:5, Interesting)
I'm a cat person, myself. Cats, being contrary by nature, allowed themselves to be cloned, but then came out looking completely different [cbsnews.com] because coat color and pattern is determined after conception.
Re:Massive number of chromosomes (Score:5, Funny)
And in case any of this seems like irrelevant ivory-tower stuff, it has some very real applications, e.g., they may be able to modify the human genome to remove some of these same behaviors from the males of our own species.
Is allergy relief in sight? (Score:2, Insightful)
I hope we will eventually be able isolate the allergen, find the sequence that codes for it (assuming it is a protein), and alter it such that it doesn't adversely affect the dog's health and keeps people like me from having horrible reactions to them.
Re:Is allergy relief in sight? (Score:4, Insightful)
I'd rather hope for the protein to be identified, as you said, and then for some sort of medicine created that specifically binds to that protein and blocks your immune response. Repeat for cats, plants, whatever else people are allergic to, you've got a nice allergy spray that really really works.
Re:Is allergy relief in sight? (Score:1)
Re:Is allergy relief in sight? (Score:2)
Re:Is allergy relief in sight? (Score:2)
Among the hypoallergenic breeds to choose from: the Standard Poodle, Giant Schnauzer, Afghan Hound, Irish Water Spaniel, Komondor, Miniature Poodle, Standard Schnauzer, Portuguese Water Dog, Puli, Soft-coated Wheaten Terrier, Kerry Blue and Bedlington Terriers, Toy Poodle, Miniature Schnauzer, Bichon Frise, Mexican Hairless and Chinese Crested Dog.
"Hypoallergenic" is the fancy way to say "doesn't affect people with allergies".
meh (Score:1)
But will this allow Poodles to fly? (Score:3, Funny)
Ola! And welcome to Raul's Wild Kingdom! Today, we're teaching poodles how to fly! Are you ready Fifi? Are psyched? Here we gooooooo..... (Throws poodle out of window)
yipe yipe yipe yipe yipe yipe *thump*
You know, sometimes it takes 'em a leetle longer to get it right.
More or Fewer Experiments on Dogs? (Score:2, Flamebait)
I don't know if it's still true, but at one time vivisection of dogs was common practice in medical and dental schools in the United States so students could "see how organs worked."
I admit it, I have a soft spot for other social mammals of a certain brain size. I can understand lower primates as an unfortunate necessity for human
Re:More or Fewer Experiments on Dogs? (Score:2)
Re:More or Fewer Experiments on Dogs? (Score:2)
somebody's got to kill the animals and it's a no-brainer that it is physically and psychologically easier for a (Western) lab tech to kill a rat than kill a dog.
Actually, I've heard that there is a movement to stop using rats...
Major research universities and labratories have started to use lawyers instead of rats for their experiments. There are three reasons why they are favoring lawyers over rats.
1. There are more lawyers than rats.
2. They find that lab technicians do not become as emotionall
Finally... (Score:1)
great ! (Score:2)
now, with genetic engineering, we can create dogs of arbitrary size, color, aspect, and abilities. Oh, wait...
research (Score:1)
Also, I'm not sure how exactly this genome assembly was conducted, but maybe the people doing the research could benefit from using Stanford University's Folding@Home program [stanford.edu] (or at least the distributed computing idea behind it) to do additional testing in this